Jiang Wang

Jiang Wang

Professor; Director of Surgical Pathology

Education

Medical Degree, Henan Medical University, Zhengzhou Henan, China, 1985

Doctorate, Henan Medical University, Zhengzhou Henan, China, 1997

Residency, University of Cincinnati College of Medicine Cincinnati, OH, 2007 (Pathology-Anatomic and Clinical )

Fellowship, Yale University School of Medicine 2008 (Surgical Pathology )

Positions and Work Experience

- Assistant Professor, Department of Pathology and Laboratory Medicine, Lab Medicine Building 124

Research and Practice Interests

Surgical pathology, GI/ Liver pathology, Transplant pathology, Cytopathology

UC Health Clinical Focus

Pathology

UC Health Specialities

Pathology

Certifications

American Board of Pathology (Anatomic Pathology)

07/31/2008

Research Support

Grant: #W81XWH-08-1-0370 Investigators:Kasper, Susan; Wang, Jiang 07-01-2008 -04-14-2013 Department of the Army Medical Research Acquisition Activity DJ-1 in the Development of Hormone Refractory Prostate Cancer Role:Collaborator $568,378.00 Active Level:Federal

Grant: #SRS 007871 Investigators:Wang, Jiang; Wang, Shao-Chun 01-01-2012 -02-28-2014 Elsa U. Pardee Foundation An Efficient Targeted Strategy Against Endocrine- Resistant and Triple-Negative Breast Cancer Role:Collaborator $125,000.00 Active Level:Private Non-Profit

Grant: #R01CA158323 Investigators:Du, Chunying; Porollo, Alexey; Wang, Jiang 05-01-2012 -03-31-2017 National Cancer Institute Studies of Lymphoma Suppression and DNA Repair Role:Collaborator $632,004.00 Active Level:Federal

Grant: #W81XWH-08-1-0370 Investigators:Kasper, Susan; Wang, Jiang 07-01-2008 -04-14-2013 Department of the Army Medical Research Acquisition Activity DJ-1 in the Development of Hormone Refractory Prostate Cancer Role:Collaborator $568,378.00 Closed Level:Federal

Grant: #OSOTC14CQ Investigators:Shah, Shimul; Wang, Jiang 01-01-2014 -12-31-2014 Ohio Solid Organ Transplantation Consortium Decreasing steatosis of fatty donor lives utlizing normothermic machine perfusion preservation and a pharmacologic def Role:Collaborator $3,500.00 Active Level:Private Non-Profit

Grant: #135658 / W81XWH-15-1-0370 Investigators:Lentsch, Alex; Wang, Jiang 09-30-2015 -09-29-2018 Department of the Army Medical Research Acquisition Activity Mechanisms of nonalcoholic steatohepatitis Role:PI $3,600.00 Awarded Level:Federal

Grant: #R01CA158439 Investigators:Ahmad, Syed; Chadalavada, Seetharam; Choe, K. Ann; Mast, T. Douglas; Rao, Marepalli; Ristagno, Ross; Shah, Shimul; Wang, Jiang 06-01-2018 -05-31-2023 National Cancer Institute Monitoring and control of human liver cancer ablation using real-time, 3D echo decorrelation imaging Role:Collaborator $437,316.00 Awarded Level:Federal

Grant: #1R21CA241025-01 Investigators:Du, Chunying; Niu, Liang; Wang, Jiang 09-02-2019 -08-31-2021 National Institutes of Health Novel Targeting of Liver Cancer Deficient of DNA Repair Role:Collaborator $209,453.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Tevar, Amit D; Clarke, Callisia N; Schuster, Rebecca; Wang, Jiang; Edwards, Michael J; Lentsch, Alex B (2011. )The Effect of Hepatic Ischemia Reperfusion Injury in a Murine Model of Nonalcoholic Steatohepatitis .J Surg Res, ,(169 ),e7-14

