Pier Paolo Paolo Scaglioni , MD

Medical Degree: University of Modena Medical School Modena, Italy, 1989

Residency: University of Modena Medical School Modena, Italy, 1994 (Internal Medicine)

Research Fellowship: Massachusetts General Hospital Boston, MA, 1998 (Virology)

Residency: Montefiore Medical Center Bronx, NY, 2001 (Internal Medicine)

Fellowship: Memorial Sloan Kettering Cancer Center New York, NY, 2005 (Hematology/Oncology)

Research Fellowship: Memorial Sloan Kettering Cancer Center New York, NY, 2005 (Cancer Biology and Genetics)

American Board of Internal Medicine (Medical Oncology) (Certification Date: 11-03-2004 ) - (Recertification Date: to 03-21-2019 )

Hematology and Oncology

Leukemia

Acute Lymphocytic Leukemia

Acute Myeloid Leukemia

Amyloidosis

Castleman Disease

Chronic Lymphocytic Leukemia

Chronic Myelogenous Leukemia

Lymphadenopathy

Lymphoma

M Protein

Macrocytosis

Macroglobulinemia

Mantle Cell Lymphoma

Mediastinal Adenopathy

Monoclonal gammopathy

Monoclonal protein

M-Spike

Mycosis Fugoides

Myelodysplastic Syndrome

Myeloma

Myeloproliferative Disorder

Paraproteinemia

Plasma Cell Disorder

Polycythemia vera

Proteinuria

Sideroblastic anemia

T-cell lymphoma

Internal Medicine

Medical Oncology

Hematology/Oncology and Bone Marrow Transplant, Acute Myelogenous and lymphoblastic leukemias. 
For information about the lab see: Pier Paolo Scaglioni Lab

2005 -2006 Instructor, Dept of Medicine, Hematology Service, Memorial Sloan Kettering Cancer Center, New York, NY

2006 -2014 Assistant Professor, Dept of Medicine, Div of Hematology Oncology, UT Southwestern Medical Center, Dallas, TX

2014 -2018 Associate Professor, Dept of Medicine, Div of Hematology Oncology, UT Southwestern Medical Center, Dallas, TX

2018 - Professor and Division Director, Dept of Medicine, Div of Hematology Oncology, University of Cincinnati College of Medicine, Cincinnati, OH

1998 -2001 Intern Resident, Internal Medicine, Montefiore Medical Center, Bronx, NY

2001 -2005 Fellow, Hematology Oncology, Memorial Sloan Kettering Cancer Center, New York, NY

2006 -2014 Assistant Professor, Dept of Medicine, Div of Hematology Oncology, UT Southwestern Medical Center, Dallas, TX

2014 -2018 Associate Professor, Dept of Medicine, Div of Hematology Oncology, UT Southwestern Medical Center, Dallas, TX

2014 -2018 Associate Professor, Dept of Medicine, Div of Hematology Oncology, Parkland Memorial Hospital, Dallas, TX

2018 - Professor, Dept of Medicine, Div of Hematology Oncology, University of Cincinnati Medical Center, Cincinnati, OH

2018 - Professor, Dept of Medicine, Div of Hematology Oncology, UC Health West Chester Hospital, West Chester, OH

2018 - Medical Director, Dept of Medicine, Div of Hematology Oncology, UC Health Barret Cancer Center, Cincinnati, OH

2020 - Interim Director, Dept of Medicine, Div of Hematology Oncology, The George L. Strike Stem Cell Transplant and Pheresis Center at the University of Cincinnati, Cincinnati, OH

2015 -2018 Co-Leader Cancer Cell Networks, Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX

2016 -2018 Director, Cancer Center Grand Rounds, Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX

Grant: #R35CA197734 Investigators:Scaglioni, Pier Paolo 07-01-2021 -08-31-2022 National Cancer Institute Targeted Therapy for Leukemia Role:PI 170582.23 Hold Level:Federal

Grant: #R01CA213442 Investigators:Scaglioni, Pier Paolo 07-01-2021 -02-28-2022 National Cancer Institute Unlocking the Potential of PI3K Inhibition in CLL Role:PI 84130.60 Hold Level:Federal

