Peng V. Wu

S.B.: Massachusetts Institute of Technology Cambridge, MA, 2004 (Chemistry, Biology, Literature (minor))

Ph.D.: The Rockefeller University New York, NY, 2012 (Cell Biology/Genetics)

M.D.: Weill Cornell Medical College New York, NY, 2013

Grant: #1189428.01 2024 -2029 Burroughs Wellcome Fund Career Award for Medical Scientists Lineage programs that promote tumorigenesis in the developing liver Role:Principal Investigator 700,000 Active Type:Grant

Peer Reviewed Publications

Wu, Peng V; Fish, Matt; Hazard, Florette K; Zhu, Chunfang; Vennam, Sujay; Walton, Hannah; Wagh, Dhananjay; Coller, John; Przybyl, Joanna; Morri, Maurizio; Neff, Norma; West, Robert B; Nusse, Roel (2024. ) A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma.Nature communications, , 15 (1 ) ,10007 More Information

Bouju, Agathe; Nusse, Roel; Wu, Peng V (2024. ) A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15.Differentiation; research in biological diversity, , 100816 More Information

Myler, Logan R; Toia, Beatrice; Vaughan, Cara K; Takai, Kaori; Matei, Andreea M; Wu, Peng; Paull, Tanya T; de Lange, Titia; Lottersberger, Francisca (2023. ) DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres.Nature structural & molecular biology, , 30 (9 ) ,1346-1356 More Information

Sarkar, Abby; Jin, Yinhua; DeFelice, Brian C; Logan, Catriona Y; Yang, Yan; Anbarchian, Teni; Wu, Peng; Morri, Maurizio; Neff, Norma F; Nguyen, Huy; Rulifson, Eric; Fish, Matthew; Kaye, Avi Gurion; Martínez Jaimes, Azalia M; Nusse, Roel (2023. ) Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver.eLife, , 12 , More Information

Wu, Peng V; Rangaswami, Arun (2022. ) Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy.Current oncology reports, , 24 (9 ) ,1209-1218 More Information

Jin, Yinhua; Anbarchian, Teni; Wu, Peng; Sarkar, Abby; Fish, Matt; Peng, Weng Chuan; Nusse, Roel (2022. ) Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade.Proceedings of the National Academy of Sciences of the United States of America, , 119 (30 ) ,e2203849119 More Information

Wu, Peng V; Nusse, Roel (2022. ) 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids.Methods in molecular biology (Clifton, N.J.), , 2544 ,259-267 More Information

Peng, Weng Chuan; Logan, Catriona Y; Fish, Matt; Anbarchian, Teni; Aguisanda, Francis; Álvarez-Varela, Adrián; Wu, Peng; Jin, Yinhua; Zhu, Junjie; Li, Bin; Grompe, Markus; Wang, Bruce; Nusse, Roel (2018. ) Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture.Cell, , 175 (6 ) ,1607-1619.e15 More Information

Wu, Peng; Takai, Hiroyuki; de Lange, Titia (2012. ) Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.Cell, , 150 (1 ) ,39-52 More Information

Wu, Peng; van Overbeek, Megan; Rooney, Sean; de Lange, Titia (2010. ) Apollo contributes to G overhang maintenance and protects leading-end telomeres.Molecular cell, , 39 (4 ) ,606-17 More Information

Wu, Peng; de Lange, Titia (2009. ) Human telomerase caught in the act.Cell, , 138 (3 ) ,432-4 More Information

Wu, Peng; de Lange, Titia (2008. ) No overt nucleosome eviction at deprotected telomeres.Molecular and cellular biology, , 28 (18 ) ,5724-35 More Information

2022 William Guy Forbeck Scholar Award William Guy Forbeck Research Foundation

2021 Damon Runyon-Jake Wetchler Award for Pediatric Innovation Jake Wetchler Foundation/Damon Runyon Cancer Research Foundation

2013-2016 Residency (General Pediatrics), UCSF, , San Francisco, CA

2016-2019 Fellowship (Pediatric Hematology/Oncology), Stanford University, , Palo Alto, CA