Dong, Zhongyun; Liu, Yin; Scott, Kieran F; Levin, Linda; Gaitonde, Krishnanath; Bracken, R Bruce; Burke, Barbara; Zhai, Qihui Jim; Wang, Jiang; Oleksowicz, Leslie; Lu, Shan (2010. )Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer.Carcinogenesis, ,31 (11 ),1948-55

Tevar, Amit D; Clarke, Calissia; Wang, Jiang; Rudich, Steven M; Woodle, E Steve; Lentsch, Alex B; Edwards, Michael L (2010. )Clinical review of nonalcoholic steatohepatitis in liver surgery and transplantation.Journal of the American College of Surgeons, ,210 (4 ),515-26

Kashif Ahmed, Jeffery Sussman, Jiang Wang, Nathan Schmulewitz (12-17-2010. )A case of EUS-FNA-related pancreatic cancer metastasis to the stomach .Gastrointestinal Endoscopy, ,Epub ahead of print ,

Dongrong Situ, Hao Long, Peng Lin, Zhihua Zhu, Jiang Wang, Xu Zhang, Zeming Xie, and Tiehua Rong (2010. )Expression and prognostic relevance of CD44v6 in stage I non-small cell lung carcinoma .J Cancer Res Clin Oncol, ,136 (8 ),1213-9

Jared T. Hagaman, Bryce Ferguson, Cris Meyer, Jiang Wang, Francis X. McCormack, Amaresh Nath (2010. )Endobronchial Carcinoid Tumor in an HIV-infected Patient .J Bronchology and Interventional Pulmonology, ,17 ,174-176

Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan (2011. )Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer .Oncology reports, ,25 (6 ),1511-6

Navaneethan, Udayakumar; Lancaster, Elisha; Venkatesh, Preethi Gk; Wang, Jiang; Neff1, Guy W (2011. )Herpes simplex virus hepatitis - it's high time we consider empiric treatment .Journal of gastrointestinal and liver diseases : JGLD, ,20 (1 ),93-96

Ahmed, Kashif; Sussman, Jeffrey J; Wang, Jiang; Schmulewitz, Nathan (2010. )A case of EUS-guided FNA-related pancreatic cancer metastasis to the stomach.Gastrointestinal endoscopy, ,

Dragovich, Tomislav; McCoy, Sheryl; Fenoglio-Preiser, Cecilia M; Wang, Jiang; Benedetti, Jacqueline K; Baker, Amanda F; Hackett, Christopher B; Urba, Susan G; Zaner, Ken S; Blanke, Charles D; Abbruzzese, James L (2006. )Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, ,24 (30 ),4922-7

Xu, Meifeng; Wani, Maqsood; Dai, Yan-Shan; Wang, Jiang; Yan, Mei; Ayub, Ahmar; Ashraf, Muhammad (2004. )Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes.Circulation, ,110 (17 ),2658-65

Gleich, Lyon L; Wang, Jiang; Gluckman, Jack L; Fenoglio-Preiser, Cecilia M Microsatellite instability as a predictor of survival in head and neck cancer -- is there a link with colon cancer?.ORL, ,65 (4 ),193-8

Clements, Wilson M; Wang, Jiang; Sarnaik, Amod; Kim, On Ja; MacDonald, Jack; Fenoglio-Preiser, Cecilia; Groden, Joanna; Lowy, Andrew M (2002. )beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer .Cancer research, ,62 (12 ),3503-6

K. Ahmed, K. Safdar, N. Kemmer, M. Atiq, J. Wang, G. Neff (2007. )Intestinal schistosomiasis following orthotopic liver transplantation: a case report .Transplantation Proceedings, ,39 ,3502-3504

Fenoglio-Preiser CM, Wang J, Stemmermann GN, Noffsinger A. (2003. )TP53 and gastric carcinoma: A review .Hum Mutat, ,21 (3 ),258-270

