Sing Sing Way , MD,PhD

I work in infectious disease pediatrics because I love kids and I love taking care of them. Patients are the most vulnerable during infancy and early life development, which means they need advocates for their health.

My research interests include infectious diseases, reproductive biology, developmental biology and immunology. I was attracted to my research when I became frustrated with not being able to tell parents why their child became sick and how to prevent their illness in the future.

There are several questions that my colleagues and I are attempting to solve, such as:

• Does infection during pregnancy lead to pregnancy impediments?
• How does the immune system differentiate between helpful commensal microbes and pathogens?
• Why are infants more likely to become infected?
• Why are some infections more acute in certain people?
• Why are women who are pregnant more prone toward infections?
• Why do some people get infections while others do not?

Grant: #BWF 1011031 Investigators:Ball, William; Way, Sing_Sing 10-01-2012 -09-30-2017 Burroughs Wellcome Fund Maternal Regulatory T cells Control the Immune Pathogenesis of Prenatal Infection Role:Collaborator $500,000.00 Active Level:Private Non-Profit

Peer Reviewed Publications

Xin, Lijun; Jiang, Tony T; Kinder, Jeremy M; Ertelt, James M; Way, Sing Sing (2015. ) Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice.Aging cell, , More Information

Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing (2015. ) Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells.Cell, , 162 (3 ) ,505-15 More Information

Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing (2015. ) CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage.The Journal of clinical investigation, , 125 (4 ) ,1713-25 More Information

PrabhuDas, Mercy; Bonney, Elizabeth; Caron, Kathleen; Dey, Sudhansu; Erlebacher, Adrian; Fazleabas, Asgerally; Fisher, Susan; Golos, Thaddeus; Matzuk, Martin; McCune, Joseph M; Mor, Gil; Schulz, Laura; Soares, Michael; Spencer, Thomas; Strominger, Jack; Way, Sing Sing; Yoshinaga, Koji (2015. ) Immune mechanisms at the maternal-fetal interface: perspectives and challenges.Nature immunology, , 16 (4 ) ,328-34 More Information

Nanton, Minelva R; Lee, Seung-Joo; Atif, Shaikh M; Nuccio, Sean-Paul; Taylor, Justin J; Bäumler, Andreas J; Way, Sing Sing; McSorley, Stephen J (2015. ) Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development.European journal of immunology, , 45 (2 ) ,428-41 More Information

Drummond, Rebecca A; Wallace, Carol; Reid, Delyth M; Way, Sing Sing; Kaplan, Daniel H; Brown, Gordon D (2014. ) Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis.Journal of immunology (Baltimore, Md. : 1950), , 193 (11 ) ,5381-5 More Information

Clark, Dayna R; Chaturvedi, Vandana; Kinder, Jeremy M; Jiang, Tony T; Xin, Lijun; Ertelt, James M; Way, Sing Sing (2014. ) Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy.Cellular & molecular immunology, , 11 (6 ) ,595-605 More Information

Xin, Lijun; Jiang, Tony T; Chaturvedi, Vandana; Kinder, Jeremy M; Ertelt, James M; Rowe, Jared H; Steinbrecher, Kris A; Way, Sing Sing (2014. ) Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2.Proceedings of the National Academy of Sciences of the United States of America, , 111 (29 ) ,10672-7 More Information

Jiang, Tony T; Chaturvedi, Vandana; Ertelt, James M; Kinder, Jeremy M; Clark, Dayna R; Valent, Amy M; Xin, Lijun; Way, Sing Sing (2014. ) Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications.Journal of immunology (Baltimore, Md. : 1950), , 192 (11 ) ,4949-56 More Information

Xin, Lijun; Ertelt, James M; Rowe, Jared H; Jiang, Tony T; Kinder, Jeremy M; Chaturvedi, Vandana; Elahi, Shokrollah; Way, Sing Sing (2014. ) Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal loss.Journal of immunology (Baltimore, Md. : 1950), , 192 (7 ) ,2970-4 More Information

