Education
PhD: University of Connecticut 1973 (Developmental Biology)
Research and Practice Interests
My main research interest concerns metal-based drugs and the use of cell culture models in determination of mechanism of action. We have been studying gold-based drugs used to treat rheumatoid arthritis for a number of years and have identified specific gold containing metabolites in patient fluids. We are now studying the interaction of these metabolites with cultured cells and have recently begun studies aimed at determining whether any of these metabolites can inhibit replication of the AIDS virus.
Positions and Work Experience
09-01-1974 -08-31-1975 Visiting Instructor, Taught introductory biology and genetics courses, Middlebury College, Middlebury, Vermont
09-01-1975 -06-01-1976 Visiting Assistant Professor, Taught courses in cell biology and developmental biology, Middlebury College, Middlebury, Vermont
09-01-1976 -08-31-1983 Assistant Professor, University of Cincinnati, Cincinnati, OH
09-01-1983 -08-31-1998 Associate Professor, University of Cincinnati, Cincinnati, OH
09-01-1998 - Professor, University of Cincinnati, Cincinnati, OH
Abbreviated Publications
Peer Reviewed Publications
Vonderheide, A.P., Meija, J., Tepperman, K., Puga, A., Pinhas, A.R., States, C.J., & Caruso, J (2004). Retention of Cr(III) by high performance chelation ion chromatography interfaced to inductively coupled plasma mass spectrometric detection with collision cell. J. Chromatog. A, 1024, 129-137.
Wei, Y.-D., Tepperman, K., Huang, M., Sartor, M.A., & Puga, A. (2004). Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. J. Biochem., 279, 4110-4119.
Service
(Teaching Effeciveness Committee ) Committee Chair Type:Departmental Service Level:Department 09-01-2004
(Undergraduate Affairs Committee ) Committee Chair Type:Departmental Service Level:Department 09-01-2003
(Workload ) Co-Chair Type:Departmental Service Level:University 09-01-2004
(Undergraduate Council ) Committee Member Type:University/College Service Level:College 09-01-2004
Post Graduate Training and Education
07-01-1974-06-30-1976 Postdoctoral Fellow, Research on turnover of membrane proteins in cultured skeletal muscle cells, Carnegie Institution of Washington Department of Embryology, , Baltimore, MD
Courses Taught
15-BIOL-301 CELL STRUCT FUNCTN Level:Undergraduate
15-BIOL-321 RESEARCH & CAREERS Level:Undergraduate
15-BIOL-321 RESEARCH & CAREERS Level:Undergraduate
15-BIOL-573 DEVEL BIOLOGY Level:Both
15-BIOL-642 ADV CELL BIOLOGY Level:Both
15-BIOL-321 RESEARCH & CAREERS Level:Undergraduate