Shepherd T, Tolbert D, Benedetti J, Macdonald JS, Wiest J, DeVoe G, Jiang Wang, Noffsinger A, Stemmermann GN, Fenoglio-Preiser CM (2000. )Alterations in exon 4 of the p53 gene in gastric carcinoma .Gastroenterology, ,118 (6 ),1039-44

Jiang Wang, Amy Noffsinger, Grant Stemmermann, and Cecilia Fenoglio-Preiser (1999. )Esophageal squamous cell carcinomas arising in patients from a high-risk area of north China lack an association with Epstein-Barr virus .Cancer Epidemiology Biomarkers & Prevention, ,(8 ),1111-1114

Cui J, Germer K, Wu T, Wang J, Luo J, Wang SC, Wang Q, Zhang X (2012. )Crosstalk Between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells .Cancer Res, ,2012 Sep 10 ,[Epub ahead of print]

Zahedi K, Barone SL, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Casero RA Jr, Soleimani M (2012. )Hepatocyte specific ablation of spermine/spermidine-N1-acetyltransferase (SSAT) gene reduces the severity of CCl4-induced acute liver injury .Am J Physiol Gastrointest Liver Physiol, ,303 (5 ),G546-60

Pengyuan Liu, Carl Morrison, Liang Wang, Donghai Xiong, Peter Verdell, Peng Cui, Feng Ding, Yan Lu, Karen Head, Jaime W. Andrae, Michael R. Tschannen, Howard Jacob, Jing Pan, Qi Zhang, Francoise Van den Bergh, Haijie Xiao, Ken C. Lo, Jigar Patel, Todd Richmond, Mary-Anne Watt, Thomas Albert, Rebecca Selzer, Marshall Anderson, Jiang Wang, Yian Wang, Sandra Starnes, Ping Yang, Ming You (2012. )Identification of somatic mutations in non-small cell lung carcinoma using whole –exome sequencing .Carcinogenesis, ,33 (7 ),1270-6

Hung-Ming Lam, Suresh Babu, Jiang Wang, Yong Yuan, Ying-Wai Lam, Shuk-Mei Ho, Yuet-Kin Leung (2012. )Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion .Mol Cell Endocrinal, ,358 (1 ),27-35

Starnes SL, Pathrose P, Wang J, Succop P, Morris JC, Bridges J, Kupert EY, Anderson M (2012. )Clinical and Molecular Predictors of Recurrence in Stage I Non-Small Cell Lung Cancer .Ann Thorac Surg, ,93 (5 ),1606-12

Raza A, Yousaf W, Ahmed K, Muntel E, Wang J, Rood RP (2011. )Protein-Losing Enteropathy in a Post-partum Female Secondary to Metastatic Melanoma of the Gut: Report of a Case .J Gastrointest Cancer, ,October 18 ,[Epub ahead of print]

Elena Kupert, Marshall Anderson, Yin Liu, Paul Succop, Linda Levin, Jiang Wang, Kathryn Wikenheiser-brokamp, Pingping Chen, Susan Pinney, Trudy Macdonald, Zhongyun Dong, Sandra Starnes, and Shan Lu (2011. )Plasma Secretory Phospholipase A2-IIa as a Potential Biomarker for Lung Cancer .BMC Cancer, ,11 (1 ),513

Udayakumar Navaneethan, Elisha Lancaster, Jiang Wang, Guy W. Neff (2011. )Herpes simplex hepatitis-It’s high time we consider empiric treatment .J Gastrointestinal Liver Dis, ,20 (1 ),93-96

Kumar, Sudhir; Wang, Jiang; Rani, Richa; Gandhi, Chandrashekhar R (2016. )Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice.PloS one, ,11 (1 ),e0147864

Wang, Yuan-Liang; Overstreet, Anne-Marie; Chen, Min-Shan; Wang, Jiang; Zhao, Hua-Jun; Ho, Po-Chun; Smith, Molly; Wang, Shao-Chun (2015. )Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR.Oncotarget, ,6 (13 ),11150-61

