Changchun Xie, PhD

Ph.D.: University of Guelph Canada, 2003 (Statistics)

M.S.: Dalhousie University Canada, 1999 (Statistics)

M.S.: Zhejiang University China, 1992 (Mathematical statistics)

B.S.: Hunan Normal University China, 1989 (Mathematics)

My research interests include
1) clinical trials,
2) statistical genetics: next generation sequencing, Genome-wide association study, NDA methylation, gene environmental interaction,
3) statistical methodology: survival  models, multiple testing, hierarchical generalized linear models, nonparametric methods, longitudinal data and multivariate statistical analysis.

2001 -2001 Biostatistician, • Developed a new statistical method for bioavailability and bioequivalence analysis • Updated SAS program for analysis of bioavailability and bioequivalence studies , Therapeutic Products Directorate, Health Products and Food Branch, Health Canada, Ottawa, Canada

2002 -2007 Senior Statistical Analyst/Programmer, • Developing new statistical methods for analyzing multicentre clinical trials • Analyzing and publishing the results of Clinical Trials • Combining two large multicentre international clinical trials • Developing/validating SAS/SAS macro programs for large data management and statistical analysis • Developed practical Output Delivery System (ODS) Techniques for systematically and automatically generating high quality DSMB reports • Developing genetic statistical methods and analyzing large genetic data , PHRI, Department of Medicine, McMaster University, Hamilton, Canada

2007 -2012 Senior Statistical Analyst, • Supervising biostatisticians and senior biostatisticians in clinical trials, genetic studies and epidemiology studies • Developing new statistical methods for analyzing multicentre clinical trials • Developing genetic statistical methods and analyzing large genetic data • Analyzing and publishing the results of clinical trials • Preparing DSMB • Organizing regular statistical seminars , PHRI, Department of Medicine, McMaster University, Hamilton, Canada

2009 -2012 Assistant Professor, • Teaching in the Health Research Methodology Graduate Program • Teaching in the Population Genomics Program • Supervising Master/PhD students , Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada

2012 -2015 Assistant Professor(tenure-track), • Teaching biostatistics courses • Supervising Master/PhD students • Statistical consulting (Clinical trials, epidemiology and genetic studies) • Reviewing grant proposals • DSMB member for Clinical trials • UC IRB Committee member • Protocol Review and Monitoring Committee member in UC Cancer Institute and UC Health , Department of Environmental Health, University of Cincinnati, Cincinnati, USA

2015 -2018 Associate Professor, • Teaching biostatistics courses • Supervising Master/PhD students • Statistical consulting (Clinical trials, epidemiology and genetic studies) • Reviewing grant proposals • DSMB member for Clinical trials • UC IRB Committee member • Protocol Review and Monitoring Committee member in UC Cancer Institute and UC Health , Department of Environmental Health, University of Cincinnati, Cincinnati, USA

2018 - Professor, • Co-PI/Co-I for multiple grants • Teaching biostatistics courses • Supervising Master/PhD students • Statistical consulting (Clinical trials, epidemiology and genetic studies) • Reviewing grant proposals • DSMB member for Clinical trials • UC IRB Committee member • Protocol Review and Monitoring Committee member in UC Cancer Institute and UC Health , Department of Environmental Health, University of Cincinnati, Cincinnati, USA

Grant: #R21ES024717 Investigators:Bhattacharya, Amit; Haynes, Erin; Heineman, William; Papautsky, Ian; Wilsey, Philip; Xie, Changchun 03-01-2015 -02-28-2017 National Institute of Environmental Health Sciences Validation and Demonstration of Point-of-Care Sensor for Multi-Metal Exposure Assessment Role:Collaborator $197,708.00 Awarded Level:Federal

Grant: #R21NS093493-01 Investigators:Hao, Jiukuan; Xie, Changchun 06-01-2015 -05-31-2017 National Institute of Neurological Disorders and Stroke Application of Brain-Targeted Anti-inflammatory RNA Nanoparticle for Ischemic Stroke Therapy Role:Collaborator $205,506.00 Awarded Level:Federal

