Vinita Takiar

Vinita Takiar, MD

Professor - Adj (FC)

UC Barrett Cancer Center
3151 Bellevue Avenue, ML 0757
Cincinnati, Ohio 45219
Phone 513-584-5668
Fax 513-584-4007
Email takiarva@ucmail.uc.edu

Education

Bachelor's Degree: The Johns Hopkins University Baltimore, MD, 2003 (Biophysics and English)

PhD: Yale University New Haven, CT, 2010 (Cellular and Molecular Physiology)

Medical Degree: Yale University School of Medicine New Haven, CT, 2010

Residency: University of Texas, MD Anderson Cancer Center Houston, TX, 2015 (Radiation Oncology)

Certifications

American Board of Radiology (Radiation Oncology) (Certification Date: 05-17-2016 )

Research and Practice Interests

Radiation Oncology
Radiation Resistance
Head and Neck Cancer (including but not limited to):

  • Ear/Neck
  • Eye/Nose
  • Oral Cavity
  • Hypophaynx
  • Larynx
  • Oropharynx
  • Nasopharynx
  • Major Salivary Gland
  • Nasal Cavity
  • Sinus
  • Thyroid
  • Trachea
  • Skin of Head and Neck
  • Unknown Primary of Head and Neck
  • Head and Neck Metastases

Research Support

Grant: #Contract No. 475524 Investigators:Ionascu, Traian; Lamba, Michael; Takiar, Vinita; Vatner, Ralph 08-02-2019 -07-31-2020 Department of Energy Evaluating Equivalence of Cellular Response to X-ray and Gamma Irradiation of Varying Energies Role:Collaborator $53,489.25 Active Level:Federal

Grant: #R01CA255331 Investigators:Phoenix, Timothy; Sasaki, Atsuo; Sengupta, Soma; Takiar, Vinita 07-07-2021 -06-30-2026 National Cancer Institute Therapeutic resistance and aggressive malignancy in glioblastomas: the contribution of GTP metabolism through regulation by IMPDH2 Role:Collaborator 413481.00 Awarded Level:Federal

Grant: #T32CA117846 Investigators:Price, Carolyn; Takiar, Vinita; Waltz, Susan 09-01-2018 -08-31-2023 National Cancer Institute Pathways to Cancer Therapeutics Role:Collaborator 1918377.00 Active Level:Federal

Grant: #T32CA298951 Investigators:Takiar, Vinita; Waltz, Susan 04-01-2025 -03-31-2030 National Cancer Institute Training Program in Basic and Translational Oncology Role:Collaborator 0.00 Hold Level:Federal

Publications

Peer Reviewed Publications

Takiar, Vinita; Ma, Dominic; Garden, Adam S; Li, Jing; Rosenthal, David I; Beadle, Beth M; Frank, Steven J; Fuller, Clifton D; Gunn, Gary B; Morrison, William H; Hutcheson, Kate; El-Naggar, Adel K; Gold, Kathryn A; Kupferman, Michael E; Phan, Jack  (2015). Disease control and toxicity outcomes for T4 carcinoma of the nasopharynx treated with intensity-modulated radiotherapy. Head & neckMore Information

Takiar, Vinita; Voong, K Ranh; Gombos, Dan S; Mourtada, Firas; Rechner, Laura A; Lawyer, Ann A; Morrison, William H; Garden, Adam S; Beadle, Beth MA choice of radionuclide: Comparative outcomes and toxicity of ruthenium-106 and iodine-125 in the definitive treatment of uveal melanoma. Practical radiation oncology, 5 (3) , e169-76More Information

Tao, Randa; Ma, Dominic; Takiar, Vinita; Frank, Steven J; Fuller, Clifton D; Gunn, G Brandon; Beadle, Beth M; Morrison, William H; Rosenthal, David I; Edson, Mark A; Esmaeli, Bita; Kupferman, Michael E; Hanna, Ehab Y; Garden, Adam S; Phan, Jack  (2015). Orbital carcinomas treated with adjuvant intensity-modulated radiation therapy. Head & neckMore Information

Takiar, Vinita; Gombos, Dan S; Mourtada, Firas; Rechner, Laura A; Lawyer, Ann A; Morrison, William H; Garden, Adam S; Beadle, Beth MDisease control and toxicity outcomes using ruthenium eye plaque brachytherapy in the treatment of uveal melanoma. Practical radiation oncology, 4 (4) , e189-94More Information

Hoffman, Karen E; Voong, K Ranh; Pugh, Thomas J; Skinner, Heath; Levy, Lawrence B; Takiar, Vinita; Choi, Seungtaek; Du, Weiliang; Frank, Steven J; Johnson, Jennifer; Kanke, James; Kudchadker, Rajat J; Lee, Andrew K; Mahmood, Usama; McGuire, Sean E; Kuban, Deborah A  (2014). Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial. International journal of radiation oncology, biology, physics, 88 (5) , 1074-84More Information

