Kathryn A. Wikenheiser-Brokamp, MD, PhD

Medical Degree: University of Cincinnati College of Medicine Cincinnati, OH, 1996

Doctorate: Cincinnati Children's Hospital Medical Center/University of Cincinnati College of Medicine Cincinnati, OH, 1994 (Developmental Biology)

Residency: Washington University-Barnes/Jewish Hospital St. Louis, MO, 2002 (Anatomic Pathology )

Clinical Trainee: Washington University St. Louis, MO , 2002

Pulmonary pathology, lung development, lung cancer

- Associate Professor, Cincinnati Children's Hospital Medical Center,

Investigators:Wikenheiser-Brokamp, Kathryn 01-01-2004 -12-31-2004 American Cancer Society - Ohio Chapter Retinoblastoma Gene Product (Rb) in Lung Carcinogenesis Role:PI Closed 003380-001 Level:Private Non-Profit

Grant: #R01-HL-079193 Investigators:Wikenheiser-Brokamp, Kathryn 04-01-2005 -01-31-2009 National Heart, Lung and Blood Institute Role of the Rb Family in Lung Epithelial Response to Injury Role:PI Closed 003422-001 Level:Federal

Investigators:Wikenheiser-Brokamp, Kathryn 01-01-2005 -12-31-2008 American Cancer Society - National Chapter Role of Retinoblastoma Protein Family in Lung Carcinogenesis Role:PI Active 003443-001 Level:Private Non-Profit

Peer Reviewed Publications

Privette Vinnedge, L M; McClaine, R; Wagh, P K; Wikenheiser-Brokamp, K A; Waltz, S E; Wells, S I  (2011). The human DEK oncogene stimulates ?-catenin signaling, invasion and mammosphere formation in breast cancer. OncogeneMore Information

Hagaman, Jared T; Panos, Ralph J; McCormack, Francis X; Thakar, Charuhas V; Wikenheiser-Brokamp, Kathryn A; Shipley, Ralph T; Kinder, Brent W  (2011). Vitamin D deficiency and reduced lung function in connective tissue-associated interstitial lung diseases. Chest, 139 (2) , 353-60More Information

Fuller, Kevin K; Richie, Daryl L; Feng, Xizhi; Krishnan, Karthik; Stephens, Timothy J; Wikenheiser-Brokamp, Kathryn A; Askew, David S; Rhodes, Judith C  (2011). Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus. Molecular microbiology, 79 (4) , 1045-62More Information

Simpson, David S; Mason-Richie, Nicole A; Gettler, Caitlin A; Wikenheiser-Brokamp, Kathryn A  (2009). Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis. Cancer research, 69 (22) , 8733-41More Information

Hill, D Ashley; Ivanovich, Jennifer; Priest, John R; Gurnett, Christina A; Dehner, Louis P; Desruisseau, David; Jarzembowski, Jason A; Wikenheiser-Brokamp, Kathryn A; Suarez, Brian K; Whelan, Alison J; Williams, Gretchen; Bracamontes, Dawn; Messinger, Yoav; Goodfellow, Paul J  (2009). DICER1 mutations in familial pleuropulmonary blastoma. Science (New York, N.Y.), 325 (5943) , 965More Information

Wise-Draper, Trisha M; Morreale, Richard J; Morris, Teresa A; Mintz-Cole, Rachael A; Hoskins, Elizabeth E; Balsitis, Scott J; Husseinzadeh, Nader; Witte, David P; Wikenheiser-Brokamp, Kathryn A; Lambert, Paul F; Wells, Susanne I  (2009). DEK proto-oncogene expression interferes with the normal epithelial differentiation program. The American journal of pathology, 174 (1) , 71-81More Information

Young, L.R., Franz, D.N., Nagarkatte, P., Fletcher, C.D.M., Wikenheiser-Brokamp, K.A., Galsky, M.D., Lam, A., Gelfand, M.J., McCormack, F.X.  (2009). Utility of FDG-PET in lymphangioleiomyomatosis and tuberous sclerosis complex. Chest, 136 (3) , 962-933

Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Fischer, Aryeh; McCormack, Francis X  (2016). Diffuse Cystic Lung Disease as the Presenting Manifestation of Sjögren Syndrome. Annals of the American Thoracic Society, 13 (3) , 371-5More Information

Chlon, Timothy M; Ruiz-Torres, Sonya; Maag, Logan; Mayhew, Christopher N; Wikenheiser-Brokamp, Kathryn A; Davies, Stella M; Mehta, Parinda; Myers, Kasiani C; Wells, James M; Wells, Susanne I  (2016). Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem cell reports, 6 (1) , 44-54More Information

Saito, Atsushi; Nikolaidis, Nikolaos M; Amlal, Hassane; Uehara, Yasuaki; Gardner, Jason C; LaSance, Kathleen; Pitstick, Lori B; Bridges, James P; Wikenheiser-Brokamp, Kathryn A; McGraw, Dennis W; Woods, Jason C; Sabbagh, Yves; Schiavi, Susan C; Altini?ik, Göksel; Jakopovi?, Marko; Inoue, Yoshikazu; McCormack, Francis X  (2015). Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment. Science translational medicine, 7 (313) , 313ra181More Information

Klein, Melissa; Hershey, Gurjit K Khurana; Devarajan, Prasad; Muglia, Louis J; Wikenheiser-Brokamp, Kathryn A; Loch, Jill; Hostetter, Margaret K; Strauss, Arnold W; DeWitt, Thomas G  (2015). Enhancing Pediatric Fellows' Research Training: Development of an Office of Pediatric Clinical Fellowships. The Journal of pediatrics, 167 (3) , 506-7.e1More Information

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X  (2015). Diffuse Cystic Lung Disease. Part II. American journal of respiratory and critical care medicine, 192 (1) , 17-29More Information

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X  (2015). Diffuse Cystic Lung Disease. Part I. American journal of respiratory and critical care medicine, 191 (12) , 1354-66More Information

Wagh, Purnima K; Gardner, Margaret A; Ma, Xiaolan; Callahan, Melissa; Shannon, John M; Wert, Susan E; Messinger, Yoav H; Dehner, Louis P; Hill, D Ashley; Wikenheiser-Brokamp, Kathryn A  (2015). Cell- and developmental stage-specific Dicer1 ablation in the lung epithelium models cystic pleuropulmonary blastoma. The Journal of pathology, 236 (1) , 41-52More Information

Lombardi, Anne J; Hoskins, Elizabeth E; Foglesong, Grant D; Wikenheiser-Brokamp, Kathryn A; Wiesmüller, Lisa; Hanenberg, Helmut; Andreassen, Paul R; Jacobs, Allison J; Olson, Susan B; Keeble, Winifred W; Hays, Laura E; Wells, Susanne I  (2015). Acquisition of Relative Interstrand Crosslinker Resistance and PARP Inhibitor Sensitivity in Fanconi Anemia Head and Neck Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research, 21 (8) , 1962-72More Information

Adams, A K; Hallenbeck, G E; Casper, K A; Patil, Y J; Wilson, K M; Kimple, R J; Lambert, P F; Witte, D P; Xiao, W; Gillison, M L; Wikenheiser-Brokamp, K A; Wise-Draper, T M; Wells, S I  (2015). DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. Oncogene, 34 (7) , 868-77More Information

Akeno, N; Miller, A L; Ma, X; Wikenheiser-Brokamp, K A  (2015). p53 suppresses carcinoma progression by inhibiting mTOR pathway activation. Oncogene, 34 (5) , 589-99More Information

McCauley, Heather A; Liu, Chia-Yang; Attia, Aria C; Wikenheiser-Brokamp, Kathryn A; Zhang, Yujin; Whitsett, Jeffrey A; Guasch, Géraldine  (2014). TGF? signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. Development (Cambridge, England), 141 (23) , 4628-39More Information