Grant: #R01DK105379 Investigators:Attari, Mehran; Salehi, Marzieh; Xie, Changchun 07-01-2015 -05-31-2020 National Inst of Diabetes and Digestive and Kidney Disease The weight-independent effects of bariatric surgeries on islet cell function Role:Collaborator $555,488.00 Awarded Level:Federal

Grant: #RC105513UC/U01ES026119 Investigators:Pinney, Susan; Xie, Changchun 09-30-2015 -06-30-2020 National Institute of Environmental Health Sciences Mammary carcinogenesis: pubertal and adult effects of high fat diet+oxybenzone Role:Collaborator $35,343.00 Awarded Level:Federal

Grant: #Harry J. Lloyd Charitable Trust 2015-17 Investigators:Abdelmalek, Zalfa; Xie, Changchun; Zhang, Yuhang 06-01-2015 -05-31-2017 Harry J. Lloyd Charitable Trust Reprogramming the Tumor Microenvironment to Treat Melanoma Role:Collaborator $200,000.00 Active Level:Private Non-Profit

Grant: #UM1DK095710 Investigators:Xie, Changchun 09-01-2016 -08-31-2021 National Inst of Diabetes and Digestive and Kidney Disease Continuation of Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS), Biostatistics Research Center Role:PI $1,066,072.00 Active Level:Federal

Grant: #136802 / R01 HL132344 Investigators:Xie, Changchun 04-01-2016 -03-31-2021 National Heart, Lung and Blood Institute Unraveling ancestry and environmental exposure interactions in childhood asthma Role:PI $26,569.00 Active Level:Federal

Grant: #ES028277 Investigators:Chen, Aimin; Dietrich, Kim; Xie, Changchun 09-30-2017 -06-30-2022 National Institute of Environmental Health Sciences Developmental neurotoxicity of organophosphate and novel brominated flame retardants in children Role:Collaborator $664,377.00 Awarded Level:Federal

Grant: #R01ES027855 Investigators:Pinney, Susan; Rubinstein, Jack; Wang, Hongsheng; Xie, Changchun 02-01-2018 -01-31-2023 National Institute of Environmental Health Sciences Endocrine Disruptors and Heart Health Role:Collaborator $429,032.00 Active Level:Federal

Grant: #R01ES029133 Investigators:Chen, Aimin; Pinney, Susan; Xie, Changchun 08-15-2018 -06-30-2021 National Institute of Environmental Health Sciences Longitudinal study of endocrine disrupting chemical exposure and the early hormonal milieu of girls around the time of thelarche Role:Collaborator $394,749.00 Active Level:Federal

Grant: #R24ES028527 Investigators:Leung, Yuet Kin; Pinney, Susan; Reichard, John; Xie, Changchun 09-30-2018 -06-30-2023 National Institute of Environmental Health Sciences Fernald Community Cohort: Research Resource for Environmental Epidemiology Role:Collaborator $399,875.00 Active Level:Federal

Grant: #R01AR077238 Investigators:Supp, Dorothy; Xie, Changchun; Zhang, Yuhang 02-04-2021 -11-30-2025 National Institute of Arthritis, Musculoskeletal and Skin Disease Multiscale modeling of an inductive hair follicle microenvironment in engineered skin substitute Role:Collaborator $364,613.00 Awarded Level:Federal

Grant: #R01AR077238 Investigators:Supp, Dorothy; Xie, Changchun; Zhang, Yuhang 02-01-2021 -11-30-2025 National Institute of Arthritis, Musculoskeletal and Skin Disease Multiscale modeling of an inductive hair follicle microenvironment in engineered skin substitute Role:Collaborator $364,613.00 Awarded Level:Federal

Grant: #R01 DC009435 Investigators:Farbos de Luzan, Charles; Gutmark, Ephraim; Khosla, Siddarth; Oren, Liran; Xie, Changchun 04-01-2021 -03-31-2026 National Institute on Deafness and Other Communication Disor The Relationship Between Vortices, Acoustics, and Vibration in Vocal Fold Asymmetries Role:Collaborator 632470.00 Hold Level:Federal

Grant: #580431 / R01ES028277 Investigators:Xie, Changchun 04-19-2021 -12-31-2021 National Institute of Environmental Health Sciences DEVELOPMENTAL NEUROTOXICITY OF ORGANOPHOSPHATE AND NOVEL BROMINATED FLAME RETARDANTS IN CHILDREN Role:PI 51303.00 Active Level:Federal

