Theresa Winhusen

Theresa M Winhusen

Professor of Psychiatry & Vice Chair of Addiction Sciences

Professional Summary

DR. THERESA WINHUSEN is the Donald C. Harrison Endowed Chair in Medicine, a Professor of Psychiatry and Behavioral Neuroscience, and the Vice Chair of Addiction Sciences. Dr. Winhusen has conducted NIDA-funded clinical trials for the past 20 years devoted to improving the treatment of substance use disorders including opioid, cocaine, and tobacco use disorders.

Education

Doctoral Degree, Indiana University 1996 (Clinical Psychology)

Bachelor's Degree, University of Cincinnati 1990 (Psychology)

Positions and Work Experience

2012 -To Present Associate Professor, Department of Psychiatry and Behavioral Neuroscience, College of Medicine University of Cincinnati Cincinnati, OH ,

2006 -2012 Research Associate Professor, Psychiatry and Behavioral Neuroscience Department, College of Medicine, University of Cincinnati, Cincinnati, OH

2001 -2006 Research Assistant Professor, Psychiatry Department, College of Medicine, University of Cincinnati, Cincinnati, OH

2001 -To Present Supervisor, Duties: psychological work supervision for master’s level employees, Cincinnati Addiction Research Center, Cincinnati, Ohio

2000 -To Present Associate Director, Cincinnati Addiction Research Center, Cincinnati, Ohio

1999 -To Present Licensed Psychologist, #5568, Ohio

1999 -2000 Psychologist (part-time), Trihealth Psychological Services, Cincinnati, Ohio

1997 -1999 Psychology Fellow (part-time), Trihealth Psychological Services, Cincinnati, Ohio

1996 -2001 Research Psychologist, NIDA’s Cincinnati Medication Development Research Unit, Cincinnati, Ohio

1995 -1996 Clinical Psychology Intern, VA Medical Center, Cincinnati, OH

1993 -1995 Clinical Associate Instructor, Duties: trained graduate students in psychological assessment and report writing, Indiana University, Bloomington, IN

1992 - Instructor, Duties: designed and taught a course on research methodology, Indiana University, Bloomington, IN

Research and Practice Interests

Dr. Winhusen is one of the foremost experts in conducting multi-site addiction clinical trials in community practice settings, having been the national PI for five multi-site clinical trials in NIDA’s Clinical Trials network (CTN) since 2001. Throughout the last 18 years, Dr. Winhusen has conducted NIDA-funded research to identify effective substance abuse treatments with a particular emphasis on treating tobacco and stimulant use disorders and has been awarded >12.4 million dollars in NIH funding.

As the ASD Director, Dr. Winhusen oversees ASD clinical services, which include medication assisted treatment for opioid use disorder (methadone and buprenorphine maintenance), co-occurring disorders treatment, perinatal addictions treatment, and general outpatient substance use disorders treatment.
 

UC Health Clinical Focus

Psychology

UC Health Specialities

Psychology

Research Support

Grant: #U10DA013733-CTN-0052 2011 -2015 NIDA A Randomized Controlled Trial of Buspirone for Relapse-Prevention in Adults with Cocaine Dependence Role:Principal Investigator

Grant: #U10DA013733-CTN-0046 2009 -2013 Smoking-cessation and stimulant treatment Role:Principal Investigator

Grant: #R01DA025249 2008 -2012 NIDA NIDA Coordinated R01, Multisite Controlled Trial of Cocaine Vaccine (2 of 6) Role:Co-Investigator

Grant: #R01 DA025249 Investigators:Somoza, Eugene; Winhusen, Theresa 09-01-2008 -01-31-2013 National Institute on Drug Abuse Controlled Trial of Cocaine Vaccine (2 of 6) Cincinnati Treatment Center Role:Collaborator $792,842.00 Active Level:Federal

Grant: #PRO-806-019 / 1 RC2 DA028910-01 Rev Investigators:Somoza, Eugene; Winhusen, Theresa 09-30-2009 -08-31-2011 National Institute on Drug Abuse A Six-Month, RCT of Probuphine Safety and Efficacy in the Treatment of Opioid Addiction Role:Collaborator $537,129.00 Active Level:Federal

Grant: #U10 DA013732 Investigators:Burlew, Ann Kathleen Hoard; Fichtenbaum, Carl; Horn, Paul; Lyons, Michael; Somoza, Eugene; Winhusen, Theresa; Wulsin, Lawson 09-15-2010 -08-31-2015 National Institute on Drug Abuse Competing Renewal of Clinical Trials Network, Ohio Valley Node Role:PI $10,370,010.00 Active Level:Federal

Grant: #Prime HHSN271201200020C Investigators:Somoza, Eugene; Winhusen, Theresa 08-15-2012 -02-14-2013 National Institute on Drug Abuse Phase I Patient Study for Subcontract under AiCT SBIR Medication Adherence in Higher Risk Populations Role:Collaborator $17,824.00 Active Level:Federal

Grant: #APNF Research Grant Investigators:Osterman, Robin; Winhusen, Theresa 06-01-2014 -05-31-2015 American Psychiatric Nursing Foundation Alcohol Use Biomarkers in Pregnant Methadone Users Role:Collaborator $5,000.00 Awarded Level:Private Non-Profit

Grant: #NIDA-VA AZD8529 Investigators:Winhusen, Theresa 05-01-2015 -10-31-2016 National Institute on Drug Abuse A Phase 2, Multi-Center Trial of AZD8529 for Smoking Cessaton In Female Smokers Role:PI $457,556.00 Awarded Level:Federal

Grant: #UG1DA013732 Investigators:Elder, Nancy; Lyons, Michael; Winhusen, Theresa 09-01-2015 -05-31-2020 National Institute on Drug Abuse Ohio Valley Node-Network (OVNN) of the NIDA Clinical Trials Network Role:PI $789,514.00 Awarded Level:Federal

Grant: #U10DA013732 Investigators:Winhusen 09-01-2015 -05-31-2020 NIDA NIDA Cooperative Agreement Role:PI 3952624 Active Type:Grant

Grant: #U10DA013732 Investigators:Winhusen 2015 -2020 NIDA Role:PI 3,952,624 Active Type:Grant