Investigators:Scaglioni, Pier Paolo 08-01-2021 -12-31-2023 American Cancer Society - National Chapter Investigating the Role of BCL3 in Ibrutinib Resistant CLL Role:PI 137500.02 Hold Level:Non Profit

Grant: #K99CA246083 (Actual PI: Abdul-Aziz, Amina) Investigators:Scaglioni, Pier Paolo -01-31-2022 National Cancer Institute Impact of the senescent bone marrow microenvironment in AML biology Role:PI 0.00 Hold Level:Federal

Grant: #R01CA259845 Investigators:Scaglioni, Pier Paolo 09-01-2021 -08-31-2026 National Cancer Institute Fatty acid metabolism regulates ferroptosis in mutant KRAS lung cancer Role:PI 484380.00 Hold Level:Federal

Grant: #CYNK-001-AML-001 03-01-2022 -03-01-2025 Celularity Inc. A PHASE I MULTI-DOSE STUDY OF HUMAN PLACENTAL HEMATOPOIETIC STEM CELL DERIVED NATURAL KILLER CELLS (CYNK-001) WITH OR WITHOUT RECOMBINANT HUMAN INTERLEUKIN-2 (RHIL-2) IN ADULTS WITH PRIMARY OR SECONDA Role:PI 607228.20 Hold Level:Industry

Grant: #CYNK-001-AML-001 03-01-2022 -03-01-2025 Celularity Inc. A PHASE I MULTI-DOSE STUDY OF HUMAN PLACENTAL HEMATOPOIETIC STEM CELL DERIVED NATURAL KILLER CELLS (CYNK-001) WITH OR WITHOUT RECOMBINANT HUMAN INTERLEUKIN-2 (RHIL-2) IN ADULTS WITH PRIMARY OR SECONDA Role:PI 607228.20 Hold Level:Industry

Grant: #T32CA236764-01 Investigators:Bogdanov, Vladimir; Qi, Xiaoyang; Scaglioni, Pier 07-05-2019 -06-30-2025 National Cancer Institute Post-Graduate Hematology/Oncology Translational (PG-HOT) Training Program Role:PI 2085874.00 Active Level:Federal

Peer Reviewed Publications

Gupta, Arjun; Saltarski, Jessica M; White, Michael A; Scaglioni, Pier P; Gerber, David E (2017. ) Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, , 12 (9 ) ,1446-1450 More Information

Rabellino, Andrea; Andreani, Cristina; Scaglioni, Pier Paolo (2017. ) The Role of PIAS SUMO E3-Ligases in Cancer.Cancer research, , 77 (7 ) ,1542-1547 More Information

Tang, Ke-Jing; Constanzo, Jerfiz D; Venkateswaran, Niranjan; Melegari, Margherita; Ilcheva, Mariya; Morales, Julio C; Skoulidis, Ferdinandos; Heymach, John V; Boothman, David A; Scaglioni, Pier Paolo (2016. ) Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research, , 22 (23 ) ,5851-5863 More Information

Kim, Jimi; McMillan, Elizabeth; Kim, Hyun Seok; Venkateswaran, Niranjan; Makkar, Gurbani; Rodriguez-Canales, Jaime; Villalobos, Pamela; Neggers, Jasper Edgar; Mendiratta, Saurabh; Wei, Shuguang; Landesman, Yosef; Senapedis, William; Baloglu, Erkan; Chow, Chi-Wan B; Frink, Robin E; Gao, Boning; Roth, Michael; Minna, John D; Daelemans, Dirk; Wistuba, Ignacio I; Posner, Bruce A; Scaglioni, Pier Paolo; White, Michael A (2016. ) XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.Nature, , 538 (7623 ) ,114-117 More Information

Padanad, Mahesh S; Konstantinidou, Georgia; Venkateswaran, Niranjan; Melegari, Margherita; Rindhe, Smita; Mitsche, Matthew; Yang, Chendong; Batten, Kimberly; Huffman, Kenneth E; Liu, Jingwen; Tang, Ximing; Rodriguez-Canales, Jaime; Kalhor, Neda; Shay, Jerry W; Minna, John D; McDonald, Jeffrey; Wistuba, Ignacio I; DeBerardinis, Ralph J; Scaglioni, Pier Paolo (2016. ) Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.Cell reports, , 16 (6 ) ,1614-1628 More Information

