Matia Solomon

Matia B Solomon

Assistant Professor of Department of Psychiatry & Behavioral Neuroscience

Edwards Center

4150 EDWARDS 1

A&S Psychology - 0376

Reading Campus
2120 East Galbraith Road
Cincinnati, Ohio 45237-0506

Professional Summary

The Solomon laboratory overall research efforts are directed towards understanding sex differences in the neurobiology of affective disorders and neurocognitive disorders including Alzheimer's disease.  For more information about our laboratory please visit: www.solomonlaboratory.com
 

Education

Doctoral Degree, Georgia State University 2006 (Behavioral Neuroscience)

Research and Practice Interests

sex differences in antidepressant efficacy

rodent models of depression and anxiety

neural regulation of depression and complex social behavior

role of gonadal hormones in depression and anxiety

epigenetic regulation of steroid receptors in depression and anxiety

Research Support

Investigators:Matia B. Solomon 07-01-2013 -07-01-2015 National Institutes of Health Effects of Chronic Stress on Female Depression Role:PI $200,000 Completed Type:Grant Level:National

Investigators:Matia B. Solomon 2014 -2016 Corcept Therapeutics Identifying Biomarkers for Depression: Focus on Lateral Habenula Role:PI $30,000 Completed

Investigators:Matia B. Solomon Faculty Development Council Two Week Multi Modality Course to Study Human Brain Function In Vivo at Harvard University Role:PI $3,600 Completed Level:University

Grant: #2014 Solomon - Biomarkers for Depression Investigators:Solomon, Matia 04-01-2014 -03-31-2016 Corcept Therapeutics Identifying Biomarkers for Depression: Focus on the Lateral Habenula Role:PI $30,000.00

Grant: #LIFE2016 Investigators:Solomon, Matia 09-01-2016 -08-31-2018 Local Initiative for Excellence (L.I.F.E.) Exploring the role of the oncogene Dek as a novel player in Alzheimer's disease Role:PI $50,000.00 Active Level:Private Non-Profit

Grant: #G-01323-01 Investigators:Solomon, Matia 09-01-2017 -08-31-2018 Lipedema Foundation A Mouse Model of Lipedema: Lower Body Subcutaneous Adipose Tissue Specific Estrogen Receptor KO Role:PI $8,493.00 Active Level:Private Non-Profit

Grant: #2019 Award Investigators:Solomon, Matia 11-01-2019 -10-31-2020 Local Initiative for Excellence (L.I.F.E.) Functional Significance of DEK in Alzheimer's Disease and Age-Related Dementias. Role:PI $50,000.00 Awarded Level:Private Non-Profit

Abbreviated Publications

Publications

Peer Reviewed Publications

Herman, J P; McKlveen, J M; Solomon, M B; Carvalho-Netto, E; Myers, B (2012. )Neural regulation of the stress response: glucocorticoid feedback mechanisms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], ,45 (4 ),292-8

Solomon, M B; Furay, A R; Jones, K; Packard, A E B; Packard, B A; Wulsin, A C; Herman, J P (2012. )Deletion of forebrain glucocorticoid receptors impairs neuroendocrine stress responses and induces depression-like behavior in males but not females.Neuroscience, ,203 ,135-43

Flak, Jonathan N; Jankord, Ryan; Solomon, Matia B; Krause, Eric G; Herman, James P (2011. )Opposing effects of chronic stress and weight restriction on cardiovascular, neuroendocrine and metabolic function.Physiology & behavior, ,104 (2 ),228-34

Carvalho-Netto, Eduardo F; Myers, Brent; Jones, Kenneth; Solomon, Matia B; Herman, James P (2011. )Sex differences in synaptic plasticity in stress-responsive brain regions following chronic variable stress.Physiology & behavior, ,104 (2 ),242-7

Solomon, Matia B; Sakai, Randall R; Woods, Stephen C; Foster, Michelle T (2011. )Differential effects of glucocorticoids on energy homeostasis in Syrian hamsters.American journal of physiology. Endocrinology and metabolism, ,301 (2 ),E307-16

Krause, Eric G; de Kloet, Annette D; Flak, Jonathan N; Smeltzer, Michael D; Solomon, Matia B; Evanson, Nathan K; Woods, Stephen C; Sakai, Randall R; Herman, James P (2011. )Hydration state controls stress responsiveness and social behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience, ,31 (14 ),5470-6

Castañeda, T R; Nogueiras, R; Müller, T D; Krishna, R; Grant, E; Jones, A; Ottaway, N; Ananthakrishnan, G; Pfluger, P T; Chaudhary, N; Solomon, M B; Woods, S C; Herman, J P; Tschöp, M H (2011. )Decreased glucose tolerance and plasma adiponectin:resistin ratio in a mouse model of post-traumatic stress disorder.Diabetologia, ,54 (4 ),900-9

