Sing Sing  Way

Sing Sing Way , MD, PhD

Professor-Affiliate

CCHMC S Building
240 Albert Sabin Way
Cincinnati, Ohio 45229
Phone 513-636-7603
Email singsing.way@cchmc.org

Research Support

Grant: #BWF 1011031 Investigators:Ball, William; Way, Sing_Sing 10-01-2012 -09-30-2017 Burroughs Wellcome Fund Maternal Regulatory T cells Control the Immune Pathogenesis of Prenatal Infection Role:Collaborator $500,000.00 Active Level:Private Non-Profit

Publications

Peer Reviewed Publications

Xin, Lijun; Jiang, Tony T; Kinder, Jeremy M; Ertelt, James M; Way, Sing Sing (2015. ) Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice.Aging cell, , More Information

Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing (2015. ) Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells.Cell, , 162 (3 ) ,505-15 More Information

Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing (2015. ) CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage.The Journal of clinical investigation, , 125 (4 ) ,1713-25 More Information

PrabhuDas, Mercy; Bonney, Elizabeth; Caron, Kathleen; Dey, Sudhansu; Erlebacher, Adrian; Fazleabas, Asgerally; Fisher, Susan; Golos, Thaddeus; Matzuk, Martin; McCune, Joseph M; Mor, Gil; Schulz, Laura; Soares, Michael; Spencer, Thomas; Strominger, Jack; Way, Sing Sing; Yoshinaga, Koji (2015. ) Immune mechanisms at the maternal-fetal interface: perspectives and challenges.Nature immunology, , 16 (4 ) ,328-34 More Information

Nanton, Minelva R; Lee, Seung-Joo; Atif, Shaikh M; Nuccio, Sean-Paul; Taylor, Justin J; Bäumler, Andreas J; Way, Sing Sing; McSorley, Stephen J (2015. ) Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development.European journal of immunology, , 45 (2 ) ,428-41 More Information

Drummond, Rebecca A; Wallace, Carol; Reid, Delyth M; Way, Sing Sing; Kaplan, Daniel H; Brown, Gordon D (2014. ) Cutting edge: Failure of antigen-specific CD4+ T cell recruitment to the kidney during systemic candidiasis.Journal of immunology (Baltimore, Md. : 1950), , 193 (11 ) ,5381-5 More Information

Clark, Dayna R; Chaturvedi, Vandana; Kinder, Jeremy M; Jiang, Tony T; Xin, Lijun; Ertelt, James M; Way, Sing Sing (2014. ) Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy.Cellular & molecular immunology, , 11 (6 ) ,595-605 More Information

Xin, Lijun; Jiang, Tony T; Chaturvedi, Vandana; Kinder, Jeremy M; Ertelt, James M; Rowe, Jared H; Steinbrecher, Kris A; Way, Sing Sing (2014. ) Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2.Proceedings of the National Academy of Sciences of the United States of America, , 111 (29 ) ,10672-7 More Information

Jiang, Tony T; Chaturvedi, Vandana; Ertelt, James M; Kinder, Jeremy M; Clark, Dayna R; Valent, Amy M; Xin, Lijun; Way, Sing Sing (2014. ) Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications.Journal of immunology (Baltimore, Md. : 1950), , 192 (11 ) ,4949-56 More Information

Xin, Lijun; Ertelt, James M; Rowe, Jared H; Jiang, Tony T; Kinder, Jeremy M; Chaturvedi, Vandana; Elahi, Shokrollah; Way, Sing Sing (2014. ) Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal loss.Journal of immunology (Baltimore, Md. : 1950), , 192 (7 ) ,2970-4 More Information

Kinder, Jeremy M; Jiang, Tony T; Clark, Dayna R; Chaturvedi, Vandana; Xin, Lijun; Ertelt, James M; Way, Sing Sing Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism?.Chimerism, , 5 (1 ) ,16-9 More Information