Takiar, Vinita; Pugh, Thomas J; Swanson, David; Kudchadker, Rajat J; Bruno, Teresa L; McAvoy, Sarah; Mahmood, Usama; Frank, Steven JMRI-based sector analysis enhances prostate palladium-103 brachytherapy quality assurance in a phase II prospective trial of men with intermediate-risk localized prostate cancer. Brachytherapy, 13 (1) , 68-74More Information

Takiar, Vinita; Akay, Catherine L; Stauder, Michael C; Tereffe, Welela; Alvarez, Ricardo H; Hoffman, Karen E; Perkins, George H; Strom, Eric A; Buchholz, Thomas A; Ueno, Naoto T; Babiera, Gildy; Woodward, Wendy A  (2014). Predictors of durable no evidence of disease status in de novo metastatic inflammatory breast cancer patients treated with neoadjuvant chemotherapy and post-mastectomy radiation. SpringerPlus, 3, 166More Information

Takiar, Vinita; Fontanilla, Hiral P; Eifel, Patricia J; Jhingran, Anuja; Kelly, Patrick; Iyer, Revathy B; Levenback, Charles F; Zhang, Yongbin; Dong, Lei; Klopp, Ann  (2013). Anatomic distribution of fluorodeoxyglucose-avid para-aortic lymph nodes in patients with cervical cancer. International journal of radiation oncology, biology, physics, 85 (4) , 1045-50More Information

Takiar, Vinita; Strom, Eric A; Baumann, Donald P; Meric-Bernstam, Funda; Alvarez, Ricardo H; Gonzalez-Angulo, Ana M  (2013). Locoregional interaction of ixabepilone (ixempra) after breast cancer radiation. The oncologist, 18 (3) , 265-70More Information

Fontanilla, Hiral P; Klopp, Ann H; Lindberg, Mary E; Jhingran, Anuja; Kelly, Patrick; Takiar, Vinita; Iyer, Revathy B; Levenback, Charles F; Zhang, Yongbin; Dong, Lei; Eifel, Patricia JAnatomic distribution of [(18)F] fluorodeoxyglucose-avid lymph nodes in patients with cervical cancer. Practical radiation oncology, 3 (1) , 45-53More Information

Takiar, Vinita; Mistry, Kavita; Carmosino, Monica; Schaeren-Wiemers, Nicole; Caplan, Michael J  (2012). VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis. American journal of physiology. Cell physiology, 303 (8) , C862-71More Information

Lee, Daniel A; Bedont, Joseph L; Pak, Thomas; Wang, Hong; Song, Juan; Miranda-Angulo, Ana; Takiar, Vani; Charubhumi, Vanessa; Balordi, Francesca; Takebayashi, Hirohide; Aja, Susan; Ford, Eric; Fishell, Gordon; Blackshaw, Seth  (2012). Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche. Nature neuroscience, 15 (5) , 700-2More Information

Takiar, Vinita; Caplan, Michael J  (2011). Polycystic kidney disease: pathogenesis and potential therapies. Biochimica et biophysica acta, 1812 (10) , 1337-43More Information

Takiar, Vinita; Nishio, Saori; Seo-Mayer, Patricia; King, J Darwin; Li, Hui; Zhang, Li; Karihaloo, Anil; Hallows, Kenneth R; Somlo, Stefan; Caplan, Michael J  (2011). Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis. Proceedings of the National Academy of Sciences of the United States of America, 108 (6) , 2462-7More Information

Takiar, Vinita; Caplan, Michael J  (2010). Telling kidneys to cease and decyst. Nature medicine, 16 (7) , 751-2More Information

Fuh, Katherine C; Meneshian, Avedis; Patel, Chandrahas B; Takiar, Vinita; Bulkley, Gregory B  (2002). Signal transduction by reactive oxygen species: alternative paradigms for signaling specificity. Surgery, 131 (6) , 601-12

Forster, Neil; Warnick, Ronald; Takiar, Vinita; Pater, Luke; Breneman, John  (2018). Debulking surgery of pituitary adenoma as a strategy to facilitate definitive stereotactic radiosurgery. Journal of neuro-oncology, 138 (2) , 335-340More Information

Wise-Draper, Trisha; Sendilnathan, Arun; Palackdharry, Sarah; Pease, Nicholas; Qualtieri, Julianne; Butler, Randall; Sadraei, Nooshin Hashemi; Morris, John C; Patil, Yash; Wilson, Keith; Mark, Jonathan; Casper, Keith; Takiar, Vinita; Lane, Adam; Privette Vinnedge, Lisa  (2018). Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma. Translational oncology, 11 (1) , 168-174More Information

Tuttle, Traci R; Takiar, Vinita; Kumar, Bhavna; Kumar, Pawan; Ben-Jonathan, Nira  (2017). Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells. Cancer letters, 389, 33-40More Information

Takiar, V; Ip, C K M; Gao, M; Mills, G B; Cheung, L W T  (2017). Neomorphic mutations create therapeutic challenges in cancer. Oncogene, 36 (12) , 1607-1618More Information

