Kyle Walsh

Kyle Walsh, MD

Associate Professor of Clinical

Attending Physician Emergency Medicine, Neurocritical Care, UC Stroke Team

University of Cincinnati College of Medicine
Department of Emergency Medicine
231 Albert Sabin Way, MSB 1654
Cincinnati , Ohio 45267-0769
Phone 513-558-5281
Fax 513-558-5791
Email Kyle.Walsh@uc.edu

Education

Bachelor's Degree: Michigan State University (Biology)

Medical Degree: Michigan State University

Residency Training: University of Cincinnati 2015 (Emergency Medicine)

Certifications

American Board of Emergency Medicine (Certification Date: 05-16-2016 )

United Council for Neurologic Subspecialties (Certification Date: 12-01-2019 )

Clinical Interests

Emergency Medicine

Stroke

Acute Stroke

Cerebrovascular Disorders

Hemorrhagic Stroke

Intracranial Hemorrhages

Ischemic Stroke

Neurogenic Inflammation

Stroke, including Hemorrhagic Stroke and Ischemic Stroke

Stroke-Related Cognitive Dysfunction

Vascular Cognitive Impairment

Specialities

Emergency Medicine

Neurocritical Care

Research and Practice Interests

Research Support

Grant: #SBIR Phase II / NSF 1632270 Investigators:Hartings, Jed; Walsh, Kyle 06-01-2017 -05-31-2018 National Science Foundation SBIR Phase II: Novel Device for Monitoring Brain Hemorrhage Using Radio Waves Role:PI $127,396.00 Active Level:Federal

Grant: #SBIR PHIIB / IIP-1632270-001 Investigators:Walsh, Kyle 06-22-2020 -06-22-2021 National Science Foundation Technology Enhancement for Commercial Partnerships; NSF# 1632270 Role:PI $32,342.00 Awarded Level:Federal

Grant: #20TPA35490044 Investigators:Walsh, Kyle 01-01-2021 -12-31-2023 American Heart Association - National Chapter Serial RNA-seq in Acute ICH Patients: Association with 90-day Outcomes and Identification of Novel Treatment Targets Role:PI $100,000.00 Awarded Level:Private Non-Profit

Grant: #SENSE-006 Investigators:Walsh, Kyle 10-01-2021 -10-01-2024 Sense Diagnostics, LLC A Retrospective Evaluation of SENSE-003's Impact on Routine Care Role:PI 0.00 Hold Level:Industry

Investigators:Walsh, Kyle 02-18-2022 -02-17-2025 Sense Diagnostics, LLC A Prospective, Non-randomized, Sequentially-enrolled, Multi-center, Phase II Study to Evaluate the SENSE Device's Ability to Detect and Monitor Traumatic Brain Injury Role:PI 64705.50 Hold Level:Industry

Grant: #R01NS128425 Investigators:Esfandiari, Leyla; Langevin, Scott; Walsh, Kyle; Woo, Daniel 07-19-2022 -06-30-2027 National Institute of Neurological Disorders and Stroke CAPSTONE: Central And Peripheral STrOke inflammatioN with Exosomes Role:PI 776333.00 Awarded Level:Federal

Grant: #1R01NS140155-01 Investigators:Demel, Stacie; Sawyer, Russell; Walsh, Kyle; Woo, Daniel -08-31-2028 National Institute of Neurological Disorders and Stroke Metabolomics of ICH recovery (METABOL-ICH) Role:Collaborator 0.00 Hold Level:Federal

Grant: #CUMC# TBD / R01HL173606 Investigators:Vagal, Achala; Walsh, Kyle; Woo, Daniel 07-20-2025 -04-30-2030 National Heart, Lung and Blood Institute Functional coaGulation and HemosTasis after IntraCerebral Hemorrhage (FIGHT ICH) Role:PI 245233.00 Hold Level:Federal

Publications

Peer Reviewed Publications

Walsh, Kyle B; Marion, Miranda C; Li, Dengfeng; Ainsworth, Hannah C; Zinnia, Amy; Zhang, Xiang; Demel, Stacie L; Williamson, Brady; Roh, David J; Campbell, Robert; Denorme, Frederik; Woo, Daniel; Langefeld, Carl D  (2025). Neutrophil degranulation is increased at seven days after human intracerebral hemorrhage, but not at 72 h, and correlates with decreased miR-3613 and miR-3690. BMC neurology, 25 (1) , 388More Information

