Davendra Pratap Singh Sohal , MD

Dr. Sohal is a board-certified medical oncologist, focusing on the treatment of patients with gastrointestinal cancers, with a special interest in clinical trials of cutting-edge drugs and novel approaches to cancer therapy. He has joined UC Health as an Associate Professor of Medicine. His roles focus on developing the clinical trials portfolio as the Director of Experimental Therapeutics, and improving patient access, referrals, and services as the Clinic Medical Director.

Dr. Sohal earned his medical degree from the All India Institute of Medical Sciences in New Delhi, India. He completed residency training and a year as a Chief Resident in Internal Medicine at the Jacobi Medical Center of the Albert Einstein College of Medicine in Bronx, NY. He then completed a fellowship in Hematology/Oncology at the University of Pennsylvania in Philadelphia, PA. Dr. Sohal has also completed graduate training in epidemiology and biostatistics at the University of Alabama at Birmingham.

Prior to joining UC Health, Dr. Sohal was at the Cleveland Clinic Taussig Cancer Institute, where he served as the founding Director of the Clinical Genomics Program. He is the principal investigator of several clinical trials for patients, both in GI cancers and genomics, including national cooperative group, investigator-initiated, and industry-sponsored studies. His key accolades include an American Society of Clinical Oncology (ASCO) Young Investigator Award, being Chair of the American Board of Internal Medicine (ABIM) Medical Oncology Self-Assessment Committee, the Co-Chair of the American Society of Clinical Oncology (ASCO) Clinical Practice Guidelines Panel for Metastatic Pancreatic Cancer, an Investigator of the Pancreas Task Force of the Gastrointestinal Steering Committee of the National Cancer Institute, a Member of the Hepatobiliary Guidelines Committee of the National Comprehensive Cancer Network (NCCN), Chair of the Research Committee of the Precision Medicine Exchange Consortium, and serving on the Editorial Board of JCO Precision Oncology.
 

Medical Degree: All India Institute of Medical Sciences New Delhi, India, 2003

Master's Degree: University of Alabama at Birmingham Birmingham, AL, 2005 (Public Health)

Resident, Internal Medicine: Jacobi Medical Center, Albert Einstein College of Medicine Bronx, NY, 2008

Chief Resident, Internal Medicine: Jacobi Medical Center, Albert Einstein College of Medicine Bronx, NY, 2009

Fellow, Hematology and Oncology: University of Pennsylvania Philadelphia, PA, 2012

American Board of Internal Medicine (Medical Oncology) (Certification Date: 10-24-2012 )

Esophageal Cancer

Hematology and Oncology

Ampullary Cancer

Anal Cancer

Appendix Cancer

Biliary Cancer

Cholangiocarcinoma

Colon Cancer

Intestinal Cancer

Liver Cancer

Neuroendocrine Cancer

Pancreatic Cancer

Peritoneal Cancer

Rectal Cancer

Small Bowel Cancer

Stomach Cancer

Internal Medicine

Medical Oncology

07-2012 -09-2019 Assistant - Associate Professor, Director, Clinical Genomics Program, Cleveland Clinic, Cleveland, OH.

10-2019 - Associate Professor, Director of Experimental Therapeutics, Clinic Medical Director, Division of Hematology Oncology, University of Cincinnati, Cincinnati, OH.

Grant: #R01FD006817 Investigators:Sohal, Davendra 09-10-2020 -07-31-2024 Food and Drug Administration Phase I/II clinical evaluation of ABTL0812, a novel PI3K/Akt/mTOR inhibitor, with a unique mechanism of action in pancreatic cancer Role:PI $470,000.00 Awarded Level:Federal

Grant: #Sub #1014562 / UG1CA189974 Investigators:Sohal, Davendra 08-01-2019 -07-31-2025 National Cancer Institute SWOG CTI - Sohal Role:PI 36000.00 Awarded Level:Federal

Investigators:Olowokure, Olugbenga; Sohal, Davendra 09-01-2021 -08-31-2027 Pancreatic Cancer Network University of Cincinnati Cancer Center Role:PI 0.00 Hold Level:Non Profit

Investigators:Bogdanov, Vladimir; Sohal, Davendra 11-30-2021 -11-29-2023 Dr. Ralph and Marian Falk Medical Research Trust Preclinical development of a first-in-class humanized antibody targeting alternatively spliced tissue factor Role:Collaborator 0.00 Hold Level:Non Profit

Grant: #R01CA199064 Investigators:Sohal, Davendra 07-01-2021 -06-30-2022 National Cancer Institute Tumor Subtypes and Therapy Response in Pancreatic Cancer Role:PI 21044.67 Hold Level:Federal

Grant: #Precision Promise Investigators:Sohal, Davendra 02-01-2022 -01-31-2025 Labcorp Drug Development, Inc. PRECISION PROMISESM PLATFORM TRIAL FOR METASTATIC PANCREATIC CANCER, Including Sub-protocols A-F Role:PI 600124.45 Hold Level:Industry

Grant: #UCCC-GI-20-02 -02-18-2025 University of Arizona An Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma: A Phase II Trial Role:PI 0.00 Hold Level:Higher Education

Grant: #UCCC-GI-20-02 -02-18-2025 University of Arizona An Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma: A Phase II Trial Role:PI 0.00 Hold Level:Higher Education

Grant: #SHR-A1904-I-104 03-01-2022 -02-28-2025 HengRui Ltd. AN OPEN-LABEL, SINGLE-ARM, MULTI-CENTER PHASEI/IIA CLINICAL STUDY TO EVALUATE THE SAFETY,TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OFSHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS Role:PI 2260672.70 Hold Level:Industry

Grant: #SHR-A1904-I-104 03-01-2022 -02-28-2025 HengRui Ltd. AN OPEN-LABEL, SINGLE-ARM, MULTI-CENTER PHASEI/IIA CLINICAL STUDY TO EVALUATE THE SAFETY,TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OFSHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS Role:PI 2260672.70 Hold Level:Industry