Kinder, Jeremy M; Jiang, Tony T; Clark, Dayna R; Chaturvedi, Vandana; Xin, Lijun; Ertelt, James M; Way, Sing Sing Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism?.Chimerism, , 5 (1 ) ,16-9 More Information

Elahi, Shokrollah; Ertelt, James M; Kinder, Jeremy M; Jiang, Tony T; Zhang, Xuzhe; Xin, Lijun; Chaturvedi, Vandana; Strong, Beverly S; Qualls, Joseph E; Steinbrecher, Kris A; Kalfa, Theodosia A; Shaaban, Aimen F; Way, Sing Sing (2013. ) Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection.Nature, , 504 (7478 ) ,158-62 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2013. ) Regulatory T cells and the immune pathogenesis of prenatal infection.Reproduction (Cambridge, England), , 146 (6 ) ,R191-203 More Information

Ertelt, James M; Buyukbasaran, Esra Z; Jiang, Tony T; Rowe, Jared H; Xin, Lijun; Way, Sing Sing (2013. ) B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells.Journal of leukocyte biology, , 94 (2 ) ,367-76 More Information

Shafiani, Shahin; Dinh, Crystal; Ertelt, James M; Moguche, Albanus O; Siddiqui, Imran; Smigiel, Kate S; Sharma, Pawan; Campbell, Daniel J; Way, Sing Sing; Urdahl, Kevin B (2013. ) Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12.Immunity, , 38 (6 ) ,1261-70 More Information

Tubo, Noah J; Pagán, Antonio J; Taylor, Justin J; Nelson, Ryan W; Linehan, Jonathan L; Ertelt, James M; Huseby, Eric S; Way, Sing Sing; Jenkins, Marc K (2013. ) Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.Cell, , 153 (4 ) ,785-96 More Information

Burnaevskiy, Nikolay; Fox, Thomas G; Plymire, Daniel A; Ertelt, James M; Weigele, Bethany A; Selyunin, Andrey S; Way, Sing Sing; Patrie, Steven M; Alto, Neal M (2013. ) Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.Nature, , 496 (7443 ) ,106-9 More Information

Nanton, Minelva R; Way, Sing Sing; Shlomchik, Mark J; McSorley, Stephen J (2012. ) Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretion.Journal of immunology (Baltimore, Md. : 1950), , 189 (12 ) ,5503-7 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2012. ) Pregnancy imprints regulatory memory that sustains anergy to fetal antigen.Nature, , 490 (7418 ) ,102-6 More Information

Rowe, Jared H; Ertelt, James M; Way, Sing Sing (2012. ) Innate IFN-? is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection.Journal of immunology (Baltimore, Md. : 1950), , 189 (2 ) ,876-84 More Information

Rowe, Jared H; Ertelt, James M; Way, Sing Sing (2012. ) Foxp3(+) regulatory T cells, immune stimulation and host defence against infection.Immunology, , 136 (1 ) ,1-10 More Information

Kanistanon, Duangjit; Powell, Daniel A; Hajjar, Adeline M; Pelletier, Mark R; Cohen, Ilana E; Way, Sing Sing; Skerrett, Shawn J; Wang, Xiaoyuan; Raetz, Christian R H; Ernst, Robert K (2012. ) Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.Infection and immunity, , 80 (3 ) ,943-51 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2012. ) Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance.PLoS pathogens, , 8 (8 ) ,e1002873 More Information

Ertelt, James M; Johanns, Tanner M; Mysz, Margaret A; Nanton, Minelva R; Rowe, Jared H; Aguilera, Marijo N; Way, Sing Sing (2011. ) Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection.Immunology, , 134 (4 ) ,487-97 More Information