Elahi, Shokrollah; Ertelt, James M; Kinder, Jeremy M; Jiang, Tony T; Zhang, Xuzhe; Xin, Lijun; Chaturvedi, Vandana; Strong, Beverly S; Qualls, Joseph E; Steinbrecher, Kris A; Kalfa, Theodosia A; Shaaban, Aimen F; Way, Sing Sing (2013. ) Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection.Nature, , 504 (7478 ) ,158-62 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2013. ) Regulatory T cells and the immune pathogenesis of prenatal infection.Reproduction (Cambridge, England), , 146 (6 ) ,R191-203 More Information

Ertelt, James M; Buyukbasaran, Esra Z; Jiang, Tony T; Rowe, Jared H; Xin, Lijun; Way, Sing Sing (2013. ) B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells.Journal of leukocyte biology, , 94 (2 ) ,367-76 More Information

Shafiani, Shahin; Dinh, Crystal; Ertelt, James M; Moguche, Albanus O; Siddiqui, Imran; Smigiel, Kate S; Sharma, Pawan; Campbell, Daniel J; Way, Sing Sing; Urdahl, Kevin B (2013. ) Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12.Immunity, , 38 (6 ) ,1261-70 More Information

Tubo, Noah J; Pagán, Antonio J; Taylor, Justin J; Nelson, Ryan W; Linehan, Jonathan L; Ertelt, James M; Huseby, Eric S; Way, Sing Sing; Jenkins, Marc K (2013. ) Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.Cell, , 153 (4 ) ,785-96 More Information

Burnaevskiy, Nikolay; Fox, Thomas G; Plymire, Daniel A; Ertelt, James M; Weigele, Bethany A; Selyunin, Andrey S; Way, Sing Sing; Patrie, Steven M; Alto, Neal M (2013. ) Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.Nature, , 496 (7443 ) ,106-9 More Information

Nanton, Minelva R; Way, Sing Sing; Shlomchik, Mark J; McSorley, Stephen J (2012. ) Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretion.Journal of immunology (Baltimore, Md. : 1950), , 189 (12 ) ,5503-7 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2012. ) Pregnancy imprints regulatory memory that sustains anergy to fetal antigen.Nature, , 490 (7418 ) ,102-6 More Information

Rowe, Jared H; Ertelt, James M; Way, Sing Sing (2012. ) Innate IFN-? is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection.Journal of immunology (Baltimore, Md. : 1950), , 189 (2 ) ,876-84 More Information

Rowe, Jared H; Ertelt, James M; Way, Sing Sing (2012. ) Foxp3(+) regulatory T cells, immune stimulation and host defence against infection.Immunology, , 136 (1 ) ,1-10 More Information

Kanistanon, Duangjit; Powell, Daniel A; Hajjar, Adeline M; Pelletier, Mark R; Cohen, Ilana E; Way, Sing Sing; Skerrett, Shawn J; Wang, Xiaoyuan; Raetz, Christian R H; Ernst, Robert K (2012. ) Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.Infection and immunity, , 80 (3 ) ,943-51 More Information

Rowe, Jared H; Ertelt, James M; Xin, Lijun; Way, Sing Sing (2012. ) Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance.PLoS pathogens, , 8 (8 ) ,e1002873 More Information

Ertelt, James M; Johanns, Tanner M; Mysz, Margaret A; Nanton, Minelva R; Rowe, Jared H; Aguilera, Marijo N; Way, Sing Sing (2011. ) Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection.Immunology, , 134 (4 ) ,487-97 More Information

Ertelt, James M; Rowe, Jared H; Mysz, Margaret A; Singh, Charanjeet; Roychowdhury, Monika; Aguilera, Marijo N; Way, Sing Sing (2011. ) Foxp3+ regulatory T cells impede the priming of protective CD8+ T cells.Journal of immunology (Baltimore, Md. : 1950), , 187 (5 ) ,2569-77 More Information