Freese, Christopher; Takiar, Vinita; Fouladi, Maryam; DeWire, Mariko; Breneman, John; Pater, LukeRadiation and subsequent reirradiation outcomes in the treatment of diffuse intrinsic pontine glioma and a systematic review of the reirradiation literature. Practical radiation oncology, 7 (2) , 86-92More Information

Phan, Jack; Sio, Terence T; Nguyen, Theresa P; Takiar, Vinita; Gunn, G Brandon; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Morrison, William H; Beadle, Beth; Ma, Dominic; Zafereo, Mark E; Hutcheson, Kate A; Kupferman, Michael E; William, William N; Frank, Steven J  (2016). Reirradiation of Head and Neck Cancers With Proton Therapy: Outcomes and Analyses. International journal of radiation oncology, biology, physics, 96 (1) , 30-41More Information

Damast, Shari; Takiar, Vinita; McCarthy, Shirley; Higgins, Susan A  (2016). Treatment of early stage vaginal cancer with EBRT and MRI-based intracavitary brachytherapy: A retrospective case review. Gynecologic oncology reports, 17, 89-92More Information

Takiar, Vinita; Garden, Adam S; Ma, Dominic; Morrison, William H; Edson, Mark; Zafereo, Mark E; Gunn, Gary B; Fuller, Clifton D; Beadle, Beth; Frank, Steven J; William, William N; Kies, Merrill; El-Naggar, Adel K; Weber, Randal; Rosenthal, David I; Phan, Jack  (2016). Reirradiation of Head and Neck Cancers With Intensity Modulated Radiation Therapy: Outcomes and Analyses. International journal of radiation oncology, biology, physics, 95 (4) , 1117-31More Information

Mitra, Shreya; Federico, Lorenzo; Zhao, Wei; Dennison, Jennifer; Sarkar, Tapasree Roy; Zhang, Fan; Takiar, Vinita; Cheng, Kwai W; Mani, Sendurai; Lee, Ju Seog; Mills, Gordon B  (2016). Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT. Oncotarget, 7 (26) , 40252-40265More Information

Tang, Alice L; Miller, Adam; Hauff, Samantha; Myer, Charles M; Takiar, Vinita; Howell, Rebecca J; Mark, Jonathan R  (2018). Maternity and paternity leave in otolaryngology residency training in the United States. The LaryngoscopeMore Information

Haque, Sulsal; Karivedu, Vidhya; Riaz, Muhammed K; Choi, David; Roof, Logan; Hassan, Sarah Z; Zhu, Zheng; Jandarov, Roman; Takiar, Vinita; Tang, Alice; Wise-Draper, Trisha  (2019). High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma. Oral oncology, 88, 9-15More Information

Epperson, Madison; Gouveia, Christopher J; Tabangin, Meredith E; Takiar, Vinita; Howell, Rebecca; Altaye, Mekibib; Ishman, Stacey L; Tang, Alice L  (2019). Female Representation in Otolaryngology Leadership Roles. The LaryngoscopeMore Information

Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M  (2019). Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer. CancerMore Information

Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E  (2020). MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatmentMore Information

Havard, Molly; Esslinger, Hope; Mierzwa, Michelle; Kharofa, Jordan; Takiar, Vinita  (2020). Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis. The LaryngoscopeMore Information

Venkatraman, Anumitha; Kaval, Farah; Takiar, Vinita  (2020). Body Mass Index and Age Affect Maximum Mouth Opening in a Contemporary American Population. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial SurgeonsMore Information

Kreinbrink, Paul J; Lewis, Luke M; Redmond, Kevin P; Takiar, Vinita  (2022). Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence. Current treatment options in oncology, 23 (3) , 295-310More Information

Korns, Julianna; Liu, Xiaoqi; Takiar, Vinita  (2022). A review of Plks: Thinking outside the (polo) box. Molecular carcinogenesis, 61 (2) , 254-263More Information

Dubey, Poornima; Sertorio, Mathieu; Takiar, Vinita  (2022). Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy. Cancers, 14 (3) More Information

Lewis, Luke; Kreinbrink, Paul; Richardson, Max; Westerfield, Morgan; Doberstein, Madeline; Zhang, Yongbin; Redmond, Kevin; Takiar, Vinita  (2021). Intensity Modulated Proton Therapy Better Spares Non-Adjacent Organs and Reduces the Risk of Secondary Malignant Neoplasms in the Treatment of Sinonasal Cancers. Medical dosimetry : official journal of the American Association of Medical DosimetristsMore Information

Hernandez Brandi, Marianna; Howell, Rebecca; Power, Amelia; Tabangin, Meredith; Altaye, Mekibib; Zender, Chad A; Takiar, Vinita; Tang, Alice L  (2021). Trends in Number of Women Speakers at the American Head and Neck Society Meetings, 2007-2019. JAMA otolaryngology-- head & neck surgery, 147 (12) , 1053-1058More Information

