Katherine Elizabeth Vest, PhD

Bachelor of Science: Auburn University Auburn, AL, 2008 (Microbiology)

Doctoral Degree: Auburn University Auburn, AL, 2013 (Biology)

Postdoctoral Fellowship: Emory University School of Medicine Atlanta, GA, 2017 ( )

Postdoctoral Fellowship: Emory University Atlanta, GA, 2018

Molecular Biology, RNA Biology, Skeletal Muscle Regeneration, Trace Element Homeostasis

Grant: #R25098 Investigators:Vest, Katherine 03-01-2021 -03-31-2023 UC's URC Faculty Scholars Program URC-Faculty Scholars Res Awd-Vest Role:PI $25,000.00 Active Level:Internal UC

Grant: #R35GM146878 (MIRA) Investigators:Vest, Katherine 08-01-2022 -05-31-2027 National Institute of General Medical Sciences Function and regulation of copper in mammalian tissue differentiation Role:PI 405000.00 Awarded Level:Federal

Grant: #R01CA287260 Investigators:Cunningham, John; Czyzyk-Krzeska, Maria; Meller, Jaroslaw; Vest, Katherine 09-20-2023 -08-31-2028 National Cancer Institute Metabolic effects of cooper in renal cancer Role:Collaborator 693769.38 Hold Level:Federal

Grant: #1R01AG084718 - 01 Investigators:Grillo, Anthony; Vest, Katherine 04-01-2024 -08-31-2028 National Institute on Aging Probing the tissue-specific mechanisms and therapeutic potential of mTOR inhibition in branched chain amino acid-related diseases. Role:Collaborator 0.00 Hold Level:Federal

Grant: #R01AG084718-01 Investigators:Grillo, Anthony; Vest, Katherine 04-01-2024 -08-31-2028 National Institute on Aging Probing the tissue-specific mechanisms and therapeutic potential of mTOR inhibition in branched chain amino acid-related diseases. Role:Collaborator 233761.00 Hold Level:Federal

Peer Reviewed Publications

Vest, Katherine E; Paskavitz, Amanda L; Lee, Joseph B; Padilla-Benavides, Teresita  (2018). Dynamic changes in copper homeostasis and post-transcriptional regulation of Atp7a during myogenic differentiation. Metallomics : integrated biometal science, 10 (2) , 309-322More Information

Boulet, Aren; Vest, Katherine E; Maynard, Margaret K; Gammon, Micah G; Russell, Antoinette C; Mathews, Alexander T; Cole, Shelbie E; Zhu, Xinyu; Phillips, Casey B; Kwong, Jennifer Q; Dodani, Sheel C; Leary, Scot C; Cobine, Paul A  (2018). The mammalian phosphate carrier SLC25A3 is a mitochondrial copper transporter required for cytochrome c oxidase biogenesis. The Journal of biological chemistry, 293 (6) , 1887-1896More Information

Banerjee, Ayan; Vest, Katherine E; Pavlath, Grace K; Corbett, Anita H  (2017). Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing. Nucleic acids research, 45 (18) , 10706-10725More Information

Choo, Hyo-Jung; Canner, James P; Vest, Katherine E; Thompson, Zachary; Pavlath, Grace K  (2017). A tale of two niches: differential functions for VCAM-1 in satellite cells under basal and injured conditions. American journal of physiology. Cell physiology, 313 (4) , C392-C404More Information

Vest, Katherine E; Phillips, Brittany L; Banerjee, Ayan; Apponi, Luciano H; Dammer, Eric B; Xu, Weiting; Zheng, Dinghai; Yu, Julia; Tian, Bin; Pavlath, Grace K; Corbett, Anita H  (2017). Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology. Human molecular genetics, 26 (17) , 3235-3252More Information

Vest, Katherine E; Wang, Jing; Gammon, Micah G; Maynard, Margaret K; White, Olivia L; Cobine, Jai A; Mahone, Wilkerson K; Cobine, Paul A  (2016). Overlap of copper and iron uptake systems in mitochondria in Saccharomyces cerevisiae. Open biology, 6 (1) , 150223More Information

Randolph, Matthew E; Phillips, Brittany L; Choo, Hyo-Jung; Vest, Katherine E; Vera, Yandery; Pavlath, Grace K  (2015). Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance. Stem cells (Dayton, Ohio), 33 (12) , 3581-95More Information

