
Kyle Walsh, MD
Associate Professor of Clinical
Attending Physician Emergency Medicine, Neurocritical Care, UC Stroke Team
University of Cincinnati College of Medicine
Department of Emergency Medicine
231 Albert Sabin Way, MSB 1654
Cincinnati , Ohio 45267-0769
Phone 513-558-5281
Fax 513-558-5791
Email Kyle.Walsh@uc.edu
Education
Bachelor's Degree: Michigan State University (Biology)
Medical Degree: Michigan State University
Residency Training: University of Cincinnati 2015 (Emergency Medicine)
Certifications
American Board of Emergency Medicine (Certification Date: 05-16-2016 )
United Council for Neurologic Subspecialties (Certification Date: 12-01-2019 )
Clinical Interests
Emergency Medicine
Stroke
Acute Stroke
Cerebrovascular Disorders
Hemorrhagic Stroke
Intracranial Hemorrhages
Ischemic Stroke
Neurogenic Inflammation
Stroke, including Hemorrhagic Stroke and Ischemic Stroke
Stroke-Related Cognitive Dysfunction
Vascular Cognitive Impairment
Specialities
Emergency Medicine
Neurocritical Care
Research and Practice Interests
Research Support
Grant: #SBIR Phase II / NSF 1632270 Investigators:Hartings, Jed; Walsh, Kyle 06-01-2017 -05-31-2018 National Science Foundation SBIR Phase II: Novel Device for Monitoring Brain Hemorrhage Using Radio Waves Role:PI $127,396.00 Active Level:Federal
Grant: #SBIR PHIIB / IIP-1632270-001 Investigators:Walsh, Kyle 06-22-2020 -06-22-2021 National Science Foundation Technology Enhancement for Commercial Partnerships; NSF# 1632270 Role:PI $32,342.00 Awarded Level:Federal
Grant: #20TPA35490044 Investigators:Walsh, Kyle 01-01-2021 -12-31-2023 American Heart Association - National Chapter Serial RNA-seq in Acute ICH Patients: Association with 90-day Outcomes and Identification of Novel Treatment Targets Role:PI $100,000.00 Awarded Level:Private Non-Profit
Grant: #SENSE-006 Investigators:Walsh, Kyle 10-01-2021 -10-01-2024 Sense Diagnostics, LLC A Retrospective Evaluation of SENSE-003's Impact on Routine Care Role:PI 0.00 Hold Level:Industry
Investigators:Walsh, Kyle 02-18-2022 -02-17-2025 Sense Diagnostics, LLC A Prospective, Non-randomized, Sequentially-enrolled, Multi-center, Phase II Study to Evaluate the SENSE Device's Ability to Detect and Monitor Traumatic Brain Injury Role:PI 64705.50 Hold Level:Industry
Grant: #R01NS128425 Investigators:Esfandiari, Leyla; Langevin, Scott; Walsh, Kyle; Woo, Daniel 07-19-2022 -06-30-2027 National Institute of Neurological Disorders and Stroke CAPSTONE: Central And Peripheral STrOke inflammatioN with Exosomes Role:PI 776333.00 Awarded Level:Federal
Grant: #1R01NS140155-01 Investigators:Demel, Stacie; Sawyer, Russell; Walsh, Kyle; Woo, Daniel -08-31-2028 National Institute of Neurological Disorders and Stroke Metabolomics of ICH recovery (METABOL-ICH) Role:Collaborator 0.00 Hold Level:Federal
Grant: #CUMC# TBD / R01HL173606 Investigators:Vagal, Achala; Walsh, Kyle; Woo, Daniel 07-20-2025 -04-30-2030 National Heart, Lung and Blood Institute Functional coaGulation and HemosTasis after IntraCerebral Hemorrhage (FIGHT ICH) Role:PI 245233.00 Hold Level:Federal
Publications
Peer Reviewed Publications
Walsh, Kyle B; Marion, Miranda C; Li, Dengfeng; Ainsworth, Hannah C; Zinnia, Amy; Zhang, Xiang; Demel, Stacie L; Williamson, Brady; Roh, David J; Campbell, Robert; Denorme, Frederik; Woo, Daniel; Langefeld, Carl D (2025). Neutrophil degranulation is increased at seven days after human intracerebral hemorrhage, but not at 72 h, and correlates with decreased miR-3613 and miR-3690. BMC neurology, 25 (1) , 388More Information