Luginbuhl, Adam; Calder, Alyssa; Kutler, David; Zender, Chad; Wise-Draper, Trisha; Patel, Jena; Cheng, Michael; Karivedu, Vidhya; Zhan, Tingting; Parashar, Bhupesh; Gulati, Shuchi; Yao, Min; Lavertu, Pierre; Takiar, Vinita; Tang, Alice; Johnson, Jennifer; Keane, William; Curry, Joseph; Cognetti, David; Bar-Ad, Voichita  (2021). Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer. Frontiers in oncology, 11, 786216More Information

Kreinbrink, Paul J; Mierzwa, Michelle L; Huth, Brad; Redmond, Kevin P; Wise-Draper, Trisha M; Casper, Keith; Li, Junan; Takiar, Vinita  (2021). Adjuvant radiation and cetuximab improves local control in head and neck cutaneous squamous cell carcinoma: Phase II study. Head & neck, 43 (11) , 3408-3416More Information

von Allmen, Douglas; Tang, Alice; Takiar, Vinita; Zender, Chad; Romeo, Stephen; Masch, Jessica; Casper, Keith; Patil, Yash; Wilson, Keith; Khosla, Siddarth; Niu, Liang; Altaye, Mekibib; Tabangin, Meredith; Howell, Rebecca J  (2021). Modified Head and Neck Swallow Scale: Using EORTC-QLQ-H&N35 to Predict Overall Survival. The Laryngoscope, 131 (11) , 2478-2482More Information

Frankart, Andrew J; Takiar, Vinita  (2021). In Reply to Laurent et al. International journal of radiation oncology, biology, physics, 111 (2) , 584More Information

Sharma, Anish; Tang, Alice L; Takiar, Vinita; Wise-Draper, Trisha M; Langevin, Scott M  (2021). Human Papillomavirus and Survival of Sinonasal Squamous Cell Carcinoma Patients: A Systematic Review and Meta-Analysis. Cancers, 13 (15) More Information

Leddon, Jennifer L; Chirra, Martina; Frankart, Andrew J; Agrawal, Arushi; Roof, Logan; Trotier, Danny; Shaikh, Hira; Stone, Timothy; Jandarov, Roman; Takiar, Vinita; Wise-Draper, Trisha M  (2021). Hypothyroidism in Head and Neck Squamous Cell Carcinoma Patients Receiving Radiotherapy With or Without Immune Checkpoint Inhibitors. The Laryngoscope, 131 (7) , E2413-E2419More Information

Takiar, Vinita  (2021). In Reference to The Psychological Impact of Head and Neck Cancer in Pain Perception. The Laryngoscope, 131 (6) , E1911More Information

Kreinbrink, P J; Li, J; Parajuli, S; Wise-Draper, T M; Choi, D L; Tang, A L; Takiar, V  (2021). Pre-treatment absolute lymphocyte count predicts for improved survival in human papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma. Oral oncology, 116, 105245More Information

Wicker, Christina A; Hunt, Brian G; Krishnan, Sunil; Aziz, Kathryn; Parajuli, Shobha; Palackdharry, Sarah; Elaban, William R; Wise-Draper, Trisha M; Mills, Gordon B; Waltz, Susan E; Takiar, Vinita  (2021). Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models. Cancer letters, 502, 180-188More Information

Frankart, Andrew J; Criss, Benjamin E; Dillehay McKillip, Kelsey; Wise-Draper, Trisha; Takiar, Vinita; Kharofa, Jordan  (2021). Assessing the Reliability and Positive Predictive Value of p16 as a Surrogate for Human Papillomavirus-Mediated E6/7 mRNA Expression in Squamous Cell Carcinoma of the Anal Canal. Diseases of the colon and rectum, 64 (4) , 459-465More Information

Frankart, Andrew J; Frankart, Michael J; Cervenka, Brian; Tang, Alice L; Krishnan, Deepak G; Takiar, Vinita  (2021). Osteoradionecrosis: Exposing the Evidence Not the Bone. International journal of radiation oncology, biology, physics, 109 (5) , 1206-1218More Information

Wilke, Christopher; Takiar, Vinita; Wang, He; Moreno, Amy C; Tung, Shih-Ming Samuel; Quinlan-Davidson, Sean R; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Reddy, Jay P; Morrison, William H; Wang, Congjun; Zhao, George; Hutcheson, Katherine A; Phan, Jack  (2021). Defining the dose-volume criteria for laryngeal sparing in locally advanced oropharyngeal cancer utilizing split-field IMRT, whole-field IMRT and VMAT. Journal of applied clinical medical physics, 22 (1) , 37-44More Information

Wicker, Christina A; Takiar, Vinita; Suganya, Rangaswamy; Arnold, Susanne M; Brill, Yolanda M; Chen, Li; Horbinski, Craig M; Napier, Dana; Valentino, Joseph; Kudrimoti, Mahesh R; Yu, Guoqiang; Izumi, Tadahide  (2020). Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients. Oral oncology, 111, 104949More Information