Grant: #PRECISIONPROMISE 07-01-2022 -06-30-2025 Pancreatic Cancer Action Network, Inc PRECISION PROMISESM PLATFORM TRIAL FOR METASTATIC PANCREATIC CANCER Role:PI 114450.00 Hold Level:Industry

Grant: #PRECISIONPROMISE 07-01-2022 -06-30-2025 Pancreatic Cancer Action Network, Inc PRECISION PROMISESM PLATFORM TRIAL FOR METASTATIC PANCREATIC CANCER Role:PI 114450.00 Hold Level:Industry

07-01-2022 -06-30-2025 Pancreatic Cancer Action Network, Inc PRECISION PROMISESM PLATFORM TRIAL FOR METASTATIC PANCREATIC CANCER Role:PI 371766.25 Hold Level:Industry

07-01-2022 -06-30-2025 Pancreatic Cancer Action Network, Inc PRECISION PROMISESM PLATFORM TRIAL FOR METASTATIC PANCREATIC CANCER Role:PI 371766.25 Hold Level:Industry

Grant: #TTX-080-001 Investigators:Sohal, Davendra 12-01-2021 -12-01-2024 Tizona Pharmaceuticals A Phase 1a/1b Dose Escalation/Expansion Study of TTX-080, an HLA-G Antagonist, as Monotherapy & in Combination w/Pembrolizumab or Cetuximab in Pts w/Advanced Solid Refractory/Resistant Malignancies Role:PI 436967.58 Hold Level:Industry

Grant: #NC410-02 07-01-2022 -06-30-2025 Clinical Trial Services, Inc. A TWO-PART, PHASE 1A/B, OPEN-LABEL, MULTICENTER TRIAL EVALUATING PHARMACOKINETICS, SAFETY AND EFFICACY OF PF-07284890 (ARRY-461) IN PARTICIPANTS WITH BRAF V600-MUTANT SOLID TUMORS WITH AND WITHOUT BRA Role:PI 1832476.54 Hold Level:Industry

Grant: #NC410-02 07-01-2022 -06-30-2025 Clinical Trial Services, Inc. A TWO-PART, PHASE 1A/B, OPEN-LABEL, MULTICENTER TRIAL EVALUATING PHARMACOKINETICS, SAFETY AND EFFICACY OF PF-07284890 (ARRY-461) IN PARTICIPANTS WITH BRAF V600-MUTANT SOLID TUMORS WITH AND WITHOUT BRA Role:PI 1832476.54 Hold Level:Industry

Grant: #R7075-ONC-2009 03-01-2022 -03-01-2025 Regeneron A PHASE 1/2 STUDY OF REGN7075 (EGFRxCD28 COSTIMULATORYBISPECIFIC ANTIBODY) IN COMBINATION WITH CEMIPLIMAB INPATIENTS WITH ADVANCED SOLID TUMORS Role:PI 1864624.77 Hold Level:Industry

Grant: #R7075-ONC-2009 03-01-2022 -03-01-2025 Regeneron A PHASE 1/2 STUDY OF REGN7075 (EGFRxCD28 COSTIMULATORYBISPECIFIC ANTIBODY) IN COMBINATION WITH CEMIPLIMAB INPATIENTS WITH ADVANCED SOLID TUMORS Role:PI 1864624.77 Hold Level:Industry

Grant: #BXG-350.AG 01-20-2023 -01-29-2028 Bexion Pharmaceuticals A Phase 1b/2 Placebo Controlled, Double Blinded Study on the Efficacy and Safety of BXQ-350 in Combination with mFOLFOX7 and Bevacizumab in Newly Diagnosed Metastatic Colorectal Carcinoma Role:PI 0.00 Active Level:Industry

Grant: #BXG-350.AG 01-20-2023 -01-29-2028 Bexion Pharmaceuticals A Phase 1b/2 Placebo Controlled, Double Blinded Study on the Efficacy and Safety of BXQ-350 in Combination with mFOLFOX7 and Bevacizumab in Newly Diagnosed Metastatic Colorectal Carcinoma Role:PI 0.00 Active Level:Industry

Grant: #TT420C1206 01-20-2023 -01-28-2028 TransThera Sciences (Nanjing), Inc. A Phase II, Open Label, Multicenter Study to Evaluate the Efficacy and Safety of TT-00420 Tablet in Adult Patients With Advanced Cholangiocarcinoma Role:PI 0.00 Active Level:Industry

Grant: #TT420C1206 01-20-2023 -01-28-2028 TransThera Sciences (Nanjing), Inc. A Phase II, Open Label, Multicenter Study to Evaluate the Efficacy and Safety of TT-00420 Tablet in Adult Patients With Advanced Cholangiocarcinoma Role:PI 0.00 Active Level:Industry

Grant: #MRTX0902 Investigators:Sohal, Davendra 04-19-2023 -04-19-2026 Mirati Therapeutics, Inc. A Phase 1/2 Multiple Expansion Cohort Trial of the SOS1 Inhibitor MRTX0902 in Patients with Advanced Solid Tumors Harboring Mutations in the KRAS-MAPK Pathway Role:PI 0.00 Hold Level:Industry

Grant: #TOS-358-001 Investigators:Sohal, Davendra 06-27-2023 -06-27-2026 Totus Medicines, Inc. A Study to Evaluate the Safety and Tolerability of the Covalent Phosphoinositide-3-Kinase (PI3K)-alpha Inhibitor, TOS-358, in Adult Subjects with Select Solid Tumors Role:PI 576641.46 Hold Level:Industry

Grant: #TAK-676-1002 Investigators:Sohal, Davendra 08-11-2023 -08-11-2026 Takeda Development Center Americas, Inc. Takeda Development Center Americas, Inc_ICON_Sohal_TAK-676-1002_US_CTA Role:PI 805436.58 Hold Level:Industry