Grant: #AZD Investigators:Winhusem, Theresa 2015 -2016 NIH/NIDA Phase 2, Multi-Center Trial of AZD8529 for Smoking Cessation in Female Smokers Role:Principal Investigator 457,556 Active Type:Grant

Grant: #GRAND Award Investigators:Winhusen, Theresa 2015 -2016 Pfizer, Inc A Pilot Randomized, Placebo-Controlled, Crossover Study of the Effect of the Nicotine Nasal Spray and Varenicline on Cigarette Smoking following Methadone Dosing in Methadone-Maintained Patients Role:PI 150,000 Type:Grant

Grant: #R34DA040862 Investigators:Lyons, Michael; Welge, Jeffrey; Wilder, Christine; Winhusen, Theresa 09-15-2016 -06-30-2019 National Institute on Drug Abuse A tailored, peer-delivered intervention to reduce recurring opioid overdoses Role:PI $225,150.00 Active Level:Federal

Grant: #VA-CSPCC #1033 Investigators:Brown, Jennifer; Pandalai, Soumya; Winhusen, Theresa 06-01-2017 -02-28-2019 National Institute on Drug Abuse Phase 2, Multi-Center Trial of Lorcaserin for the Treatment of Cocaine Use Disorder Role:PI $728,149.00 Active Level:Federal

Grant: #R01DA044248 Investigators:Elder, Nancy; Regan, Saundra; Welge, Jeffrey; Winhusen, Theresa 09-01-2017 -06-30-2022 National Institute on Drug Abuse EMPOWER: Evaluating the ability to reduce Morphine equivalent dose for chronic Pain patients receiving Opioid-therapy through a Web-based E-Health self-management program: a Randomized multi-site Clin Role:PI $619,130.00 Active Level:Federal

Grant: #OSU (NIH NIDA) Investigators:Brown, Jennifer; Latessa, Edward; Lyons, Michael; McMullan, Jason; Winhusen, Theresa 04-17-2019 -03-31-2023 National Institute on Drug Abuse Optimizing HEALing in Ohio Communities (OHIO) Role:PI $2,958,861.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Brigham, Gregory S; Slesnick, Natasha; Winhusen, Theresa M; Lewis, Daniel F; Guo, Xiamei; Somoza, Eugene (2014. )A randomized pilot clinical trial to evaluate the efficacy of Community Reinforcement and Family Training for Treatment Retention (CRAFT-T) for improving outcomes for patients completing opioid detoxification.Drug and alcohol dependence, ,138 ,240-3

Campbell, Aimee N C; Nunes, Edward V; Matthews, Abigail G; Stitzer, Maxine; Miele, Gloria M; Polsky, Daniel; Turrigiano, Eva; Walters, Scott; McClure, Erin A; Kyle, Tiffany L; Wahle, Aimee; Van Veldhuisen, Paul; Goldman, Bruce; Babcock, Dean; Stabile, Patricia Quinn; Winhusen, Theresa; Ghitza, Udi E (2014. )Internet-Delivered Treatment for Substance Abuse: A Multisite Randomized Controlled Trial.The American journal of psychiatry, ,

Winhusen, Theresa M; Brigham, Gregory S; Kropp, Frankie; Lindblad, Robert; Gardin, John G; Penn, Pat; Hodgkins, Candace; Kelly, Thomas M; Douaihy, Antoine; McCann, Michael; Love, Lee D; Degravelles, Eliot; Bachrach, Ken; Sonne, Susan C; Hiott, Bob; Haynes, Louise; Sharma, Gaurav; Lewis, Daniel F; Vanveldhuisen, Paul; Theobald, Jeff; Ghitza, Udi (2014. )A randomized trial of concurrent smoking-cessation and substance use disorder treatment in stimulant-dependent smokers.The Journal of clinical psychiatry, ,75 (4 ),336-43

Denton, Wayne H; Adinoff, Bryon H; Lewis, Daniel; Walker, Robrina; Winhusen, Theresa (2014. )Family discord is associated with increased substance use for pregnant substance users.Substance use & misuse, ,49 (3 ),326-32

Winhusen, Theresa M; Kropp, Frankie; Theobald, Jeff; Lewis, Daniel F (2014. )Achieving smoking abstinence is associated with decreased cocaine use in cocaine-dependent patients receiving smoking-cessation treatment.Drug and alcohol dependence, ,134 ,391-5

Winhusen, Theresa M; Kropp, Frankie; Lindblad, Robert; Douaihy, Antoine; Haynes, Louise; Hodgkins, Candace; Chartier, Karen; Kampman, Kyle M; Sharma, Gaurav; Lewis, Daniel F; VanVeldhuisen, Paul; Theobald, Jeff; May, Jeanine; Brigham, Gregory S (2014. )Multisite, randomized, double-blind, placebo-controlled pilot clinical trial to evaluate the efficacy of buspirone as a relapse-prevention treatment for cocaine dependence.The Journal of clinical psychiatry, ,

Winstanley, Erin L; Brigham, Greg S; Babcock, Dean; Winhusen, Theresa (2014. )Improving Treatment for Opioid Dependence: A Perspective From the Ohio Valley Node of the NIDA Clinical Trials Network.Progress in community health partnerships : research, education, and action, ,8 (1 ),99-107

Winhusen T, Kropp F, Theobald J, Lewis DF (2013. )Achieving smoking abstinence is associated with decreased cocaine use in cocaine-dependent patients receiving smoking-cessation treatment .Drug and Alcohol Dependence, ,

Nunes, Edward V; Covey, Lirio S; Brigham, Gregory; Hu, Mei-Chen; Levin, Frances R; Somoza, Eugene C; Winhusen, Theresa M (2013. )Treating nicotine dependence by targeting attention-deficit/ hyperactivity disorder (ADHD) with OROS methylphenidate: the role of baseline ADHD severity and treatment response.The Journal of clinical psychiatry, ,74 (10 ),983-90

Winhusen, Theresa M; Adinoff, Bryon; Lewis, Daniel F; Brigham, Gregory S; Gardin Ii, John G; Sonne, Susan C; Theobald, Jeff; Ghitza, Udi (2013. )A tale of two stimulants: Mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence.Drug and alcohol dependence, ,

