
Kyle Walsh , MD
Associate Professor of Clinical
Attending Physician Emergency Medicine, Neurocritical Care, UC Stroke Team
University of Cincinnati College of Medicine
Department of Emergency Medicine
231 Albert Sabin Way, MSB 1654
Cincinnati , Ohio 45267-0769
Phone 513-558-5281
Fax 513-558-5791
Email Kyle.Walsh@uc.edu
Education
Bachelor's Degree: Michigan State University (Biology)
Medical Degree: Michigan State University
Residency Training: University of Cincinnati 2015 (Emergency Medicine)
Certifications
American Board of Emergency Medicine (Certification Date: 05-16-2016 )
United Council for Neurologic Subspecialties (Certification Date: 12-01-2019 )
Clinical Interests
Emergency Medicine
Stroke
Acute Stroke
Cerebrovascular Disorders
Hemorrhagic Stroke
Intracranial Hemorrhages
Ischemic Stroke
Neurogenic Inflammation
Stroke, including Hemorrhagic Stroke and Ischemic Stroke
Stroke-Related Cognitive Dysfunction
Vascular Cognitive Impairment
Specialities
Emergency Medicine
Neurocritical Care
Research and Practice Interests
Research Support
Grant: #SBIR Phase II / NSF 1632270 Investigators:Hartings, Jed; Walsh, Kyle 06-01-2017 -05-31-2018 National Science Foundation SBIR Phase II: Novel Device for Monitoring Brain Hemorrhage Using Radio Waves Role:PI $127,396.00 Active Level:Federal
Grant: #SBIR PHIIB / IIP-1632270-001 Investigators:Walsh, Kyle 06-22-2020 -06-22-2021 National Science Foundation Technology Enhancement for Commercial Partnerships; NSF# 1632270 Role:PI $32,342.00 Awarded Level:Federal
Grant: #20TPA35490044 Investigators:Walsh, Kyle 01-01-2021 -12-31-2023 American Heart Association - National Chapter Serial RNA-seq in Acute ICH Patients: Association with 90-day Outcomes and Identification of Novel Treatment Targets Role:PI $100,000.00 Awarded Level:Private Non-Profit
Grant: #SENSE-006 Investigators:Walsh, Kyle 10-01-2021 -10-01-2024 Sense Diagnostics, LLC A Retrospective Evaluation of SENSE-003's Impact on Routine Care Role:PI 0.00 Hold Level:Industry
Investigators:Walsh, Kyle 02-18-2022 -02-17-2025 Sense Diagnostics, LLC A Prospective, Non-randomized, Sequentially-enrolled, Multi-center, Phase II Study to Evaluate the SENSE Device's Ability to Detect and Monitor Traumatic Brain Injury Role:PI 64705.50 Hold Level:Industry
Grant: #R01NS128425 Investigators:Esfandiari, Leyla; Langevin, Scott; Walsh, Kyle; Woo, Daniel 07-19-2022 -06-30-2027 National Institute of Neurological Disorders and Stroke CAPSTONE: Central And Peripheral STrOke inflammatioN with Exosomes Role:PI 776333.00 Awarded Level:Federal
Grant: #1R01NS140155-01 Investigators:Demel, Stacie; Sawyer, Russell; Walsh, Kyle; Woo, Daniel -08-31-2028 National Institute of Neurological Disorders and Stroke Metabolomics of ICH recovery (METABOL-ICH) Role:Collaborator 0.00 Hold Level:Federal
Grant: #CUMC# TBD / R01HL173606 Investigators:Vagal, Achala; Walsh, Kyle; Woo, Daniel 07-20-2025 -04-30-2030 National Heart, Lung and Blood Institute Functional coaGulation and HemosTasis after IntraCerebral Hemorrhage (FIGHT ICH) Role:PI 245233.00 Hold Level:Federal
Publications
Peer Reviewed Publications
Walsh, Kyle B; Marion, Miranda C; Li, Dengfeng; Ainsworth, Hannah C; Zinnia, Amy; Zhang, Xiang; Demel, Stacie L; Williamson, Brady; Roh, David J; Campbell, Robert; Denorme, Frederik; Woo, Daniel; Langefeld, Carl D (2025. ) Neutrophil degranulation is increased at seven days after human intracerebral hemorrhage, but not at 72 h, and correlates with decreased miR-3613 and miR-3690.BMC neurology, , 25 (1 ) ,388 More Information