Chlon, Timothy M; Hoskins, Elizabeth E; Mayhew, Christopher N; Wikenheiser-Brokamp, Kathryn A; Davies, Stella M; Mehta, Parinda; Myers, Kasiani C; Wells, James M; Wells, Susanne I  (2014). High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells. Journal of virology, 88 (19) , 11315-26More Information

Zafar, Muhammad A; McCormack, Francis X; Rahman, Shahid; Tencza, Christian; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Shizukuda, Yukitaka; Elwing, Jean M  (2013). Pulmonary vascular shunts in exercise-intolerant patients with lymphangioleiomyomatosis. American journal of respiratory and critical care medicine, 188 (9) , 1167-70More Information

Alsidawi, S; Morris, J C; Wikenheiser-Brokamp, K A; Starnes, S L; Karim, N A  (2013). Mucoepidermoid carcinoma of the lung: a case report and literature review. Case reports in oncological medicine, 2013, 625243More Information

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Byrnes, Sue; McCormack, Francis X  (2012). Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis. Frontiers of medicine, 6 (4) , 395-405More Information

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; McCormack, Francis X  (2012). Lymphangioleiomyomatosis: new concepts in pathogenesis, diagnosis, and treatment. Seminars in respiratory and critical care medicine, 33 (5) , 486-97More Information

Wise-Draper, Trisha M; Draper, David J; Gutkind, J Silvio; Molinolo, Alfredo A; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I  (2012). Future directions and treatment strategies for head and neck squamous cell carcinomas. Translational research : the journal of laboratory and clinical medicine, 160 (3) , 167-77More Information

Hoskins, Elizabeth E; Morreale, Richard J; Werner, Stephen P; Higginbotham, Jennifer M; Laimins, Laimonis A; Lambert, Paul F; Brown, Darron R; Gillison, Maura L; Nuovo, Gerard J; Witte, David P; Kim, Mi-Ok; Davies, Stella M; Mehta, Parinda A; Butsch Kovacic, Melinda; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I  (2012). The fanconi anemia pathway limits human papillomavirus replication. Journal of virology, 86 (15) , 8131-8More Information

Gupta, Nishant; Aragaki, Alejandro; Wikenheiser-Brokamp, Kathryn A; Benzaquen, Sadia; Panos, Ralph J  (2012). Occam's razor or Hickam's dictum?. Journal of bronchology & interventional pulmonology, 19 (3) , 216-9More Information

Privette Vinnedge, Lisa M; Ho, Shuk-Mei; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I  (2012). The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer. PloS one, 7 (10) , e46985More Information

Sen, M; Akeno, N; Reece, A; Miller, A L; Simpson, D S; Wikenheiser-Brokamp, K A  (2017). p16 controls epithelial cell growth and suppresses carcinogenesis through mechanisms that do not require RB1 function. Oncogenesis, 6 (4) , e320More Information

Sriprasart, Thitiwat; Aragaki, Alejandro; Baughman, Robert; Wikenheiser-Brokamp, Kathryn; Khanna, Gaurav; Tanase, Daniel; Kirschner, Michelle; Benzaquen, Sadia  (2017). A Single US Center Experience of Transbronchial Lung Cryobiopsy for Diagnosing Interstitial Lung Disease With a 2-Scope Technique. Journal of bronchology & interventional pulmonology, 24 (2) , 131-135More Information

Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut  (2017). Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells. Cell reports, 18 (11) , 2608-2621More Information

Wikenheiser-Brokamp, Kathryn A; Klein, Melissa; Hershey, Gurjit K Khurana; Devarajan, Prasad; DeWitt, Thomas G; Loch, Jill; Strauss, Arnold W; Muglia, Louis J; Hostetter, Margaret K  (2017). Evaluation of Fellows' CrossTalk Effectiveness in Promoting Transdisciplinary Networking and Research. The Journal of pediatrics, 181, 5-6.e3More Information