Lewis, Luke M; Tang, Alice L; Wise-Draper, Trisha M; Myers, Kasiani C; Greenberger, Joel S; Takiar, Vinita  (2020). Successful use of a therapeutic trial of graduated volume and dose escalation for postoperative head and neck radiotherapy in a Fanconi anemia patient. Head & neck, 42 (10) , E16-E22More Information

Khanna, Suchin; Palackdharry, Sarah; Roof, Logan; Wicker, Christina A; Mark, Jonathan; Zhu, Zheng; Jandorav, Roman; Molinolo, Alfredo; Takiar, Vinita; Wise-Draper, Trisha M  (2020). Determining the molecular landscape and impact on prognosis in HPV-associated head and neck cancer. Cancers of the head & neck, 5, 11More Information

Moreno, Amy C; Wilke, Christopher; Wang, He; Tung, Shi-Ming Samuel; Pollard, Courtney; Garden, Adam S; Morrison, William H; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Reddy, Jay P; Shah, Shalin J; Frank, Steven J; Takiar, Vinita; Phan, Jack  (2019). Optimizing laryngeal sparing with intensity modulated radiotherapy or volumetric modulated arc therapy for unilateral tonsil cancer. Physics and imaging in radiation oncology, 10, 29-34More Information

Takiar, Vinita; Phan, Jack  (2016). In Reply to Mansha. International journal of radiation oncology, biology, physics, 96 (3) , 709More Information

Frankart, Andrew J; Abana, Chike O; Geier, Natalie; Bahig, Houda; Manzar, Gohar Shahwar; Garden, Adam S; Phan, Jack; Takiar, Vinita  (2022). Long-term Locoregional Control With Unilateral Radiation for AJCC-7 T1-2N2b Tonsillar Cancer. American journal of clinical oncology, 45 (10) , 422-426More Information

Nelson, Bailey; Takiar, Vinita  (2022). Low Risk, High Risk: Adjuvant Therapy in Resected p16+ Oropharyngeal Cancer with ?5 Positive Ipsilateral Lymph Nodes. International journal of radiation oncology, biology, physics, 114 (1) , 10-11More Information

Leddon, Jennifer L; Gulati, Shuchi; Haque, Sulsal; Allen, Casey; Palackdharry, Sarah; Mathews, Maria; Kurtzweil, Nicky; Riaz, Muhammed Kashif; Takiar, Vinita; Nagasaka, Misako; Patil, Yash; Zender, Chad; Tang, Alice; Cervenka, Brian; McGrath, Julie; Korn, W Michael; Hinrichs, Benjamin H; Jandarov, Roman; Harun, Nusrat; Sukari, Ammar; Wise-Draper, Trisha M  (2022). Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck. Clinical cancer research : an official journal of the American Association for Cancer Research, 28 (16) , 3464-3472More Information

Thompson, Samuel; Lewis, Luke; Takiar, Vinita  (2022). Hospital Price Transparency Rule Exposes Muddied Costs for Head and Neck Radiotherapy in One State. American journal of clinical oncology, 45 (6) , 268-272More Information

Wise-Draper, Trisha M; Gulati, Shuchi; Palackdharry, Sarah; Hinrichs, Benjamin H; Worden, Francis P; Old, Matthew O; Dunlap, Neal E; Kaczmar, John M; Patil, Yash; Riaz, Muhammed Kashif; Tang, Alice; Mark, Jonathan; Zender, Chad; Gillenwater, Ann M; Bell, Diana; Kurtzweil, Nicky; Mathews, Maria; Allen, Casey L; Mierzwa, Michelle L; Casper, Keith; Jandarov, Roman; Medvedovic, Mario; Lee, J Jack; Harun, Nusrat; Takiar, Vinita; Gillison, Maura  (2022). Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 28 (7) , 1345-1352More Information

Frankart, Andrew J; Sadraei, Nooshin Hashemi; Huth, Brad; Redmond, Kevin P; Barrett, William L; Kurtzweil, Nicky; Riaz, Muhammad K; Wise-Draper, Trisha; Rodriguez, Cristina P; Adelstein, David J; Takiar, Vinita  (2022). A phase I/II trial of concurrent immunotherapy with chemoradiation in locally advanced larynx cancer. Laryngoscope investigative otolaryngology, 7 (2) , 437-443More Information

Carsuzaa, Florent; Lapeyre, Michel; Gregoire, Vincent; Maingon, Philippe; Beddok, Arnaud; Marcy, Pierre-Yves; Salleron, Julia; Coutte, Alexandre; Racadot, Severine; Pointreau, Yoann; Graff, Pierre; Beadle, Beth; Benezery, Karen; Biau, Julian; Calugaru, Valentin; Castelli, Joel; Chua, Melvin; Di Rito, Alessia; Dore, Melanie; Ghadjar, Pirus; Huguet, Florence; Jardel, Pauline; Johansen, Jorgen; Kimple, Randall; Krengli, Marco; Laskar, Sarbani; Mcdowell, Lachlan; Nichols, Anthony; Tribius, Silke; Valduvieco, Izaskun; Hu, Chaosu; Liem, Xavier; Moya-Plana, Antoine; D'onofrio, Ida; Parvathaneni, Upendra; Takiar, Vinita; Orlandi, Ester; Psyrri, Amanda; Shenouda, George; Sher, David; Steuer, Conor; Shan Sun, Xu; Tao, Yungan; Thomson, David; Tsai, Mu-Hung; Vulquin, Noemie; Gorphe, Philippe; Mehanna, Hisham; Yom, Sue S; Bourhis, Jean; Thariat, Juliette  (2021). Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 160, 140-147More Information