Winhusen, Theresa; Walker, Jessica; Brigham, Gregory; Lewis, Daniel; Somoza, Eugene; Theobald, Jeff; Somoza, Veronika (2013. )Preliminary evaluation of a model of stimulant use, oxidative damage and executive dysfunction.The American journal of drug and alcohol abuse, ,39 (4 ),227-34

Somoza, Eugene C; Winship, Douglas; Gorodetzky, Charles W; Lewis, Daniel; Ciraulo, Domenic A; Galloway, Gantt P; Segal, Scott D; Sheehan, Michael; Roache, John D; Bickel, Warren K; Jasinski, Donald; Watson, Donnie W; Miller, Steven R; Somoza, Peggy; Winhusen, Theresa (2013. )A multisite, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of vigabatrin for treating cocaine dependence.JAMA psychiatry (Chicago, Ill.), ,70 (6 ),630-7

Winhusen, Theresa; Lewis, Daniel (2013. )Sex differences in disinhibition and its relationship to physical abuse in a sample of stimulant-dependent patients.Drug and alcohol dependence, ,129 (1-2 ),158-62

Schwartz, Robert P; Stitzer, Maxine L; Feaster, Daniel J; Korthuis, P Todd; Alvanzo, Anika A H; Winhusen, Theresa M; Donnard, Lillian; Snead, Ned; Metsch, Lisa R (2013. )HIV rapid testing in drug treatment: comparison across treatment modalities.Journal of substance abuse treatment, ,44 (4 ),369-74

Westover, Arthur N; Nakonezny, Paul A; Winhusen, Theresa; Adinoff, Bryon; Vongpatanasin, Wanpen (2013. )Risk of methylphenidate-induced prehypertension in normotensive adult smokers with attention deficit hyperactivity disorder.Journal of clinical hypertension (Greenwich, Conn.), ,15 (2 ),124-32

Tamm, Leanne; Trello-Rishel, Kathlene; Riggs, Paula; Nakonezny, Paul A; Acosta, Michelle; Bailey, Genie; Winhusen, Theresa (2013. )Predictors of treatment response in adolescents with comorbid substance use disorder and attention-deficit/hyperactivity disorder.Journal of substance abuse treatment, ,44 (2 ),224-30

Heffner, Jaimee L; Lewis, Daniel F; Winhusen, Theresa M (2013. )Osmotic release oral system methylphenidate prevents weight gain during a smoking-cessation attempt in adults with ADHD.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, ,15 (2 ),583-7

Heffner, Jaimee L; Lewis, Daniel F; Winhusen, Theresa M (2013. )Preliminary evidence that adherence to counseling mediates the effects of pretreatment self-efficacy and motivation on outcome of a cessation attempt in smokers with ADHD.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, ,15 (2 ),393-400

Winhusen, Theresa M; Somoza, Eugene C; Lewis, Daniel F; Kropp, Frankie B; Horigian, Viviana Elizabeth; Adinoff, Bryon (2013. )Frontal systems deficits in stimulant-dependent patients: evidence of pre-illness dysfunction and relationship to treatment response.Drug and alcohol dependence, ,127 (1-3 ),94-100

Kalapatapu, Raj K; Lewis, Daniel F; Vinogradov, Sophia; Batki, Steven L; Winhusen, Theresa (2013. )Relationship of age to impulsivity and decision making: a baseline secondary analysis of a behavioral treatment study in stimulant use disorders.Journal of addictive diseases, ,32 (2 ),206-16

Winstanley, Erin L; Gay, Joe; Roberts, Lisa; Moseley, Judi; Hall, Orman; Beeghly, B Christine; Winhusen, Theresa; Somoza, Eugene (2012. )Prescription drug abuse as a public health problem in Ohio: a case report.Public health nursing (Boston, Mass.), ,29 (6 ),553-62

Ondersma, Steven J; Winhusen, Theresa; Lewis, Daniel F (2012. )Pre-treatment change in a randomized trial with pregnant substance-abusing women in community-based outpatient treatment.Contemporary clinical trials, ,33 (5 ),1074-9

Winhusen, Theresa; Brady, Kathleen T; Stitzer, Maxine; Woody, George; Lindblad, Robert; Kropp, Frankie; Brigham, Gregory; Liu, David; Sparenborg, Steven; Sharma, Gaurav; Vanveldhuisen, Paul; Adinoff, Bryon; Somoza, Eugene (2012. )Evaluation of buspirone for relapse-prevention in adults with cocaine dependence: an efficacy trial conducted in the real world.Contemporary clinical trials, ,33 (5 ),993-1002

Kropp, Frankie; Somoza, Eugene; Lilleskov, Maurine; Moccasin, Mabel Granados-Bad; Moore, Michelle; Lewis, Daniel; Boetel, Brenda; Smith, Corey; Winhusen, Theresa (2012. )Characteristics of Northern Plains American Indians Seeking Substance Abuse Treatment in an Urban, Non-Tribal Clinic: A Descriptive Study.Community mental health journal, ,

Croghan, Ivana T; Trautman, Judith A; Winhusen, Theresa; Ebbert, Jon O; Kropp, Frankie B; Schroeder, Darrell R; Hurt, Richard D (2012. )Tobacco dependence counseling in a randomized multisite clinical trial.Contemporary clinical trials, ,

Campbell, Aimee N C; Nunes, Edward V; Miele, Gloria M; Matthews, Abigail; Polsky, Daniel; Ghitza, Udi E; Turrigiano, Eva; Bailey, Genie L; VanVeldhuisen, Paul; Chapdelaine, Rita; Froias, Autumn; Stitzer, Maxine L; Carroll, Kathleen M; Winhusen, Theresa; Clingerman, Sara; Perez, Livangelie; McClure, Erin; Goldman, Bruce; Crowell, A Rebecca (2012. )Design and methodological considerations of an effectiveness trial of a computer-assisted intervention: an example from the NIDA Clinical Trials Network.Contemporary clinical trials, ,33 (2 ),386-95

Berlin, Ivan; Hu, Mei-Chen; Covey, Lirio S; Winhusen, Theresa (2012. )Attention-deficit/hyperactivity disorder (ADHD) symptoms, craving to smoke, and tobacco withdrawal symptoms in adult smokers with ADHD.Drug and alcohol dependence, ,

