Glenn Talaska

Glenn G Talaska

Professor, and Interim Chair, Department of Environmental Health

Kettering Lab Complex

130

COM Environmental Health - 0056

160 Panzeca Way
Cincinnati, Ohio 45267

Professional Summary

~~Glenn Talaska  is professor of Environmental Health at the University of Cincinnati College of Medicine.  He has a MSPH (Industrial Hygiene) from the University of Washington.  He earned his Ph.D. at the University of Texas Medical Branch.  Talaska was Research Toxicologist at the National Center for Toxicological Research.  Talaska’s research is on the development and validation of biomarkers of carcinogen exposure and effect.   Through the years this program has identified the major and disease- inducing carcinogen DNA adducts for bladder carcinogens 4-aminobiphenyl (tobacco smoke)  and benzidine (dye workers).    In addition he showed that the mechanism of action of benzidine DNA adducts was through the chromosomal aberrations they produced, while 4-aminobiphenyl caused specific mutations in cellular oncogenes.  The lab developed a method of carcinogen DNA adduct analysis that utilizes urothelial cells exfoliated into the urine as a source of target tissue DNA for bladder carcinogens; this allows easy non-invasive sampling of an internal target tissue.  This technique has allowed Talaska to study groups with occupational and environmental exposure to carcinogens.  For example, he has shown that adduct levels in exfoliated urothelial cells of non-smoking wives of smokers are 1.8 times higher than in the wives of non-smokers; and that the adduct levels in benzidine workers are 25 times higher than controls.  Glenn has published over 120 papers in journals such as Nature, PNAS, Cancer Research, JNCI,  Carcinogenesis as well as in the more specialized Industrial Hygiene journals.  He is on the editorial board of 5 Occupational and Public Health journals and has served as President of the Journal of Occupational and Environmental Health.  Talaska has successfully mentored 7 Ph. D. and 27 MS students to their degrees and is currently the mentor to 2 more MS students.   Talaska is the Vice-Chair of the ACGIH Biological Exposure Indices (BEI)  committee.  He is also Secretary of the Scientific Committee on Toxicology (SCOT) for the International Congress on Occupational Health.  Talaska has recently been appointed to the World Trade Center Health Program’s Scientific/Technical Advisory Committee.  He has been on the Scientific Advisory or Organizing Committees for over 15 international scientific meetings including every (triannual) International Society for Biological Monitoring  meeting since 1993.  Since 2001 Talaska has been the Chair of the University’s Radiation Safety Committee.   Talaska is the Associate Director of the Department of Environmental Health, the Director of the Environmental and Occupational Hygiene Division and Director of the Biomonitoring Component Program.  His current research is to determine the relationship between biomarkers of internal dose and reversible health effects in persons working with polycyclic aromatic hydrocarbons.  Groups studied include Firefighters, Coke Oven Workers and Tunnelers with the purpose to establish biological based exposure guidelines that will prevent disease in the millions of persons exposed to polycyclic aromatic compounds. 

Research Support

Grant: #263-NQ-605827 Investigators:Talaska, Glenn 03-08-2006 -03-07-2007 National Cancer Institute PAH-DNA Adducts in Lymphocytes and Bladder Cancer Risks Role:PI $22,500.00 Closed Level:Federal

Grant: #1004158,1003422 Investigators:Talaska, Glenn 12-01-2004 -01-24-2008 Department of the Army Medical Research Acquisition Activity Developing Biomonitoring Techniques Involving Microchip Applications Role:PI $235,872.00 Closed Level:Federal

Investigators:Talaska, Glenn 08-01-2004 -09-30-2005 National Cancer Institute Bulky DNA-Adducts in Lymphocyte DNA of Rubber Workers Role:PI $18,450.00 Closed Level:Federal

Investigators:Talaska, Glenn 07-01-2004 -12-31-2004 San Diego State University Foundation Influence of Maternal Nutrition and Environmental Exposure on Fetal Health Role:PI $10,400.00 Closed Level:Institution of Higher Education

