George Shaw III

George J Shaw III

Associate Professor of Emergency Medicine, Tenured

Engineering Research Cntr

CEAS - Biomedical Eng - 0012

University of Cincinnati College of Medicine
Department of Emergency Medicine
Cincinnati, Ohio 45267-0769

Education

Medical Degree, Georgetown University School of Medicine

Residency, University of Cincinnati/University Hospital

Research and Practice Interests

UC Health Clinical Focus

Emergency Medicine

UC Health Specialities

Emergency Medicine

Certifications

American Board of Emergency Medicine

06/06/2002

Research Support

Grant: #1 K02 NS056253-01 Investigators:Shaw, George 09-05-2006 -12-31-2011 National Heart, Lung and Blood Institute Imaging Study of Combination Thrombolytic Therapy Role:PI $840,984.00 Closed Level:Federal

Grant: #2002-UC-30-03-A0-S0-E0 Investigators:Shaw, George 05-01-2002 -04-30-2005 Whitaker Foundation A Visual Study of Ultrasound Enhanced Thrombolysis in an In-Vitro Clot Model Role:PI $255,393.00 Closed Level:Private Non-Profit

Grant: #P50 NS044283 Investigators:Broderick, Joseph; Clark, Joseph; Flaherty, Matthew; Holland, Christy; Jauch, Edward; Lindsell, Christopher; Lu, Aigang; Pancioli, Arthur; Pyne-Geithman, Gail Jean; Shaw, George 08-01-2008 -04-30-2014 National Institute of Neurological Disorders and Stroke Recanalization Therapies and Markers of Stroke Outcome Role:Collaborator $8,710,370.00 Active Level:Federal

Grant: #R01 NS047603 Investigators:Holland, Christy; Mast, T. Douglas; Shaw, George; Wagner, Kenneth 02-15-2009 -01-31-2014 National Institute of Neurological Disorders and Stroke Ultrasound-Assisted Thrombolysis for Stroke Therapy Role:Collaborator $2,324,085.00 Active Level:Federal

Grant: #3 P50 NS044283-07S1 Investigators:Broderick, Joseph; Flaherty, Matthew; Pancioli, Arthur; Shaw, George 09-01-2009 -08-31-2011 National Institute of Neurological Disorders and Stroke Recanalization Therapies and Markers of Stroke Outcome Role:Collaborator $111,195.00 Closed Level:Federal

Grant: #5-75959 / P50 NS049060-06 Investigators:Shaw, George 08-01-2010 -07-31-2012 National Institute of Neurological Disorders and Stroke Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART) Role:PI $68,932.00 Closed Level:Federal

Grant: #URC Interdisciplinary Awards Investigators:Papautsky, Ian; Shaw, George 04-01-2014 -03-31-2015 UC's University Research Council Ultrasound-Mediated Thrombolysis Using Microfluidic Plasmin-Loaded Echogenic Liposomes Role:PI $25,000.00 Active Level:Internal UC

Grant: #SBIR Ph I / NSF IIP-1520285 Investigators:Shaw, George 10-01-2015 -12-31-2015 National Science Foundation Novel Device for Monitoring Brain Hemorrhage Using Radio Waves Role:PI $35,101.00 Active Level:Federal

Publications

Peer Reviewed Publications

Meunier, Jason M; Wenker, Evan; Lindsell, Christopher J; Shaw, George J (2013. )Individual lytic efficacy of recombinant tissue plasminogen activator in an in vitro human clot model: rate of "nonresponse".Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, ,20 (5 ),449-55

Korfhagen, Joseph J; Kandadai, Madhuvanthi A; Clark, Joseph F; Adeoye, Opeolu; Shaw, George J (2013. )A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage.Journal of neuroscience methods, ,213 (1 ),132-7

Kandadai, Madhuvanthi A; Raymond, Jason L; Shaw, George J (2012. )Comparison of electrical conductivities of various brain phantom gels: Developing a 'Brain Gel Model'.Materials science & engineering. C, Materials for biological applications, ,32 (8 ),2664-2667