Grant: #R01CA249737 Investigators:Abdelmalek, Zalfa; Chaudhary, Rekha; Harris, Gregory; Xie, Changchun; Zhang, Yuhang 06-15-2021 -05-31-2026 National Cancer Institute Reprogramming of the stromal microenvironment in melanoma progression and therapeutic escape Role:Collaborator 375431.00 Awarded Level:Federal

Grant: #R21ES032112 Investigators:Pinney, Susan; Thomas, Michael; Xie, Changchun 07-18-2022 -06-30-2024 National Institute of Environmental Health Sciences Uranium Exposure and Infertility in Reproductive Partners in the Fernald Community Cohort Role:Collaborator 258577.00 Awarded Level:Federal

Grant: #R01HL168588 Investigators:Borchers, Michael; Kotagiri, Nalinikanth; McCormack, Francis; Weiss, Alison; Xie, Changchun 07-01-2023 -06-30-2028 National Heart, Lung and Blood Institute Siderophore based molecular imaging of pulmonary infections Role:Collaborator 678865.00 Awarded Level:Federal

Grant: #R01CA279962 JIT Investigators:Desai, Pankaj; Faber, Ed; Kotagiri, Nalinikanth; Sertorio, Mathieu; Xie, Changchun 12-01-2023 -11-30-2028 National Cancer Institute Genetically-encoded molecular imaging of genome-edited immune cells Role:Collaborator 0.00 Hold Level:Federal

Grant: #OS00001064 04-01-2025 -03-31-2030 Cincinnati Children's Hospital Medical Center Integrative Neurodevelopmental Approach to Cerebral Vision Impairment (CVI): Screening and Subtyping in Early Childhood Role:PI 36746.00 Awarded Level:Non Profit

Grant: #OS00001064 04-01-2025 -03-31-2030 Cincinnati Children's Hospital Medical Center Integrative Neurodevelopmental Approach to Cerebral Vision Impairment (CVI): Screening and Subtyping in Early Childhood Role:PI 36746.00 Awarded Level:Non Profit

Peer Reviewed Publications

Chen, Yaolong; Yang, Kehu; Jing, Tao; Tian, Jinhui; Shen, Xiping; Xie, Changchun; Ma, Bin; Liu, Yali; Yao, Liang; Cao, Xiaoyuan  (2014). Use of text messages to communicate clinical recommendations to health workers in rural China: a cluster-randomized trial. Bulletin of the World Health Organization, 92 (7) , 474-81More Information

Bailey, Swneke D; Xie, Changchun; Paré, Guillaume; Montpetit, Alexandre; Mohan, Viswanathan; Yusuf, Salim; Gerstein, Hertzel; Engert, James C; Anand, Sonia S  (2014). Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI. Diabetologia, 57 (4) , 738-45More Information

Xie, Changchun  (2014). Relations among Three Parametric Multiple Testing Methods for Correlated Tests. Journal of statistical computation and simulation, 84 (4) , 812-818More Information

Zhou, Tao; Li, Xia; Tang, Zhe; Xie, Changchun; Tao, Lixin; Pan, Lei; Huo, Da; Sun, Fei; Luo, Yanxia; Wang, Wei; Yan, Aoshuang; Guo, Xiuhua  (2014). Risk factors of CVD mortality among the elderly in Beijing, 1992 - 2009: an 18-year cohort study. International journal of environmental research and public health, 11 (2) , 2193-208More Information

Tang, Zhe; Zhou, Tao; Luo, Yanxia; Xie, Changchun; Huo, Da; Tao, Lixin; Pan, Lei; Sun, Fei; Zhu, Huiping; Yang, Xinghua; Wang, Wei; Yan, Aoshuang; Li, Xia; Guo, Xiuhua  (2014). Risk factors for cerebrovascular disease mortality among the elderly in Beijing: a competing risk analysis. PloS one, 9 (2) , e87884More Information