Becker, Christopher J; Patel, Janaki; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Alwell, Kathleen S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Jasne, Adam S; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Kissela, Brett; Kleindorfer, Dawn (2025. ) Association Between Food Desert Residence and Ischemic Stroke Risk: A Population-Based Study.Neurology, , 105 (5 ) ,e213979 More Information
Wechsler, Paul M; Mistry, Eva A; Sucharew, Heidi; Robinson, David J; Stanton, Robert; de Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Demel, Stacie L; Coleman, Elisheva R; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Haverbusch, Mary; Alwell, Kathleen; Woo, Daniel; Kleindorfer, Dawn O; Kissela, Brett M (2025. ) Differences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status.Journal of the American Heart Association, , 14 (11 ) ,e040499 More Information
Robinson, David J; Ding, Lili; Howard, George; Stanton, Robert J; Khoury, Jane; Sucharew, Heidi; Haverbusch, Mary; Nobel, Lisa; Khatri, Pooja; Adeoye, Opeolu; Broderick, Joseph P; Ferioli, Simona; Mackey, Jason; Woo, Daniel; Rios La Rosa, Felipa De Los; Flaherty, Matthew; Slavin, Sabreena; Star, Michael; Martini, Sharyl R; Demel, Stacie; Walsh, Kyle B; Coleman, Elisheva; Jasne, Adam S; Mistry, Eva A; Kleindorfer, Dawn; Kissela, Brett (2024. ) Temporal Trends and Racial Disparities in Long-Term Survival After Stroke.Neurology, , 103 (3 ) ,e209653 More Information
Mistry, Eva A; Khoury, Jane C; Kleindorfer, Dawn O; Kissela, Brett M; Alwell, Kathleen S; Jasne, Adam S; Ferioli, Simona; De Los Rios La Rosa, Felipe; Coleman, Elisheva; Demel, Stacie L; Walsh, Kyle B; Slavin, Sabreena J; Star, Michael; Haverbusch, Mary; Mackey, Jason; Woo, Daniel; Aziz, Yasmin N; Heldner, Mirjam R; Fischer, Urs; Jadhav, Ashutosh P; Jovin, Tudor G; Albers, Gregory W; Nogueira, Raul G; Khatri, Pooja (2024. ) Projections of Endovascular Therapy-Eligible Patients With Stroke for the US Population.Stroke, , 55 (8 ) ,2011-2019 More Information
Becker, Christopher J; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Jasne, Adam S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Flaherty, Matthew L; Martini, Sharyl R; Kissela, Brett; Kleindorfer, Dawn (2024. ) Impact of Poverty on Stroke Recurrence: A Population-Based Study.Neurology, , 102 (11 ) ,e209423 More Information
Madsen, Tracy E; Ding, Lili; Khoury, Jane C; Haverbusch, Mary; Woo, Daniel; Ferioli, Simona; De Los Rios La Rosa, Felipe; Martini, Sharyl R; Adeoye, Opeolu; Khatri, Pooja; Flaherty, Matthew L; Mackey, Jason; Mistry, Eva A; Demel, Stacie; Coleman, Elisheva; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Broderick, Joseph P; Kissela, Brett; Kleindorfer, Dawn O (2024. ) Trends Over Time in Stroke Incidence by Race in the Greater Cincinnati Northern Kentucky Stroke Study.Neurology, , 102 (3 ) ,e208077 More Information
Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P (2022. ) MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration.Medicine, , 101 (40 ) ,e30854 More Information
Ng, Yisi; Qi, Wenjing; King, Nicolas Kon Kam; Christianson, Thomas; Krishnamoorthy, Vijay; Shah, Shreyansh; Divani, Afshin; Bettin, Margaret; Coleman, Elisheva R; Flaherty, Matthew L; Walsh, Kyle B; Testai, Fernando D; McCauley, Jacob L; Gilkerson, Lee A; Langefeld, Carl D; Behymer, Tyler Paul; Woo, Daniel; James, Michael L (2022. ) Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage.Stroke and vascular neurology, , 7 (5 ) ,367-374 More Information