Vest, Katherine E; Apponi, Luciano H; Banerjee, Ayan; Pavlath, Grace K; Corbett, Anita H  (2015). An Antibody to Detect Alanine-Expanded PABPN1: A New Tool to Study Oculopharyngeal Muscular Dystrophy. Journal of neuromuscular diseases, 2 (4) , 439-446More Information

Randolph, Matthew E; Luo, Qingwei; Ho, Justin; Vest, Katherine E; Sokoloff, Alan J; Pavlath, Grace K  (2014). Ageing and muscular dystrophy differentially affect murine pharyngeal muscles in a region-dependent manner. The Journal of physiology, 592 (23) , 5301-15More Information

Vest, Katherine E; Leary, Scot C; Winge, Dennis R; Cobine, Paul A  (2013). Copper import into the mitochondrial matrix in Saccharomyces cerevisiae is mediated by Pic2, a mitochondrial carrier family protein. The Journal of biological chemistry, 288 (33) , 23884-92More Information

Vest, Katherine E; Hashemi, Hayaa F; Cobine, Paul A  (2013). The copper metallome in eukaryotic cells. Metal ions in life sciences, 12, 451-78More Information

Bischoff, Megan E; Shamsaei, Behrouz; Yang, Juechen; Secic, Dina; Vemuri, Bhargav; Reisz, Julie A; D'Alessandro, Angelo; Bartolacci, Caterina; Adamczak, Rafal; Schmidt, Lucas; Wang, Jiang; Martines, Amelia; Biesiada, Jacek; Vest, Katherine E; Scaglioni, Pier P; Plas, David R; Patra, Krushna C; Gulati, Shuchi; Figueroa, Julio A Landero; Meller, Jarek; Cunningham, J Tom; Czyzyk-Krzeska, Maria F  (2024). Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma. bioRxiv : the preprint server for biologyMore Information

Whitlow, Thomas J; Zhang, Yu; Ferguson, Nathan; Perez, Alexandra M; Patel, Hemchandra; Link-Kemp, Josephine A; Larson, Ethan M; Mezzell, Allison T; Shanbhag, Vinit C; Petris, Michael J; Vest, Katherine E  (2023). Regulation of Atp7a RNA contributes to differentiation-dependent Cu redistribution in skeletal muscle cells. Metallomics : integrated biometal science, 15 (7) More Information

Padilla-Benavides, Teresita; Vest, Katherine E; Campos-Parra, Alma D; Raimunda, Daniel  (2023). Editorial: Novel approaches to study metals in molecular biology. Frontiers in molecular biosciences, 10, 1167896More Information

Zhang, Yu; Zeuthen, Christopher; Zhu, Carol; Wu, Fang; Mezzell, Allison T; Whitlow, Thomas J; Choo, Hyojung J; Vest, Katherine E  (2022). Pharyngeal pathology in a mouse model of oculopharyngeal muscular dystrophy is associated with impaired basal autophagy in myoblasts. Frontiers in cell and developmental biology, 10, 986930More Information

Kim, Eunhye; Wu, Fang; Lim, Danbi; Zeuthen, Christopher; Zhang, Yiming; Allen, James; Muraine, Laura; Trollet, Capucine; Vest, Katherine E; Choo, Hyojung J  (2022). Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion. Frontiers in cell and developmental biology, 10, 875209More Information

Janice Sánchez, Brenda; Tremblay, Anne-Marie K; Leduc-Gaudet, Jean-Philippe; Hall, Derek T; Kovacs, Erzsebet; Ma, Jennifer F; Mubaid, Souad; Hallauer, Patricia L; Phillips, Brittany L; Vest, Katherine E; Corbett, Anita H; Kontoyiannis, Dimitris L; Hussain, Sabah N A; Hastings, Kenneth E M; Di Marco, Sergio; Gallouzi, Imed-Eddine  (2019). Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy. Nature communications, 10 (1) , 4171More Information

Gordon, Shellaina J V; Fenker, Daniel E; Vest, Katherine E; Padilla-Benavides, Teresita  (2019). Manganese influx and expression of ZIP8 is essential in primary myoblasts and contributes to activation of SOD2. Metallomics : integrated biometal science, 11 (6) , 1140-1153More Information

Banerjee, Ayan; Phillips, Brittany L; Deng, Quidong; Seyfried, Nicholas T; Pavlath, Grace K; Vest, Katherine E; Corbett, Anita H  (2019). Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle. The Journal of biological chemistry, 294 (18) , 7360-7376More Information

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