Constanzo, Jerfiz D; Deng, Mi; Rindhe, Smita; Tang, Ke-Jing; Zhang, Cheng-Cheng; Scaglioni, Pier Paolo (2016. ) Pias1 is essential for erythroid and vascular development in the mouse embryo.Developmental biology, , 415 (1 ) ,98-110 More Information

Rabellino, Andrea; Melegari, Margherita; Tompkins, Van S; Chen, Weina; Van Ness, Brian G; Teruya-Feldstein, Julie; Conacci-Sorrell, Maralice; Janz, Siegfried; Scaglioni, Pier Paolo (2016. ) PIAS1 Promotes Lymphomagenesis through MYC Upregulation.Cell reports, , 15 (10 ) ,2266-2278 More Information

Scaglioni, Priscila Tessmer; Badiale-Furlong, Eliana (2016. ) Rice husk as an adsorbent: A new analytical approach to determine aflatoxins in milk.Talanta, , 152 ,423-31 More Information

Constanzo, Jerfiz D; Tang, Ke-Jing; Rindhe, Smita; Melegari, Margherita; Liu, Hui; Tang, Ximing; Rodriguez-Canales, Jaime; Wistuba, Ignacio; Scaglioni, Pier Paolo (2016. ) PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer.Neoplasia (New York, N.Y.), , 18 (5 ) ,282-93 More Information

Chakrabarti, Gaurab; Moore, Zachary R; Luo, Xiuquan; Ilcheva, Mariya; Ali, Aktar; Padanad, Mahesh; Zhou, Yunyun; Xie, Yang; Burma, Sandeep; Scaglioni, Pier P; Cantley, Lewis C; DeBerardinis, Ralph J; Kimmelman, Alec C; Lyssiotis, Costas A; Boothman, David A (2015. ) Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.Cancer & metabolism, , 3 ,12 More Information

Rajagopalan, Kartik N; Egnatchik, Robert A; Calvaruso, Maria A; Wasti, Ajla T; Padanad, Mahesh S; Boroughs, Lindsey K; Ko, Bookyung; Hensley, Christopher T; Acar, Melih; Hu, Zeping; Jiang, Lei; Pascual, Juan M; Scaglioni, Pier Paolo; DeBerardinis, Ralph J (2015. ) Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells.Cancer & metabolism, , 3 ,7 More Information

Ramadori, Giorgio; Konstantinidou, Georgia; Venkateswaran, Niranjan; Biscotti, Tommasina; Morlock, Lorraine; Galié, Mirco; Williams, Noelle S; Luchetti, Michele; Santinelli, Alfredo; Scaglioni, Pier Paolo; Coppari, Roberto (2015. ) Diet-induced unresolved ER stress hinders KRAS-driven lung tumorigenesis.Cell metabolism, , 21 (1 ) ,117-25 More Information

Scaglioni, P T; Becker-Algeri, T; Drunkler, D; Badiale-Furlong, E (2014. ) Aflatoxin B? and M? in milk.Analytica chimica acta, , 829 ,68-74 More Information

Schuster, Katja; Venkateswaran, Niranjan; Rabellino, Andrea; Girard, Luc; Peña-Llopis, Samuel; Scaglioni, Pier Paolo (2014. ) Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.Molecular cancer research : MCR, , 12 (6 ) ,912-23 More Information

Konstantinidou, Georgia; Ramadori, Giorgio; Torti, Francesca; Kangasniemi, Kim; Ramirez, Rachel E; Cai, Yiran; Behrens, Carmen; Dellinger, Michael T; Brekken, Rolf A; Wistuba, Ignacio I; Heguy, Adriana; Teruya-Feldstein, Julie; Scaglioni, Pier Paolo (2013. ) RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.Cancer discovery, , 3 (4 ) ,444-57 More Information