Kirsh, Elliana R; van Leer, Eva; Phero, Heidi J; Xie, Changchun; Khosla, Sid  (2013). Factors associated with singers' perceptions of choral singing well-being. Journal of voice : official journal of the Voice Foundation, 27 (6) , 786.e25-32More Information

Anand, Sonia S; Meyre, David; Pare, Guillaume; Bailey, Swneke D; Xie, Changchun; Zhang, Xiaohe; Montpetit, Alexandre; Desai, Dipika; Bosch, Jackie; Mohan, Viswanathan; Diaz, Rafael; McQueen, Matthew J; Cordell, Heather J; Keavney, Bernard; Yusuf, Salim; Gaudet, Daniel; Gerstein, Hertzel; Engert, James C  (2013). Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study. Diabetes care, 36 (9) , 2836-42More Information

Xie, Changchun; Chen, Ding-Geng  (2013). Letter to the editor. Biometrical journal. Biometrische Zeitschrift, 55 (2) , 264-5More Information

Yamanaka, Osamu; Yuan, Yong; Coulson-Thomas, Vivien Jane; Gesteira, Tarsis Ferreira; Call, Mindy K; Zhang, Yujin; Zhang, Jianhua; Chang, Shao-Hsuan; Xie, Changchun; Liu, Chia-Yang; Saika, Shizuya; Jester, James V; Kao, Winston W-Y  (2013). Lumican binds ALK5 to promote epithelium wound healing. PloS one, 8 (12) , e82730More Information

Zbuk, Kevin; Xie, Changchun; Young, Robin; Heydarpour, Mahyar; Pare, Guillaume; Davis, A Darlene; Miller, Ruby; Lanktree, Matthew B; Saleheen, Danish; Danesh, John; Yusuf, Salim; Engert, James C; Hegele, Robert A; Anand, Sonia S  (2012). BRCA2 variants and cardiovascular disease in a multi-ethnic study. BMC medical genetics, 13, 56More Information

Natarajan, Madhu K; Strauss, Bradley H; Rokoss, Michael; Buller, Christopher E; Mancini, G B John; Xie, Changchun; Sheth, Tej N; Goodhart, David; Cohen, Eric A; Seidelin, Peter; Harper, William; Gerstein, Hertzel CRandomized trial of insulin versus usual care in reducing restenosis after coronary intervention in patients with diabetes. the STent Restenosis And Metabolism (STREAM) study. Cardiovascular revascularization medicine : including molecular interventions, 13 (2) , 95-100More Information

Xie, Changchun  (2012). Weighted multiple testing correction for correlated tests. Statistics in medicine, 31 (4) , 341-52More Information

Do, Ron; Xie, Changchun; Zhang, Xiaohe; Männistö, Satu; Harald, Kennet; Islam, Shofiqul; Bailey, Swneke D; Rangarajan, Sumathy; McQueen, Matthew J; Diaz, Rafael; Lisheng, Liu; Wang, Xingyu; Silander, Kaisa; Peltonen, Leena; Yusuf, Salim; Salomaa, Veikko; Engert, James C; Anand, Sonia S  (2011). The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study. PLoS medicine, 8 (10) , e1001106More Information

Mercuri, Mathew; Mehta, Shamir; Xie, Changchun; Valettas, Nicholas; Velianou, James L; Natarajan, Madhu K  (2011). Radial artery access as a predictor of increased radiation exposure during a diagnostic cardiac catheterization procedure. JACC. Cardiovascular interventions, 4 (3) , 347-52More Information

Chow, Clara K; Islam, Shofiqul; Bautista, Leonelo; Rumboldt, Zvonko; Yusufali, Afzal; Xie, Changchun; Anand, Sonia S; Engert, James C; Rangarajan, Sumathy; Yusuf, Salim  (2011). Parental history and myocardial infarction risk across the world: the INTERHEART Study. Journal of the American College of Cardiology, 57 (5) , 619-27More Information