Carsuzaa, Florent; Lapeyre, Michel; Gregoire, Vincent; Maingon, Philippe; Beddok, Arnaud; Marcy, Pierre-Yves; Salleron, Julia; Coutte, Alexandre; Racadot, Severine; Pointreau, Yoann; Graff, Pierre; Beadle, Beth; Benezery, Karen; Biau, Julian; Calugaru, Valentin; Castelli, Joel; Chua, Melvin; Di Rito, Alessia; Dore, Melanie; Ghadjar, Pirus; Huguet, Florence; Jardel, Pauline; Johansen, Jorgen; Kimple, Randall; Krengli, Marco; Laskar, Sarbani; Mcdowell, Lachlan; Nichols, Anthony; Tribius, Silke; Valduvieco, Izaskun; Hu, Chaosu; Liem, Xavier; Moya-Plana, Antoine; D'onofrio, Ida; Parvathaneni, Upendra; Takiar, Vinita; Orlandi, Ester; Psyrri, Amanda; Shenouda, George; Sher, David; Steuer, Conor; Shan Sun, Xu; Tao, Yungan; Thomson, David; Tsai, Mu-Hung; Vulquin, Noemie; Gorphe, Philippe; Mehanna, Hisham; Yom, Sue S; Bourhis, Jean; Thariat, Juliette  (2021). Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 160, 140-147More Information

Carsuzaa, Florent; Lapeyre, Michel; Gregoire, Vincent; Maingon, Philippe; Beddok, Arnaud; Marcy, Pierre-Yves; Salleron, Julia; Coutte, Alexandre; Racadot, Severine; Pointreau, Yoann; Graff, Pierre; Beadle, Beth; Benezery, Karen; Biau, Julian; Calugaru, Valentin; Castelli, Joel; Chua, Melvin; Di Rito, Alessia; Dore, Melanie; Ghadjar, Pirus; Huguet, Florence; Jardel, Pauline; Johansen, Jorgen; Kimple, Randall; Krengli, Marco; Laskar, Sarbani; Mcdowell, Lachlan; Nichols, Anthony; Tribius, Silke; Valduvieco, Izaskun; Hu, Chaosu; Liem, Xavier; Moya-Plana, Antoine; D'onofrio, Ida; Parvathaneni, Upendra; Takiar, Vinita; Orlandi, Ester; Psyrri, Amanda; Shenouda, George; Sher, David; Steuer, Conor; Shan Sun, Xu; Tao, Yungan; Thomson, David; Tsai, Mu-Hung; Vulquin, Noemie; Gorphe, Philippe; Mehanna, Hisham; Yom, Sue S; Bourhis, Jean; Thariat, Juliette  (2021). Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 160, 140-147More Information

Wang, He; Wang, Congjun; Tung, Samuel; Dimmitt, Andrew Wilson; Wong, Pei Fong; Edson, Mark A; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Takiar, Vinita; Wang, Xin A; Luo, Dershan; Yang, James N; Wong, Jennifer; Phan, Jack  (2016). Improved setup and positioning accuracy using a three-point customized cushion/mask/bite-block immobilization system for stereotactic reirradiation of head and neck cancer. Journal of applied clinical medical physics, 17 (3) , 180-189More Information

Edson, Mark A; Garden, Adam S; Takiar, Vinita; Glisson, Bonnie S; Fuller, Clifton D; Gunn, Gary B; Beadle, Beth M; Morrison, William H; Frank, Steven J; Shah, Shalin J; Tao, Randa; William, William N; Weber, Randal S; Rosenthal, David I; Phan, Jack  (2016). Outcomes for hypopharyngeal carcinoma treated with organ-preservation therapy. Head & neck, 38 Suppl 1, E2091-9More Information

Bonomi, Marcelo; Blakaj, Dukagjin M; Kabarriti, Rafi; Colvett, Kyle; Takiar, Vinita; Biagioli, Matthew; Bar-Ad, Voichita; Goyal, Sharad; Muzyka, Brian; Niermann, Kenneth; Abrouk, Nacer; Oronsky, Bryan; Reid, Tony; Caroen, Scott; Sonis, Stephen; Sher, David J  (2023). PREVLAR: Phase 2a Randomized Trial to Assess the Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Head and Neck Chemoradiotherapy. International journal of radiation oncology, biology, physics, 116 (3) , 551-559More Information