Rabellino, Andrea; Scaglioni, Pier Paolo (2013. ) PML Degradation: Multiple Ways to Eliminate PML.Frontiers in oncology, , 3 ,60 More Information

Scaglioni, Pier Paolo; Rabellino, Andrea; Yung, Thomas M; Bernardi, Rosa; Choi, Sooyeon; Konstantinidou, Georgia; Nardella, Caterina; Cheng, Ke; Pandolfi, Pier Paolo (2012. ) Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence.EMBO molecular medicine, , 4 (7 ) ,594-602 More Information

Rabellino, Andrea; Carter, Brandon; Konstantinidou, Georgia; Wu, Shwu-Yuan; Rimessi, Alessandro; Byers, Lauren A; Heymach, John V; Girard, Luc; Chiang, Cheng-Ming; Teruya-Feldstein, Julie; Scaglioni, Pier Paolo (2012. ) The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.Cancer research, , 72 (9 ) ,2275-84 More Information

Schuster, K; Zheng, J; Arbini, A A; Zhang, C C; Scaglioni, P P (2011. ) Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro and in vivo.Blood cancer journal, , 1 (9 ) ,e34 More Information

Naina, Harris V; Levitt, Daniel; Vusirikala, Madhuri; Anderson, Larry D; Scaglioni, Pier Paolo; Kirk, Angela; Collins, Robert H (2011. ) Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 29 (18 ) ,e534-6 More Information

Scaglioni, Pier Paolo; Cai, Lu Fan; Majid, Samia M; Yung, Thomas M; Socci, Nicholas D; Kogan, Scott C; Kopelovich, Levy; Pandolfi, Pier Paolo (2011. ) Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model.Genes & cancer, , 2 (2 ) ,160-5 More Information

Sullivan, James P; Spinola, Monica; Dodge, Michael; Raso, Maria G; Behrens, Carmen; Gao, Boning; Schuster, Katja; Shao, Chunli; Larsen, Jill E; Sullivan, Laura A; Honorio, Sofia; Xie, Yang; Scaglioni, Pier P; DiMaio, J Michael; Gazdar, Adi F; Shay, Jerry W; Wistuba, Ignacio I; Minna, John D (2010. ) Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.Cancer research, , 70 (23 ) ,9937-48 More Information

Konstantinidou, Georgia; Bey, Erik A; Rabellino, Andrea; Schuster, Katja; Maira, Michael S; Gazdar, Adi F; Amici, Augusto; Boothman, David A; Scaglioni, Pier Paolo (2009. ) Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations.Cancer research, , 69 (19 ) ,7644-52 More Information

Scaglioni, P P; Yung, T M; Choi, S; Choi, S C; Baldini, C; Konstantinidou, G; Pandolfi, P P (2008. ) CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor.Molecular and cellular biochemistry, , 316 (1-2 ) ,149-54 More Information

Scaglioni, P P; Pandolfi, P P (2007. ) The theory of APL revisited. Current topics in microbiology and immunology, , 313 ,85-100

Shen, Tian Huai; Lin, Hui-Kuan; Scaglioni, Pier Paolo; Yung, Thomas M; Pandolfi, Pier Paolo (2006. ) The mechanisms of PML-nuclear body formation.Molecular cell, , 24 (3 ) ,331-9 More Information

Scaglioni, Pier Paolo; Yung, Thomas M; Cai, Lu Fan; Erdjument-Bromage, Hediye; Kaufman, Andrew J; Singh, Bhuvanesh; Teruya-Feldstein, Julie; Tempst, Paul; Pandolfi, Pier Paolo (2006. ) A CK2-dependent mechanism for degradation of the PML tumor suppressor.Cell, , 126 (2 ) ,269-83 More Information

Trotman, Lloyd C; Alimonti, Andrea; Scaglioni, Pier Paolo; Koutcher, Jason A; Cordon-Cardo, Carlos; Pandolfi, Pier Paolo (2006. ) Identification of a tumour suppressor network opposing nuclear Akt function.Nature, , 441 (7092 ) ,523-7 More Information

