Aaron Seitz

Aaron Patrick Seitz , MD

Assistant Professor of Clinical

Medical Sciences Building
231 Albert Sabin Way
Cincinnati, Ohio 45267-0558
Phone 513-558-4206
Email aaron.seitz@uc.edu

Education

Bachelor: Iowa State University Ames, IA, 2007 (Chemical Engineering)

Master: University of Cincinnati Cincinnati, OH, 2008 (Physiology)

Medical Degree: University of Cincinnati College of Medicine Cincinnati, OH, 2012

Residency: University of CIncinnati Cincinnati, OH , 2020 (General Surgery)

Fellowship: University Of Cincinnati Cincinnati, OH , 2021 (Surgical Critical Care )

Certifications

American Board of Surgery (Certification Date: 11-18-2020 )

American Board of Surgery (Surgery Critical Care) (Certification Date: 10-04-2021 )

Clinical Interests

Critical Care Surgery

General Surgery

Trauma

Abdominal Hernia

Acalculous Cholecystitis

Appendicitis

Bile Duct Stones

Biliary Dyskinesia

Billiary Disease

Bleeding in the Small Bowel

Bowel Obstruction

Cholecystolithiasis

Choledocholithiasis

Cholelithiasis

Colonic Diverticulitis

Diverticular Disease

Diverticulitis

Femoral Hernia

Fractured Ribs

Gallbladder Inflammation (Cholecystitis)

Gallstones

Groin Hernias

Hernia

Lung Collapse (Pneumothorax)

Peritonitis

Pilonidal Cyst

Pilonidal Dimple

Pilonidal Sinus

Pyloric Stenosis

Traumatic Injury

Umbilical Hernia

Ventral Hernia

Gallbladder Disease

Specialities

Surgery-Critical Care

Publications

Peer Reviewed Publications

Seitz, Aaron P; Grassmé, Heike; Edwards, Michael J; Pewzner-Jung, Yael; Gulbins, Erich (2015. ) Ceramide and sphingosine in pulmonary infections.Biological chemistry, , 396 (6-7 ) ,611-20 More Information

Managò, Antonella; Becker, Katrin Anne; Carpinteiro, Alexander; Wilker, Barbara; Soddemann, Matthias; Seitz, Aaron P; Edwards, Michael J; Grassmé, Heike; Szabò, Ildiko; Gulbins, Erich (2015. ) Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase.Antioxidants & redox signaling, , 22 (13 ) ,1097-110 More Information

Kasten, Kevin R; Prakash, Priya S; Unsinger, Jacqueline; Goetzman, Holly S; England, Lisa G; Cave, Cindy M; Seitz, Aaron P; Mazuski, Cristina N; Zhou, Tony T; Morre, Michel; Hotchkiss, Richard S; Hildeman, David A; Caldwell, Charles C (2010. ) Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis.Infection and immunity, , 78 (11 ) ,4714-22 More Information

Kasten, Kevin R; Tschöp, Johannes; Goetzman, Holly S; England, Lisa G; Dattilo, Jonathan R; Cave, Cindy M; Seitz, Aaron P; Hildeman, David A; Caldwell, Charles C (2010. ) T-cell activation differentially mediates the host response to sepsis.Shock (Augusta, Ga.), , 34 (4 ) ,377-83 More Information

Rice, Teresa C; Pugh, Amanda M; Xia, Brent T; Seitz, Aaron P; Whitacre, Brynne E; Gulbins, Erich; Caldwell, Charles C (2017. ) Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection.Journal of the American College of Surgeons, , 225 (4 ) ,538-547 More Information

Kunz, Natalia; Xia, Brent T; Kalies, Kai-Uwe; Klinger, Matthias; Gemoll, Timo; Habermann, Jens K; Whitacre, Brynne E; Seitz, Aaron P; Kalies, Kathrin; Caldwell, Charles C (2017. ) Cell-Derived Nanoparticles are Endogenous Modulators of Sepsis With Therapeutic Potential.Shock (Augusta, Ga.), , 48 (3 ) ,346-354 More Information