Xu, Yan; Mizuno, Takako; Sridharan, Anusha; Du, Yina; Guo, Minzhe; Tang, Jie; Wikenheiser-Brokamp, Kathryn A; Perl, Anne-Karina T; Funari, Vincent A; Gokey, Jason J; Stripp, Barry R; Whitsett, Jeffrey A  (2016). Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. JCI insight, 1 (20) , e90558More Information

Osterburg, Andrew R; Nelson, Rebecca L; Yaniv, Benyamin Z; Foot, Rachel; Donica, Walter R F; Nashu, Madison A; Liu, Huan; Wikenheiser-Brokamp, Kathryn A; Moss, Joel; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T  (2016). NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline. JCI insight, 1 (16) , e87270More Information

McCormack, Francis X; Gupta, Nishant; Finlay, Geraldine R; Young, Lisa R; Taveira-DaSilva, Angelo M; Glasgow, Connie G; Steagall, Wendy K; Johnson, Simon R; Sahn, Steven A; Ryu, Jay H; Strange, Charlie; Seyama, Kuniaki; Sullivan, Eugene J; Kotloff, Robert M; Downey, Gregory P; Chapman, Jeffrey T; Han, MeiLan K; D'Armiento, Jeanine M; Inoue, Yoshikazu; Henske, Elizabeth P; Bissler, John J; Colby, Thomas V; Kinder, Brent W; Wikenheiser-Brokamp, Kathryn A; Brown, Kevin K; Cordier, Jean F; Meyer, Cristopher; Cottin, Vincent; Brozek, Jan L; Smith, Karen; Wilson, Kevin C; Moss, Joel  (2016). Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management. American journal of respiratory and critical care medicine, 194 (6) , 748-61More Information

Dehner, Louis P; Messinger, Yoav H; Schultz, Kris Ann P; Williams, Gretchen M; Wikenheiser-Brokamp, Kathryn; Hill, D AshleyPleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 18 (6) , 504-11More Information

Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan  (2014). Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 (3) , 978-84More Information

Cundiff, William B; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Kotloff, Robert; Benzaquen, Sadia  (2014). Successful management of a chronic, refractory bronchopleural fistula with endobronchial valves followed by talc pleurodesis. American journal of respiratory and critical care medicine, 189 (4) , 490-1More Information

McCormack, Francis X; Wilmott, Clay; Young, Lisa R; Wikenheiser-Brokamp, Kathryn  (2013). An atoll variant that mocks. American journal of respiratory and critical care medicine, 188 (1) , 110More Information

Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan  (2011). Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11, 513More Information

Mayhew, Christopher N; Carter, Scott L; Fox, Sejal R; Sexton, Charlene R; Reed, Christopher A; Srinivasan, Seetha V; Liu, Xiangdong; Wikenheiser-Brokamp, Kathryn; Boivin, Gregory P; Lee, Ju-Seog; Aronow, Bruce J; Thorgeirsson, Snorri S; Knudsen, Erik S  (2007). RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis. Gastroenterology, 133 (3) , 976-84More Information

Ciampi, Raffaele; Giordano, Thomas J; Wikenheiser-Brokamp, Kathryn; Koenig, Ronald J; Nikiforov, Yuri E  (2007). HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma. Endocrine-related cancer, 14 (2) , 445-52More Information

Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kouhei; Li, Na; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Borchers, Michael T; Kopras, Elizabeth J; Plas, David R; Sun, Julia; Franz, David N; Capal, Jamie K; Mays, Maxwell; Sun, Yang; Kwiatkowski, David J; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J  (2017). Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells. Molecular cancer research : MCR, 15 (10) , 1318-1330More Information