Tamm, Leanne; Adinoff, Bryon; Nakonezny, Paul A; Winhusen, Theresa; Riggs, Paula (2012. )Attention-deficit/hyperactivity disorder subtypes in adolescents with comorbid substance-use disorder.The American journal of drug and alcohol abuse, ,38 (1 ),93-100

Winhusen, Theresa; Stitzer, Maxine; Woody, George; Brigham, Gregory; Kropp, Frankie; Ghitza, Udi; Lindblad, Robert; Adinoff, Bryon; Green, Cindy; Sharma, Gaurav; Somoza, Eugene (2012. )Design considerations for a study to evaluate the impact of smoking cessation treatment on stimulant use outcomes in stimulant-dependent individuals.Contemporary clinical trials, ,33 (1 ),197-205

Warden, Diane; Riggs, Paula D; Min, Sung-Joon; Mikulich-Gilbertson, Susan K; Tamm, Leanne; Trello-Rishel, Kathlene; Winhusen, Theresa (2012. )Major depression and treatment response in adolescents with ADHD and substance use disorder.Drug and alcohol dependence, ,120 (1-3 ),214-9

Winhusen, Theresa; Winstanley, Erin L; Somoza, Eugene; Brigham, Gregory (2012. )The potential impact of recruitment method on sample characteristics and treatment outcomes in a psychosocial trial for women with co-occurring substance use disorder and PTSD.Drug and alcohol dependence, ,120 (1-3 ),225-8

Winhusen, Theresa M; Lewis, Daniel F; Riggs, Paula D; Davies, Robert D; Adler, Lenard A; Sonne, Susan; Somoza, Eugene C (2011. )Subjective effects, misuse, and adverse effects of osmotic-release methylphenidate treatment in adolescent substance abusers with attention-deficit/hyperactivity disorder.Journal of child and adolescent psychopharmacology, ,21 (5 ),455-63

Covey, Lirio S; Hu, Mei-Chen; Weissman, Judith; Croghan, Ivana; Adler, Lenard; Winhusen, Theresa (2011. )Divergence by ADHD subtype in smoking cessation response to OROS-methylphenidate.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, ,13 (10 ),1003-8

Covey, Lirio S; Hu, Mei-Chen; Green, Carla A; Brigham, Gregory; Hurt, Richard D; Adler, Lenard; Winhusen, Theresa (2011. )An exploration of site effects in a multisite trial of OROS-methylphenidate for smokers with attention deficit/hyperactivity disorder.The American journal of drug and alcohol abuse, ,37 (5 ),392-9

Greenfield, Shelly F; Rosa, Carmen; Putnins, Susan I; Green, Carla A; Brooks, Audrey J; Calsyn, Donald A; Cohen, Lisa R; Erickson, Sarah; Gordon, Susan M; Haynes, Louise; Killeen, Therese; Miele, Gloria; Tross, Susan; Winhusen, Theresa (2011. )Gender research in the National Institute on Drug Abuse National Treatment Clinical Trials Network: a summary of findings.The American journal of drug and alcohol abuse, ,37 (5 ),301-12

Gray, Kevin M; Riggs, Paula D; Min, Sung-Joon; Mikulich-Gilbertson, Susan K; Bandyopadhyay, Dipankar; Winhusen, Theresa (2011. )Cigarette and cannabis use trajectories among adolescents in treatment for attention-deficit/hyperactivity disorder and substance use disorders.Drug and alcohol dependence, ,117 (2-3 ),242-7

Riggs, Paula D; Winhusen, Theresa; Davies, Robert D; Leimberger, Jeffrey D; Mikulich-Gilbertson, Susan; Klein, Constance; Macdonald, Marilyn; Lohman, Michelle; Bailey, Genie L; Haynes, Louise; Jaffee, William B; Haminton, Nancy; Hodgkins, Candace; Whitmore, Elizabeth; Trello-Rishel, Kathlene; Tamm, Leanne; Acosta, Michelle C; Royer-Malvestuto, Charlotte; Subramaniam, Geetha; Fishman, Marc; Holmes, Beverly W; Kaye, Mary Elyse; Vargo, Mark A; Woody, George E; Nunes, Edward V; Liu, David (2011. )Randomized controlled trial of osmotic-release methylphenidate with cognitive-behavioral therapy in adolescents with attention-deficit/hyperactivity disorder and substance use disorders.Journal of the American Academy of Child and Adolescent Psychiatry, ,50 (9 ),903-14

Covey, Lirio S; Hu, Mei-Chen; Winhusen, Theresa; Weissman, Judith; Berlin, Ivan; Nunes, Edward V (2010. )OROS-methylphenidate or placebo for adult smokers with attention deficit hyperactivity disorder: racial/ethnic differences.Drug and alcohol dependence, ,110 (1-2 ),156-9

Nunes, Edward V; Ball, Samuel; Booth, Robert; Brigham, Gregory; Calsyn, Donald A; Carroll, Kathleen; Feaster, Daniel J; Hien, Denise; Hubbard, Robert L; Ling, Walter; Petry, Nancy M; Rotrosen, John; Selzer, Jeffrey; Stitzer, Maxine; Tross, Susan; Wakim, Paul; Winhusen, Theresa; Woody, George (2010. )Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: have we chosen the best designs?.Journal of substance abuse treatment, ,38 Suppl 1 ,S97-112

Winhusen, Theresa M; Somoza, Eugene C; Brigham, Gregory S; Liu, David S; Green, Carla A; Covey, Lirio S; Croghan, Ivana T; Adler, Lenard A; Weiss, Roger D; Leimberger, Jeffrey D; Lewis, Daniel F; Dorer, Emily M (2010. )Impact of attention-deficit/hyperactivity disorder (ADHD) treatment on smoking cessation intervention in ADHD smokers: a randomized, double-blind, placebo-controlled trial.The Journal of clinical psychiatry, ,

Ondersma, Steven J; Winhusen, Theresa; Lewis, Daniel F (2010. )External pressure, motivation, and treatment outcome among pregnant substance-using women.Drug and alcohol dependence, ,107 (2-3 ),149-53

Kropp, Frankie; Winhusen, Theresa; Lewis, Daniel; Hague, Diane; Somoza, Eugene (2010. )Increasing prenatal care and healthy behaviors in pregnant substance users. Journal of psychoactive drugs, ,42 (1 ),73-81