Gulati, Shuchi; Crist, McKenzie; Riaz, Muhammed Kashif; Takiar, Vinita; Lehn, Maria; Monroe, Ilaina; Palackdharry, Sarah; Kurtzweil, Nicky; Jandarov, Roman; Harun, Nusrat; Wise-Draper, Trisha M  (2023). Durvalumab plus Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-label, Nonrandomized, Phase II Clinical Trial. Clinical cancer research : an official journal of the American Association for Cancer Research, 29 (10) , 1906-1915More Information

Peterson, Joseph R; Cole, John A; Pfeiffer, John R; Norris, Gregory H; Zhang, Yuhan; Lopez-Ramos, Dorys; Pandey, Tushar; Biancalana, Matthew; Esslinger, Hope R; Antony, Anuja K; Takiar, Vinita  (2023). Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer. Breast cancer research : BCR, 25 (1) , 54More Information

Medek, Sara; Correa, Zelia M; Huth, Brad; Takiar, Vinita  (2023). Early treatment and toxicity outcomes for small posterior uveal melanomas treated using custom loaded eye plaques. Frontiers in medicine, 10, 1055141More Information

Korns, Julianna; McCauley, Shelby; Lehn, Maria; Takiar, Vinita; Sertorio, Mathieu; Lamba, Michael  (2023). Varied Photon Radiation Sources Produce Differences in Cellular Response. Radiation research, 199 (4) , 422-428More Information

Baniel, Claire C; Klebaner, Daniella; Beadle, Beth M; Ponce, Sara E Beltrán; Takiar, Vinita; Gibbs, Iris C; Soltys, Scott G; Bagshaw, Hilary P; Chang, Daniel T; Le, Quynh-Thu; Pollom, Erqi L  (2023). Reflections on the 2021 Accreditation Council for Graduate Medical Education and American Board of Radiology Family and Medical Leave of Absence Policies: An Opportunity to Increase Structural Support for Physicians. International journal of radiation oncology, biology, physics, 115 (1) , 19-22More Information

Galiveti, Chenna R; Kuhnell, Damaris; Biesiada, Jacek; Zhang, Xiang; Kelsey, Karl T; Takiar, Vinita; Tang, Alice L; Wise-Draper, Trisha M; Medvedovic, Mario; Kasper, Susan; Langevin, Scott M  (2023). Small extravesicular microRNA in head and neck squamous cell carcinoma and its potential as a liquid biopsy for early detection. Head & neck, 45 (1) , 212-224More Information

Crist, McKenzie; Yaniv, Benyamin; Palackdharry, Sarah; Lehn, Maria A; Medvedovic, Mario; Stone, Timothy; Gulati, Shuchi; Karivedu, Vidhya; Borchers, Michael; Fuhrman, Bethany; Crago, Audrey; Curry, Joseph; Martinez-Outschoorn, Ubaldo; Takiar, Vinita; Wise-Draper, Trisha M  (2022). Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition. Journal for immunotherapy of cancer, 10 (11) More Information

Wicker, Christina A; Petery, Taylor; Dubey, Poornima; Wise-Draper, Trisha M; Takiar, Vinita  (2022). Improving Radiotherapy Response in the Treatment of Head and Neck Cancer. Critical reviews in oncogenesis, 27 (2) , 73-84More Information

Mohamed, Abdallah S R; Martin, Geoffrey V; Ng, Sweet Ping; Takiar, Vinita; Beadle, Beth M; Zafereo, Mark; Garden, Adam S; Frank, Steven J; David Fuller, C; Brandon Gunn, G; Morrison, William H; Rosenthal, David I; Reddy, Jay; Moreno, Amy; Lee, Anna; Phan, Jack  (2024). Patterns of failure for recurrent head and neck squamous cell carcinoma treated with salvage surgery and postoperative IMRT reirradiation. Clinical and translational radiation oncology, 44, 100700More Information

Hanna, Glenn J; Chang, Steven Shih-Wei; Siddiqui, Farzan; Bain, Paul A; Takiar, Vinita; Ward, Matthew C; Shukla, Monica E; Hu, Kenneth S; Robbins, Jared; Witek, Matthew E; Bakst, Richard; Chandra, Ravi A; Galloway, Thomas; Margalit, Danielle N  (2023). Imaging and Biomarker Surveillance for Head and Neck Squamous cell carcinoma: A Systematic Review and Appropriate Use Criteria Document. International journal of radiation oncology, biology, physicsMore Information

Takiar, Vinita; Beadle, Beth M  (2023). In Regard to Razavian et al. International journal of radiation oncology, biology, physics, 117 (5) , 1298-1299More Information

Bouranis, John A; Wong, Carmen P; Beaver, Laura M; Uesugi, Sandra L; Papenhausen, Ethan M; Choi, Jaewoo; Davis, Edward W; Da Silva, Adilson Nunes; Kalengamaliro, Newton; Chaudhary, Rekha; Kharofa, Jordan; Takiar, Vinita; Herzog, Thomas J; Barrett, William; Ho, Emily  (2023). Sulforaphane Bioavailability in Healthy Subjects Fed a Single Serving of Fresh Broccoli Microgreens. Foods (Basel, Switzerland), 12 (20) More Information