Akeno, Nagako; Reece, Alisa L; Callahan, Melissa; Miller, Ashley L; Kim, Rebecca G; He, Diana; Lane, Adam; Moulton, Jonathan S; Wikenheiser-Brokamp, Kathryn A  (2017). Trp53 Mutants Drive Neuroendocrine Lung Cancer through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response. Molecular cancer therapeuticsMore Information

Gao, Denny K; Salomonis, Nathan; Henderlight, Maggie; Woods, Christopher; Thakkar, Kairavee; Grom, Alexei A; Thornton, Sherry; Jordan, Michael B; Wikenheiser-Brokamp, Kathryn A; Schulert, Grant S  (2021). IFN-? is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome. JCI insight, 6 (17) More Information

Pearson, Joel D; Huang, Katherine; Pacal, Marek; McCurdy, Sean R; Lu, Suying; Aubry, Arthur; Yu, Tao; Wadosky, Kristine M; Zhang, Letian; Wang, Tao; Gregorieff, Alex; Ahmad, Mohammad; Dimaras, Helen; Langille, Ellen; Cole, Susan P C; Monnier, Philippe P; Lok, Benjamin H; Tsao, Ming-Sound; Akeno, Nagako; Schramek, Daniel; Wikenheiser-Brokamp, Kathryn A; Knudsen, Erik S; Witkiewicz, Agnieszka K; Wrana, Jeffrey L; Goodrich, David W; Bremner, Rod  (2021). Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity. Cancer cell, 39 (8) , 1115-1134.e12More Information

Ruiz-Torres, Sonya; Lambert, Paul F; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I  (2021). Directed differentiation of human pluripotent stem cells into epidermal stem and progenitor cells. Molecular biology reports, 48 (8) , 6213-6222More Information

Hawkins, Padraig; Chawke, Liam; Cormican, Liam; Wikenheiser-Brokamp, Kathryn A; Fabre, Aurelie; Keane, Michael P; McCarthy, Cormac  (2021). Autoimmune pulmonary alveolar proteinosis: a discrepancy between symptoms and CT findings. Lancet (London, England), 398 (10296) , e7More Information

Ogden, Herbert Luke; Kim, Hoyeol; Wikenheiser-Brokamp, Kathryn A; Naren, Anjaparavanda P; Mun, Kyu Shik  (2021). Cystic Fibrosis Human Organs-on-a-Chip. Micromachines, 12 (7) More Information

Hayes, Don; Darland, Leanna K; Hjelm, Michelle A; Mansour, Heidi M; Wikenheiser-Brokamp, Kathryn A  (2021). To treat or not to treat: CFTR modulators after lung transplantation. Pediatric transplantation, 25 (4) , e14007More Information

Bedard, Mary C; de Alarcon, Alessandro; Kou, Yann-Fuu; Lee, David; Sestito, Alexandra; Duggins, Angela L; Brusadelli, Marion; Lane, Adam; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I; Smith, David F  (2021). HPV Strain Predicts Severity of Juvenile-Onset Recurrent Respiratory Papillomatosis with Implications for Disease Screening. Cancers, 13 (11) More Information

Benzaquen, Sadia; Kaini, Navin; Gupta, Ena; Litwin, Dianne; Wikenheiser-Brokamp, Kathryn A; Aragaki-Nakahodo, Alejandro  (2021). Women Presenting With Asthma and Persistent Wheezing: A Case Series. Chest, 159 (4) , e267-e275More Information

Ruiz-Torres, Sonya; Brusadelli, Marion G; Witte, David P; Wikenheiser-Brokamp, Kathryn A; Sauter, Sharon; Nelson, Adam S; Sertorio, Mathieu; Chlon, Timothy M; Lane, Adam; Mehta, Parinda A; Myers, Kasiani C; Bedard, Mary C; Pal, Bidisha; Supp, Dorothy M; Lambert, Paul F; Komurov, Kakajan; Kovacic, Melinda Butsch; Davies, Stella M; Wells, Susanne I  (2021). Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin. Cell stem cell, 28 (3) , 424-435.e6More Information