Brigham, Gregory; Winhusen, Theresa; Lewis, Daniel; Kropp, Frankie (2010. )Incentives for retention of pregnant substance users: a secondary analysis.Journal of substance abuse treatment, ,38 (1 ),90-5

Ondersma, Steven J; Winhusen, Theresa; Erickson, Sarah J; Stine, Susan M; Wang, Yun (2009. )Motivation Enhancement Therapy with pregnant substance-abusing women: does baseline motivation moderate efficacy?.Drug and alcohol dependence, ,101 (1-2 ),74-9

Ziedonis, Douglas M; Amass, Leslie; Steinberg, Marc; Woody, George; Krejci, Jonathan; Annon, Jeffrey J; Cohen, Allan J; Waite-O'Brien, Nancy; Stine, Susan M; McCarty, Dennis; Reid, Malcolm S; Brown, Lawrence S; Maslansky, Robert; Winhusen, Theresa; Babcock, Dean; Brigham, Greg; Muir, Joan; Orr, Deborah; Buchan, Betty J; Horton, Terry; Ling, Walter (2009. )Predictors of outcome for short-term medically supervised opioid withdrawal during a randomized, multicenter trial of buprenorphine-naloxone and clonidine in the NIDA clinical trials network drug and alcohol dependence.Drug and alcohol dependence, ,99 (1-3 ),28-36

Winhusen, Theresa; Kropp, Frankie; Babcock, Dean; Hague, Diane; Erickson, Sarah J; Renz, Connie; Rau, Leela; Lewis, Daniel; Leimberger, Jeff; Somoza, Eugene (2008. )Motivational enhancement therapy to improve treatment utilization and outcome in pregnant substance users.Journal of substance abuse treatment, ,35 (2 ),161-73

Somoza, Eugene; Somoza, Peggy; Lewis, Daniel; Li, Shou-Hua; Winhusen, Theresa; Chiang, Nora; Vocci, Frank; Horn, Paul; Elkashef, Ahmed (2008. )The SRPHK1 outcome measure for cocaine-dependence trials combines self-report, urine benzoylecgonine levels, and the concordance between the two to determine a cocaine-use status for each study day.Drug and alcohol dependence, ,93 (1-2 ),132-40

Winhusen, Theresa; Somoza, Eugene; Ciraulo, Domenic A; Harrer, Judy M; Goldsmith, R Jeffrey; Grabowski, John; Coleman, Florence S; Mindrum, Gordon; Kahn, Roberta; Osman, Sabuhi; Mezinskis, Juris; Li, Shou-Hua; Lewis, Daniel; Horn, Paul; Montgomery, Margaret A; Elkashef, Ahmed (2007. )A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence.Drug and alcohol dependence, ,91 (2-3 ),141-8

Winhusen, Theresa; Somoza, Eugene; Sarid-Segal, Ofra; Goldsmith, R Jeffrey; Harrer, Judy M; Coleman, Florence S; Kahn, Roberta; Osman, Sabuhi; Mezinskis, Juris; Li, Shou-Hua; Lewis, Daniel; Afshar, Maryam; Ciraulo, Domenic A; Horn, Paul; Montgomery, Margaret A; Elkashef, Ahmed (2007. )A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence.Drug and alcohol dependence, ,91 (2-3 ),205-12

Brigham, Gregory S; Amass, Leslie; Winhusen, Theresa; Harrer, Judy M; Pelt, Alvin (2007. )Using buprenorphine short-term taper to facilitate early treatment engagement.Journal of substance abuse treatment, ,32 (4 ),349-56

Winhusen, Theresa; Somoza, Eugene; Singal, Bonita M; Harrer, Judy; Apparaju, Sandhya; Mezinskis, Juris; Desai, Pankaj; Elkashef, Ahmed; Chiang, C Nora; Horn, Paul (2006. )Methylphenidate and cocaine: a placebo-controlled drug interaction study.Pharmacology, biochemistry, and behavior, ,85 (1 ),29-38

Kampman, Kyle M; Leiderman, Deborah; Holmes, Tyson; LoCastro, Joseph; Bloch, Daniel A; Reid, Malcolm S; Shoptaw, Steve; Montgomery, Margaret A; Winhusen, Theresa M; Somoza, Eugene C; Ciraulo, Domenic A; Elkashef, Ahmed; Vocci, Frank (2005. )Cocaine Rapid Efficacy Screening Trials (CREST): lessons learned.Addiction (Abingdon, England), ,100 Suppl 1 ,102-10

Winhusen, Theresa M; Somoza, Eugene C; Harrer, Judy M; Mezinskis, Juris P; Montgomery, Margaret A; Goldsmith, R Jeffrey; Coleman, Florence S; Bloch, Daniel A; Leiderman, Deborah B; Singal, Bonita M; Berger, Paul; Elkashef, Ahmed (2005. )A placebo-controlled screening trial of tiagabine, sertraline and donepezil as cocaine dependence treatments.Addiction (Abingdon, England), ,100 Suppl 1 ,68-77

Berger, S Paul; Winhusen, Theresa M; Somoza, Eugene C; Harrer, Judy M; Mezinskis, Juris P; Leiderman, Deborah B; Montgomery, Margaret A; Goldsmith, R Jeffrey; Bloch, Daniel A; Singal, Bonita M; Elkashef, Ahmed (2005. )A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence.Addiction (Abingdon, England), ,100 Suppl 1 ,58-67

Winhusen, T; Somoza, E; Harrer, J M; Moore, E; Ussery, T; Kropp, F; Singal, B; Elkashef, A; Mojsiak, J (2005. )Metyrapone and cocaine: a double-blind, placebo-controlled drug interaction study.Pharmacology, biochemistry, and behavior, ,80 (4 ),631-8

Amass, Leslie; Ling, Walter; Freese, Thomas E; Reiber, Chris; Annon, Jeffrey J; Cohen, Allan J; McCarty, Dennis; Reid, Malcolm S; Brown, Lawrence S; Clark, Cynthia; Ziedonis, Douglas M; Krejci, Jonathan; Stine, Susan; Winhusen, Theresa; Brigham, Greg; Babcock, Dean; Muir, Joan A; Buchan, Betty J; Horton, Terry (2004. )Bringing buprenorphine-naloxone detoxification to community treatment providers: the NIDA Clinical Trials Network field experience.The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, ,13 Suppl 1 ,S42-66