Ertelt, James M; Rowe, Jared H; Mysz, Margaret A; Singh, Charanjeet; Roychowdhury, Monika; Aguilera, Marijo N; Way, Sing Sing (2011. ) Foxp3+ regulatory T cells impede the priming of protective CD8+ T cells.Journal of immunology (Baltimore, Md. : 1950), , 187 (5 ) ,2569-77 More Information

Rudd, Brian D; Venturi, Vanessa; Li, Gang; Samadder, Partha; Ertelt, James M; Way, Sing Sing; Davenport, Miles P; Nikolich-Žugich, Janko (2011. ) Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.Proceedings of the National Academy of Sciences of the United States of America, , 108 (33 ) ,13694-9 More Information

Rowe, Jared H; Ertelt, James M; Aguilera, Marijo N; Farrar, Michael A; Way, Sing Sing (2011. ) Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens.Cell host & microbe, , 10 (1 ) ,54-64 More Information

Johanns, Tanner M; Law, Calvin Y; Kalekar, Lokeshchandra A; O'Donnell, Hope; Ertelt, James M; Rowe, Jared H; Way, Sing Sing (2011. ) Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection.Microbes and infection / Institut Pasteur, , 13 (4 ) ,322-30 More Information

Han, Jin-Young; Hanson, David C; Way, Sing Sing (2011. ) Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child.The Pediatric infectious disease journal, , 30 (3 ) ,266-8 More Information

Ertelt, James M; Johanns, Tanner M; Rowe, Jared H; Way, Sing Sing (2010. ) Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production.Immunology, , 131 (2 ) ,183-91 More Information

Curtis, Meredith M; Rowell, Emily; Shafiani, Shahin; Negash, Amina; Urdahl, Kevin B; Wilson, Christopher B; Way, Sing Sing (2010. ) Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle.Cell host & microbe, , 8 (2 ) ,163-73 More Information

Johanns, Tanner M; Ertelt, James M; Rowe, Jared H; Way, Sing Sing (2010. ) Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection.PLoS pathogens, , 6 (8 ) ,e1001043 More Information

Winstead, Colleen J; Reilly, Cavan S; Moon, James J; Jenkins, Marc K; Hamilton, Sara E; Jameson, Stephen C; Way, Sing Sing; Khoruts, Alexander (2010. ) CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia.Journal of immunology (Baltimore, Md. : 1950), , 184 (9 ) ,4749-60 More Information

Rudd, Brian D; Venturi, Vanessa; Smithey, Megan J; Way, Sing Sing; Davenport, Miles P; Nikolich-Zugich, Janko (2010. ) Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.Journal of immunology (Baltimore, Md. : 1950), , 184 (6 ) ,2958-65 More Information

Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Rowe, Jared H; Avant, Ross A; Way, Sing Sing (2010. ) Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency.Journal of immunology (Baltimore, Md. : 1950), , 184 (2 ) ,869-76 More Information

Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Way, Sing Sing (2009. ) Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge.Immunology, , 128 (1 Suppl ) ,e471-8 More Information

Curtis, Meredith M; Way, Sing Sing; Wilson, Christopher B (2009. ) IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.Journal of immunology (Baltimore, Md. : 1950), , 183 (1 ) ,381-7 More Information

Ertelt, James M; Rowe, Jared H; Johanns, Tanner M; Lai, Joseph C; McLachlan, James B; Way, Sing Sing (2009. ) Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection.Journal of immunology (Baltimore, Md. : 1950), , 182 (5 ) ,3032-8 More Information

Curtis, Meredith M; Way, Sing Sing (2009. ) Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens.Immunology, , 126 (2 ) ,177-85 More Information

Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Way, Sing Sing (2008. ) PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), , 180 (11 ) ,7553-7

Orgun, Nural N; Mathis, Meredith A; Wilson, Christopher B; Way, Sing Sing (2008. ) Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. Journal of immunology (Baltimore, Md. : 1950), , 180 (6 ) ,4109-15

Orgun, Nural N; Way, Sing Sing (2008. ) A critical role for phospholipase C in protective immunity conferred by listeriolysin O-deficient Listeria monocytogenes.Microbial pathogenesis, , 44 (2 ) ,159-63 More Information