Rudd, Brian D; Venturi, Vanessa; Li, Gang; Samadder, Partha; Ertelt, James M; Way, Sing Sing; Davenport, Miles P; Nikolich-Žugich, Janko (2011. ) Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.Proceedings of the National Academy of Sciences of the United States of America, , 108 (33 ) ,13694-9 More Information

Rowe, Jared H; Ertelt, James M; Aguilera, Marijo N; Farrar, Michael A; Way, Sing Sing (2011. ) Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens.Cell host & microbe, , 10 (1 ) ,54-64 More Information

Johanns, Tanner M; Law, Calvin Y; Kalekar, Lokeshchandra A; O'Donnell, Hope; Ertelt, James M; Rowe, Jared H; Way, Sing Sing (2011. ) Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection.Microbes and infection / Institut Pasteur, , 13 (4 ) ,322-30 More Information

Han, Jin-Young; Hanson, David C; Way, Sing Sing (2011. ) Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child.The Pediatric infectious disease journal, , 30 (3 ) ,266-8 More Information

Ertelt, James M; Johanns, Tanner M; Rowe, Jared H; Way, Sing Sing (2010. ) Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production.Immunology, , 131 (2 ) ,183-91 More Information

Curtis, Meredith M; Rowell, Emily; Shafiani, Shahin; Negash, Amina; Urdahl, Kevin B; Wilson, Christopher B; Way, Sing Sing (2010. ) Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle.Cell host & microbe, , 8 (2 ) ,163-73 More Information

Johanns, Tanner M; Ertelt, James M; Rowe, Jared H; Way, Sing Sing (2010. ) Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection.PLoS pathogens, , 6 (8 ) ,e1001043 More Information

Winstead, Colleen J; Reilly, Cavan S; Moon, James J; Jenkins, Marc K; Hamilton, Sara E; Jameson, Stephen C; Way, Sing Sing; Khoruts, Alexander (2010. ) CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia.Journal of immunology (Baltimore, Md. : 1950), , 184 (9 ) ,4749-60 More Information

Rudd, Brian D; Venturi, Vanessa; Smithey, Megan J; Way, Sing Sing; Davenport, Miles P; Nikolich-Zugich, Janko (2010. ) Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.Journal of immunology (Baltimore, Md. : 1950), , 184 (6 ) ,2958-65 More Information

Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Rowe, Jared H; Avant, Ross A; Way, Sing Sing (2010. ) Naturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency.Journal of immunology (Baltimore, Md. : 1950), , 184 (2 ) ,869-76 More Information

Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Lai, Joseph C; Way, Sing Sing (2009. ) Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge.Immunology, , 128 (1 Suppl ) ,e471-8 More Information

Curtis, Meredith M; Way, Sing Sing; Wilson, Christopher B (2009. ) IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.Journal of immunology (Baltimore, Md. : 1950), , 183 (1 ) ,381-7 More Information

Ertelt, James M; Rowe, Jared H; Johanns, Tanner M; Lai, Joseph C; McLachlan, James B; Way, Sing Sing (2009. ) Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection.Journal of immunology (Baltimore, Md. : 1950), , 182 (5 ) ,3032-8 More Information

Curtis, Meredith M; Way, Sing Sing (2009. ) Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens.Immunology, , 126 (2 ) ,177-85 More Information

Rowe, Jared H; Johanns, Tanner M; Ertelt, James M; Way, Sing Sing (2008. ) PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes. Journal of immunology (Baltimore, Md. : 1950), , 180 (11 ) ,7553-7

Orgun, Nural N; Mathis, Meredith A; Wilson, Christopher B; Way, Sing Sing (2008. ) Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. Journal of immunology (Baltimore, Md. : 1950), , 180 (6 ) ,4109-15

Orgun, Nural N; Way, Sing Sing (2008. ) A critical role for phospholipase C in protective immunity conferred by listeriolysin O-deficient Listeria monocytogenes.Microbial pathogenesis, , 44 (2 ) ,159-63 More Information

Muller, William J; Orgun, Nural N; Dong, Lichun; Koelle, David M; Huang, Meei-Li; Way, Sing Sing (2008. ) Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2.Archives of virology, , 153 (6 ) ,1165-9 More Information