Somoza, Eugene C; Winhusen, Theresa M; Bridge, T Peter; Rotrosen, John P; Vanderburg, Douglas G; Harrer, Judy M; Mezinskis, Juris P; Montgomery, Margaret A; Ciraulo, Domenic A; Wulsin, Lawson R; Barrett, Jera A (2004. )An open-label pilot study of methylphenidate in the treatment of cocaine dependent patients with adult attention deficit/hyperactivity disorder. Journal of addictive diseases, ,23 (1 ),77-92

Winhusen, Theresa M; Kropp, Frankie (2003. )Psychosocial treatments for women with substance use disorders. Obstetrics and gynecology clinics of North America, ,30 (3 ),483-99, vi

Winhusen, Theresa M; Somoza, Eugene C; Singal, Bonita; Kim, Sunme; Horn, Paul S; Rotrosen, John (2003. )Measuring outcome in cocaine clinical trials: a comparison of sweat patches with urine toxicology and participant self-report. Addiction (Abingdon, England), ,98 (3 ),317-24

Winhusen, T; Somoza, E (2001. )The HPA axis in cocaine use: implications for pharmacotherapy.Journal of addictive diseases, ,20 (3 ),105-19

Winhusen, Theresa; Lewis, Daniel; Adinoff, Bryon; Brigham, Gregory; Kropp, Frankie; Donovan, Dennis M; Seamans, Cindy L; Hodgkins, Candace C; Dicenzo, Jessica C; Botero, Christopher L; Jones, Davina R; Somoza, Eugene Impulsivity is associated with treatment non-completion in cocaine- and methamphetamine-dependent patients but differs in nature as a function of stimulant-dependence diagnosis.Journal of substance abuse treatment, ,44 (5 ),541-7

Covey, Lirio S; Hu, Mei-Chen; Winhusen, Theresa; Lima, Jennifer; Berlin, Ivan; Nunes, Edward (2015. )Anxiety and Depressed Mood Decline Following Smoking Abstinence in Adult Smokers with Attention Deficit Hyperactivity Disorder.Journal of substance abuse treatment, ,59 ,104-8

Wilder, Christine M; Miller, Shannon C; Tiffany, Elizabeth; Winhusen, Theresa; Winstanley, Erin L; Stein, Michael D (2015. )Risk Factors for Opioid Overdose and Awareness of Overdose Risk Among Veterans Prescribed Chronic Opioids for Addiction or Pain.Journal of addictive diseases, ,0

Westover, Arthur N; Kashner, T Michael; Winhusen, Theresa M; Golden, Richard M; Nakonezny, Paul A; Adinoff, Bryon; Henley, Steven S (2015. )A systematic approach to subgroup analyses in a smoking cessation trial.The American journal of drug and alcohol abuse, ,41 (6 ),498-507

Magee, Joshua C; Winhusen, Theresa (2015. )The Coupling of Nicotine and Stimulant Craving During Treatment for Stimulant Dependence.Journal of consulting and clinical psychology, ,

Wilder, Christine M; Winhusen, Theresa (2015. )Pharmacological Management of Opioid Use Disorder in Pregnant Women.CNS drugs, ,29 (8 ),625-36

Magee, Joshua C; Lewis, Daniel F; Winhusen, Theresa (2015. )Evaluating Nicotine Craving, Withdrawal, and Substance Use as Mediators of Smoking Cessation in Cocaine- and Methamphetamine-Dependent Patients.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, ,

Luo, Sean X; Covey, Lirio S; Hu, Mei-Chen; Levin, Frances R; Nunes, Edward V; Winhusen, Theresa M (2015. )Toward personalized smoking-cessation treatment: Using a predictive modeling approach to guide decisions regarding stimulant medication treatment of attention-deficit/hyperactivity disorder (ADHD) in smokers.The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, ,24 (4 ),348-56

McClure, Erin A; Campbell, Aimee N C; Pavlicova, Martina; Hu, Meichen; Winhusen, Theresa; Vandrey, Ryan G; Ruglass, Lesia M; Covey, Lirio S; Stitzer, Maxine L; Kyle, Tiffany L; Nunes, Edward V (2015. )Cigarette Smoking During Substance Use Disorder Treatment: Secondary Outcomes from a National Drug Abuse Treatment Clinical Trials Network study.Journal of substance abuse treatment, ,53 ,39-46

Wilder, Christine; Lewis, Daniel; Winhusen, Theresa (2015. )Medication assisted treatment discontinuation in pregnant and postpartum women with opioid use disorder.Drug and alcohol dependence, ,149 ,225-31

LoBue, Christian; Cullum, C Munro; Braud, Jacqueline; Walker, Robrina; Winhusen, Theresa; Suderajan, Prabha; Adinoff, Bryon (2014. )Optimal neurocognitive, personality and behavioral measures for assessing impulsivity in cocaine dependence.The American journal of drug and alcohol abuse, ,40 (6 ),455-62

McClure, Erin A; Sonne, Susan C; Winhusen, Theresa; Carroll, Kathleen M; Ghitza, Udi E; McRae-Clark, Aimee L; Matthews, Abigail G; Sharma, Gaurav; Van Veldhuisen, Paul; Vandrey, Ryan G; Levin, Frances R; Weiss, Roger D; Lindblad, Robert; Allen, Colleen; Mooney, Larissa J; Haynes, Louise; Brigham, Gregory S; Sparenborg, Steve; Hasson, Albert L; Gray, Kevin M (2014. )Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network.Contemporary clinical trials, ,39 (2 ),211-23

Walker, Jessica; Winhusen, Theresa; Storkson, Jayne M; Lewis, Daniel; Pariza, Michael W; Somoza, Eugene; Somoza, Veronika (2014. )Total antioxidant capacity is significantly lower in cocaine-dependent and methamphetamine-dependent patients relative to normal controls: results from a preliminary study.Human psychopharmacology, ,29 (6 ),537-43