Bedard, Mary C; Brusadelli, Marion G; Carlile, Adrean; Ruiz-Torres, Sonya; Lodin, Hannah; Lee, Denis; Kofron, Matthew; Lambert, Paul F; Lane, Adam; Ameziane, Najim; Bahassi, El Mustapha; Wikenheiser-Brokamp, Kathryn A; de Alarcon, Alessandro; Smith, David F; Wells, Susanne I  (2021). Patient-Derived Organotypic Epithelial Rafts Model Phenotypes in Juvenile-Onset Recurrent Respiratory Papillomatosis. Viruses, 13 (1) More Information

Kosciuk, Patrick; Meyer, Cristopher; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X  (2020). Pulmonary alveolar microlithiasis. European respiratory review : an official journal of the European Respiratory Society, 29 (158) More Information

Guo, Minzhe; Yu, Jane J; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn A; Riccetti, Matt; Zhang, Erik Y; Sudha, Parvathi; Adam, Mike; Potter, Andrew; Kopras, Elizabeth J; Giannikou, Krinio; Potter, S Steven; Sherman, Sue; Hammes, Stephen R; Kwiatkowski, David J; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan  (2020). Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American journal of respiratory and critical care medicine, 202 (10) , 1373-1387More Information

Stevens, Mariana L; Zhang, Zhonghua; Johansson, Elisabet; Ray, Samriddha; Jagpal, Amrita; Ruff, Brandy P; Kothari, Arjun; He, Hua; Martin, Lisa J; Ji, Hong; Wikenheiser-Brokamp, Kathryn; Weirauch, Matthew T; Supp, Dorothy M; Biagini Myers, Jocelyn M; Khurana Hershey, Gurjit K  (2020). Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk. Nature communications, 11 (1) , 4092More Information

Oltvai, Zoltán N; Smith, Eric A; Wiens, Katie; Nogee, Lawrence M; Luquette, Mark; Nelson, Andrew C; Wikenheiser-Brokamp, Kathryn A  (2020). Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter. Cold Spring Harbor molecular case studies, 6 (3) More Information

Liu, Huan; Osterburg, Andrew R; Flury, Jennifer; Swank, Zulma; McGraw, Dennis W; Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Kumar, Ashish; Tazi, Abdellatif; Inoue, Yoshikazu; Hirose, Masaki; McCormack, Francis X; Borchers, Michael T  (2020). MAPK mutations and cigarette smoke promote the pathogenesis of pulmonary Langerhans cell histiocytosis. JCI insight, 5 (4) More Information

Suzuki, Takuji; McCarthy, Cormac; Carey, Brenna C; Borchers, Michael; Beck, David; Wikenheiser-Brokamp, Kathryn A; Black, Dianna; Chalk, Claudia; Trapnell, Bruce C  (2020). Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis. American journal of respiratory cell and molecular biology, 62 (1) , 87-94More Information

Obaidat, Baha; Yazdani, Dina; Wikenheiser-Brokamp, Kathryn A; Gupta, Nishant  (2020). Diffuse Cystic Lung Diseases. Respiratory care, 65 (1) , 111-126More Information

Schulert, Grant S; Yasin, Shima; Carey, Brenna; Chalk, Claudia; Do, Thuy; Schapiro, Andrew H; Husami, Ammar; Watts, Allen; Brunner, Hermine I; Huggins, Jennifer; Mellins, Elizabeth D; Morgan, Esi M; Ting, Tracy; Trapnell, Bruce C; Wikenheiser-Brokamp, Kathryn A; Towe, Christopher; Grom, Alexei A  (2019). Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease: Characterization and Risk Factors. Arthritis & rheumatology (Hoboken, N.J.), 71 (11) , 1943-1954More Information

Wang, Yuhua; Pandey, Ram Naresh; York, Allen J; Mallela, Jaya; Nichols, William C; Hu, Yueh-Chiang; Molkentin, Jeffery D; Wikenheiser-Brokamp, Kathryn A; Hegde, Rashmi S  (2019). The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension. Nature communications, 10 (1) , 4143More Information