Becker, Christopher J; Patel, Janaki; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Alwell, Kathleen S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Jasne, Adam S; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Kissela, Brett; Kleindorfer, Dawn  (2025). Association Between Food Desert Residence and Ischemic Stroke Risk: A Population-Based Study. Neurology, 105 (5) , e213979More Information

Wechsler, Paul M; Mistry, Eva A; Sucharew, Heidi; Robinson, David J; Stanton, Robert; de Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Demel, Stacie L; Coleman, Elisheva R; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Haverbusch, Mary; Alwell, Kathleen; Woo, Daniel; Kleindorfer, Dawn O; Kissela, Brett M  (2025). Differences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status. Journal of the American Heart Association, 14 (11) , e040499More Information

Robinson, David J; Ding, Lili; Howard, George; Stanton, Robert J; Khoury, Jane; Sucharew, Heidi; Haverbusch, Mary; Nobel, Lisa; Khatri, Pooja; Adeoye, Opeolu; Broderick, Joseph P; Ferioli, Simona; Mackey, Jason; Woo, Daniel; Rios La Rosa, Felipa De Los; Flaherty, Matthew; Slavin, Sabreena; Star, Michael; Martini, Sharyl R; Demel, Stacie; Walsh, Kyle B; Coleman, Elisheva; Jasne, Adam S; Mistry, Eva A; Kleindorfer, Dawn; Kissela, Brett  (2024). Temporal Trends and Racial Disparities in Long-Term Survival After Stroke. Neurology, 103 (3) , e209653More Information

Mistry, Eva A; Khoury, Jane C; Kleindorfer, Dawn O; Kissela, Brett M; Alwell, Kathleen S; Jasne, Adam S; Ferioli, Simona; De Los Rios La Rosa, Felipe; Coleman, Elisheva; Demel, Stacie L; Walsh, Kyle B; Slavin, Sabreena J; Star, Michael; Haverbusch, Mary; Mackey, Jason; Woo, Daniel; Aziz, Yasmin N; Heldner, Mirjam R; Fischer, Urs; Jadhav, Ashutosh P; Jovin, Tudor G; Albers, Gregory W; Nogueira, Raul G; Khatri, Pooja  (2024). Projections of Endovascular Therapy-Eligible Patients With Stroke for the US Population. Stroke, 55 (8) , 2011-2019More Information

Becker, Christopher J; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Jasne, Adam S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Flaherty, Matthew L; Martini, Sharyl R; Kissela, Brett; Kleindorfer, Dawn  (2024). Impact of Poverty on Stroke Recurrence: A Population-Based Study. Neurology, 102 (11) , e209423More Information

Madsen, Tracy E; Ding, Lili; Khoury, Jane C; Haverbusch, Mary; Woo, Daniel; Ferioli, Simona; De Los Rios La Rosa, Felipe; Martini, Sharyl R; Adeoye, Opeolu; Khatri, Pooja; Flaherty, Matthew L; Mackey, Jason; Mistry, Eva A; Demel, Stacie; Coleman, Elisheva; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Broderick, Joseph P; Kissela, Brett; Kleindorfer, Dawn O  (2024). Trends Over Time in Stroke Incidence by Race in the Greater Cincinnati Northern Kentucky Stroke Study. Neurology, 102 (3) , e208077More Information

Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P  (2022). MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration. Medicine, 101 (40) , e30854More Information

Ng, Yisi; Qi, Wenjing; King, Nicolas Kon Kam; Christianson, Thomas; Krishnamoorthy, Vijay; Shah, Shreyansh; Divani, Afshin; Bettin, Margaret; Coleman, Elisheva R; Flaherty, Matthew L; Walsh, Kyle B; Testai, Fernando D; McCauley, Jacob L; Gilkerson, Lee A; Langefeld, Carl D; Behymer, Tyler Paul; Woo, Daniel; James, Michael L  (2022). Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage. Stroke and vascular neurology, 7 (5) , 367-374More Information