Winhusen, Theresa; Wilder, Christine; Wexelblatt, Scott L; Theobald, Jeffrey; Hall, Eric S; Lewis, Daniel; Van Hook, James; Marcotte, Michael (2014. )Design considerations for point-of-care clinical trials comparing methadone and buprenorphine treatment for opioid dependence in pregnancy and for neonatal abstinence syndrome.Contemporary clinical trials, ,39 (1 ),158-65

Winhusen, Theresa (2014. )Not getting lost in translational science: A tool for navigating the pre-implementation phase of multi-site pharmacological clinical trials. Applied clinical trials, ,23 (8-9 ),36-39

Winhusen, Theresa M; Lewis, Daniel F; Somoza, Eugene C; Horn, Paul (2014. )Pharmacodynamics must inform statistics: an example from a cocaine dependence pharmacotherapy trial.ISRN Addiction, ,2014 ,927290

Winhusen, Theresa M; Somoza, Eugene C; Lewis, Daniel F; Kropp, Frankie; Theobald, Jeff; Elkashef, Ahmed (2014. )An Evaluation of Substance Abuse Treatment and HIV Education on Safe Sex Practices in Cocaine Dependent Individuals.ISRN Addiction, ,2014 ,912863

Winhusen, T; Theobald, J; Lewis, D; Wilder, C M; Lyons, M S (2016. )Development and initial testing of a tailored telephone intervention delivered by peers to prevent recurring opioid-overdoses (TTIP-PRO).Health education research, ,31 (2 ),146-60

Winhusen, Theresa; Theobald, Jeffrey; Lewis, Daniel (2016. )Design considerations for a pilot trial using a novel approach for evaluating smoking-cessation medication in methadone-maintained smokers.Contemporary clinical trials, ,47 ,334-9

Adinoff, Bryon; Carmody, Thomas J; Walker, Robrina; Donovan, Dennis M; Brigham, Gregory S; Winhusen, Theresa M (2016. )Decision-making processes as predictors of relapse and subsequent use in stimulant-dependent patients.The American journal of drug and alcohol abuse, ,42 (1 ),88-97

Montgomery, LaTrice; Mantey, Dale S; Peters, Erica N; Herrmann, Evan S; Winhusen, Theresa (2020. )Blunt use and menthol cigarette smoking: An examination of adult marijuana users.Addictive behaviors, ,102 ,106153

Winhusen, Theresa; Theobald, Jeff; Kaelber, David C; Lewis, Daniel (2019. )The association between regular cannabis use, with and without tobacco co-use, and adverse cardiovascular outcomes: cannabis may have a greater impact in non-tobacco smokers.The American journal of drug and alcohol abuse, ,1-8

Luo, Sean X; Covey, Lirio S; Hu, Mei-Chen; Winhusen, Theresa M; Nunes, Edward V (2019. )Differential Posttreatment Outcomes of Methylphenidate for Smoking Cessation for Individuals With ADHD.The American journal on addictions, ,28 (6 ),497-502

Winhusen, Theresa; Theobald, Jeff; Kaelber, David C; Lewis, Daniel (2019. )Regular cannabis use, with and without tobacco co-use, is associated with respiratory disease.Drug and alcohol dependence, ,204 ,107557

Winhusen, Theresa; Theobald, Jeff; Kaelber, David C; Lewis, Daniel (2019. )Medical complications associated with substance use disorders in patients with type 2 diabetes and hypertension: electronic health record findings.Addiction (Abingdon, England), ,114 (8 ),1462-1470

Montgomery, LaTrice; McClure, Erin A; Tomko, Rachel L; Sonne, Susan C; Winhusen, Theresa; Terry, Garth E; Grossman, Jason T; Gray, Kevin M (2019. )Blunts versus joints: Cannabis use characteristics and consequences among treatment-seeking adults.Drug and alcohol dependence, ,198 ,105-111

Winhusen, Theresa M; Theobald, Jeff; Lewis, Daniel F (2019. )Substance use outcomes in cocaine-dependent tobacco smokers: A mediation analysis exploring the role of sleep disturbance, craving, anxiety, and depression.Journal of substance abuse treatment, ,96 ,53-57

Winhusen, Theresa; Feaster, Daniel J; Duan, Rui; Brown, Jennifer L; Daar, Eric S; Mandler, Raul; Metsch, Lisa R (2018. )Baseline Cigarette Smoking Status as a Predictor of Virologic Suppression and CD4 Cell Count During One-Year Follow-Up in Substance Users with Uncontrolled HIV Infection.AIDS and behavior, ,22 (6 ),2026-2032

Aharonovich, Efrat; Campbell, Aimee N C; Shulman, Matisyahu; Hu, Mei-Chen; Kyle, Tiffany; Winhusen, Theresa; Nunes, Edward V Neurocognitive Profiling of Adult Treatment Seekers Enrolled in a Clinical Trial of a Web-delivered Intervention for Substance Use Disorders.Journal of addiction medicine, ,12 (2 ),99-106

Luo, Sean X; Wall, Melanie; Covey, Lirio; Hu, Mei-Chen; Scodes, Jennifer M; Levin, Frances R; Nunes, Edward V; Winhusen, Theresa (2018. )Exploring longitudinal course and treatment-baseline severity interactions in secondary outcomes of smoking cessation treatment in individuals with attention-deficit hyperactivity disorder.The American journal of drug and alcohol abuse, ,44 (6 ),653-659

Brown, Jennifer L; Winhusen, Theresa; DiClemente, Ralph J; Sales, Jessica M; Rose, Eve S; Safonova, Polina; Levina, Olga; Belyakov, Nikolay; Rassokhin, Vadim V (2017. )The association between cigarette smoking, virologic suppression, and CD4+ lymphocyte count in HIV-Infected Russian women.AIDS care, ,29 (9 ),1102-1106

Wilder, Christine M; Hosta, Daniel; Winhusen, Theresa (2017. )Association of methadone dose with substance use and treatment retention in pregnant and postpartum women with opioid use disorder.Journal of substance abuse treatment, ,80 ,33-36

Osterman, Robin; Lewis, Daniel; Winhusen, Theresa (2017. )Efficacy of motivational enhancement therapy to decrease alcohol and illicit-drug use in pregnant substance users reporting baseline alcohol use.Journal of substance abuse treatment, ,77 ,150-155