Witek, Matthew E; Ward, Matthew C; Bakst, Richard; Chandra, Ravi A; Chang, Steven Shih-Wei; Choi, Karen Y; Galloway, Thomas; Hanna, Glenn J; Hu, Kenneth S; Robbins, Jared; Shukla, Monica E; Siddiqui, Farzan; Takiar, Vinita; Walker, Gary V; Fu, Yunting; Margalit, Danielle N  (2025). Paranasal Sinus and Nasal Cavity Cancers: Systematic Review and Executive Summary of the American Radium Society Appropriate Use Criteria. Head & neckMore Information

Sheth, Maulee; Sharma, Manju; Kongsomros, Supasek; Lehn, Maria; Takebe, Takanori; Takiar, Vinita; Wise-Draper, Trisha; Chutipongtanate, Somchai; Esfandiari, Leyla  (2025). Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo. bioRxiv : the preprint server for biologyMore Information

Mell, Loren K; Torres-Saavedra, Pedro A; Wong, Stuart J; Kish, Julie A; Chang, Steven S; Jordan, Richard C; Liu, Tian; Truong, Minh Tam; Winquist, Eric W; Takiar, Vinita; Wise-Draper, Trisha; Robbins, Jared R; Rodriguez, Cristina P; Awan, Musaddiq J; Beadle, Beth M; Henson, Christina; Narayan, Samir; Spencer, Sharon A; Powell, Steven; Dunlap, Neal; Sacco, Assuntina G; Hu, Kenneth Shung; Park, Henry S; Bauman, Julie E; Harris, Jonathan; Yom, Sue S; Le, Quynh-Thu  (2024). Radiotherapy with cetuximab or durvalumab for locoregionally advanced head and neck cancer in patients with a contraindication to cisplatin (NRG-HN004): an open-label, multicentre, parallel-group, randomised, phase 2/3 trial. The Lancet. Oncology, 25 (12) , 1576-1588More Information

Korns, Julianna; Wicker, Christina A; Lehn, Maria; Shyamsunder, Shreya; Thompson, Samuel; Lester, Carissa; Wise-Draper, Trisha M; Waltz, Susan E; Takiar, Vinita  (2024). Telaglenastat as an alternative to cisplatin as a radiosensitizer in the treatment of head and neck squamous cell carcinoma. Cancer letters, 606, 217320More Information

Sheth, Maulee; Sharma, Manju; Lehn, Maria; Reza, HasanAl; Takebe, Takanori; Takiar, Vinita; Wise-Draper, Trisha; Esfandiari, Leyla  (2024). Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. APL bioengineering, 8 (3) , 036106More Information

Zhou, Anna; Sharma, Anish; Kuhnell, Damaris; Hinrichs, Benjamin H; Kendler, Ady; Wang, Jiang; Dillehey-McKillip, Kelsey; Tang, Alice L; Takiar, Vinita; Wise-Draper, Trisha M; Langevin, Scott M  (2024). Multimodal assessment of high-risk human papillomavirus in sinonasal squamous cell carcinoma. Pathology, research and practice, 261, 155486More Information

Keltner, Samuel; Esslinger, Hope; Wu, Xiaoyong; Rai, Shesh; Takiar, Vinita  (2024). Refining Surveillance Guidelines after Stereotactic Body Radiation Therapy for Early-Stage Lung Cancer. Clinical lung cancer, 25 (6) , e268-e276.e1More Information

Petery, Taylor; Frankart, Andrew J; Esslinger, Hope; Wu, Xiaoyong; Rai, Shesh N; Takiar, Vinita  (2024). The effect of treatment package time on locally advanced oral cavity cancer outcomes. Oral oncology, 154, 106870More Information

Hosseinian, Seyedmohammadhossein; Kumar, Nitin; Takiar, Vinita; J Frankart, Andrew  (2025). Geometric optimization of dose distribution in spatially fractionated radiation therapy. Physics in medicine and biology, 70 (16) More Information

Rasmi, Rajan Radha; Kovatich, Rachel; Farley, Alyssa; Sakthivel, Kunnathur Murugesan; Takiar, Vinita; Sertorio, Mathieu  (2025). Targeting SREBP2 in cancer progression: Molecular mechanisms, oncogenic crosstalk, and therapeutic interventions. Cellular signalling, 135, 112044More Information

Shyamsunder, Shreya; Lu, Zhixin; Takiar, Vinita; Waltz, Susan E  (2025). Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms. Oncotarget, 16, 508-530More Information

Contact Information

Academic - UC Barrett Cancer Center
3151 Bellevue Avenue, ML 0757
Cincinnati  Ohio, 45219
Phone: 513-584-5668
Fax: 513-584-4007
takiarva@ucmail.uc.edu