Meunier, Jason M; Chang, Wan-Tsu W; Bluett, Brent; Wenker, Evan; Lindsell, Christopher J; Shaw, George J (2012. )Temperature Affects Thrombolytic Efficacy Using rt-PA and Eptifibatide, an In Vitro Study.Therapeutic hypothermia and temperature management, ,2 (3 ),112-118

Kandadai, Madhuvanthi A; Meunier, Jason; Lindsell, Christopher J; Shaw, George J; Elkind, Mitchell S V (2012. )Short-term high-dose effect of lovastatin on thrombolysis by rt-PA in a human whole-blood in vitro clot model. Current neurovascular research, ,9 (3 ),207-13

Meunier, Jason M; Holland, Christy K; Porter, Tyrone M; Lindsell, Christopher J; Shaw, George J (2011. )Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model. Current neurovascular research, ,8 (4 ),305-12

Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Pancioli, Arthur M; Holland, Christy K (2010. )Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study.Thrombosis research, ,126 (4 ),e305-11

Shaw, George J; Meunier, Jason M; Huang, Shao-Ling; Lindsell, Christopher J; McPherson, David D; Holland, Christy K (2009. )Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes.Thrombosis research, ,124 (3 ),306-10

Shaw, George J; Sperling, Matthew; Meunier, Jason M (2009. )Long-term stability of recombinant tissue plasminogen activator at -80 C.BMC research notes, ,2 ,117

Meunier, Jason M; Holland, Christy K; Pancioli, Arthur M; Lindsell, Christopher J; Shaw, George J (2009. )Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots.Thrombosis research, ,123 (3 ),528-36

Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Holland, Christy K (2008. )Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis.Ultrasound in medicine & biology, ,34 (11 ),1783-92

Ammi, Azzdine Y; Mast, T Douglas; Huang, I-Hua; Abruzzo, Todd A; Coussios, Constantin-C; Shaw, George J; Holland, Christy K (2008. )Characterization of ultrasound propagation through ex-vivo human temporal bone.Ultrasound in medicine & biology, ,34 (10 ),1578-89

Ma, Marek; Lindsell, Christopher J; Rosenberry, Clark M; Shaw, George J; Zemlan, Frank P (2008. )Serum cleaved tau does not predict postconcussion syndrome after mild traumatic brain injury.The American journal of emergency medicine, ,26 (7 ),763-8

Holland, Christy K; Vaidya, Sampada S; Datta, Saurabh; Coussios, Constantin-C; Shaw, George J (2008. )Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model.Thrombosis research, ,121 (5 ),663-73

Shaw, George J; Dhamija, Ashima; Bavani, Nazli; Wagner, Kenneth R; Holland, Christy K (2007. )Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis.Physics in medicine and biology, ,52 (11 ),2953-67

Meunier, Jason M; Holland, Christy K; Lindsell, Christopher J; Shaw, George J (2007. )Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model.Ultrasound in medicine & biology, ,33 (4 ),576-83

Shaw, George J; Bavani, Nazli; Dhamija, Ashima; Lindsell, Christopher J (2006. )Effect of mild hypothermia on the thrombolytic efficacy of 120 kHz ultrasound enhanced thrombolysis in an in-vitro human clot model.Thrombosis research, ,117 (5 ),603-8

Cheng, Jason Y; Shaw, George J; Holland, Christy K (2005. )In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model.Acoustics research letters online : ARLO, ,6 (1 ),25-29

Shaw, George J; Jauch, Edward C; Zemlan, Frank P (2002. )Serum cleaved tau protein levels and clinical outcome in adult patients with closed head injury. Annals of emergency medicine, ,39 (3 ),254-7

Contact Information

Academic - University of Cincinnati College of Medicine
Department of Emergency Medicine
CincinnatiĀ  Ohio, 45267-0769
Phone: 513-558-5281
Fax: 513-558-5791
George.Shaw@uc.edu