Muller, William J; Orgun, Nural N; Dong, Lichun; Koelle, David M; Huang, Meei-Li; Way, Sing Sing (2008. ) Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2.Archives of virology, , 153 (6 ) ,1165-9 More Information

Asplin, Iain R; Carl, David J; Way, Sing Sing; Jones, Amanda L (2008. ) Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus.Microbial pathogenesis, , 44 (1 ) ,43-51 More Information

Orr, Mark T; Orgun, Nural N; Wilson, Christopher B; Way, Sing Sing (2007. ) Cutting edge: recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. Journal of immunology (Baltimore, Md. : 1950), , 178 (8 ) ,4731-5

Way, Sing Sing; Havenar-Daughton, Colin; Kolumam, Ganesh A; Orgun, Nural N; Murali-Krishna, Kaja (2007. ) IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), , 178 (7 ) ,4498-505

Kollmann, Tobias R; Reikie, Brian; Blimkie, Darren; Way, Sing Sing; Hajjar, Adeline M; Arispe, Kiea; Shaulov, Angela; Wilson, Christopher B (2007. ) Induction of protective immunity to Listeria monocytogenes in neonates. Journal of immunology (Baltimore, Md. : 1950), , 178 (6 ) ,3695-701

Way, Sing Sing; Wilson, Christopher B (2005. ) The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo.Infection and immunity, , 73 (9 ) ,6151-3 More Information

Way, Sing Sing; Wilson, Christopher B (2004. ) Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. Journal of immunology (Baltimore, Md. : 1950), , 173 (10 ) ,5918-22

Darveau, Richard P; Pham, Thu-Thao T; Lemley, Kayde; Reife, Robert A; Bainbridge, Brian W; Coats, Stephen R; Howald, William N; Way, Sing Sing; Hajjar, Adeline M (2004. ) Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4.Infection and immunity, , 72 (9 ) ,5041-51 More Information

Kollmann, Tobias R; Way, Sing Sing; Harowicz, Heidi L; Hajjar, Adeline M; Wilson, Christopher B (2004. ) Deficient MHC class I cross-presentation of soluble antigen by murine neonatal dendritic cells.Blood, , 103 (11 ) ,4240-2 More Information

Way, Sing Sing; Thompson, Lucas J; Lopes, Jared E; Hajjar, Adeline M; Kollmann, Tobias R; Freitag, Nancy E; Wilson, Christopher B (2004. ) Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cellular microbiology, , 6 (3 ) ,235-42

Way, Sing Sing; Kollmann, Tobias R; Hajjar, Adeline M; Wilson, Christopher B (2003. ) Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88. Journal of immunology (Baltimore, Md. : 1950), , 171 (2 ) ,533-7

Shetron-Rama, Lynne M; Mueller, Kimberly; Bravo, Juan M; Bouwer, H G Archie; Way, Sing Sing; Freitag, Nancy E (2003. ) Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Molecular microbiology, , 48 (6 ) ,1537-51

Almanan, Maha; Raynor, Jana; Ogunsulire, Ireti; Malyshkina, Anna; Mukherjee, Shibabrata; Hummel, Sarah A; Ingram, Jennifer T; Saini, Ankur; Xie, Markus M; Alenghat, Theresa; Way, Sing Sing; Deepe, George S; Divanovic, Senad; Singh, Harinder; Miraldi, Emily; Zajac, Allan J; Dent, Alexander L; Hölscher, Christoph; Chougnet, Claire; Hildeman, David A (2020. ) IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression.Science advances, , 6 (31 ) ,eabb0806 More Information

Burg, Ashley R; Erickson, John J; Turner, Lucien H; Pham, Giang; Kinder, Jeremy M; Way, Sing Sing (2020. ) Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes.Journal of immunology (Baltimore, Md. : 1950), , 205 (2 ) ,447-453 More Information