Grant: #D926UC00001 Investigators:Sohal, Davendra 07-20-2023 -07-20-2026 AstraZeneca Pharmaceuticals LP A Phase II, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anti-cancer Agents in Patients with Advanced S Role:PI 343641.42 Active Level:Industry

Grant: #RPL-004 Investigators:Sohal, Davendra 08-23-2023 -08-23-2026 Replimune, Inc. A Phase 2 Clinical Trial Investigating Oncolytic Immunotherapy in Combination with Atezolizumab and Bevacizumab for the Treatment of Patients with Advanced Microsatellite Stable and Mismatch Repair Pr Role:PI 1173175.40 Hold Level:Industry

Grant: #RP3-003_RPOWER-HCC Investigators:Sohal, Davendra 08-25-2023 -08-25-2026 Replimune, Inc. Replimune, Inc. RP3-003 CTA Role:PI 1878735.50 Hold Level:Industry

Grant: #TAC01-CLDN18.2-04 Investigators:Sohal, Davendra 08-15-2023 -08-15-2026 Triumvira Immunologics, Inc. A Phase 1/2 Study Investigating the Safety and Efficacy of Autologous TAC T Cells in Subjects with Unresectable, Locally Advanced or Metastatic Claudin 18.2+ Solid Tumors Role:PI 1227630.01 Hold Level:Industry

Grant: #AWD00002060 (UM1CA186690) Investigators:Sohal, Davendra 03-01-2023 -02-29-2024 National Cancer Institute ETCTN Supplement Role:PI 40000.00 Hold Level:Federal

Grant: #102 Investigators:Sohal, Davendra 11-20-2023 -11-20-2026 Carisma Therapeutics, Inc. An Open-Label, Single-Arm Study of Autologous Anti-HER2 Chimeric Antigen ReceptorMonocytes (CT-0525), in Participants With HER2 Over Expressing Solid Tumors Role:PI 381864.06 Hold Level:Industry

Grant: #SWOG Network Group Operations Center of the NCTN Investigators:Chaudhary, Rekha; Sohal, Davendra 03-01-2019 -02-28-2025 National Cancer Institute SWOG CTI Role:PI 465000.00 Active Level:Federal

Grant: #TAC01-HER2-03_4732-0003 Investigators:Sohal, Davendra; Wise-Draper, Trisha 01-12-2023 -01-28-2028 Triumvira Immunologics, Inc. A Phase I/II Trial Investigating Safety and Efficacy of Autologous TAC T Cells Targeting HER2 in Relapsed or Refractory Solid Tumors (TACTIC-2) Role:PI 0.00 Active Level:Industry

Grant: #GO44479 Investigators:Sohal, Davendra 02-01-2024 -02-01-2027 Genentech, Inc. A PHASE II, OPEN-LABEL, MULTICENTER, RANDOMIZED STUDY OF THE EFFICACY AND SAFETY OF ADJUVANT AUTOGENE CEVUMERAN PLUS ATEZOLIZUMAB AND mFOLFIRINOX VERSUS mFOLFIRINOX ALONE IN PATIENTS WITH RESECTED PAN Role:PI 1380459.00 Hold Level:Industry

Grant: #RP3-301 Investigators:Sohal, Davendra 04-03-2024 -04-15-2024 Replimune, Inc. An Open-Label, Multicenter, Phase 1 Study of RP3 as a Single Agent and in Combination with PD-1 Blockade in Patients with Solid Tumors Role:PI 18250.00 Hold Level:Industry

Grant: #CO44668 Investigators:Sohal, Davendra 04-05-2024 -04-05-2027 Genentech, Inc. A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING ATEZOLIZUMAB AND BEVACIZUMAB, WITH OR WITHOUT TIRAGOLUMAB, IN PATIENTS WITH UNTREATED LOCALLY ADVANCED OR METASTATIC HEPATOCE Role:PI 1204822.80 Hold Level:Industry

Grant: #TCR-21-01 Investigators:Sohal, Davendra 04-29-2024 -05-29-2024 TCR2 Therapeutics A PHASE 1/2 SINGLE ARM OPEN-LABEL CLINICAL TRIAL OF TC-510 IN PATIENTS WITH ADVANCED MESOTHELIN-EXPRESSING CANCER - CANCELED STUDY - START-UP AGREEMENT ONLY Role:PI 19400.00 Active Level:Industry

Grant: #RMC-GI-102 Investigators:Sohal, Davendra 07-22-2024 -07-22-2027 Revolution Medicine, Inc. A Platform Study of RAS(ON) Inhibitors in Patients with Gastrointestinal Solid Tumors Role:PI 1318945.48 Hold Level:Industry

Grant: #C5181001 Investigators:Sohal, Davendra 05-02-2024 -08-30-2024 Pfizer, Inc. Start-up fees agreement for canceled study Role:PI 22150.00 Hold Level:Industry

Grant: #C5421001 Investigators:Sohal, Davendra 12-03-2024 -12-03-2027 Pfizer, Inc. A PHASE 1 OPEN-LABEL STUDY OF PF-07934040 AS A SINGLE-AGENT AND IN COMBINATION WITH OTHER TARGETED AGENTS IN PARTICIPANTS WITH ADVANCED SOLID TUMORS HARBORING MUTATIONS IN THE KRAS GENE Role:PI 617144.34 Hold Level:Industry

Peer Reviewed Publications

Hu, Zishuo Ian; Bendell, Johanna C; Bullock, Andrea; LoConte, Noelle K; Hatoum, Hassan; Ritch, Paul; Hool, Hugo; Leach, Joseph W; Sanchez, James; Sohal, Davendra P S; Strickler, John; Patel, Ravindranath; Wang-Gillam, Andrea; Firdaus, Irfan; Yu, Kenneth H; Kapoun, Ann M; Holmgren, Eric; Zhou, Lei; Dupont, Jakob; Picozzi, Vincent; Sahai, Vaibhav; O'Reilly, Eileen M (2019. ) A randomized phase II trial of nab-paclitaxel and gemcitabine with tarextumab or placebo in patients with untreated metastatic pancreatic cancer.Cancer medicine, , 8 (11 ) ,5148-5157 More Information