Matsushita, Hiromichi; Scaglioni, Pier Paolo; Bhaumik, Mantu; Rego, Eduardo M; Cai, Lu Fan; Majid, Samia M; Miyachi, Hayato; Kakizuka, Akira; Miller, Wilson H; Pandolfi, Pier Paolo (2006. ) In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.The Journal of experimental medicine, , 203 (4 ) ,821-8 More Information

Bernardi, Rosa; Scaglioni, Pier Paolo; Bergmann, Stephan; Horn, Henning F; Vousden, Karen H; Pandolfi, Pier Paolo (2004. ) PML regulates p53 stability by sequestering Mdm2 to the nucleolus.Nature cell biology, , 6 (7 ) ,665-72 More Information

Gurrieri, Carmela; Capodieci, Paola; Bernardi, Rosa; Scaglioni, Pier Paolo; Nafa, Khedoudja; Rush, Laura J; Verbel, David A; Cordon-Cardo, Carlos; Pandolfi, Pier Paolo (2004. ) Loss of the tumor suppressor PML in human cancers of multiple histologic origins. Journal of the National Cancer Institute, , 96 (4 ) ,269-79

Scaglioni, Pier Paolo; Pandolfi, Pier Paolo (2003. ) Medicine: taking apart a cancer protein.Nature, , 426 (6966 ) ,512-3 More Information

Mohr, L; Yoon, S K; Eastman, S J; Chu, Q; Scheule, R K; Scaglioni, P P; Geissler, M; Heintges, T; Blum, H E; Wands, J R (2001. ) Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice.Human gene therapy, , 12 (7 ) ,799-809 More Information

Melegari, M; Scaglioni, P P; Wands, J R (1998. ) Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. Journal of virology, , 72 (3 ) ,1737-43

Melegari, M; Scaglioni, P P; Wands, J R (1998. ) Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective.Hepatology (Baltimore, Md.), , 27 (2 ) ,628-33 More Information

Wands, J R; Geissler, M; Putlitz, J Z; Blum, H; von Weizsäcker, F; Mohr, L; Yoon, S K; Melegari, M; Scaglioni, P P (1997. ) Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection. Journal of gastroenterology and hepatology, , 12 (9-10 ) ,S354-69

Scaglioni, P P; Melegari, M; Wands, J R (1997. ) Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame.Virology, , 233 (2 ) ,374-81 More Information

Melegari, M; Scaglioni, P P; Wands, J R (1997. ) The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted. Journal of virology, , 71 (7 ) ,5449-54

Scaglioni, P P; Melegari, M; Wands, J R (1997. ) Posttranscriptional regulation of hepatitis B virus replication by the precore protein. Journal of virology, , 71 (1 ) ,345-53

Scaglioni, P; Melegari, M; Takahashi, M; Chowdhury, J R; Wands, J (1996. ) Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents.Hepatology (Baltimore, Md.), , 24 (5 ) ,1010-7 More Information

Scaglioni, P P; Melegari, M; Wands, J R (1996. ) Recent advances in the molecular biology of hepatitis B virus. Bailliere's clinical gastroenterology, , 10 (2 ) ,207-25

Scaglioni, P P; Melegari, M; Wands, J R (1994. ) Characterization of hepatitis B virus core mutants that inhibit viral replication.Virology, , 205 (1 ) ,112-20 More Information

Melegari, M; Scaglioni, P P; Pasquinelli, C; Manenti, F; Villa, E (1992. ) Hepatitis B virus specific transcripts in peripheral blood mononuclear cells. Archives of virology. Supplementum, , 4 ,46-9

Villa, E; Melegari, M; Ferretti, I; Vecchi, C; Scaglioni, P P; De Palma, M; Manenti, F (1992. ) Presence of HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH). Archives of virology. Supplementum, , 4 ,247-8

Villa, E; Melegari, M; Scaglioni, P P; Trande, P; Cesaro, P; Manenti, F Hepatocellular carcinoma: risk factors other than HBV. The Italian journal of gastroenterology, , 23 (7 ) ,457-60

Melegari, M; Jung, M C; Schneider, R; Santantonio, T; Bagnulo, S; Luchena, N; Pastore, G; Pape, G; Scaglioni, P P; Villa, E (1991. ) Conserved core protein sequences in hepatitis B virus infected patients without anti-HBc. Journal of hepatology, , 13 (2 ) ,187-91