Grant: #R01OH04124-03-A0-S0-E0 Investigators:Talaska, Glenn 09-30-1999 -09-29-2003 National Institute for Occupational Safety and Health Dermal Absorption Enhancers Affect Organotropism Role:PI $690,180.00 Closed Level:Federal

Grant: #1-263-MQ-007469-01-A0-S0-E0 Investigators:Talaska, Glenn 02-29-2000 -01-23-2001 National Cancer Institute DNA Adducts in the Bladder Cells of Rubber Workers Role:PI $24,997.00 Closed Level:Federal

Investigators:Talaska, Glenn 10-01-2000 -03-31-2005 World Cancer Research Fund Randomized Trial of Dietary Phenolics Role:PI $42,459.87 Closed Level:Foreign Non-Profit

Investigators:Talaska, Glenn 12-03-2001 -09-30-2004 Centers for Disease Control and Prevention Analysis of Biological Specimens for Specific Biomarkers for Exposure to Toxic and Carcinogenic Substances Role:PI $12,800.00 Closed Level:Federal

Grant: #SRS 004815 Investigators:Talaska, Glenn 03-01-2006 -12-31-2008 National Institute for Occupational Safety and Health Development of Skin Notations for 48 Chemicals Role:PI $15,000.00 Closed Level:Federal

Grant: #SRS 004896 Investigators:Talaska, Glenn 11-01-2005 -01-20-2006 Centre for Research in Environmental Epidemiology PAH-DNA Adducts in Lymphocytes and Bladder Cancer Risk Role:PI $20,000.00 Closed Level:Foreign Other

Grant: #5 U45 ES06162-17 Investigators:Genter, Mary Beth; Rice, Carol; Ross, Carol; Talaska, Glenn 08-01-2008 -07-31-2009 National Institute of Environmental Health Sciences ICWUC Worker Health and Safety Training Cooperative Role:Collaborator $55,215.00 Closed Level:Federal

Grant: #U45 ES061162 Investigators:Genter, Mary Beth; Rice, Carol; Ross, Clara; Talaska, Glenn 08-01-2009 -07-31-2010 National Institute of Environmental Health Sciences Worker Health and Safety Training Cooperative Agreement HWWT Role:Collaborator $53,741.00 Closed Level:Federal

Grant: #R01 OH009652 Investigators:Heineman, William; Seliskar, Carl; Talaska, Glenn 09-01-2009 -08-31-2012 National Institute for Occupational Safety and Health Target Organ DNA Damage in Coke Oven Workers Role:PI $451,635.00 Closed Level:Federal

Grant: #U45 ES06162 Investigators:Rice, Carol; Talaska, Glenn 08-01-2010 -07-31-2012 National Institute of Environmental Health Sciences Hazardous Material Worker Health and Safety Training Role:Collaborator $7,448.00 Closed Level:Federal

Grant: #U45 ES06162-19 Investigators:Genter, Mary Beth; Rice, Carol; Ross, Clara; Talaska, Glenn 08-01-2010 -07-31-2012 National Institute of Environmental Health Sciences Hazardous Material Worker Health and Safety Training Role:Collaborator $107,482.00 Closed Level:Federal

Grant: #T42 OH008432 Investigators:Banerjee, Rupak; Bhattacharya, Amit; Burroughs, Guy; Cardarelli, John; Davis, Kermit; Davis, Linda Sue; Genter, Mary Beth; Gillespie, Gordon; Grinshpun, Sergey; Haynes, Erin; Huston, Thomas; Jarrell, Judy; Jones, James; Kennerly, Susan; Kim, J.; Kupferle, Margaret; Lemasters, Grace; Lim, Teik; Lockey, James; McKay, Roy; Meyer, Mary-Ursula; Reid, Jon; Reponen, Tiina; Rice, Carol; Ross, Clara; Schulz, Mark; Shanov, Vesselin; Son, Sang Young; Spitz, Henry; Stuebbe, Philip; Talaska, Glenn; Yap, Tracey 07-01-2011 -06-30-2016 National Institute for Occupational Safety and Health Education and Research Center Role:Collaborator $6,006,722.00 Active Level:Federal