McHugh, Kelsey E; Dermawan, Josephine K; Cheng, Yu-Wei; Cruise, Michael; Sohal, Davendra P S; Reynolds, Jordan P (2019. ) Molecular testing in metastatic colorectal adenocarcinoma cytology cell pellets.Diagnostic cytopathology, , More Information

Brar, Gagandeep; Blais, Edik M; Joseph Bender, R; Brody, Jonathan R; Sohal, Davendra; Madhavan, Subha; Picozzi, Vincent J; Hendifar, Andrew E; Chung, Vincent M; Halverson, David; Mikhail, Sameh; Matrisian, Lynn M; Rahib, Lola; Petricoin, Emanuel; Pishvaian, Michael J (2019. ) Multi-omic molecular comparison of primary versus metastatic pancreatic tumours.British journal of cancer, , 121 (3 ) ,264-270 More Information

Mukhija, Dhruvika; Nagpal, Sajan Jiv Singh; Sohal, Davendra P S (2019. ) Epidemiology, Tumor Characteristics, and Survival in Patients With Primary Pancreatic Lymphoma: A Large Population-based Study Using the SEER Database.American journal of clinical oncology, , 42 (5 ) ,454-458 More Information

Benson, Al B; D'Angelica, Michael I; Abbott, Daniel E; Abrams, Thomas A; Alberts, Steven R; Anaya, Daniel A; Anders, Robert; Are, Chandrakanth; Brown, Daniel; Chang, Daniel T; Cloyd, Jordan; Covey, Anne M; Hawkins, William; Iyer, Renuka; Jacob, Rojymon; Karachristos, Andreas; Kelley, R Kate; Kim, Robin; Palta, Manisha; Park, James O; Sahai, Vaibhav; Schefter, Tracey; Sicklick, Jason K; Singh, Gagandeep; Sohal, Davendra; Stein, Stacey; Tian, G Gary; Vauthey, Jean-Nicolas; Venook, Alan P; Hammond, Lydia J; Darlow, Susan D (2019. ) Guidelines Insights: Hepatobiliary Cancers, Version 2.2019.Journal of the National Comprehensive Cancer Network : JNCCN, , 17 (4 ) ,302-310 More Information

Pishvaian, Michael J; Bender, Robert J; Halverson, David; Rahib, Lola; Hendifar, Andrew E; Mikhail, Sameh; Chung, Vincent; Picozzi, Vincent J; Sohal, Davendra; Blais, Edik M; Mason, Kimberly; Lyons, Emily E; Matrisian, Lynn M; Brody, Jonathan R; Madhavan, Subha; Petricoin, Emanuel F (2018. ) Molecular Profiling of Patients with Pancreatic Cancer: Initial Results from the Know Your Tumor Initiative.Clinical cancer research : an official journal of the American Association for Cancer Research, , 24 (20 ) ,5018-5027 More Information

Mukhija, Dhruvika; Sohal, Davendra P S; Khorana, Alok A (2018. ) Adjuvant Treatment in Potentially Curable Pancreatic Cancer: Need to Include Tumor Location in the Equation?.Pancreas, , 47 (8 ) ,e50-e52 More Information

Sohal, Davendra P S; Kennedy, Erin B; Khorana, Alok; Copur, Mehmet S; Crane, Christopher H; Garrido-Laguna, Ignacio; Krishnamurthi, Smitha; Moravek, Cassadie; O'Reilly, Eileen M; Philip, Philip A; Ramanathan, Ramesh K; Ruggiero, Joseph T; Shah, Manish A; Urba, Susan; Uronis, Hope E; Lau, Michelle W; Laheru, Daniel (2018. ) Metastatic Pancreatic Cancer: ASCO Clinical Practice Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 36 (24 ) ,2545-2556 More Information

Barata, Pedro C; Mendiratta, Prateek; Heald, Brandie; Klek, Stefan; Grivas, Petros; Sohal, Davendra P S; Garcia, Jorge A (2018. ) Targeted Next-Generation Sequencing in Men with Metastatic Prostate Cancer: a Pilot Study.Targeted oncology, , 13 (4 ) ,495-500 More Information

Sohal, Davendra P S; Tullio, Katherine; Khorana, Alok A (2018. ) Do patients with pancreatic body or tail cancer benefit from adjuvant therapy?A cohort study.Surgical oncology, , 27 (2 ) ,245-250 More Information

Drilon, Alexander; Laetsch, Theodore W; Kummar, Shivaani; DuBois, Steven G; Lassen, Ulrik N; Demetri, George D; Nathenson, Michael; Doebele, Robert C; Farago, Anna F; Pappo, Alberto S; Turpin, Brian; Dowlati, Afshin; Brose, Marcia S; Mascarenhas, Leo; Federman, Noah; Berlin, Jordan; El-Deiry, Wafik S; Baik, Christina; Deeken, John; Boni, Valentina; Nagasubramanian, Ramamoorthy; Taylor, Matthew; Rudzinski, Erin R; Meric-Bernstam, Funda; Sohal, Davendra P S; Ma, Patrick C; Raez, Luis E; Hechtman, Jaclyn F; Benayed, Ryma; Ladanyi, Marc; Tuch, Brian B; Ebata, Kevin; Cruickshank, Scott; Ku, Nora C; Cox, Michael C; Hawkins, Douglas S; Hong, David S; Hyman, David M (2018. ) Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.The New England journal of medicine, , 378 (8 ) ,731-739 More Information

Sohal, Davendra P S (2018. ) Point: Weighing the Risks and Benefits of Neoadjuvant Therapy in Resectable Pancreatic Cancer. Early, Aggressive Neoadjuvant Therapy Is Appropriate in Selected Patients. Oncology (Williston Park, N.Y.), , 32 (1 ) ,39-41, 44