O'Connell, Grant C; Walsh, Kyle B; Smothers, Christine G; Ruksakulpiwat, Suebsarn; Armentrout, Bethany L; Winkelman, Chris; Milling, Truman J; Warach, Steven J; Barr, Taura L  (2022). Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts. BMC neurology, 22 (1) , 206More Information

Robinson, David; Van Sanford, Carson; Kwon, Soo Young; Coleman, Elisheva; Sekar, Padmini; Murphy, Ryan; Flaherty, Matthew L; Demel, Stacie L; Aziz, Yasmin; Moomaw, Charles J; Haverbusch, Mary; Khoury, Jane; Adeoye, Opeolu; Walsh, Kyle B; Broderick, Joseph P; Woo, Daniel  (2022). What is the median volume of intracerebral hemorrhage and is it changing?. International journal of stroke : official journal of the International Stroke Society, 17 (5) , 576-582More Information

Walsh, Kyle B; Zimmerman, Kip D; Zhang, Xiang; Demel, Stacie L; Luo, Yu; Langefeld, Carl D; Wohleb, Eric; Schulert, Grant; Woo, Daniel; Adeoye, Opeolu  (2021). miR-181a Mediates Inflammatory Gene Expression After Intracerebral Hemorrhage: An Integrated Analysis of miRNA-seq and mRNA-seq in a Swine ICH Model. Journal of molecular neuroscience : MN, 71 (9) , 1802-1814More Information

Hsiao, Jessica; Sayles, Emily; Antzoulatos, Eleni; Stanton, Robert J; Sucharew, Heidi; Broderick, Joseph P; Demel, Stacie L; Flaherty, Matthew L; Grossman, Aaron W; Kircher, Charles; Kreitzer, Natalie; Peariso, Katrina; Prestigiacomo, Charles J; Shirani, Peyman; Walsh, Kyle B; Lampton, Holly; Adeoye, Opeolu; Khatri, Pooja  (2020). Effect of COVID-19 on Emergent Stroke Care: A Regional Experience. Stroke, 51 (9) , e2111-e2114More Information

Farrant, Mary; Easton, J Donald; Adelman, Eric E; Cucchiara, Brett L; Barsan, William G; Tillman, Holly J; Elm, Jordan J; Kim, Anthony S; Lindblad, Anne S; Palesch, Yuko Y; Zhao, Wenle; Pauls, Keith; Walsh, Kyle B; Martí-Fàbregas, Joan; Bernstein, Richard A; Johnston, S Claiborne  (2019). Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis. JAMA network open, 2 (9) , e1910769More Information

Walsh, Kyle B  (2019). Non-invasive sensor technology for prehospital stroke diagnosis: Current status and future directions. International journal of stroke : official journal of the International Stroke Society, 14 (6) , 592-602More Information

Leasure, Audrey C; Qureshi, Adnan I; Murthy, Santosh B; Kamel, Hooman; Goldstein, Joshua N; Walsh, Kyle B; Woo, Daniel; Shi, Fu-Dong; Huttner, Hagen B; Ziai, Wendy C; Hanley, Daniel F; Matouk, Charles C; Sansing, Lauren H; Falcone, Guido J; Sheth, Kevin N  (2019). Intensive Blood Pressure Reduction and Perihematomal Edema Expansion in Deep Intracerebral Hemorrhage. Stroke, 50 (8) , 2016-2022More Information

Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu  (2019). Intracerebral Hemorrhage Induces Inflammatory Gene Expression in Peripheral Blood: Global Transcriptional Profiling in Intracerebral Hemorrhage Patients. DNA and cell biology, 38 (7) , 660-669More Information

O'Connell, Grant C; Stafford, Phillip; Walsh, Kyle B; Adeoye, Opeolu; Barr, Taura L  (2019). High-Throughput Profiling of Circulating Antibody Signatures for Stroke Diagnosis Using Small Volumes of Whole Blood. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 16 (3) , 868-877More Information

Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu  (2019). Intracerebral hemorrhage induces monocyte-related gene expression within six hours: Global transcriptional profiling in swine ICH. Metabolic brain disease, 34 (3) , 763-774More Information