Grant: #HWWT / U45 ES06162-20 Investigators:Genter, Mary Beth; Rice, Carol; Ross, Clara; Talaska, Glenn 08-01-2011 -07-31-2012 National Institute of Environmental Health Sciences Worker Health and Safety Training Cooperative Agreement HWWT Role:Collaborator $53,741.00 Closed Level:Federal

Grant: #U45 ES06162 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2012 -07-31-2013 National Institute of Environmental Health Sciences Worker Health and Safety Training Cooperative Agreement ICWUC(HWWT) Role:Collaborator $53,741.00 Closed Level:Federal

Grant: #HWWT \ U45ES0612-22 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2013 -07-31-2014 National Institute of Environmental Health Sciences Worker Health and Safety Training Cooperative Agreement-HWWT Role:Collaborator $48,914.00 Closed Level:Federal

Grant: #Sub to 5U45ES0978-23 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 09-01-2014 -08-31-2015 National Institute of Environmental Health Sciences Worker Health and Safety Training for DOE Nuclear Weapons Workers Role:Collaborator $4,000.00 Active Level:Federal

Grant: #SUB 5U45ES06162-23 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2014 -07-31-2015 National Institute of Environmental Health Sciences Hazardous Materials Worker Health and Safety Training Cooperative (U45) HWWT ES06162 Role:Collaborator $53,741.00 Active Level:Federal

Grant: #T42OH008432 Investigators:Bhattacharya, Amit; Davis, Kermit; Freeman, Andrew; Kim, J.; Reponen, Tiina; Reutman, Susan; Talaska, Glenn 07-01-2016 -06-30-2021 National Institute for Occupational Safety and Health Education and Research Center (ERC - Cincinnati) Role:Collaborator $1,702,965.00 Active Level:Federal

Grant: #ICWUC HWWT/ 5U45ES06162-25 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2016 -07-31-2017 National Institute of Environmental Health Sciences Hazardous Materials Worker Health and Safety Training (U45) (HWWT) Role:Collaborator $50,053.00 Awarded Level:Federal

Grant: #ICWUC HWWT_U45ES06162-26 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2017 -07-31-2018 National Institute of Environmental Health Sciences Hazardous Materials Worker Health and Safety Training (U45) (HWWT) Role:Collaborator $50,053.00 Active Level:Federal

Grant: #HWWT / U45ES06162 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2018 -07-31-2019 National Institute of Environmental Health Sciences Hazardous Materials Worker Health and Safety Training (U45) (HWWT) Role:Collaborator $43,040.00 Awarded Level:Federal

Grant: #HWWT / U45ES06162 Investigators:Freeman, Andrew; Genter, Mary Beth; Rice, Carol; Talaska, Glenn 08-01-2019 -07-31-2020 National Institute of Environmental Health Sciences Hazardous Materials Worker Health and Safety Training (U45) (HWWT) Role:Collaborator $43,040.00 Awarded Level:Federal

Grant: #OSHA SHO5166SH9 Investigators:Talaska, Glenn 09-30-2019 -09-30-2020 Occupational Safety & Health Administration Training Capacity Building in Trenching and Excavation Role:PI $180,000.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Ward, E M; Sabbioni, G; DeBord, D G; Teass, A W; Brown, K K; Talaska, G G; Roberts, D R; Ruder, A M; Streicher, R P (1996. )Monitoring of aromatic amine exposures in workers at a chemical plant with a known bladder cancer excess. Journal of the National Cancer Institute, ,88 (15 ),1046-52

Research and Practice Interests

Contact Information

Academic - 160 Panzeca Way
Cincinnati  Ohio, 45267
Phone: 513-558-5701
Glenn.Talaska@uc.edu