Grassmé, Heike; Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Riethmüller, Joachim; Gardner, Aaron; Seitz, Aaron P; Steinmann, Joerg; Lang, Stephan; Ward, Christopher; Schuchman, Edward H; Caldwell, Charles C; Kamler, Markus; Edwards, Michael J; Brodlie, Malcolm; Gulbins, Erich (2017. ) ?1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections.Cell host & microbe, , 21 (6 ) ,707-718.e8 More Information

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Pritts, Timothy A (2017. ) pH modulation ameliorates the red blood cell storage lesion in a murine model of transfusion.The Journal of surgical research, , 212 ,54-59 More Information

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A (2017. ) Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion.Shock (Augusta, Ga.), , 47 (5 ) ,632-637 More Information

Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C (2016. ) Frontline Science: Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection.Journal of leukocyte biology, , 100 (6 ) ,1233-1237 More Information

Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Gulbins, Erich; Edwards, Michael J (2016. ) Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, , 39 (4 ) ,1262-70 More Information

Becker, Katrin Anne; Riethmüller, Joachim; Seitz, Aaron P; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C; Edwards, Michael J; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich (2018. ) Sphingolipids as targets for inhalation treatment of cystic fibrosis.Advanced drug delivery reviews, , More Information

Rice, Teresa C; Pugh, Amanda M; Seitz, Aaron P; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C (2017. ) Sphingosine rescues aged mice from pulmonary pseudomonas infection.The Journal of surgical research, , 219 ,354-359 More Information

Hoehn, Richard S; Seitz, Aaron P; Singer, Kathleen E; Thompson, Jonathan R; Watkins, Brad M (2019. ) Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary?.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, , 23 (8 ) ,1541-1546 More Information

Seitz, Aaron P; Schumacher, Fabian; Baker, Jennifer; Soddemann, Matthias; Wilker, Barbara; Caldwell, Charles C; Gobble, Ryan M; Kamler, Markus; Becker, Katrin Anne; Beck, Sascha; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich (2019. ) Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia.Journal of molecular medicine (Berlin, Germany), , 97 (8 ) ,1195-1211 More Information

Baker, Jennifer E; Boudreau, Ryan M; Seitz, Aaron P; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era?.Surgical infections, , 19 (8 ) ,792-803 More Information

Hoehn R.S.;Seitz A.P.;Singer K.E.;Thompson J.R.;Watkins B.M. (08-15-2019. ) Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary?.Journal of Gastrointestinal Surgery, , 23 (8 ) ,1541-1546 More Information

Becker K.;Fahsel B.;Kemper H.;Mayeres J.;Li C.;Wilker B.;Keitsch S.;Soddemann M.;Sehl C.;Kohnen M.;Edwards M.;Grassmé H.;Caldwell C.;Seitz A.;Fraunholz M.;Gulbins E. (01-01-2018. ) Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas.Infection and Immunity, , 86 (1 ) , More Information

Becker K.;Li X.;Seitz A.;Steinmann J.;Koch A.;Schuchman E.;Kamler M.;Edwards M.;Caldwell C.;Gulbins E. (11-01-2017. ) Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine.Cellular Physiology and Biochemistry, , 43 (4 ) ,1603-1616 More Information

Martin G.;Boudreau R.;Couch C.;Becker K.;Edwards M.;Caldwell C.;Gulbins E.;Seitz A. (10-01-2017. ) Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic.Biochimie, , 141 ,91-96 More Information

Tavakoli Tabazavareh S.;Seitz A.;Jernigan P.;Sehl C.;Keitsch S.;Lang S.;Kahl B.;Edwards M.;Grassmé H.;Gulbins E.;Becker K. (05-17-2016. ) Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi.Cellular Physiology and Biochemistry, , 38 (6 ) ,2094-2102 More Information

Carpinteiro A.;Beckmann N.;Seitz A.;Hessler G.;Wilker B.;Soddemann M.;Helfrich I.;Edelmann B.;Gulbins E.;Becker K. (01-01-2016. ) Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis.Cellular Physiology and Biochemistry, , 38 (1 ) ,1-14 More Information