O'Connell, Grant C; Walsh, Kyle B; Smothers, Christine G; Ruksakulpiwat, Suebsarn; Armentrout, Bethany L; Winkelman, Chris; Milling, Truman J; Warach, Steven J; Barr, Taura L (2022. ) Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts.BMC neurology, , 22 (1 ) ,206 More Information
Robinson, David; Van Sanford, Carson; Kwon, Soo Young; Coleman, Elisheva; Sekar, Padmini; Murphy, Ryan; Flaherty, Matthew L; Demel, Stacie L; Aziz, Yasmin; Moomaw, Charles J; Haverbusch, Mary; Khoury, Jane; Adeoye, Opeolu; Walsh, Kyle B; Broderick, Joseph P; Woo, Daniel (2022. ) What is the median volume of intracerebral hemorrhage and is it changing?.International journal of stroke : official journal of the International Stroke Society, , 17 (5 ) ,576-582 More Information
Walsh, Kyle B; Zimmerman, Kip D; Zhang, Xiang; Demel, Stacie L; Luo, Yu; Langefeld, Carl D; Wohleb, Eric; Schulert, Grant; Woo, Daniel; Adeoye, Opeolu (2021. ) miR-181a Mediates Inflammatory Gene Expression After Intracerebral Hemorrhage: An Integrated Analysis of miRNA-seq and mRNA-seq in a Swine ICH Model.Journal of molecular neuroscience : MN, , 71 (9 ) ,1802-1814 More Information
Hsiao, Jessica; Sayles, Emily; Antzoulatos, Eleni; Stanton, Robert J; Sucharew, Heidi; Broderick, Joseph P; Demel, Stacie L; Flaherty, Matthew L; Grossman, Aaron W; Kircher, Charles; Kreitzer, Natalie; Peariso, Katrina; Prestigiacomo, Charles J; Shirani, Peyman; Walsh, Kyle B; Lampton, Holly; Adeoye, Opeolu; Khatri, Pooja (2020. ) Effect of COVID-19 on Emergent Stroke Care: A Regional Experience.Stroke, , 51 (9 ) ,e2111-e2114 More Information
Farrant, Mary; Easton, J Donald; Adelman, Eric E; Cucchiara, Brett L; Barsan, William G; Tillman, Holly J; Elm, Jordan J; Kim, Anthony S; Lindblad, Anne S; Palesch, Yuko Y; Zhao, Wenle; Pauls, Keith; Walsh, Kyle B; Martí-Fàbregas, Joan; Bernstein, Richard A; Johnston, S Claiborne (2019. ) Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis.JAMA network open, , 2 (9 ) ,e1910769 More Information
Walsh, Kyle B (2019. ) Non-invasive sensor technology for prehospital stroke diagnosis: Current status and future directions.International journal of stroke : official journal of the International Stroke Society, , 14 (6 ) ,592-602 More Information
Leasure, Audrey C; Qureshi, Adnan I; Murthy, Santosh B; Kamel, Hooman; Goldstein, Joshua N; Walsh, Kyle B; Woo, Daniel; Shi, Fu-Dong; Huttner, Hagen B; Ziai, Wendy C; Hanley, Daniel F; Matouk, Charles C; Sansing, Lauren H; Falcone, Guido J; Sheth, Kevin N (2019. ) Intensive Blood Pressure Reduction and Perihematomal Edema Expansion in Deep Intracerebral Hemorrhage.Stroke, , 50 (8 ) ,2016-2022 More Information
Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu (2019. ) Intracerebral Hemorrhage Induces Inflammatory Gene Expression in Peripheral Blood: Global Transcriptional Profiling in Intracerebral Hemorrhage Patients.DNA and cell biology, , 38 (7 ) ,660-669 More Information
O'Connell, Grant C; Stafford, Phillip; Walsh, Kyle B; Adeoye, Opeolu; Barr, Taura L (2019. ) High-Throughput Profiling of Circulating Antibody Signatures for Stroke Diagnosis Using Small Volumes of Whole Blood.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, , 16 (3 ) ,868-877 More Information
Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu (2019. ) Intracerebral hemorrhage induces monocyte-related gene expression within six hours: Global transcriptional profiling in swine ICH.Metabolic brain disease, , 34 (3 ) ,763-774 More Information
Napier, Jarred; Rose, Lucas; Adeoye, Opeolu; Hooker, Edmond; Walsh, Kyle B (2019. ) Modulating acute neuroinflammation in intracerebral hemorrhage: the potential promise of currently approved medications for multiple sclerosis.Immunopharmacology and immunotoxicology, , 41 (1 ) ,7-15 More Information
O'Connell, Grant C; Walsh, Kyle B; Burrage, Emily; Adeoye, Opeolu; Chantler, Paul D; Barr, Taura L (2018. ) High-throughput profiling of the circulating proteome suggests sexually dimorphic corticosteroid signaling following ischemic stroke.Physiological genomics, , 50 (10 ) ,876-883 More Information
Walsh, Kyle B; Campos, Begoña; Hart, Kimberly; Thakar, Charuhas; Adeoye, Opeolu (2017. ) M2 Monocyte Microparticles Are Increased in Intracerebral Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , 26 (10 ) ,2369-2375 More Information
Wolcott, Zoe; Batra, Ayush; Bevers, Matthew B; Sastre, Cristina; Khoury, Jane; Sperling, Matthew; Meyer, Brett C; Walsh, Kyle B; Adeoye, Opeolu; Broderick, Joseph P; Kimberly, W Taylor (2017. ) Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke.Annals of clinical and translational neurology, , 4 (8 ) ,553-563 More Information
Nahan, Keaton S; Walsh, Kyle B; Adeoye, Opeolu; Landero-Figueroa, Julio A (2017. ) The metal and metalloprotein profile of human plasma as biomarkers for stroke diagnosis.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), , 42 ,81-91 More Information
Walsh, Kyle B; Woo, Daniel; Sekar, Padmini; Osborne, Jennifer; Moomaw, Charles J; Langefeld, Carl D; Adeoye, Opeolu (2016. ) Untreated Hypertension: A Powerful Risk Factor for Lobar and Nonlobar Intracerebral Hemorrhage in Whites, Blacks, and Hispanics.Circulation, , 134 (19 ) ,1444-1452 More Information
Walsh, Kyle B; Hart, Kimberly; Roll, Susan; Sperling, Matthew; Unruh, Dusten; Davidson, W Sean; Lindsell, Christopher J; Adeoye, Opeolu (2016. ) Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , 25 (6 ) ,1360-5 More Information
Walsh, Kyle B; Woo, Daniel; Adeoye, Opeolu (2015. ) Response to Letter Regarding Article, "Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage".Stroke, , 46 (11 ) ,e244 More Information
Walsh, Kyle B; Sekar, Padmini; Langefeld, Carl D; Moomaw, Charles J; Elkind, Mitchell S V; Boehme, Amelia K; James, Michael L; Osborne, Jennifer; Sheth, Kevin N; Woo, Daniel; Adeoye, Opeolu (2015. ) Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage.Stroke, , 46 (8 ) ,2302-4 More Information
Stanton, Robert J; Aziz, Yasmin N; Sucharew, Heidi; Haverbusch, Mary; Robinson, David J; Coleman, Elisheva; De Los Rios La Rosa, Felipe; Demel, Stacie; Ferioli, Simona; Mackey, Jason; Jasne, Adam; Madsen, Tracy E; Mistry, Eva; Slavin, Sabreena; Star, Michael; Walsh, Kyle; Woo, Daniel; Khatri, Pooja; Broderick, Joseph; Kissela, Brett; Kleindorfer, Dawn O (2024. ) Clinical Trial Exclusion Criteria Affect Trial Inclusivity by Race and Sex.Journal of the American Heart Association, , 13 (13 ) ,e035102 More Information
Contact Information
Academic - University of Cincinnati College of Medicine
Department of Emergency Medicine
Cincinnati
Ohio, 45267-0769
Phone: 513-558-5281
Fax: 513-558-5791
Kyle.Walsh@uc.edu