Villa, E; Ferretti, I; De Palma, M; Melegari, M; Scaglioni, P P; Trande, P; Vecchi, C; Fratti, N; Manenti, F (1991. ) HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH). Journal of hepatology, , 13 (2 ) ,256-9

Pasquinelli, C; Melegari, M; Villa, E; Scaglioni, P P; Seidenari, M; Mongiardo, N; De Rienzo, B; Manenti, F (1990. ) Hepatitis B virus infection of peripheral blood mononuclear cells is common in acute and chronic hepatitis. Journal of medical virology, , 31 (2 ) ,135-40

Melegari, M; Scaglioni, P P; Mao, G P; Pasquinelli, C; Baldini, G [Estrogen receptors in the human liver]. Medicina (Florence, Italy), , 10 (2 ) ,154-7

Pasquinelli, C; Melegari, M; Villa, E; Seidenari, M; Scaglioni, P P; Tiribelli, C; Crocé, L S; Manenti, F (1990. ) Detection of hepatitis B virus transcripts in patients with chronic liver disease. Journal of hepatology, , 10 (2 ) ,180-5

Scaglioni, P P; Melegari, M; Mao, G; Pasquinelli, C [HBV DNA in mononuclear cells of peripheral blood in acute hepatitis B: a comparative analysis of Southern blot and polymerase chain reaction (PCR)]. Medicina (Florence, Italy), , 10 (1 ) ,32-4

Rabellino, Andrea; Andreani, Cristina; Scaglioni, Pier Paolo (2020. ) Roles of Ubiquitination and SUMOylation in the Regulation of Angiogenesis.Current issues in molecular biology, , 35 ,109-126 More Information

Gerber, David E; Camidge, D Ross; Morgensztern, Daniel; Cetnar, Jeremey; Kelly, Ronan J; Ramalingam, Suresh S; Spigel, David R; Jeong, Woondong; Scaglioni, Pier P; Zhang, Song; Li, Marilyn; Weaver, David T; Vaikus, Louis; Keegan, Mitchell; Horobin, Joanna C; Burns, Timothy F (2020. ) Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer.Lung cancer (Amsterdam, Netherlands), , 139 ,60-67 More Information

Lafita-Navarro, M Carmen; Kim, Min; Borenstein-Auerbach, Nofit; Venkateswaran, Niranjan; Hao, Yi-Heng; Ray, Roshni; Brabletz, Thomas; Scaglioni, Pier Paolo; Shay, Jerry W; Conacci-Sorrell, Maralice (2018. ) The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells.Genes & development, , 32 (19-20 ) ,1303-1308 More Information

Tumati, Vasu; Trivedi, Lakshya; Li, Hsiao-Ching; Patel, Prapti; Scaglioni, Pier P; Vusirikala, Madhuri; Sadeghi, Navid; Rizvi, Syed; Chen, Weina; Wachsmann, Jason; Collins, Robert; Desai, Neil B (2018. ) Patterns of Failure in Patients With Double Hit or Double Expressor Lymphomas: Implications for Radiation Therapy.International journal of radiation oncology, biology, physics, , 100 (5 ) ,1126-1132 More Information

Constanzo, Jerfiz D; Tang, Ke-Jing; Rindhe, Smita; Melegari, Margherita; Liu, Hui; Tang, Ximing; Rodriguez-Canales, Jaime; Wistuba, Ignacio; Scaglioni, Pier Paolo (2016. ) Corrigendum to "PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer" [Neoplasia 18 (2016) 282-293].Neoplasia (New York, N.Y.), , 18 (7 ) ,457 More Information

Shen, Tian Huai; Lin, Hui-Kuan; Scaglioni, Pier Paolo; Yung, Thomas M; Pandolfi, Pier Paolo (2006. ) The Mechanisms of PML-Nuclear Body Formation.Molecular cell, , 24 (5 ) ,805 More Information