Assimes, Themistocles L; Hólm, Hilma; Kathiresan, Sekar; Reilly, Muredach P; Thorleifsson, Gudmar; Voight, Benjamin F; Erdmann, Jeanette; Willenborg, Christina; Vaidya, Dhananjay; Xie, Changchun; Patterson, Chris C; Morgan, Thomas M; Burnett, Mary Susan; Li, Mingyao; Hlatky, Mark A; Knowles, Joshua W; Thompson, John R; Absher, Devin; Iribarren, Carlos; Go, Alan; Fortmann, Stephen P; Sidney, Stephen; Risch, Neil; Tang, Hua; Myers, Richard M; Berger, Klaus; Stoll, Monika; Shah, Svati H; Thorgeirsson, Gudmundur; Andersen, Karl; Havulinna, Aki S; Herrera, J Enrique; Faraday, Nauder; Kim, Yoonhee; Kral, Brian G; Mathias, Rasika A; Ruczinski, Ingo; Suktitipat, Bhoom; Wilson, Alexander F; Yanek, Lisa R; Becker, Lewis C; Linsel-Nitschke, Patrick; Lieb, Wolfgang; König, Inke R; Hengstenberg, Christian; Fischer, Marcus; Stark, Klaus; Reinhard, Wibke; Winogradow, Janina; Grassl, Martina; Grosshennig, Anika; Preuss, Michael; Schreiber, Stefan; Wichmann, H-Erich; Meisinger, Christa; Yee, Jean; Friedlander, Yechiel; Do, Ron; Meigs, James B; Williams, Gordon; Nathan, David M; MacRae, Calum A; Qu, Liming; Wilensky, Robert L; Matthai, William H; Qasim, Atif N; Hakonarson, Hakon; Pichard, Augusto D; Kent, Kenneth M; Satler, Lowell; Lindsay, Joseph M; Waksman, Ron; Knouff, Christopher W; Waterworth, Dawn M; Walker, Max C; Mooser, Vincent E; Marrugat, Jaume; Lucas, Gavin; Subirana, Isaac; Sala, Joan; Ramos, Rafael; Martinelli, Nicola; Olivieri, Oliviero; Trabetti, Elisabetta; Malerba, Giovanni; Pignatti, Pier Franco; Guiducci, Candace; Mirel, Daniel; Parkin, Melissa; Hirschhorn, Joel N; Asselta, Rosanna; Duga, Stefano; Musunuru, Kiran; Daly, Mark J; Purcell, Shaun; Eifert, Sandra; Braund, Peter S; Wright, Benjamin J; Balmforth, Anthony J; Ball, Stephen G ; Ouwehand, Willem H; Deloukas, Panos; Scholz, Michael; Cambien, Francois; Huge, Andreas; Scheffold, Thomas; Salomaa, Veikko; Girelli, Domenico; Granger, Christopher B; Peltonen, Leena; McKeown, Pascal P; Altshuler, David; Melander, Olle; Devaney, Joseph M; Epstein, Stephen E; Rader, Daniel J; Elosua, Roberto; Engert, James C; Anand, Sonia S; Hall, Alistair S; Ziegler, Andreas; O'Donnell, Christopher J; Spertus, John A; Siscovick, David; Schwartz, Stephen M; Becker, Diane; Thorsteinsdottir, Unnur; Stefansson, Kari; Schunkert, Heribert; Samani, Nilesh J; Quertermous, Thomas  (2010). Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology, 56 (19) , 1552-63More Information

Bailey, Swneke D; Xie, Changchun; Do, Ron; Montpetit, Alexandre; Diaz, Rafael; Mohan, Viswanathan; Keavney, Bernard; Yusuf, Salim; Gerstein, Hertzel C; Engert, James C; Anand, Sonia  (2010). Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. Diabetes care, 33 (10) , 2250-3More Information

Mercuri, Mathew; Xie, Changchun; Levy, Michael; Valettas, Nicholas; Natarajan, Madhu K  (2009). Predictors of increased radiation dose during percutaneous coronary intervention. The American journal of cardiology, 104 (9) , 1241-4More Information

Mercuri, Mat; Natarajan, Madhu K; Holder, Douglas H; Xie, Changchun; Gafni, Amiram  (2009). Insight into capacity planning for cardiac catheterization services: policy lessons learned from "Looking in the Mirror" over a decade. Health policy (Amsterdam, Netherlands), 91 (3) , 314-20More Information