Napier, Jarred; Rose, Lucas; Adeoye, Opeolu; Hooker, Edmond; Walsh, Kyle B  (2019). Modulating acute neuroinflammation in intracerebral hemorrhage: the potential promise of currently approved medications for multiple sclerosis. Immunopharmacology and immunotoxicology, 41 (1) , 7-15More Information

O'Connell, Grant C; Walsh, Kyle B; Burrage, Emily; Adeoye, Opeolu; Chantler, Paul D; Barr, Taura L  (2018). High-throughput profiling of the circulating proteome suggests sexually dimorphic corticosteroid signaling following ischemic stroke. Physiological genomics, 50 (10) , 876-883More Information

Walsh, Kyle B; Campos, Begoña; Hart, Kimberly; Thakar, Charuhas; Adeoye, Opeolu  (2017). M2 Monocyte Microparticles Are Increased in Intracerebral Hemorrhage. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 26 (10) , 2369-2375More Information

Wolcott, Zoe; Batra, Ayush; Bevers, Matthew B; Sastre, Cristina; Khoury, Jane; Sperling, Matthew; Meyer, Brett C; Walsh, Kyle B; Adeoye, Opeolu; Broderick, Joseph P; Kimberly, W Taylor  (2017). Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke. Annals of clinical and translational neurology, 4 (8) , 553-563More Information

Nahan, Keaton S; Walsh, Kyle B; Adeoye, Opeolu; Landero-Figueroa, Julio A  (2017). The metal and metalloprotein profile of human plasma as biomarkers for stroke diagnosis. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 42, 81-91More Information

Walsh, Kyle B; Woo, Daniel; Sekar, Padmini; Osborne, Jennifer; Moomaw, Charles J; Langefeld, Carl D; Adeoye, Opeolu  (2016). Untreated Hypertension: A Powerful Risk Factor for Lobar and Nonlobar Intracerebral Hemorrhage in Whites, Blacks, and Hispanics. Circulation, 134 (19) , 1444-1452More Information

Walsh, Kyle B; Hart, Kimberly; Roll, Susan; Sperling, Matthew; Unruh, Dusten; Davidson, W Sean; Lindsell, Christopher J; Adeoye, Opeolu  (2016). Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 25 (6) , 1360-5More Information

Walsh, Kyle B; Woo, Daniel; Adeoye, Opeolu  (2015). Response to Letter Regarding Article, "Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage". Stroke, 46 (11) , e244More Information

Walsh, Kyle B; Sekar, Padmini; Langefeld, Carl D; Moomaw, Charles J; Elkind, Mitchell S V; Boehme, Amelia K; James, Michael L; Osborne, Jennifer; Sheth, Kevin N; Woo, Daniel; Adeoye, Opeolu  (2015). Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage. Stroke, 46 (8) , 2302-4More Information

Stanton, Robert J; Aziz, Yasmin N; Sucharew, Heidi; Haverbusch, Mary; Robinson, David J; Coleman, Elisheva; De Los Rios La Rosa, Felipe; Demel, Stacie; Ferioli, Simona; Mackey, Jason; Jasne, Adam; Madsen, Tracy E; Mistry, Eva; Slavin, Sabreena; Star, Michael; Walsh, Kyle; Woo, Daniel; Khatri, Pooja; Broderick, Joseph; Kissela, Brett; Kleindorfer, Dawn O  (2024). Clinical Trial Exclusion Criteria Affect Trial Inclusivity by Race and Sex. Journal of the American Heart Association, 13 (13) , e035102More Information

Dwamena, Francesca C; Mavis, Brian; Holmes-Rovner, Margaret; Walsh, Kyle B; Loyson, Amber C  (2009). Teaching medical interviewing to patients: the other side of the encounter. Patient education and counseling, 76 (3) , 380-4More Information

Walsh, Kyle B; Toledo, Alexander H; Rivera-Chavez, Fernando A; Lopez-Neblina, Fernando; Toledo-Pereyra, Luis H  (2009). Inflammatory mediators of liver ischemia-reperfusion injury. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 7 (2) , 78-93

Contact Information

Academic - University of Cincinnati College of Medicine
Department of Emergency Medicine
Cincinnati   Ohio, 45267-0769
Phone: 513-558-5281
Fax: 513-558-5791
Kyle.Walsh@uc.edu