Kinder, Jeremy M; Turner, Lucien H; Stelzer, Ina A; Miller-Handley, Hilary; Burg, Ashley; Shao, Tzu-Yu; Pham, Giang; Way, Sing Sing (2020. ) CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization.Cell reports, , 31 (12 ) ,107784 More Information

Yang, Li; Shivakumar, Pranavkumar; Kinder, Jeremy; Way, Sing Sing; Donnelly, Bryan; Mourya, Reena; Luo, Zhenhua; Bezerra, Jorge A (2020. ) Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells.JCI insight, , 5 (11 ) , More Information

Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton (2020. ) Mouse models of neutropenia reveal progenitor-stage-specific defects.Nature, , 582 (7810 ) ,109-114 More Information

Kollmann, Tobias R; Marchant, Arnaud; Way, Sing Sing (2020. ) Vaccination strategies to enhance immunity in neonates.Science (New York, N.Y.), , 368 (6491 ) ,612-615 More Information

Chen, Yee-Shiuan; Chen, Iuan-Bor; Pham, Giang; Shao, Tzu-Yu; Bangar, Hansraj; Way, Sing Sing; Haslam, David B (2020. ) IL-17-producing ?? T cells protect against Clostridium difficile infection.The Journal of clinical investigation, , 130 (5 ) ,2377-2390 More Information

Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L (2019. ) Fungus Among Us: The Frenemies Within.Trends in immunology, , 40 (6 ) ,469-471 More Information

Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K (2019. ) TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.Journal of immunology (Baltimore, Md. : 1950), , 202 (9 ) ,2535-2545 More Information

Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing (2019. ) Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses.Cell host & microbe, , 25 (3 ) ,404-417.e6 More Information

Deshmukh, Hitesh; Way, Sing Sing (2019. ) Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications.Annual review of pathology, , 14 ,185-210 More Information

DiToro, Daniel; Winstead, Colleen J; Pham, Duy; Witte, Steven; Andargachew, Rakieb; Singer, Jeffrey R; Wilson, C Garrett; Zindl, Carlene L; Luther, Rita J; Silberger, Daniel J; Weaver, Benjamin T; Kolawole, E Motunrayo; Martinez, Ryan J; Turner, Henrietta; Hatton, Robin D; Moon, James J; Way, Sing Sing; Evavold, Brian D; Weaver, Casey T (2018. ) Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.Science (New York, N.Y.), , 361 (6407 ) , More Information

Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing (2018. ) Declining responsiveness to influenza vaccination with progression of human pregnancy.Vaccine, , 36 (31 ) ,4734-4741 More Information

Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-Žugich, Janko; Kuhns, Michael S (2018. ) A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.PloS one, , 13 (6 ) ,e0198354 More Information

Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M (2018. ) Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages.PLoS pathogens, , 14 (5 ) ,e1007060 More Information

Zhou, Jordan Z; Way, Sing Sing; Chen, Kang (2018. ) Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018).Trends in immunology, , 39 (4 ) ,355 More Information

Zhou, Jordan Z; Way, Sing Sing; Chen, Kang (2018. ) Immunology of the Uterine and Vaginal Mucosae.Trends in immunology, , 39 (4 ) ,302-314 More Information

Jiang, Tony T; Shao, Tzu-Yu; Ang, W X Gladys; Kinder, Jeremy M; Turner, Lucien H; Pham, Giang; Whitt, Jordan; Alenghat, Theresa; Way, Sing Sing (2017. ) Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria.Cell host & microbe, , 22 (6 ) ,809-816.e4 More Information

Lange, Shannon M; McKell, Melanie C; Schmidt, Stephanie M; Hossfeld, Austin P; Chaturvedi, Vandana; Kinder, Jeremy M; McAlees, Jaclyn W; Lewkowich, Ian P; Way, Sing Sing; Turner, Joanne; Qualls, Joseph E (2017. ) l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung.Frontiers in immunology, , 8 ,1561 More Information