Becker, Christopher J; Patel, Janaki; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Alwell, Kathleen S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Jasne, Adam S; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Kissela, Brett; Kleindorfer, Dawn (2025). Association Between Food Desert Residence and Ischemic Stroke Risk: A Population-Based Study. Neurology, 105 (5) , e213979More Information
Wechsler, Paul M; Mistry, Eva A; Sucharew, Heidi; Robinson, David J; Stanton, Robert; de Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Demel, Stacie L; Coleman, Elisheva R; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Haverbusch, Mary; Alwell, Kathleen; Woo, Daniel; Kleindorfer, Dawn O; Kissela, Brett M (2025). Differences in In-Hospital and Post-Discharge Ischemic Stroke Care According to Prestroke Functional Status. Journal of the American Heart Association, 14 (11) , e040499More Information
Robinson, David J; Ding, Lili; Howard, George; Stanton, Robert J; Khoury, Jane; Sucharew, Heidi; Haverbusch, Mary; Nobel, Lisa; Khatri, Pooja; Adeoye, Opeolu; Broderick, Joseph P; Ferioli, Simona; Mackey, Jason; Woo, Daniel; Rios La Rosa, Felipa De Los; Flaherty, Matthew; Slavin, Sabreena; Star, Michael; Martini, Sharyl R; Demel, Stacie; Walsh, Kyle B; Coleman, Elisheva; Jasne, Adam S; Mistry, Eva A; Kleindorfer, Dawn; Kissela, Brett (2024). Temporal Trends and Racial Disparities in Long-Term Survival After Stroke. Neurology, 103 (3) , e209653More Information
Mistry, Eva A; Khoury, Jane C; Kleindorfer, Dawn O; Kissela, Brett M; Alwell, Kathleen S; Jasne, Adam S; Ferioli, Simona; De Los Rios La Rosa, Felipe; Coleman, Elisheva; Demel, Stacie L; Walsh, Kyle B; Slavin, Sabreena J; Star, Michael; Haverbusch, Mary; Mackey, Jason; Woo, Daniel; Aziz, Yasmin N; Heldner, Mirjam R; Fischer, Urs; Jadhav, Ashutosh P; Jovin, Tudor G; Albers, Gregory W; Nogueira, Raul G; Khatri, Pooja (2024). Projections of Endovascular Therapy-Eligible Patients With Stroke for the US Population. Stroke, 55 (8) , 2011-2019More Information
Becker, Christopher J; Sucharew, Heidi; Robinson, David; Stamm, Brian; Royan, Regina; Nobel, Lisa; Stanton, Robert J; Jasne, Adam S; Woo, Daniel; De Los Rios La Rosa, Felipe; Mackey, Jason; Ferioli, Simona; Mistry, Eva A; Demel, Stacie; Haverbusch, Mary; Coleman, Elisheva; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Flaherty, Matthew L; Martini, Sharyl R; Kissela, Brett; Kleindorfer, Dawn (2024). Impact of Poverty on Stroke Recurrence: A Population-Based Study. Neurology, 102 (11) , e209423More Information
Madsen, Tracy E; Ding, Lili; Khoury, Jane C; Haverbusch, Mary; Woo, Daniel; Ferioli, Simona; De Los Rios La Rosa, Felipe; Martini, Sharyl R; Adeoye, Opeolu; Khatri, Pooja; Flaherty, Matthew L; Mackey, Jason; Mistry, Eva A; Demel, Stacie; Coleman, Elisheva; Jasne, Adam; Slavin, Sabreena; Walsh, Kyle B; Star, Michael; Broderick, Joseph P; Kissela, Brett; Kleindorfer, Dawn O (2024). Trends Over Time in Stroke Incidence by Race in the Greater Cincinnati Northern Kentucky Stroke Study. Neurology, 102 (3) , e208077More Information
Pounders, Jonathan; Hill, Emily J; Hooper, Destiny; Zhang, Xiang; Biesiada, Jacek; Kuhnell, Damaris; Greenland, Hannah L; Esfandiari, Leyla; Timmerman, Emerlee; Foster, Forrest; Wang, Chenran; Walsh, Kyle B; Shatz, Rhonna; Woo, Daniel; Medvedovic, Mario; Langevin, Scott; Sawyer, Russell P (2022). MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration. Medicine, 101 (40) , e30854More Information
Ng, Yisi; Qi, Wenjing; King, Nicolas Kon Kam; Christianson, Thomas; Krishnamoorthy, Vijay; Shah, Shreyansh; Divani, Afshin; Bettin, Margaret; Coleman, Elisheva R; Flaherty, Matthew L; Walsh, Kyle B; Testai, Fernando D; McCauley, Jacob L; Gilkerson, Lee A; Langefeld, Carl D; Behymer, Tyler Paul; Woo, Daniel; James, Michael L (2022). Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage. Stroke and vascular neurology, 7 (5) , 367-374More Information