Taylor, Deanne M; Aronow, Bruce J; Tan, Kai; Bernt, Kathrin; Salomonis, Nathan; Greene, Casey S; Frolova, Alina; Henrickson, Sarah E; Wells, Andrew; Pei, Liming; Jaiswal, Jyoti K; Whitsett, Jeffrey; Hamilton, Kathryn E; MacParland, Sonya A; Kelsen, Judith; Heuckeroth, Robert O; Potter, S Steven; Vella, Laura A; Terry, Natalie A; Ghanem, Louis R; Kennedy, Benjamin C; Helbig, Ingo; Sullivan, Kathleen E; Castelo-Soccio, Leslie; Kreigstein, Arnold; Herse, Florian; Nawijn, Martijn C; Koppelman, Gerard H; Haendel, Melissa; Harris, Nomi L; Rokita, Jo Lynne; Zhang, Yuanchao; Regev, Aviv; Rozenblatt-Rosen, Orit; Rood, Jennifer E; Tickle, Timothy L; Vento-Tormo, Roser; Alimohamed, Saif; Lek, Monkol; Mar, Jessica C; Loomes, Kathleen M; Barrett, David M; Uapinyoying, Prech; Beggs, Alan H; Agrawal, Pankaj B; Chen, Yi-Wen; Muir, Amanda B; Garmire, Lana X; Snapper, Scott B; Nazarian, Javad; Seeholzer, Steven H; Fazelinia, Hossein; Singh, Larry N; Faryabi, Robert B; Raman, Pichai; Dawany, Noor; Xie, Hongbo Michael; Devkota, Batsal; Diskin, Sharon J; Anderson, Stewart A; Rappaport, Eric F; Peranteau, William; Wikenheiser-Brokamp, Kathryn A; Teichmann, Sarah; Wallace, Douglas; Peng, Tao; Ding, Yang-Yang; Kim, Man S; Xing, Yi; Kong, Sek Won; Bönnemann, Carsten G; Mandl, Kenneth D; White, Peter S  (2019). The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental cell, 49 (1) , 10-29More Information

Suhrie, Kristen; Pajor, Nathan M; Ahlfeld, Shawn K; Dawson, D Brian; Dufendach, Kevin R; Kitzmiller, Joseph A; Leino, Daniel; Lombardo, Rachel C; Smolarek, Teresa A; Rathbun, Pamela A; Whitsett, Jeffrey A; Towe, Christopher; Wikenheiser-Brokamp, Kathryn A  (2019). Neonatal Lung Disease Associated with TBX4 Mutations. The Journal of pediatrics, 206, 286-292.e1More Information

Zimmermann, Nives; Wikenheiser-Brokamp, Kathryn A  (2018). Hypereosinophilic syndrome in the differential diagnosis of pulmonary infiltrates with eosinophilia. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 121 (2) , 179-185More Information

Gupta, Nishant; Colby, Thomas V; Meyer, Cristopher A; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn A  (2018). Smoking-Related Diffuse Cystic Lung Disease. Chest, 154 (2) , e31-e35More Information

Wang, Yuhua; Pandey, Ram Naresh; Riffle, Stephen; Chintala, Hemabindu; Wikenheiser-Brokamp, Kathryn A; Hegde, Rashmi S  (2018). The Protein Tyrosine Phosphatase Activity of Eyes Absent Contributes to Tumor Angiogenesis and Tumor Growth. Molecular cancer therapeutics, 17 (8) , 1659-1669More Information

Matrka, Marie C; Cimperman, Katherine A; Haas, Sarah R; Guasch, Geraldine; Ehrman, Lisa A; Waclaw, Ronald R; Komurov, Kakajan; Lane, Adam; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I  (2018). Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. PLoS genetics, 14 (3) , e1007227More Information

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