Sohal, Davendra P S; Kuderer, Nicole M; Shepherd, Frances A; Pabinger, Ingrid; Agnelli, Giancarlo; Liebman, Howard A; Meyer, Guy; Kalady, Matthew F; McCrae, Keith; Lyman, Gary H; Khorana, Alok A (2017. ) Clinical Predictors of Early Mortality in Colorectal Cancer Patients Undergoing Chemotherapy: Results From a Global Prospective Cohort Study.JNCI cancer spectrum, , 1 (1 ) ,pkx009 More Information

Dhir, Mashaal; Malhotra, Gautam K; Sohal, Davendra P S; Hein, Nicholas A; Smith, Lynette M; O'Reilly, Eileen M; Bahary, Nathan; Are, Chandrakanth (2017. ) Neoadjuvant treatment of pancreatic adenocarcinoma: a systematic review and meta-analysis of 5520 patients.World journal of surgical oncology, , 15 (1 ) ,183 More Information

Barata, P C; Koshkin, V S; Funchain, P; Sohal, D; Pritchard, A; Klek, S; Adamowicz, T; Gopalakrishnan, D; Garcia, J; Rini, B; Grivas, P (2017. ) Next-generation sequencing (NGS) of cell-free circulating tumor DNA and tumor tissue in patients with advanced urothelial cancer: a pilot assessment of concordance.Annals of oncology : official journal of the European Society for Medical Oncology, , 28 (10 ) ,2458-2463 More Information

Bhagat, Tushar D; Chen, Si; Bartenstein, Matthias; Barlowe, A Trevor; Von Ahrens, Dagny; Choudhary, Gaurav S; Tivnan, Patrick; Amin, Elianna; Marcondes, A Mario; Sanders, Mathijs A; Hoogenboezem, Remco M; Kambhampati, Suman; Ramachandra, Nandini; Mantzaris, Iaonnis; Sukrithan, Vineeth; Laurence, Remi; Lopez, Robert; Bhagat, Prafullla; Giricz, Orsi; Sohal, Davendra; Wickrema, Amittha; Yeung, Cecilia; Gritsman, Kira; Aplan, Peter; Hochedlinger, Konrad; Yu, Yiting; Pradhan, Kith; Zhang, Jinghang; Greally, John M; Mukherjee, Siddhartha; Pellagatti, Andrea; Boultwood, Jacqueline; Will, Britta; Steidl, Ulrich; Raaijmakers, Marc H G P; Deeg, H Joachim; Kharas, Michael G; Verma, Amit (2017. ) Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/?-Catenin Activation.Cancer research, , 77 (18 ) ,4846-4857 More Information

Sohal, Davendra P S (2017. ) Adjuvant and neoadjuvant therapy for resectable pancreatic adenocarcinoma.Chinese clinical oncology, , 6 (3 ) ,26 More Information

McNamara, Michael J; Adelstein, David J; Allende, Daniela S; Bodmann, Joanna W; Ives, Denise I; Murthy, Sudish C; Raymond, Daniel; Raja, Siva; Rodriguez, Cristina P; Sohal, Davendra; Stephans, Kevin L; Videtic, Gregory M M; Rybicki, Lisa A (2017. ) Persistent Dysphagia After Induction Chemotherapy in Patients with Esophageal Adenocarcinoma Predicts Poor Post-Operative Outcomes.Journal of gastrointestinal cancer, , 48 (2 ) ,181-189 More Information

Benson, Al B; D'Angelica, Michael I; Abbott, Daniel E; Abrams, Thomas A; Alberts, Steven R; Saenz, Daniel Anaya; Are, Chandrakanth; Brown, Daniel B; Chang, Daniel T; Covey, Anne M; Hawkins, William; Iyer, Renuka; Jacob, Rojymon; Karachristos, Andrea; Kelley, R Kate; Kim, Robin; Palta, Manisha; Park, James O; Sahai, Vaibhav; Schefter, Tracey; Schmidt, Carl; Sicklick, Jason K; Singh, Gagandeep; Sohal, Davendra; Stein, Stacey; Tian, G Gary; Vauthey, Jean-Nicolas; Venook, Alan P; Zhu, Andrew X; Hoffmann, Karin G; Darlow, Susan (2017. ) NCCN Guidelines Insights: Hepatobiliary Cancers, Version 1.2017.Journal of the National Comprehensive Cancer Network : JNCCN, , 15 (5 ) ,563-573 More Information

Sohal, Davendra P S; Mangu, Pamela B; Laheru, Daniel (2017. ) Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Summary.Journal of oncology practice, , 13 (4 ) ,261-264 More Information

Sohal, Davendra P S; Mangu, Pamela B; Laheru, Daniel; Khorana, Alok A (2017. ) Reply to A. Wang-Gillam et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 35 (6 ) ,690-691 More Information

Sohal, Davendra P S; Willingham, Field F; Falconi, Massimo; Raphael, Kara L; Crippa, Stefano (2017. ) Pancreatic Adenocarcinoma: Improving Prevention and Survivorship.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, , 37 ,301-310 More Information

Sohal, Davendra P S; Shrotriya, Shiva; Abazeed, Mohamed; Cruise, Michael; Khorana, Alok (2016. ) Molecular characteristics of biliary tract cancer.Critical reviews in oncology/hematology, , 107 ,111-118 More Information

Sohal, Davendra P S; Mangu, Pamela B; Khorana, Alok A; Shah, Manish A; Philip, Philip A; O'Reilly, Eileen M; Uronis, Hope E; Ramanathan, Ramesh K; Crane, Christopher H; Engebretson, Anitra; Ruggiero, Joseph T; Copur, Mehmet S; Lau, Michelle; Urba, Susan; Laheru, Daniel (2016. ) Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 34 (23 ) ,2784-96 More Information