O'Connell, Grant C; Walsh, Kyle B; Smothers, Christine G; Ruksakulpiwat, Suebsarn; Armentrout, Bethany L; Winkelman, Chris; Milling, Truman J; Warach, Steven J; Barr, Taura L (2022). Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts. BMC neurology, 22 (1) , 206More Information
Robinson, David; Van Sanford, Carson; Kwon, Soo Young; Coleman, Elisheva; Sekar, Padmini; Murphy, Ryan; Flaherty, Matthew L; Demel, Stacie L; Aziz, Yasmin; Moomaw, Charles J; Haverbusch, Mary; Khoury, Jane; Adeoye, Opeolu; Walsh, Kyle B; Broderick, Joseph P; Woo, Daniel (2022). What is the median volume of intracerebral hemorrhage and is it changing?. International journal of stroke : official journal of the International Stroke Society, 17 (5) , 576-582More Information
Walsh, Kyle B; Zimmerman, Kip D; Zhang, Xiang; Demel, Stacie L; Luo, Yu; Langefeld, Carl D; Wohleb, Eric; Schulert, Grant; Woo, Daniel; Adeoye, Opeolu (2021). miR-181a Mediates Inflammatory Gene Expression After Intracerebral Hemorrhage: An Integrated Analysis of miRNA-seq and mRNA-seq in a Swine ICH Model. Journal of molecular neuroscience : MN, 71 (9) , 1802-1814More Information
Hsiao, Jessica; Sayles, Emily; Antzoulatos, Eleni; Stanton, Robert J; Sucharew, Heidi; Broderick, Joseph P; Demel, Stacie L; Flaherty, Matthew L; Grossman, Aaron W; Kircher, Charles; Kreitzer, Natalie; Peariso, Katrina; Prestigiacomo, Charles J; Shirani, Peyman; Walsh, Kyle B; Lampton, Holly; Adeoye, Opeolu; Khatri, Pooja (2020). Effect of COVID-19 on Emergent Stroke Care: A Regional Experience. Stroke, 51 (9) , e2111-e2114More Information
Farrant, Mary; Easton, J Donald; Adelman, Eric E; Cucchiara, Brett L; Barsan, William G; Tillman, Holly J; Elm, Jordan J; Kim, Anthony S; Lindblad, Anne S; Palesch, Yuko Y; Zhao, Wenle; Pauls, Keith; Walsh, Kyle B; Martí-Fàbregas, Joan; Bernstein, Richard A; Johnston, S Claiborne (2019). Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: A Secondary Analysis. JAMA network open, 2 (9) , e1910769More Information
Walsh, Kyle B (2019). Non-invasive sensor technology for prehospital stroke diagnosis: Current status and future directions. International journal of stroke : official journal of the International Stroke Society, 14 (6) , 592-602More Information
Leasure, Audrey C; Qureshi, Adnan I; Murthy, Santosh B; Kamel, Hooman; Goldstein, Joshua N; Walsh, Kyle B; Woo, Daniel; Shi, Fu-Dong; Huttner, Hagen B; Ziai, Wendy C; Hanley, Daniel F; Matouk, Charles C; Sansing, Lauren H; Falcone, Guido J; Sheth, Kevin N (2019). Intensive Blood Pressure Reduction and Perihematomal Edema Expansion in Deep Intracerebral Hemorrhage. Stroke, 50 (8) , 2016-2022More Information
Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu (2019). Intracerebral Hemorrhage Induces Inflammatory Gene Expression in Peripheral Blood: Global Transcriptional Profiling in Intracerebral Hemorrhage Patients. DNA and cell biology, 38 (7) , 660-669More Information
O'Connell, Grant C; Stafford, Phillip; Walsh, Kyle B; Adeoye, Opeolu; Barr, Taura L (2019). High-Throughput Profiling of Circulating Antibody Signatures for Stroke Diagnosis Using Small Volumes of Whole Blood. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 16 (3) , 868-877More Information
Walsh, Kyle B; Zhang, Xiang; Zhu, Xiaoting; Wohleb, Eric; Woo, Daniel; Lu, Long; Adeoye, Opeolu (2019). Intracerebral hemorrhage induces monocyte-related gene expression within six hours: Global transcriptional profiling in swine ICH. Metabolic brain disease, 34 (3) , 763-774More Information