Jankord, Ryan; Solomon, Matia B; Albertz, Jennifer; Flak, Jonathan N; Zhang, Rong; Herman, James P (2011. )Stress vulnerability during adolescent development in rats.Endocrinology, ,152 (2 ),629-38

Solomon, Matia B; Jankord, Ryan; Flak, Jonathan N; Herman, James P (2011. )Chronic stress, energy balance and adiposity in female rats.Physiology & behavior, ,102 (1 ),84-90

Ulrich-Lai, Yvonne M; Christiansen, Anne M; Ostrander, Michelle M; Jones, Amanda A; Jones, Kenneth R; Choi, Dennis C; Krause, Eric G; Evanson, Nathan K; Furay, Amy R; Davis, Jon F; Solomon, Matia B; de Kloet, Annette D; Tamashiro, Kellie L; Sakai, Randall R; Seeley, Randy J; Woods, Stephen C; Herman, James P (2010. )Pleasurable behaviors reduce stress via brain reward pathways.Proceedings of the National Academy of Sciences of the United States of America, ,107 (47 ),20529-34

Zhang, Rong; Jankord, Ryan; Flak, Jonathan N; Solomon, Matia B; D'Alessio, David A; Herman, James P (2010. )Role of glucocorticoids in tuning hindbrain stress integration.The Journal of neuroscience : the official journal of the Society for Neuroscience, ,30 (44 ),14907-14

Wulsin, Aynara C; Herman, James P; Solomon, Matia B (2010. )Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress.Psychoneuroendocrinology, ,35 (7 ),1100-12

Jankord, Ryan; Zhang, Rong; Flak, Jonathan N; Solomon, Matia B; Albertz, Jennifer; Herman, James P (2010. )Stress activation of IL-6 neurons in the hypothalamus.American journal of physiology. Regulatory, integrative and comparative physiology, ,299 (1 ),R343-51

Solomon, M B; Jones, K; Packard, B A; Herman, J P (2010. )The medial amygdala modulates body weight but not neuroendocrine responses to chronic stress.Journal of neuroendocrinology, ,22 (1 ),13-23

Solomon, Matia B; Karom, Mary C; Norvelle, Alisa; Markham, Chris A; Erwin, W Daniel; Huhman, Kim L (2009. )Gonadal hormones modulate the display of conditioned defeat in male Syrian hamsters.Hormones and behavior, ,56 (4 ),423-8

Solomon, Matia B; Herman, James P (2009. )Sex differences in psychopathology: of gonads, adrenals and mental illness.Physiology & behavior, ,97 (2 ),250-8

Solomon, Matia B; Karom, Mary C; Huhman, Kim L (2007. )Sex and estrous cycle differences in the display of conditioned defeat in Syrian hamsters.Hormones and behavior, ,52 (2 ),211-9

Solomon, Matia B; Foster, Michelle T; Bartness, Timothy J; Huhman, Kim L (2007. )Social defeat and footshock increase body mass and adiposity in male Syrian hamsters.American journal of physiology. Regulatory, integrative and comparative physiology, ,292 (1 ),R283-90

Foster, Michelle T; Solomon, Matia B; Huhman, Kim L; Bartness, Timothy J (2006. )Social defeat increases food intake, body mass, and adiposity in Syrian hamsters.American journal of physiology. Regulatory, integrative and comparative physiology, ,290 (5 ),R1284-93

Faruzzi, Alicia N; Solomon, Matia B; Demas, Gregory E; Huhman, Kim L (2005. )Gonadal hormones modulate the display of submissive behavior in socially defeated female Syrian hamsters.Hormones and behavior, ,47 (5 ),569-75

Huhman, Kim L; Solomon, Matia B; Janicki, Marcus; Harmon, Alvin C; Lin, Stacie M; Israel, Jeris E; Jasnow, Aaron M (2003. )Conditioned defeat in male and female Syrian hamsters. Hormones and behavior, ,44 (3 ),293-9

Flak, J.N., Solomon, M.B., Krause, E.G., & Herman, J.P. (2012. )Identification of chronic stress activated regions reveals a potential recruited circuit in rat brain .European Journal of Neuroscience, ,

Jasnow, A.M., Banks, M.C., Owens, E.C., & Huhman, K.L. (1999. )Differential effects of two corticotropin-releasing factor antagonists on conditioned defeat in male Syrian hamsters (Mesocricetus auratus). .Brain Research, ,846 (1 ),122 -128

Book Chapter

Young, E.A., Korszun, A., Figueiredo, H.F., Solomon, M.B., & Herman, J.P. (2007 )Sex differences in HPA axis Regulation. Sex Differences in brain: From Genes to Behavior .(pp. 95-108).Oxford

Solomon, M.B., & Herman, J.P. (2009 )Sex differences in HPA axis regulation: The role of gonadal hormones Hormones, Brain and Behavior 2nd Edition .(pp. 2291-2306).Academic Press

Presentations

Invited Presentations

Matia B. Solomon (2005. )Conditioned defeat in female and Syrian hamsters .University of California San Francisco, Department of Physiology.