Asplin, Iain R; Carl, David J; Way, Sing Sing; Jones, Amanda L (2008. ) Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus.Microbial pathogenesis, , 44 (1 ) ,43-51 More Information

Orr, Mark T; Orgun, Nural N; Wilson, Christopher B; Way, Sing Sing (2007. ) Cutting edge: recombinant Listeria monocytogenes expressing a single immune-dominant peptide confers protective immunity to herpes simplex virus-1 infection. Journal of immunology (Baltimore, Md. : 1950), , 178 (8 ) ,4731-5

Way, Sing Sing; Havenar-Daughton, Colin; Kolumam, Ganesh A; Orgun, Nural N; Murali-Krishna, Kaja (2007. ) IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection. Journal of immunology (Baltimore, Md. : 1950), , 178 (7 ) ,4498-505

Kollmann, Tobias R; Reikie, Brian; Blimkie, Darren; Way, Sing Sing; Hajjar, Adeline M; Arispe, Kiea; Shaulov, Angela; Wilson, Christopher B (2007. ) Induction of protective immunity to Listeria monocytogenes in neonates. Journal of immunology (Baltimore, Md. : 1950), , 178 (6 ) ,3695-701

Way, Sing Sing; Wilson, Christopher B (2005. ) The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo.Infection and immunity, , 73 (9 ) ,6151-3 More Information

Way, Sing Sing; Wilson, Christopher B (2004. ) Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. Journal of immunology (Baltimore, Md. : 1950), , 173 (10 ) ,5918-22

Darveau, Richard P; Pham, Thu-Thao T; Lemley, Kayde; Reife, Robert A; Bainbridge, Brian W; Coats, Stephen R; Howald, William N; Way, Sing Sing; Hajjar, Adeline M (2004. ) Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4.Infection and immunity, , 72 (9 ) ,5041-51 More Information

Kollmann, Tobias R; Way, Sing Sing; Harowicz, Heidi L; Hajjar, Adeline M; Wilson, Christopher B (2004. ) Deficient MHC class I cross-presentation of soluble antigen by murine neonatal dendritic cells.Blood, , 103 (11 ) ,4240-2 More Information

Way, Sing Sing; Thompson, Lucas J; Lopes, Jared E; Hajjar, Adeline M; Kollmann, Tobias R; Freitag, Nancy E; Wilson, Christopher B (2004. ) Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cellular microbiology, , 6 (3 ) ,235-42

Way, Sing Sing; Kollmann, Tobias R; Hajjar, Adeline M; Wilson, Christopher B (2003. ) Cutting edge: protective cell-mediated immunity to Listeria monocytogenes in the absence of myeloid differentiation factor 88. Journal of immunology (Baltimore, Md. : 1950), , 171 (2 ) ,533-7

Shetron-Rama, Lynne M; Mueller, Kimberly; Bravo, Juan M; Bouwer, H G Archie; Way, Sing Sing; Freitag, Nancy E (2003. ) Isolation of Listeria monocytogenes mutants with high-level in vitro expression of host cytosol-induced gene products. Molecular microbiology, , 48 (6 ) ,1537-51

Almanan, Maha; Raynor, Jana; Ogunsulire, Ireti; Malyshkina, Anna; Mukherjee, Shibabrata; Hummel, Sarah A; Ingram, Jennifer T; Saini, Ankur; Xie, Markus M; Alenghat, Theresa; Way, Sing Sing; Deepe, George S; Divanovic, Senad; Singh, Harinder; Miraldi, Emily; Zajac, Allan J; Dent, Alexander L; Hölscher, Christoph; Chougnet, Claire; Hildeman, David A (2020. ) IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression.Science advances, , 6 (31 ) ,eabb0806 More Information