McNamara, Michael J; Rybicki, Lisa A; Sohal, Davendra; Allende, Daniela S; Videtic, Gregory M M; Rodriguez, Cristina P; Stephans, Kevin L; Murthy, Sudish C; Raja, Siva; Raymond, Daniel; Ives, Denise I; Bodmann, Joanna W; Adelstein, David J (2016. ) The relationship between pathologic nodal disease and residual tumor viability after induction chemotherapy in patients with locally advanced esophageal adenocarcinoma receiving a tri-modality regimen.Journal of gastrointestinal oncology, , 7 (2 ) ,196-205 More Information

Edwin, Natasha Catherine; Khoury, Michael N; Sohal, Davendra; McCrae, Keith R; Ahluwalia, Manmeet S; Khorana, Alok A (2016. ) Recurrent venous thromboembolism in glioblastoma.Thrombosis research, , 137 ,184-188 More Information

Sohal, Davendra P S; Rini, Brian I; Khorana, Alok A; Dreicer, Robert; Abraham, Jame; Procop, Gary W; Saunthararajah, Yogen; Pennell, Nathan A; Stevenson, James P; Pelley, Robert; Estfan, Bassam; Shepard, Dale; Funchain, Pauline; Elson, Paul; Adelstein, David J; Bolwell, Brian J (2015. ) Prospective Clinical Study of Precision Oncology in Solid Tumors.Journal of the National Cancer Institute, , 108 (3 ) , More Information

Sohal, D P S; Rice, T W; Rybicki, L A; Rodriguez, C P; Videtic, G M M; Saxton, J P; Murthy, S C; Mason, D P; Phillips, B E; Tubbs, R R; Plesec, T; McNamara, M J; Ives, D I; Bodmann, J W; Adelstein, D J Gefitinib in definitive management of esophageal or gastroesophageal junction cancer: a retrospective analysis of two clinical trials.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, , 28 (6 ) ,547-51 More Information

Sohal, Davendra P S; Shrotriya, Shiva; Glass, Kate Tullio; Pelley, Robert J; McNamara, Michael J; Estfan, Bassam; Shapiro, Marc; Wey, Jane; Chalikonda, Sricharan; Morris-Stiff, Gareth; Walsh, R Matthew; Khorana, Alok A (2015. ) Predicting early mortality in resectable pancreatic adenocarcinoma: A cohort study.Cancer, , 121 (11 ) ,1779-84 More Information

McNamara, Michael J; Adelstein, David J; Bodmann, Joanna W; Greskovich, John F; Ives, Denise I; Mason, David P; Murthy, Sudish C; Rice, Thomas W; Saxton, Jerrold P; Sohal, Davendra; Stephans, Kevin; Rodriguez, Cristina P; Videtic, Gregory M M; Rybicki, Lisa A (2014. ) A phase II trial of induction epirubicin, oxaliplatin, and fluorouracil, followed by surgery and postoperative concurrent cisplatin and fluorouracil chemoradiotherapy in patients with locoregionally advanced adenocarcinoma of the esophagus and gastroesophageal junction.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, , 9 (10 ) ,1561-7 More Information

Sohal, Davendra P S; Walsh, R Matthew; Ramanathan, Ramesh K; Khorana, Alok A (2014. ) Pancreatic adenocarcinoma: treating a systemic disease with systemic therapy.Journal of the National Cancer Institute, , 106 (3 ) ,dju011 More Information

Sohal, D P S; Mykulowycz, K; Uehara, T; Teitelbaum, U R; Damjanov, N; Giantonio, B J; Carberry, M; Wissel, P; Jacobs-Small, M; O'Dwyer, P J; Sepulveda, A; Sun, W (2013. ) A phase II trial of gemcitabine, irinotecan and panitumumab in advanced cholangiocarcinoma.Annals of oncology : official journal of the European Society for Medical Oncology, , 24 (12 ) ,3061-5 More Information

Sohal, Davendra P S; Metz, James M; Sun, Weijing; Giantonio, Bruce J; Plastaras, John P; Ginsberg, Gregory; Kochman, Michael L; Teitelbaum, Ursina R; Harlacker, Kathleen; Heitjan, Daniel F; Feldman, Michael D; Drebin, Jeffrey A; O'Dwyer, Peter J (2013. ) Toxicity study of gemcitabine, oxaliplatin, and bevacizumab, followed by 5-fluorouracil, oxaliplatin, bevacizumab, and radiotherapy, in patients with locally advanced pancreatic cancer.Cancer chemotherapy and pharmacology, , 71 (6 ) ,1485-91 More Information

Nischal, Sangeeta; Bhattacharyya, Sanchari; Christopeit, Maximilian; Yu, Yiting; Zhou, Li; Bhagat, Tushar D; Sohal, Davendra; Will, Britta; Mo, Yongkai; Suzuki, Masako; Pardanani, Animesh; McDevitt, Michael; Maciejewski, Jaroslaw P; Melnick, Ari M; Greally, John M; Steidl, Ulrich; Moliterno, Alison; Verma, Amit (2013. ) Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.Cancer research, , 73 (3 ) ,1076-85 More Information

Sohal, Davendra P S; Sun, Weijing (2011. ) What is the reference cytotoxic regimen for advanced gastric cancer: standard versus optimal therapy?.Expert review of anticancer therapy, , 11 (12 ) ,1843-50 More Information

Moghanaki, Drew; Mick, Rosemarie; Furth, Emma Elizabeth; Sohal, Davendra; Salmon, Patricia M; Behbahani, Ali; Morgans, Alicia K; Miller, Seth M; Giantonio, Bruce J; Whittington, Richard W; Haller, Daniel G; Rosato, Ernest F; Plastaras, John P (2011. ) Resection status, age and nodal involvement determine survival among patients receiving adjuvant chemoradiotherapy in pancreatic adenocarcinoma. JOP : Journal of the pancreas, , 12 (5 ) ,438-44