Turner, Lucien H; Kinder, Jeremy M; Wilburn, Adrienne; D'Mello, Rahul J; Braunlin, Makayla R; Jiang, Tony T; Pham, Giang; Way, Sing Sing (2017. ) Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection.PLoS pathogens, , 13 (11 ) ,e1006684 More Information

Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing (2017. ) Reply: Breastfeeding-related maternal microchimerism.Nature reviews. Immunology, , 17 (11 ) ,730-1 More Information

Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing (2017. ) Immunological implications of pregnancy-induced microchimerism.Nature reviews. Immunology, , 17 (8 ) ,483-494 More Information

Navabi, Nazanin; Whitt, Jordan; Wu, Shu-En; Woo, Vivienne; Moncivaiz, Jessica; Jordan, Michael B; Vallance, Bruce A; Way, Sing Sing; Alenghat, Theresa (2017. ) Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation.Cell reports, , 19 (6 ) ,1165-1175 More Information

Cappelletti, Monica; Presicce, Pietro; Lawson, Matthew J; Chaturvedi, Vandana; Stankiewicz, Traci E; Vanoni, Simone; Harley, Isaac Tw; McAlees, Jaclyn W; Giles, Daniel A; Moreno-Fernandez, Maria E; Rueda, Cesar M; Senthamaraikannan, Paranth; Sun, Xiaofei; Karns, Rebekah; Hoebe, Kasper; Janssen, Edith M; Karp, Christopher L; Hildeman, David A; Hogan, Simon P; Kallapur, Suhas G; Chougnet, Claire A; Way, Sing Sing; Divanovic, Senad (2017. ) Type I interferons regulate susceptibility to inflammation-induced preterm birth.JCI insight, , 2 (5 ) ,e91288 More Information

Jiang, Tony T; Martinov, Tijana; Xin, Lijun; Kinder, Jeremy M; Spanier, Justin A; Fife, Brian T; Way, Sing Sing (2016. ) Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity.Cell reports, , 17 (7 ) ,1783-1794 More Information

Johnson, Lexus R; Weizman, Orr-El; Rapp, Moritz; Way, Sing Sing; Sun, Joseph C (2016. ) Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge.Cell reports, , 17 (3 ) ,636-644 More Information

Kinder, Jeremy M; Jiang, Tony T; Way, Sing Sing (2016. ) Offspring's Tolerance of Mother Goes Viral.Immunity, , 44 (5 ) ,1085-7 More Information

Rosenblum, Michael D; Way, Sing Sing; Abbas, Abul K (2016. ) Regulatory T cell memory.Nature reviews. Immunology, , 16 (2 ) ,90-101 More Information

Carpenter, Stephen M; Nunes-Alves, Cláudio; Booty, Matthew G; Way, Sing Sing; Behar, Samuel M (2016. ) A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis.PLoS pathogens, , 12 (1 ) ,e1005380 More Information

Legoux, Francois P; Lim, Jong-Baeck; Cauley, Andrew W; Dikiy, Stanislav; Ertelt, James; Mariani, Thomas J; Sparwasser, Tim; Way, Sing Sing; Moon, James J (2015. ) CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.Immunity, , 43 (5 ) ,896-908 More Information

Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing (2015. ) Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'.Chimerism, , 6 (1-2 ) ,8-20 More Information

Erickson, John J; Archer-Hartmann, Stephanie; Yarawsky, Alexander E; Miller, Jeanette L C; Seveau, Stephanie; Shao, Tzu-Yu; Severance, Ashley L; Miller-Handley, Hilary; Wu, Yuehong; Pham, Giang; Wasik, Brian R; Parrish, Colin R; Hu, Yueh-Chiang; Lau, Joseph T Y; Azadi, Parastoo; Herr, Andrew B; Way, Sing Sing (2022. ) Pregnancy enables antibody protection against intracellular infection.Nature, , 606 (7915 ) ,769-775 More Information