Burg, Ashley R; Erickson, John J; Turner, Lucien H; Pham, Giang; Kinder, Jeremy M; Way, Sing Sing (2020. ) Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes.Journal of immunology (Baltimore, Md. : 1950), , 205 (2 ) ,447-453 More Information

Kinder, Jeremy M; Turner, Lucien H; Stelzer, Ina A; Miller-Handley, Hilary; Burg, Ashley; Shao, Tzu-Yu; Pham, Giang; Way, Sing Sing (2020. ) CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization.Cell reports, , 31 (12 ) ,107784 More Information

Yang, Li; Shivakumar, Pranavkumar; Kinder, Jeremy; Way, Sing Sing; Donnelly, Bryan; Mourya, Reena; Luo, Zhenhua; Bezerra, Jorge A (2020. ) Regulation of bile duct epithelial injury by hepatic CD71+ erythroid cells.JCI insight, , 5 (11 ) , More Information

Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton (2020. ) Mouse models of neutropenia reveal progenitor-stage-specific defects.Nature, , 582 (7810 ) ,109-114 More Information

Kollmann, Tobias R; Marchant, Arnaud; Way, Sing Sing (2020. ) Vaccination strategies to enhance immunity in neonates.Science (New York, N.Y.), , 368 (6491 ) ,612-615 More Information

Chen, Yee-Shiuan; Chen, Iuan-Bor; Pham, Giang; Shao, Tzu-Yu; Bangar, Hansraj; Way, Sing Sing; Haslam, David B (2020. ) IL-17-producing ?? T cells protect against Clostridium difficile infection.The Journal of clinical investigation, , 130 (5 ) ,2377-2390 More Information

Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L (2019. ) Fungus Among Us: The Frenemies Within.Trends in immunology, , 40 (6 ) ,469-471 More Information

Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K (2019. ) TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.Journal of immunology (Baltimore, Md. : 1950), , 202 (9 ) ,2535-2545 More Information

Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing (2019. ) Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses.Cell host & microbe, , 25 (3 ) ,404-417.e6 More Information

Deshmukh, Hitesh; Way, Sing Sing (2019. ) Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications.Annual review of pathology, , 14 ,185-210 More Information

DiToro, Daniel; Winstead, Colleen J; Pham, Duy; Witte, Steven; Andargachew, Rakieb; Singer, Jeffrey R; Wilson, C Garrett; Zindl, Carlene L; Luther, Rita J; Silberger, Daniel J; Weaver, Benjamin T; Kolawole, E Motunrayo; Martinez, Ryan J; Turner, Henrietta; Hatton, Robin D; Moon, James J; Way, Sing Sing; Evavold, Brian D; Weaver, Casey T (2018. ) Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.Science (New York, N.Y.), , 361 (6407 ) , More Information

Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing (2018. ) Declining responsiveness to influenza vaccination with progression of human pregnancy.Vaccine, , 36 (31 ) ,4734-4741 More Information

Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-Žugich, Janko; Kuhns, Michael S (2018. ) A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.PloS one, , 13 (6 ) ,e0198354 More Information

Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M (2018. ) Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages.PLoS pathogens, , 14 (5 ) ,e1007060 More Information

Zhou, Jordan Z; Way, Sing Sing; Chen, Kang (2018. ) Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018).Trends in immunology, , 39 (4 ) ,355 More Information

Zhou, Jordan Z; Way, Sing Sing; Chen, Kang (2018. ) Immunology of the Uterine and Vaginal Mucosae.Trends in immunology, , 39 (4 ) ,302-314 More Information

Jiang, Tony T; Shao, Tzu-Yu; Ang, W X Gladys; Kinder, Jeremy M; Turner, Lucien H; Pham, Giang; Whitt, Jordan; Alenghat, Theresa; Way, Sing Sing (2017. ) Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria.Cell host & microbe, , 22 (6 ) ,809-816.e4 More Information

Lange, Shannon M; McKell, Melanie C; Schmidt, Stephanie M; Hossfeld, Austin P; Chaturvedi, Vandana; Kinder, Jeremy M; McAlees, Jaclyn W; Lewkowich, Ian P; Way, Sing Sing; Turner, Joanne; Qualls, Joseph E (2017. ) l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung.Frontiers in immunology, , 8 ,1561 More Information