Sun, Weijing; Sohal, Davendra; Haller, Daniel G; Mykulowycz, Kristine; Rosen, Mark; Soulen, Michael C; Caparro, Millie; Teitelbaum, Ursina R; Giantonio, Bruce; O'Dwyer, Peter J; Shaked, Abraham; Reddy, Rajender; Olthoff, Kim (2011. ) Phase 2 trial of bevacizumab, capecitabine, and oxaliplatin in treatment of advanced hepatocellular carcinoma.Cancer, , 117 (14 ) ,3187-92 More Information

Zhou, Li; Opalinska, Joanna; Sohal, Davendra; Yu, Yiting; Mo, Yongkai; Bhagat, Tushar; Abdel-Wahab, Omar; Fazzari, Melissa; Figueroa, Maria; Alencar, Cristina; Zhang, Jinghang; Kambhampati, Suman; Parmar, Simrit; Nischal, Sangeeta; Hueck, Christoph; Suzuki, Masako; Freidman, Ellen; Pellagatti, Andrea; Boultwood, Jacqueline; Steidl, Ulrich; Sauthararajah, Yogen; Yajnik, Vijay; McMahon, Christine; Gore, Steven D; Platanias, Leonidas C; Levine, Ross; Melnick, Ari; Wickrema, Amittha; Greally, John M; Verma, Amit (2011. ) Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.The Journal of biological chemistry, , 286 (28 ) ,25211-23 More Information

Sohal, Davendra P S; Sun, Weijing (2011. ) Hepatocellular carcinoma: prevention and therapy.Current oncology reports, , 13 (3 ) ,186-94 More Information

Alvarez, Hector; Opalinska, Joanna; Zhou, Li; Sohal, Davendra; Fazzari, Melissa J; Yu, Yiting; Montagna, Christina; Montgomery, Elizabeth A; Canto, Marcia; Dunbar, Kerry B; Wang, Jean; Roa, Juan Carlos; Mo, Yongkai; Bhagat, Tushar; Ramesh, K H; Cannizzaro, Linda; Mollenhauer, J; Thompson, Reid F; Suzuki, Masako; Meltzer, Stephen J; Meltzer, Stephen; Melnick, Ari; Greally, John M; Maitra, Anirban; Verma, Amit (2011. ) Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.PLoS genetics, , 7 (3 ) ,e1001356 More Information

Zhou, Li; McMahon, Christine; Bhagat, Tushar; Alencar, Cristina; Yu, Yiting; Fazzari, Melissa; Sohal, Davendra; Heuck, Christoph; Gundabolu, Krishna; Ng, Chun; Mo, Yongkai; Shen, Wa; Wickrema, Amittha; Kong, Guanghui; Friedman, Ellen; Sokol, Lubomir; Mantzaris, Ioannis; Mantzaris, Giannis; Pellagatti, Andrea; Boultwood, Jacqueline; Platanias, Leonidas C; Steidl, Ulrich; Yan, Lei; Yingling, Jonathan M; Lahn, Michael M; List, Alan; Bitzer, Markus; Verma, Amit (2011. ) Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase.Cancer research, , 71 (3 ) ,955-63 More Information

Garg, Nitin; Karagiorgos, Nikolaos; Pisimisis, George T; Sohal, Davendra P S; Longo, G Matthew; Johanning, Jason M; Lynch, Thomas G; Pipinos, Iraklis I (2009. ) Cerebral protection devices reduce periprocedural strokes during carotid angioplasty and stenting: a systematic review of the current literature.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, , 16 (4 ) ,412-27 More Information

Zhou, Li; Nguyen, Aaron N; Sohal, Davendra; Ying Ma, Jing; Pahanish, Perry; Gundabolu, Krishna; Hayman, Josh; Chubak, Adam; Mo, Yongkai; Bhagat, Tushar D; Das, Bhaskar; Kapoun, Ann M; Navas, Tony A; Parmar, Simrit; Kambhampati, Suman; Pellagatti, Andrea; Braunchweig, Ira; Zhang, Ying; Wickrema, Amittha; Medicherla, Satyanarayana; Boultwood, Jacqueline; Platanias, Leonidas C; Higgins, Linda S; List, Alan F; Bitzer, Markus; Verma, Amit (2008. ) Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.Blood, , 112 (8 ) ,3434-43 More Information

Sohal, Davendra; Yeatts, Andrew; Ye, Kenny; Pellagatti, Andrea; Zhou, Li; Pahanish, Perry; Mo, Yongkai; Bhagat, Tushar; Mariadason, John; Boultwood, Jacqueline; Melnick, Ari; Greally, John; Verma, Amit (2008. ) Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration.PloS one, , 3 (8 ) ,e2965 More Information

Dattilo, Philip B; Hailpern, Susan M; Fearon, Kerrie; Sohal, Davendra; Nordin, Charles (2008. ) Beta-blockers are associated with reduced risk of myocardial infarction after cocaine use.Annals of emergency medicine, , 51 (2 ) ,117-25 More Information

Isufi, Iris; Seetharam, Mahesh; Zhou, Li; Sohal, Davendra; Opalinska, Joanna; Pahanish, Perry; Verma, Amit (2007. ) Transforming growth factor-beta signaling in normal and malignant hematopoiesis.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, , 27 (7 ) ,543-52 More Information

Pishvaian, Michael J; Blais, Edik M; Brody, Jonathan R; Lyons, Emily; DeArbeloa, Patricia; Hendifar, Andrew; Mikhail, Sam; Chung, Vincent; Sahai, Vaibhav; Sohal, Davendra P S; Bellakbira, Sara; Thach, Dzung; Rahib, Lola; Madhavan, Subha; Matrisian, Lynn M; Petricoin, Emanuel F (2020. ) Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial.The Lancet. Oncology, , 21 (4 ) ,508-518 More Information