Shao, Tzu-Yu; Kakade, Pallavi; Witchley, Jessica N; Frazer, Corey; Murray, Kathryn L; Ene, Iuliana V; Haslam, David B; Hagan, Thomas; Noble, Suzanne M; Bennett, Richard J; Way, Sing Sing (2022. ) Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity.Cell reports, , 39 (7 ) ,110837 More Information

Severance, Ashley L; Kinder, Jeremy M; Xin, Lijun; Burg, Ashley R; Shao, Tzu-Yu; Pham, Giang; Tilburgs, Tamara; Goodman, Wendy A; Mesiano, Sam; Way, Sing Sing (2022. ) Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells.iScience, , 25 (6 ) ,104400 More Information

McDaniel, Margaret M; Chawla, Amanpreet Singh; Jain, Aakanksha; Meibers, Hannah E; Saha, Irene; Gao, Yajing; Jain, Viral; Roskin, Krishna; Way, Sing Sing; Pasare, Chandrashekhar (2022. ) Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells.Science immunology, , 7 (67 ) ,eabk0182 More Information

Alarcon, Pablo C; Damen, Michelle S M A; Madan, Rajat; Deepe, George S; Spearman, Paul; Way, Sing Sing; Divanovic, Senad (2021. ) Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution.Mucosal immunology, , 14 (6 ) ,1224-1234 More Information

Chen, Didi; Burford, Wesley B; Pham, Giang; Zhang, Lishu; Alto, Laura T; Ertelt, James M; Winter, Maria G; Winter, Sebastian E; Way, Sing Sing; Alto, Neal M (2021. ) Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism.Cell host & microbe, , 29 (10 ) ,1531-1544.e9 More Information

Cappelletti, Monica; Presicce, Pietro; Feiyang, Ma; Senthamaraikannan, Paranthaman; Miller, Lisa A; Pellegrini, Matteo; Sim, Myung S; Jobe, Alan H; Divanovic, Senad; Way, Sing Sing; Chougnet, Claire A; Kallapur, Suhas G (2021. ) The induction of preterm labor in rhesus macaques is determined by the  strength of immune response to intrauterine infection.PLoS biology, , 19 (9 ) ,e3001385 More Information

Miller-Handley, Hilary; Erickson, John J; Gregory, Emily J; Prasanphanich, Nina Salinger; Shao, Tzu-Yu; Way, Sing Sing (2021. ) Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility.Transplant infectious disease : an official journal of the Transplantation Society, , 23 (4 ) ,e13655 More Information

Gregory, Emily J; Liu, James; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing (2021. ) Epidemiology of Pregnancy Complications Through the Lens of Immunological Memory.Frontiers in immunology, , 12 ,693189 More Information

Prasanphanich, Nina Salinger; Gregory, Emily J; Erickson, John J; Miller-Handley, Hilary; Kinder, Jeremy M; Way, Sing Sing (2021. ) Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy.mBio, , 12 (1 ) , More Information

Zhang, Jizhou; Wu, Qingqing; Johnson, Courtney B; Pham, Giang; Kinder, Jeremy M; Olsson, Andre; Slaughter, Anastasiya; May, Margot; Weinhaus, Benjamin; D'Alessandro, Angelo; Engel, James Douglas; Jiang, Jean X; Kofron, J Matthew; Huang, L Frank; Prasath, V B Surya; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton; Lucas, Daniel (2021. ) In situ mapping identifies distinct vascular niches for myelopoiesis.Nature, , 590 (7846 ) ,457-462 More Information

Bianchi, Diana W; Khosrotehrani, Kiarash; Way, Sing Sing; MacKenzie, Tippi C; Bajema, Ingeborg; O'Donoghue, Keelin (2021. ) Forever Connected: The Lifelong Biological Consequences of Fetomaternal and Maternofetal Microchimerism.Clinical chemistry, , 67 (2 ) ,351-362 More Information

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