Li C.;Peng H.;Japtok L.;Seitz A.;Riehle A.;Wilker B.;Soddemann M.;Kleuser B.;Edwards M.;Lammas D.;Zhang Y.;Gulbins E.;Grassme H. (01-01-2016. ) Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis .Frontiers in Bioscience - Elite, , 8 (2 ) ,311-325

Hoehn R.; Seitz A.; Singer K.; Thompson J.; Watkins B. (08-15-2019. ) Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary?.Journal of Gastrointestinal Surgery, , 23 (8 ) ,1541-1546 More Information

Becker K.; Caldwell C.; Edwards M.; Fahsel B.; Fraunholz M.; Grassmé H.; Gulbins E.; Keitsch S.; Kemper H.; Kohnen M.; Li C.; Mayeres J.; Sehl C.; Seitz A.; Soddemann M.; Wilker B. (01-01-2018. ) Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas.Infection and Immunity, , 86 (1 ) , More Information

Becker K.; Caldwell C.; Edwards M.; Gulbins E.; Kamler M.; Koch A.; Li X.; Schuchman E.; Seitz A.; Steinmann J. (11-01-2017. ) Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine.Cellular Physiology and Biochemistry, , 43 (4 ) ,1603-1616 More Information

Becker K.; Boudreau R.; Caldwell C.; Couch C.; Edwards M.; Gulbins E.; Martin G.; Seitz A. (10-01-2017. ) Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic.Biochimie, , 141 ,91-96 More Information

Becker K.; Edwards M.; Grassmé H.; Gulbins E.; Jernigan P.; Kahl B.; Keitsch S.; Lang S.; Sehl C.; Seitz A.; Tavakoli Tabazavareh S. (05-17-2016. ) Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi.Cellular Physiology and Biochemistry, , 38 (6 ) ,2094-2102 More Information

Becker K.; Beckmann N.; Carpinteiro A.; Edelmann B.; Gulbins E.; Helfrich I.; Hessler G.; Seitz A.; Soddemann M.; Wilker B. (01-01-2016. ) Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis.Cellular Physiology and Biochemistry, , 38 (1 ) ,1-14 More Information

Edwards M.; Grassme H.; Gulbins E.; Japtok L.; Kleuser B.; Lammas D.; Li C.; Peng H.; Riehle A.; Seitz A.; Soddemann M.; Wilker B.; Zhang Y. (01-01-2016. ) Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis .Frontiers in Bioscience - Elite, , 8 (2 ) ,311-325

Niziolek, Grace M; Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Makley, Amy T; Gulbins, Erich; Edwards, Michael J; Goodman, Michael D (2021. ) The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury.The Journal of surgical research, , 259 ,296-304 More Information

Baker, Jennifer E; Seitz, Aaron P; Boudreau, Ryan M; Skinner, Mitchell J; Beydoun, Ahmed; Kaval, Necati; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J; Gobble, Ryan M (2020. ) Doxycycline-Coated Silicone Breast Implants Reduce Acute Surgical-Site Infection and Inflammation.Plastic and reconstructive surgery, , 146 (5 ) ,1029-1041 More Information

Seitz, Aaron; Baker, Jennifer E; Levinsky, Nick C; Morris, Mackenzie C; Edwards, Michael J; Gulbins, Erich; Blakeman, Thomas C; Rodriquez, Dario; Branson, Richard D; Goodman, Michael (2021. ) Antimicrobial coating prevents ventilator-associated pneumonia in a 72 hour large animal model.The Journal of surgical research, , 267 ,424-431 More Information

Book Chapter

Seitz A (2017 ) Wound healing The Mont Reid Surgical Handbook, 7th ed .Elsevier

Seitz A (2017 ) Surgical infection The Mont Reid Surgical Handbook, 7th ed .Elsevier

Contact Information

Academic - Medical Sciences Building
231 Albert Sabin Way
Cincinnati  Ohio, 45267-0558
Phone: 513-558-4206
aaron.seitz@uc.edu