Bhagat, Tushar D; Von Ahrens, Dagny; Dawlaty, Meelad; Zou, Yiyu; Baddour, Joelle; Achreja, Abhinav; Zhao, Hongyun; Yang, Lifeng; Patel, Brijesh; Kwak, Changsoo; Choudhary, Gaurav S; Gordon-Mitchell, Shanisha; Aluri, Srinivas; Bhattacharyya, Sanchari; Sahu, Srabani; Bhagat, Prafulla; Yu, Yiting; Bartenstein, Matthias; Giricz, Orsi; Suzuki, Masako; Sohal, Davendra; Gupta, Sonal; Guerrero, Paola A; Batra, Surinder; Goggins, Michael; Steidl, Ulrich; Greally, John; Agarwal, Beamon; Pradhan, Kith; Banerjee, Debabrata; Nagrath, Deepak; Maitra, Anirban; Verma, Amit (2019. ) Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.eLife, , 8 , More Information

Pishvaian, Michael J; Blais, Edik M; Bender, R Joseph; Rao, Shruti; Boca, Simina M; Chung, Vincent; Hendifar, Andrew E; Mikhail, Sam; Sohal, Davendra P S; Pohlmann, Paula R; Moore, Kathleen N; He, Kai; Monk, Bradley J; Coleman, Robert L; Herzog, Thomas J; Halverson, David D; DeArbeloa, Patricia; Petricoin, Emanuel F; Madhavan, Subha (2019. ) A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients.JAMIA open, , 2 (4 ) ,505-515 More Information

Sohal D.P.S.;Sun W. (11-01-2012. ) Preoperative treatment of locally advanced rectal cancer .European Oncology and Haematology, , 8 (4 ) ,224-227

Sohal D.; Sun W. (11-01-2012. ) Preoperative treatment of locally advanced rectal cancer .European Oncology and Haematology, , 8 (4 ) ,224-227

Sohal D.;Pelley R. (06-20-2014. ) Recurrent and Metastatic Colorectal Cancer: Controversies, Consensus, and New Targets.Cancer Consult: Expertise for Clinical Practice, , 573-580 More Information

Pelley R.; Sohal D. (06-20-2014. ) Recurrent and Metastatic Colorectal Cancer: Controversies, Consensus, and New Targets.Cancer Consult: Expertise for Clinical Practice, , 573-580 More Information

McNamara M.;Rybicki L.;Sohal D.;Allende D.;Videtic G.;Rodriguez C.;Stephans K.;Murthy S.;Raja S.;Raymond D.;Ives D.;Bodmann J.;Adelstein D. (04-01-2016. ) The relationship between pathologic nodal disease and residual tumor viability after induction chemo.Journal of Gastrointestinal Oncology, , 7 (2 ) ,196-205 More Information

Adelstein D.; Allende D.; Bodmann J.; Ives D.; McNamara M.; Murthy S.; Raja S.; Raymond D.; Rodriguez C.; Rybicki L.; Sohal D.; Stephans K.; Videtic G. (04-01-2016. ) The relationship between pathologic nodal disease and residual tumor viability after induction chemo.Journal of Gastrointestinal Oncology, , 7 (2 ) ,196-205 More Information

Sadaps M.;Funchain P.;Mahdi H.;Grivas P.;Pritchard A.;Klek S.;Estfan B.;Abraham J.;Thomas Budd G.;Stevenson J.P.;Pennell N.A.;Khorana A.A.;Bolwell B.J.;Sohal D.P.S. (01-01-2018. ) Precision oncology in solid tumors: A longitudinal tertiary care center experience.JCO Precision Oncology, , 2 , More Information

Abraham J.; Bolwell B.J.; Estfan B.; Funchain P.; Grivas P.; Khorana A.A.; Klek S.; Mahdi H.; Pennell N.A.; Pritchard A.; Sadaps M.; Sohal D.P.S.; Stevenson J.P.; Thomas Budd G. (01-01-2018. ) Precision oncology in solid tumors: A longitudinal tertiary care center experience.JCO Precision Oncology, , 2 , More Information

Akras Z.;Bungo B.;Leach B.H.;Marquard J.;Ahluwalia M.;Carraway H.;Grivas P.;Sohal D.P.S.;Funchain P. (01-01-2019. ) Primer on hereditary cancer predisposition genes included within somatic next-generation sequencing .JCO Precision Oncology, , 3 , More Information

Ahluwalia M.; Akras Z.; Bungo B.; Carraway H.; Funchain P.; Grivas P.; Leach B.H.; Marquard J.; Sohal D.P.S. (01-01-2019. ) Primer on hereditary cancer predisposition genes included within somatic next-generation sequencing .JCO Precision Oncology, , 3 , More Information

Sadaps M.;Sohal D.P.S. (01-01-2019. ) Remarkable case of dual BRAF and MEK inhibition in cholangiocarcinoma.JCO Precision Oncology, , 3 , More Information

Sadaps M.; Sohal D.P.S. (01-01-2019. ) Remarkable case of dual BRAF and MEK inhibition in cholangiocarcinoma.JCO Precision Oncology, , 3 , More Information

Coelho Barata P.M.C.; Garcia J.A.; Gilligan T.; Grivas P.; Klek S.; Mendiratta P.; Ornstein M.; Rini B.I.; Sadaps M.; Sohal D. (10-01-2018. ) The clinical impact of targeted next generation sequencing (tNGS) in the treatment of metastatic pro.Annals of oncology : official journal of the European Society for Medical Oncology, , 29 ,viii295 More Information

Coelho Barata P.M.C.; Garcia J.A.; Gilligan T.; Grivas P.; Klek S.; Mendiratta P.; Ornstein M.; Rini B.I.; Sadaps M.; Sohal D. (10-01-2018. ) The clinical impact of targeted next generation sequencing (tNGS) in the treatment of metastatic pro.Annals of oncology : official journal of the European Society for Medical Oncology, , 29 ,viii295 More Information