, ; Kathiresan, Sekar; Voight, Benjamin F; Purcell, Shaun; Musunuru, Kiran; Ardissino, Diego; Mannucci, Pier M; Anand, Sonia; Engert, James C; Samani, Nilesh J; Schunkert, Heribert; Erdmann, Jeanette; Reilly, Muredach P; Rader, Daniel J; Morgan, Thomas; Spertus, John A; Stoll, Monika; Girelli, Domenico; McKeown, Pascal P; Patterson, Chris C; Siscovick, David S; O'Donnell, Christopher J; Elosua, Roberto; Peltonen, Leena; Salomaa, Veikko; Schwartz, Stephen M; Melander, Olle; Altshuler, David; Ardissino, Diego; Merlini, Pier Angelica; Berzuini, Carlo; Bernardinelli, Luisa; Peyvandi, Flora; Tubaro, Marco; Celli, Patrizia; Ferrario, Maurizio; Fetiveau, Raffaela; Marziliano, Nicola; Casari, Giorgio; Galli, Michele; Ribichini, Flavio; Rossi, Marco; Bernardi, Francesco; Zonzin, Pietro; Piazza, Alberto; Mannucci, Pier M; Schwartz, Stephen M; Siscovick, David S; Yee, Jean; Friedlander, Yechiel; Elosua, Roberto; Marrugat, Jaume; Lucas, Gavin; Subirana, Isaac; Sala, Joan; Ramos, Rafael; Kathiresan, Sekar; Meigs, James B; Williams, Gordon; Nathan, David M; MacRae, Calum A; O'Donnell, Christopher J; Salomaa, Veikko; Havulinna, Aki S; Peltonen, Leena; Melander, Olle; Berglund, Goran; Voight, Benjamin F; Kathiresan, Sekar; Hirschhorn, Joel N; Asselta, Rosanna; Duga, Stefano; Spreafico, Marta; Musunuru, Kiran; Daly, Mark J; Purcell, Shaun; Voight, Benjamin F; Purcell, Shaun; Nemesh, James; Korn, Joshua M; McCarroll, Steven A; Schwartz, Stephen M; Yee, Jean; Kathiresan, Sekar; Lucas, Gavin; Subirana, Isaac; Elosua, Roberto; Surti, Aarti; Guiducci, Candace; Gianniny, Lauren; Mirel, Daniel; Parkin, Melissa; Burtt, Noel; Gabriel, Stacey B; Samani, Nilesh J; Thompson, John R; Braund, Peter S; Wright, Benjamin J; Balmforth, Anthony J; Ball, Stephen G; Hall, Alistair S ; Schunkert, Heribert; Erdmann, Jeanette; Linsel-Nitschke, Patrick; Lieb, Wolfgang; Ziegler, Andreas; König, Inke; Hengstenberg, Christian; Fischer, Marcus; Stark, Klaus; Grosshennig, Anika; Preuss, Michael; Wichmann, H-Erich; Schreiber, Stefan; Schunkert, Heribert; Samani, Nilesh J; Erdmann, Jeanette; Ouwehand, Willem; Hengstenberg, Christian; Deloukas, Panos; Scholz, Michael; Cambien, Francois; Reilly, Muredach P; Li, Mingyao; Chen, Zhen; Wilensky, Robert; Matthai, William; Qasim, Atif; Hakonarson, Hakon H; Devaney, Joe; Burnett, Mary-Susan; Pichard, Augusto D; Kent, Kenneth M; Satler, Lowell; Lindsay, Joseph M; Waksman, Ron; Knouff, Christopher W; Waterworth, Dawn M; Walker, Max C; Mooser, Vincent; Epstein, Stephen E; Rader, Daniel J; Scheffold, Thomas; Berger, Klaus; Stoll, Monika; Huge, Andreas; Girelli, Domenico; Martinelli, Nicola; Olivieri, Oliviero; Corrocher, Roberto; Morgan, Thomas; Spertus, John A; McKeown, Pascal; Patterson, Chris C; Schunkert, Heribert; Erdmann, Erdmann; Linsel-Nitschke, Patrick; Lieb, Wolfgang; Ziegler, Andreas; König, Inke R; Hengstenberg, Christian; Fischer, Marcus; Stark, Klaus; Grosshennig, Anika; Preuss, Michael; Wichmann, H-Erich; Schreiber, Stefan; Hólm, Hilma; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Stefansson, Kari; Engert, James C; Do, Ron; Xie, Changchun; Anand, Sonia; Kathiresan, Sekar; Ardissino, Diego; Mannucci, Pier M; Siscovick, David; O'Donnell, Christopher J; Samani, Nilesh J; Melander, Olle; Elosua, Roberto; Peltonen, Leena; Salomaa, Veikko; Schwartz, Stephen M; Altshuler, David  (2009). Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nature genetics, 41 (3) , 334-41More Information