Garrison, Jason B; Ge, Chunmin; Che, Lixiao; Pullum, Derek A; Peng, Guang; Khan, Sohaib; Ben-Jonathan, Nira; Wang, Jiang; Du, Chunying (2015. )Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents.Journal of cancer science & therapy, ,7 (4 ),121-126

Engevik, Melinda A; Yacyshyn, Mary Beth; Engevik, Kristen A; Wang, Jiang; Darien, Benjamin; Hassett, Daniel J; Yacyshyn, Bruce R; Worrell, Roger T (2015. )Human Clostridium difficile infection: altered mucus production and composition.American journal of physiology. Gastrointestinal and liver physiology, ,308 (6 ),G510-24

Engevik, Melinda A; Engevik, Kristen A; Yacyshyn, Mary Beth; Wang, Jiang; Hassett, Daniel J; Darien, Benjamin; Yacyshyn, Bruce R; Worrell, Roger T (2015. )Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile.American journal of physiology. Gastrointestinal and liver physiology, ,308 (6 ),G497-509

Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B (2015. )Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice.Hepatology research : the official journal of the Japan Society of Hepatology, ,45 (3 ),305-14

Gandhi, Chandrashekhar R; Chaillet, J Richard; Nalesnik, Michael A; Kumar, Sudhir; Dangi, Anil; Demetris, A Jake; Ferrell, Robert; Wu, Tong; Divanovic, Senad; Stankeiwicz, Traci; Shaffer, Benjamin; Stolz, Donna B; Harvey, Stephen A K; Wang, Jiang; Starzl, Thomas E (2015. )Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice.Gastroenterology, ,148 (2 ),379-391.e4

Fisher, Alexander V; Sutton, Jeffrey M; Wilson, Gregory C; Hanseman, Dennis J; Abbott, Daniel E; Smith, Milton T; Schmulewitz, Nathan; Choe, Kyran A; Wang, Jiang; Sussman, Jeffrey J; Ahmad, Syed A (2014. )High readmission rates after surgery for chronic pancreatitis.Surgery, ,156 (4 ),787-94

Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan (2014. )Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells.International journal of oncology, ,45 (3 ),978-84

Ahmad, Nisar; Adams, Denise M; Wang, Jiang; Prakash, Rajan; Karim, Nagla Abdel (2014. )Hepatic epithelioid hemangioendothelioma in a patient with hemochromatosis. Journal of the National Comprehensive Cancer Network : JNCCN, ,12 (9 ),1203-7

Lutz, Eric R; Wu, Annie A; Bigelow, Elaine; Sharma, Rajni; Mo, Guanglan; Soares, Kevin; Solt, Sara; Dorman, Alvin; Wamwea, Anthony; Yager, Allison; Laheru, Daniel; Wolfgang, Christopher L; Wang, Jiang; Hruban, Ralph H; Anders, Robert A; Jaffee, Elizabeth M; Zheng, Lei (2014. )Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation.Cancer immunology research, ,2 (7 ),616-31

Ghose, Abhimanyu; Morris, John C; Breneman, John C; Essell, James; Wang, Jiang; Benzaquen, Sadia Medulloblastoma in an Adult With Late Extraneural Metastases to the Mediastinum.Journal of investigative medicine high impact case reports, ,2 (2 ),2324709614532798

Namad, Tariq; Wang, Jiang; Tilton, Annemarie; Abdel Karim, Nagla (2014. )Bilateral choroidal metastasis from non-small cell lung cancer.Case reports in oncological medicine, ,2014 ,858265

Taftaf, Rokana; Starnes, Sandra; Wang, Jiang; Shipley, Ralph; Namad, Tariq; Khaled, Rana; Abdel Karim, Nagla (2014. )Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature.Case reports in oncological medicine, ,2014 ,842801