Matia B. Solomon (2005. )Sex and estrous cycle differences in the display of conditioned defeat in Syrian hamsters .University of Cincinnati , Department of Psychiatry.

Matia B. Solomon (2007. )What can rodent models of social stress teach us about depression? .Morehouse School of Medicine, Neuroscience Institute Spring Seminar Series.

Matia B. Solomon (2007. )GPR30 (Membrane Bound Estrogen Receptor) and HPA axis Activation: What's the Connection? .Organization for Study of Sex Differences, Washington, DC.

Matia B. Solomon (2007. )Sex differences in HPA axis Regulation and Depression-Like Behavior in Forebrain Glucocorticoid Receptor Knockout Mice .Neurobiology of Stress Conference, Boulder Colorado.

Matia B. Solomon (2011. )Sex Differences in HPA axis Regulation and Depression-Like Behavior in Forebrain Glucocorticoid Receptor Knockout Mice .Department of Psychiatry Neuroscience Spring Seminar Series, Cincinnati Ohio.

Matia B. Solomon (06-2012. )Sex Differences in HPA axis Regulation and Depression-Like Behavior .Elizabeth Young New Investigator Seminar (Organization for Study of Sex Differences), Baltimore, MD.

Matia B. Solomon (11-2012. )Glucocorticoid Receptor Antagonists: Modulators of Neuroendocrine Stress Responses and Depression .Corcepts Therapeutics Inc, Half Moon Bay, CA.

Matia B. Solomon (10-05-2012. )Sex Differences in Central GR Signaling: HPA axis and Depression .Kent State University Department of Biological Sciences, Kent, Ohio.

Matia B. Solomon Inspirational Speaker for Underrepresented Minorities .McNair Scholars Program , University of Cincinnati . UC. .Level:University

Matia B. Solomon My Path from Humans to Rodents towards Understanding Human Psychopathology .Research Experience for Undergraduates in Complex Psychology, Psychology Department . UC. .Level:Department

Matia B. Solomon Neurobiology of Female Depression .Cincinnati Children’s Hospital Medical Center , K Scholar's Meeting. Other Institution. .

Matia B. Solomon Impact of Chronic Psychosocial Stress on Brain and Behavior .Medical Sciences Building, University of Cincinnati (Neuroscience Seminar Speaker). UC. .

Event Organized

Who's Who in Psychology Faculty Retreat

Who's Who in Psychology Faculty Retreat Other University of Cincinnati Level:Department

Honors and Awards

2005 American Neuroendocrine Society Travel Award

2007 Organization for Study of Sex Differences Young Investigator Travel Award

2008 Organization for Study of Sex Differences New Investigator Award Outstanding Research Presentation

2008 NMRI Midwest Conference National Institute of Diabetes, Digestive and Kidney Diseases Excellence In Research Award 2nd Place

2010 National Institutes of Health Postdoctoral Pathway to Independence Travel Award

2010 Stress Neurobiology Conference Travel Award

2012 Organization for Study of Sex Differences Young Investigator Travel Award

2012 Elizabeth Young New Investigator Award

Nominated to Represent UC as an Emerging Minority Faculty Scholar Status:Nomination

Service

(Diversity Committee )Member Type:Departmental Service Level:Department 08-15-2012

(Honor's Committee )Committee Member Type:Departmental Service Level:Department 08-15-2012

(Department Cohesion Committee )Type:Departmental Service Level:Department

Psychiatry and Behavioral Neuroscience (UC) (Center for Diabetes and Obesity Center (grant reviewer) )Type:Departmental Service Level:Department

(Isabel and Mary Neff Scholarship Committee )Type:University/College Service Level:College

(NSF Accountability and Advocacy Council )Type:University/College Service Level:University

Post Graduate Training and Education

2006-2011 Postdoctoral Research Fellow, Stress Neurobiology, University of Cincinnati, ,Cincinnati Ohio

2011-2012 Research Scientist, University of Cincinnati , ,Cincinnati, Ohio

Keywords

behavioral neuroscience, stress, sex differences, gonadal hormones, antidepressants, depression, anxiety, obesity

Professional Affiliation

06-01-2008: Organization for Study of Sex Differences

08-01-2000: Society for Neuroscience

Reviewer for Hormones and Behavior

Reviewer for Journal for Neuroscience

Reviewer for Proceedings for National Academy of Science

Reviewer for Physiology and Behavior

Courses Taught

Research Methods in Stress and Health Level:Undergraduate

Faculty Development Activities

12-05-2012 -12-05-2012 Google Tips and Tricks Type:Workshop

Contact Information

Academic - Reading Campus
2120 East Galbraith Road
Cincinnati  Ohio, 45237-0506
Phone: 513-558-3025
Fax: 513-297-0966
solomomb@ucmail.uc.edu