Brown, Jennifer L; Gause, Nicole K; Lewis, Daniel; Winhusen, Theresa (2017. )Examination of the Hepatitis C Virus care continuum among individuals with an opioid use disorder in substance use treatment.Journal of substance abuse treatment, ,76 ,77-80

Winhusen, Theresa (2017. )Introduction to Special Issue on Tobacco and Other Substance Use Disorders: Links and Implications.The American journal of drug and alcohol abuse, ,43 (2 ),129-131

Winhusen, Theresa; Lewis, Daniel Cigarette smoking in pregnant substance users: Association with substance use and desire to quit.Journal of addictive diseases, ,36 (1 ),88-91

Kropp, Frankie; Lewis, Daniel; Winhusen, Theresa (2017. )The Effectiveness of Ultra-Low Magnitude Reinforcers: Findings From a "Real-World" Application of Contingency Management.Journal of substance abuse treatment, ,72 ,111-116

Winhusen, Theresa; Lofwall, Michelle; Jones, Hendrée E; Wilder, Christine; Lindblad, Robert; Schiff, Davida M; Wexelblatt, Scott; Merhar, Stephanie; Murphy, Sean M; Greenfield, Shelly F; Terplan, Mishka; Wachman, Elisha M; Kropp, Frankie; Theobald, Jeff; Lewis, Mitra; Matthews, Abigail G; Guille, Connie; Silverstein, Michael; Rosa, Carmen (2020. )Medication treatment for opioid use disorder in expectant mothers (MOMs): Design considerations for a pragmatic randomized trial comparing extended-release and daily buprenorphine formulations.Contemporary clinical trials, ,106014

Winhusen, Theresa; Theobald, Jeff; Kaelber, David C; Lewis, Daniel (2020. )The association between regular cocaine use, with and without tobacco co-use, and adverse cardiovascular and respiratory outcomes.Drug and alcohol dependence, ,214 ,108136

Winhusen, Theresa; Wilder, Christine; Kropp, Frankie; Theobald, Jeff; Lyons, Michael S; Lewis, Daniel (2020. )A brief telephone-delivered peer intervention to encourage enrollment in medication for opioid use disorder in individuals surviving an opioid overdose: Results from a randomized pilot trial.Drug and alcohol dependence, ,216 ,108270

Winhusen, Theresa; Wilder, Christine; Lyons, Michael S; Theobald, Jeff; Kropp, Frankie; Lewis, Daniel (2020. )Evaluation of a personally-tailored opioid overdose prevention education and naloxone distribution intervention to promote harm reduction and treatment readiness in individuals actively using illicit opioids.Drug and alcohol dependence, ,216 ,108265

Montgomery, LaTrice; Plano Clark, Vicki L; Twitty, Dylanne; Budney, Alan J; Prochaska, Judith J; Winhusen, Theresa (2020. )Is it "loud" enough?: A qualitative investigation of blunt use among African American young adults.Journal of ethnicity in substance abuse, ,1-15

Winhusen, Theresa; Theobald, Jeff; Kaelber, David C; Lewis, Daniel (2020. )Increased Morbidity and Mortality in Hypertensive Patients With Substance Use Disorders: Electronic Health Record Findings. Journal of studies on alcohol and drugs, ,81 (4 ),471-478

Honors and Awards

1988 Psi Chi (National Psychology Honorary) Induction

1989 Psi Chi Distinguished Service Award University of Cincinnati

1989 -1990 President of Psi Chi: University of Cincinnati Chapter Cincinnati, Ohio

1990 Doris Twitchell Allen Award: Outstanding Senior Woman University of Cincinnati Psychology Department, Cincinnati, Ohio

1990 Phi Beta Kappa Induction

1991 Indiana University Graduate Fellowship Bloomington, IN

1991 -1993 Predoctoral NIMH Research Traineeship

1993 -1994 Drolet Summer Fellowship to conduct research on depression Bloomington, IN

1994 Indiana University Graduate Doctoral Grant-In-Aid of Research Bloomington, IN

2006 Faculty Achievement in Research Award Cincinnati, Ohio University of Cincinnati College of Medicine

2010 National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) Besteman Award First recipient of this award, which is given for outstanding contributions to CTN's mission - presented by Dr. Nora Volkow, NIDA Director

Service

(NIDA Clinical Trials Network Training Subcommittee )Committee Chair 2001 -2002

Drug and Alcohol Dependence Reviewer 2005 -To Present

Human Psychopharmacology: Clinical and Experimental Reviewer 2005 -To Present

Journal of Clinical Psychiatry Reviewer 2005 -To Present

Journal of Pharmacology and Experimental Therapeutics Reviewer 2005 -To Present

Journal of Substance Abuse Treatment Reviewer 2005 -To Present

Psychological Assessment Reviewer 2005 -To Present

(Pre-Review of Medical Protocols Committee )Member 2010 -To Present

(ZDA1 JXR-D (10) Special Emphasis Panel )Member 2010

(ZDA1 JXR-D (09) Special Emphasis Panel )Member 2010

(Executive Committee of the Center for Treatment, Research, & Education in Addictive Disorders (CeTREAD) )Member 2010 -To Present

Post Graduate Training and Education

05-2003Motivational Interviewing with Pregnant Substance Abusers, (Instructor: Nancy Handmaker, Ph.D.), University of New Mexico, ,Albuquerque, New Mexico

2001Basic Clinical training in Motivational Interviewing, (Instructor: Jan Dyehouse, Ph.D.), 2 day training, University of Cincinnati, ,Cincinnati, Ohio

1999Basic Training Course for New Clinical Statisticians, Pharmaceutical Education & Research Institute, Inc. (PERI), Orlando, Florida

1996Basic Clinical training in Cognitive Behavioral Therapy for Substance Abusers, (Instructor: Kathy Carroll, Ph.D.), 2 day training, Yale University, ,Boston, MA

Professional Affiliation

2010 -To Present: Regular Member College on Problems of Drug Dependence (CPDD),

2012 -To Present: Society for Research on Nicotine and Tobacco- Full Member

Contact Information

Research - Medical Office Building East
3131 Harvey Avenue, Suite 104
Cincinnati  Ohio, 45229
Phone: 513-585-8292
Fax: 513-585-8278
winhust@ucmail.uc.edu