Steven G. Sayson, Ph.D.

Grant: #UM1TR005265 & institutional cost share Investigators:Sayson, Steven 06-01-2026 -05-31-2028 CCTST K Scholars Award Neutrophil heterogeneity and lung injury during Pneumocystis Pneumonia Role:PI Active Type:Grant

Grant: #5R61AI187097 Investigators:Smulian, Alan George; Sayson, Steven 12-01-2024 -11-30-2027 National Institute of Allergy and Infectious Diseases Development of a Molecular Toolbox for Pneumocystis Role:Co-PI Active Type:Grant

Grant: #5R61AI187113 Investigators:Smulian, Alan George; Molestina, Robert; Porollo, Alexey; Sayson, Steven 12-20-2024 -11-30-2027 National Institute of Allergy and Infectious Diseases Alveolar organoids and metabolomic-driven cultivation of Pneumocystis species Role:Co-I Active Type:Grant

Grant: #1R01HL176858 Investigators:Smulian, Alan George; Porollo, Alexey; Sayson, Steven 08-01-2025 -05-31-2029 National Heart Lung and Blood Institute Elucidating the Sexual Cycle of HIV/AIDS-Related Pneumocystis Pneumonia Role:Co-I Active

Grant: #5R01NS134804 Investigators:Harris, Greg; Sayson, Steven 08-01-2026 -12-31-2028 National Institute of Neurological Disorders and Stroke Developing multi-cue piezoelectric PVDF-TrFE biomaterials for peripheral nerve repair Role:Co-I Active Type:Grant

Investigators:Smulian, Alan George; Sayson, Steven 12-01-2023 -Bad Format: 20261131 Dr. Ralph and Marian Falk Medical Research Trust Targeting the Sexual Cycle of Pneumocystis for Treatment, Prevention, and Diagnosis of Pneumocystis Pneumonia Role:Co-I Active Type:Grant

Grant: #1R61AI187097 Investigators:Cushion, Melanie; Sayson, Steven; Smulian, George 12-01-2024 -11-30-2027 National Institute of Allergy and Infectious Diseases Development of a Molecular Toolbox for Pneumocystis Role:Collaborator 801670.00 Active Level:Federal

Peer Reviewed Publications

Sayson, Steven G; Ashbaugh, Alan; Bauer, Lillian C; Smulian, A George  (2025). Extracellular vesicle-mediated delivery of genetic material for transformation and CRISPR/Cas9-based gene editing in Pneumocystis murina. mBio, 16 (11) , e0182525More Information

Albee, Aaron W; Sayson, Steven G; Ashbaugh, Alan; Wolf, Nicholas J; Porollo, Aleksey; Smulian, George; Cushion, Melanie T  (2025). Single-cell RNA sequencing defines developmental progression and reproductive transitions of Pneumocystis carinii. Microbiology spectrum, 13 (10) , e0127725More Information

Sayson, S. G.; Ashbaugh, A.; Cushion, M. T.  (2024). Extracellular vesicles from Pneumocystis carinii-infected rats impair fungal viability but are dispensable for macrophage functions. Microbiol Spectr, e0365323More Information

Sayson, Steven G; Ashbaugh, Alan; Porollo, Aleksey; Smulian, George; Cushion, Melanie T  (2024). Pneumocystis murina promotes inflammasome formation and NETosis during Pneumocystis pneumonia. mBio, e0140924More Information

Porollo, Aleksey; Sayson, Steven G; Ashbaugh, Alan; Rebholz, Sandra; Landero Figueroa, Julio A; Cushion, Melanie T  (2024). Insights into copper sensing and tolerance in Pneumocystis species. Frontiers in microbiology, 15, 1383737More Information

Cushion, Melanie T; Ashbaugh, Alan; Sayson, Steven G; Mosley, Christopher; Hauser, Philippe M  (2022). Anidulafungin Treatment Blocks the Sexual Cycle of Pneumocystis murina and Prevents Growth and Survival without Rescue by an Alternative Mode of Replication. Microbiology spectrum, e0290622More Information

Cushion, Melanie T; Tisdale-Macioce, Nikeya; Sayson, Steven G; Porollo, Aleksey  (2021). The Persistent Challenge of Pneumocystis Growth Outside the Mammalian Lung: Past and Future Approaches. Frontiers in microbiology, 12, 681474More Information

Cushion, Melanie T; Ashbaugh, Alan; Hendrix, Keeley; Linke, Michael J; Tisdale, Nikeya; Sayson, Steven G; Porollo, Aleksey  (2018). Gene Expression of Pneumocystis murina after Treatment with Anidulafungin Results in Strong Signals for Sexual Reproduction, Cell Wall Integrity, and Cell Cycle Arrest, Indicating a Requirement for Ascus Formation for Proliferation. Antimicrobial Agents and Chemotherapy, 62 (5) More Information