Napier, Jarred; Rose, Lucas; Adeoye, Opeolu; Hooker, Edmond; Walsh, Kyle B (2019). Modulating acute neuroinflammation in intracerebral hemorrhage: the potential promise of currently approved medications for multiple sclerosis. Immunopharmacology and immunotoxicology, 41 (1) , 7-15More Information
O'Connell, Grant C; Walsh, Kyle B; Burrage, Emily; Adeoye, Opeolu; Chantler, Paul D; Barr, Taura L (2018). High-throughput profiling of the circulating proteome suggests sexually dimorphic corticosteroid signaling following ischemic stroke. Physiological genomics, 50 (10) , 876-883More Information
Walsh, Kyle B; Campos, Begoña; Hart, Kimberly; Thakar, Charuhas; Adeoye, Opeolu (2017). M2 Monocyte Microparticles Are Increased in Intracerebral Hemorrhage. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 26 (10) , 2369-2375More Information
Wolcott, Zoe; Batra, Ayush; Bevers, Matthew B; Sastre, Cristina; Khoury, Jane; Sperling, Matthew; Meyer, Brett C; Walsh, Kyle B; Adeoye, Opeolu; Broderick, Joseph P; Kimberly, W Taylor (2017). Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke. Annals of clinical and translational neurology, 4 (8) , 553-563More Information
Nahan, Keaton S; Walsh, Kyle B; Adeoye, Opeolu; Landero-Figueroa, Julio A (2017). The metal and metalloprotein profile of human plasma as biomarkers for stroke diagnosis. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 42, 81-91More Information
Walsh, Kyle B; Woo, Daniel; Sekar, Padmini; Osborne, Jennifer; Moomaw, Charles J; Langefeld, Carl D; Adeoye, Opeolu (2016). Untreated Hypertension: A Powerful Risk Factor for Lobar and Nonlobar Intracerebral Hemorrhage in Whites, Blacks, and Hispanics. Circulation, 134 (19) , 1444-1452More Information
Walsh, Kyle B; Hart, Kimberly; Roll, Susan; Sperling, Matthew; Unruh, Dusten; Davidson, W Sean; Lindsell, Christopher J; Adeoye, Opeolu (2016). Apolipoprotein A-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 25 (6) , 1360-5More Information
Walsh, Kyle B; Woo, Daniel; Adeoye, Opeolu (2015). Response to Letter Regarding Article, "Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage". Stroke, 46 (11) , e244More Information
Walsh, Kyle B; Sekar, Padmini; Langefeld, Carl D; Moomaw, Charles J; Elkind, Mitchell S V; Boehme, Amelia K; James, Michael L; Osborne, Jennifer; Sheth, Kevin N; Woo, Daniel; Adeoye, Opeolu (2015). Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage. Stroke, 46 (8) , 2302-4More Information
Stanton, Robert J; Aziz, Yasmin N; Sucharew, Heidi; Haverbusch, Mary; Robinson, David J; Coleman, Elisheva; De Los Rios La Rosa, Felipe; Demel, Stacie; Ferioli, Simona; Mackey, Jason; Jasne, Adam; Madsen, Tracy E; Mistry, Eva; Slavin, Sabreena; Star, Michael; Walsh, Kyle; Woo, Daniel; Khatri, Pooja; Broderick, Joseph; Kissela, Brett; Kleindorfer, Dawn O (2024). Clinical Trial Exclusion Criteria Affect Trial Inclusivity by Race and Sex. Journal of the American Heart Association, 13 (13) , e035102More Information
Dwamena, Francesca C; Mavis, Brian; Holmes-Rovner, Margaret; Walsh, Kyle B; Loyson, Amber C (2009). Teaching medical interviewing to patients: the other side of the encounter. Patient education and counseling, 76 (3) , 380-4More Information
Walsh, Kyle B; Toledo, Alexander H; Rivera-Chavez, Fernando A; Lopez-Neblina, Fernando; Toledo-Pereyra, Luis H (2009). Inflammatory mediators of liver ischemia-reperfusion injury. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 7 (2) , 78-93
Contact Information
Academic - University of Cincinnati College of Medicine
Department of Emergency Medicine
Cincinnati
Ohio, 45267-0769
Phone: 513-558-5281
Fax: 513-558-5791
Kyle.Walsh@uc.edu