Constanzo J.D.;Tang K.j.;Rindhe S.;Melegari M.;Liu H.;Tang X.;Rodriguez-Canales J.;Wistuba I.;Scaglioni P.P. (07-01-2016. ) Corrigendum to “PIAS1-FAK Interaction Promotes the Survival and Progression of Non–Small Cell Lung C.Neoplasia (United States), , 18 (7 ) ,457 More Information

Constanzo J.;Tang K.;Rindhe S.;Melegari M.;Liu H.;Tang X.;Rodriguez-Canales J.;Wistuba I.;Scaglioni P. (05-01-2016. ) PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer.Neoplasia (United States), , 18 (5 ) ,282-293 More Information

Rabellino A.;Scaglioni P. (12-24-2013. ) PML degradation: Multiple ways to eliminate PML.Frontiers in Oncology, , 3 MAR , More Information

Schuster K.;Zheng J.;Arbini A.;Zhang C.;Scaglioni P. (09-01-2011. ) Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro .Blood Cancer Journal, , 1 (9 ) , More Information

Scaglioni P.P.;Cai L.F.;Majid S.M.;Yung T.M.;Socci N.D.;Kogan S.C.;Kopelovich L.;Pandolfi P.P. (07-12-2011. ) Treatment with 5-azacytidine accelerates acute promyelocytic Leukemia leukemogenesis in a transgenic.Genes and Cancer, , 2 (2 ) ,160-165 More Information

Scaglioni P.P.;Yung T.M.;Choi S.;Baldini C.;Konstantinidou G.;Pandolfi P.P. (05-06-2009. ) Erratum: CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor.Molecular and Cellular Biochemistry, , 327 (1-2 ) ,279 More Information

Shen T.H.;Lin H.K.;Scaglioni P.P.;Yung T.M.;Pandolfi P.P. (12-08-2006. ) The Mechanisms of PML-Nuclear Body Formation (DOI:10.1016/j.molcel.2006.09.013).Molecular Cell, , 24 (5 ) ,805 More Information

Wands J.R.;Geissler M.;Putlitz J.Z.U.;Blum H.;Von Weizsäcker F.;Mohr L.;Yoon S.K.;Melegari M.;Scaglioni P.P. (01-01-1997. ) Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection.Journal of Gastroenterology and Hepatology (Australia), , 12 (9-10 ) , More Information

Mesko, Marcia F; Balbinot, Fernanda P; Scaglioni, Priscila T; Nascimento, Mariele S; Picoloto, Rochele S; da Costa, Vanize C (2020. ) Determination of halogens and sulfur in honey: a green analytical method using a single analysis.Analytical and bioanalytical chemistry, , More Information

1989 Prize for Italian Researchers younger than 35 years of age Medicina, Firenze

1991 Research Fellowship Terme di Chianciano S.p.A.

2001 Citation in recognition as an outstanding House Officer Montefiore Medical Center/A. Einstein College of Medicine

2003 Young Investigator Award American Society of Clinical Oncology

2003 Oncology Fellows Award Cancer and leukemia Group B

2003 Travel Award American Society of Hematology

2004 Clinical Scholars Training Program in Biomedical Research Memorial Sloan-Kettering Cancer Center Post-doctoral fellowship

2004 Diner Award Doris Duke Foundation

2004 Travel Award American Society of Hematology

2008 The Gibbie Award The Ryan Gibson Foundation

2012 The Gibbie Award The Ryan Gibson Foundation

2013 Friends' Award in Cancer Research Friends of the Comprehensive Cancer Center

(Student Award Committee ) Member Type:University/College Service Level:University 2012 -2017

(Steering Committee, Cancer Biology Graduate Program ) Member Type:University/College Service Level:University 2015 -2018

(Scientific Advisory Committee, Basic Science Working Group ) Member Type:University/College Service Level:University 2020

1991: Member American Association for the Advancement of Science,

2010: Member American Association for Cancer Research,

2008 -2018: Texas Medical Association,

2018: Cincinnati Medical Society,

Pier Paolo Scaglioni, MD

Academic - Vontz Center for Molecular Studies
3125 Eden Ave
Cincinnati  Ohio, 45267