Peng V. Wu

S.B.: Massachusetts Institute of Technology Cambridge, MA, 2004 (Chemistry, Biology, Literature (minor))

Ph.D.: The Rockefeller University New York, NY, 2012 (Cell Biology/Genetics)

M.D.: Weill Cornell Medical College New York, NY, 2013

09-01-2024 -08-31-2029 Burroughs Wellcome Fund Career Award for Medical Scientists Lineage programs that promote tumorigenesis in the developing liver Role:Principal Investigator Active Type:Grant

01-01-2025 -12-31-2025 Hyundai Hope on Wheels Bridge2K Mechanisms of tumor suppression in the developing liver Role:Principal Investigator Active Type:Grant

Peer Reviewed Publications

Wu, Peng V; Fish, Matt; Hazard, Florette K; Zhu, Chunfang; Vennam, Sujay; Walton, Hannah; Wagh, Dhananjay; Coller, John; Przybyl, Joanna; Morri, Maurizio; Neff, Norma; West, Robert B; Nusse, Roel  (2024). A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature communications, 15 (1) , 10007More Information

Bouju, Agathe; Nusse, Roel; Wu, Peng V  (2024). A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15. Differentiation; research in biological diversity, 100816More Information

Myler, Logan R; Toia, Beatrice; Vaughan, Cara K; Takai, Kaori; Matei, Andreea M; Wu, Peng; Paull, Tanya T; de Lange, Titia; Lottersberger, Francisca  (2023). DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres. Nature structural & molecular biology, 30 (9) , 1346-1356More Information

Sarkar, Abby; Jin, Yinhua; DeFelice, Brian C; Logan, Catriona Y; Yang, Yan; Anbarchian, Teni; Wu, Peng; Morri, Maurizio; Neff, Norma F; Nguyen, Huy; Rulifson, Eric; Fish, Matthew; Kaye, Avi Gurion; Martínez Jaimes, Azalia M; Nusse, Roel  (2023). Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. eLife, 12More Information

Wu, Peng V; Rangaswami, Arun  (2022). Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy. Current oncology reports, 24 (9) , 1209-1218More Information

Jin, Yinhua; Anbarchian, Teni; Wu, Peng; Sarkar, Abby; Fish, Matt; Peng, Weng Chuan; Nusse, Roel  (2022). Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade. Proceedings of the National Academy of Sciences of the United States of America, 119 (30) , e2203849119More Information

Wu, Peng V; Nusse, Roel  (2022). 3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids. Methods in molecular biology (Clifton, N.J.), 2544, 259-267More Information

Peng, Weng Chuan; Logan, Catriona Y; Fish, Matt; Anbarchian, Teni; Aguisanda, Francis; Álvarez-Varela, Adrián; Wu, Peng; Jin, Yinhua; Zhu, Junjie; Li, Bin; Grompe, Markus; Wang, Bruce; Nusse, Roel  (2018). Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell, 175 (6) , 1607-1619.e15More Information

Wu, Peng; Takai, Hiroyuki; de Lange, Titia  (2012). Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell, 150 (1) , 39-52More Information

Wu, Peng; van Overbeek, Megan; Rooney, Sean; de Lange, Titia  (2010). Apollo contributes to G overhang maintenance and protects leading-end telomeres. Molecular cell, 39 (4) , 606-17More Information

Wu, Peng; de Lange, Titia  (2009). Human telomerase caught in the act. Cell, 138 (3) , 432-4More Information

Wu, Peng; de Lange, Titia  (2008). No overt nucleosome eviction at deprotected telomeres. Molecular and cellular biology, 28 (18) , 5724-35More Information

2022 William Guy Forbeck Scholar Award William Guy Forbeck Research Foundation

2021 Damon Runyon-Jake Wetchler Award for Pediatric Innovation Jake Wetchler Foundation/Damon Runyon Cancer Research Foundation

2013-2016 Residency (General Pediatrics), University of California, San Francisco, , CA

2016-2019 Fellowship (Pediatric Hematology/Oncology), Stanford University, , CA

2019-2024 Instructor/Postdoctoral Fellow (Nusse Lab), Department of Developmental Biology, Department of Pediatrics (Hematology/Oncology), Stanford University, , CA