Turner, Lucien H; Kinder, Jeremy M; Wilburn, Adrienne; D'Mello, Rahul J; Braunlin, Makayla R; Jiang, Tony T; Pham, Giang; Way, Sing Sing (2017. ) Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection.PLoS pathogens, , 13 (11 ) ,e1006684 More Information

Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing (2017. ) Reply: Breastfeeding-related maternal microchimerism.Nature reviews. Immunology, , 17 (11 ) ,730-1 More Information

Kinder, Jeremy M; Stelzer, Ina A; Arck, Petra C; Way, Sing Sing (2017. ) Immunological implications of pregnancy-induced microchimerism.Nature reviews. Immunology, , 17 (8 ) ,483-494 More Information

Navabi, Nazanin; Whitt, Jordan; Wu, Shu-En; Woo, Vivienne; Moncivaiz, Jessica; Jordan, Michael B; Vallance, Bruce A; Way, Sing Sing; Alenghat, Theresa (2017. ) Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation.Cell reports, , 19 (6 ) ,1165-1175 More Information

Cappelletti, Monica; Presicce, Pietro; Lawson, Matthew J; Chaturvedi, Vandana; Stankiewicz, Traci E; Vanoni, Simone; Harley, Isaac Tw; McAlees, Jaclyn W; Giles, Daniel A; Moreno-Fernandez, Maria E; Rueda, Cesar M; Senthamaraikannan, Paranth; Sun, Xiaofei; Karns, Rebekah; Hoebe, Kasper; Janssen, Edith M; Karp, Christopher L; Hildeman, David A; Hogan, Simon P; Kallapur, Suhas G; Chougnet, Claire A; Way, Sing Sing; Divanovic, Senad (2017. ) Type I interferons regulate susceptibility to inflammation-induced preterm birth.JCI insight, , 2 (5 ) ,e91288 More Information

Jiang, Tony T; Martinov, Tijana; Xin, Lijun; Kinder, Jeremy M; Spanier, Justin A; Fife, Brian T; Way, Sing Sing (2016. ) Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity.Cell reports, , 17 (7 ) ,1783-1794 More Information

Johnson, Lexus R; Weizman, Orr-El; Rapp, Moritz; Way, Sing Sing; Sun, Joseph C (2016. ) Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge.Cell reports, , 17 (3 ) ,636-644 More Information

Kinder, Jeremy M; Jiang, Tony T; Way, Sing Sing (2016. ) Offspring's Tolerance of Mother Goes Viral.Immunity, , 44 (5 ) ,1085-7 More Information

Rosenblum, Michael D; Way, Sing Sing; Abbas, Abul K (2016. ) Regulatory T cell memory.Nature reviews. Immunology, , 16 (2 ) ,90-101 More Information

Carpenter, Stephen M; Nunes-Alves, Cláudio; Booty, Matthew G; Way, Sing Sing; Behar, Samuel M (2016. ) A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis.PLoS pathogens, , 12 (1 ) ,e1005380 More Information

Legoux, Francois P; Lim, Jong-Baeck; Cauley, Andrew W; Dikiy, Stanislav; Ertelt, James; Mariani, Thomas J; Sparwasser, Tim; Way, Sing Sing; Moon, James J (2015. ) CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.Immunity, , 43 (5 ) ,896-908 More Information

Kinder, Jeremy M; Jiang, Tony T; Ertelt, James M; Xin, Lijun; Strong, Beverly S; Shaaban, Aimen F; Way, Sing Sing (2015. ) Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'.Chimerism, , 6 (1-2 ) ,8-20 More Information

Contact Information

Academic - CCHMC S Building
240 Albert Sabin Way
Cincinnati  Ohio, 45229
Phone: 513-636-7603
singsing.way@cchmc.org