Lam, Hung-Ming; Ouyang, Bin; Chen, Jing; Ying, Jun; Wang, Jiang; Wu, Chin-Lee; Jia, Li; Medvedovic, Mario; Vessella, Robert L; Ho, Shuk-Mei (2014. )Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer.Endocrine-related cancer, ,21 (6 ),903-14

Bahassi, El Mustapha; Li, Ya-Qin; Wise-Draper, Trisha M; Deng, Li; Wang, Jiang; Darnell, Colleen N; Wilson, Keith M; Wells, Susanne I; Stambrook, Peter J; Rixe, Olivier (2013. )A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer.European journal of cancer (Oxford, England : 1990), ,49 (10 ),2345-55

Shen, Ling; Xiong, Ye; Wang, David Q-H; Howles, Philip; Basford, Joshua E; Wang, Jiang; Xiong, Yu Qing; Hui, David Y; Woods, Stephen C; Liu, Min (2013. )Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats.Journal of lipid research, ,54 (5 ),1430-8

Namad, Tariq; Wang, Jiang; Shipley, Ralph; Abdel Karim, Nagla (2013. )Thyroid metastasis from nonsmall cell lung cancer.Case reports in oncological medicine, ,2013 ,208213

Cui, Jiajun; Germer, Katherine; Wu, Tianying; Wang, Jiang; Luo, Jia; Wang, Shao-chun; Wang, Qianben; Zhang, Xiaoting (2012. )Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells.Cancer research, ,72 (21 ),5625-34

Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher (2012. )Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury.American journal of physiology. Gastrointestinal and liver physiology, ,303 (5 ),G546-60

Raza, Ali; Yousaf, Wajeeha; Ahmed, Kashif; Muntel, Emily; Wang, Jiang; Rood, Richard P (2012. )Protein-Losing Enteropathy in a Post-partum Female Secondary to Metastatic Melanoma of the Gut: Report of a Case.Journal of gastrointestinal cancer, ,43 Suppl 1 ,S148-50

Lam, Hung-Ming; Suresh Babu, C V; Wang, Jiang; Yuan, Yong; Lam, Ying-Wai; Ho, Shuk-Mei; Leung, Yuet-Kin (2012. )Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion.Molecular and cellular endocrinology, ,358 (1 ),27-35

Liu, Pengyuan; Morrison, Carl; Wang, Liang; Xiong, Donghai; Vedell, Peter; Cui, Peng; Hua, Xing; Ding, Feng; Lu, Yan; James, Michael; Ebben, John D; Xu, Haiming; Adjei, Alex A; Head, Karen; Andrae, Jaime W; Tschannen, Michael R; Jacob, Howard; Pan, Jing; Zhang, Qi; Van den Bergh, Francoise; Xiao, Haijie; Lo, Ken C; Patel, Jigar; Richmond, Todd; Watt, Mary-Anne; Albert, Thomas; Selzer, Rebecca; Anderson, Marshall; Wang, Jiang; Wang, Yian; Starnes, Sandra; Yang, Ping; You, Ming (2012. )Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.Carcinogenesis, ,33 (7 ),1270-6

Starnes, Sandra L; Pathrose, Peterson; Wang, Jiang; Succop, Paul; Morris, John C; Bridges, James; Kupert, Elena Y; Anderson, Marshall (2012. )Clinical and molecular predictors of recurrence in stage I non-small cell lung cancer.The Annals of thoracic surgery, ,93 (5 ),1606-12

Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan (2011. )Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules.BMC cancer, ,11 ,513

Hagaman, Jared T; Ferguson, Bryce; Meyer, Cris; Wang, Jiang; McCormack, Francis X; Nath, Amaresh (2010. )Endobronchial Carcinoid Tumor in an HIV-infected Patient.Journal of bronchology & interventional pulmonology, ,17 (2 ),174-6

Contact Information

Academic - UC Health University Hospital
234 Goodman Street
Cincinnati  Ohio, 45219-0533
Phone: (513) 584-7284
Fax: (513) 584-3892
Jiang.Wang@uc.edu