Anand, Sonia S; Xie, Changchun; Paré, Guillaume; Montpetit, Alexandre; Rangarajan, Sumathy; McQueen, Matthew J; Cordell, Heather J; Keavney, Bernard; Yusuf, Salim; Hudson, Thomas J; Engert, James C  (2009). Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study. Circulation. Cardiovascular genetics, 2 (1) , 16-25More Information

de Koning, Lawrence; Merchant, Anwar T; Hegele, Robert A; Xie, Changchun; Vuksan, Vlad; Teo, Koon; Yusuf, Salim; Anand, Sonia S  (2008). Association of the FABP2 T54 variant with plasma triglycerides and insulin resistance in a multiethnic population. Clinical chemistry, 54 (10) , 1742-4More Information

Xavier, Denis; Pais, Prem; Devereaux, P J; Xie, Changchun; Prabhakaran, D; Reddy, K Srinath; Gupta, Rajeev; Joshi, Prashant; Kerkar, Prafulla; Thanikachalam, S; Haridas, K K; Jaison, T M; Naik, Sudhir; Maity, A K; Yusuf, Salim  (2008). Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data. Lancet, 371 (9622) , 1435-42More Information

Anand, Sonia S; Davis, A Darlene; Ahmed, Rashid; Jacobs, Ruby; Xie, Changchun; Hill, Amber; Sowden, Joon; Atkinson, Stephanie; Blimkie, Cameron; Brouwers, Melissa; Morrison, Katherine; de Koning, Larry; Gerstein, Hertzel; Yusuf, Salim A family-based intervention to promote healthy lifestyles in an aboriginal community in Canada. Canadian journal of public health = Revue canadienne de santé publique, 98 (6) , 447-52

, ; Anand, Sonia; Yusuf, Salim; Xie, Changchun; Pogue, Janice; Eikelboom, John; Budaj, Andrzej; Sussex, Bruce; Liu, Lisheng; Guzman, Randy; Cina, Claudio; Crowell, Richard; Keltai, Matyas; Gosselin, Gilbert  (2007). Oral anticoagulant and antiplatelet therapy and peripheral arterial disease. The New England journal of medicine, 357 (3) , 217-27More Information

Eikelboom, John W; Mehta, Shamir R; Anand, Sonia S; Xie, Changchun; Fox, Keith A A; Yusuf, Salim  (2006). Adverse impact of bleeding on prognosis in patients with acute coronary syndromes. Circulation, 114 (8) , 774-82More Information

Schwalm, Jon-David Reid; Ahmad, Mayraj; Velianou, James L; Xie, Changchun; Natarajan, Madhu K  (2006). Primary and rescue percutaneous coronary intervention with paclitaxel-eluting stent implantation in ST-elevation myocardial infarction. The American journal of cardiology, 97 (9) , 1308-10More Information

Mehta, Shamir R; Yusuf, Salim; Díaz, Rafael; Zhu, Jun; Pais, Prem; Xavier, Denis; Paolasso, Ernesto; Ahmed, Rashid; Xie, Changchun; Kazmi, Khawar; Tai, Javed; Orlandini, Andrés; Pogue, Janice; Liu, Lisheng  (2005). Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. JAMA, 293 (4) , 437-46More Information

Yusuf, Salim; Mehta, Shamir R; Xie, Changchun; Ahmed, Rashid J; Xavier, Denis; Pais, Prem; Zhu, Jun; Liu, Lisheng  (2005). Effects of reviparin, a low-molecular-weight heparin, on mortality, reinfarction, and strokes in patients with acute myocardial infarction presenting with ST-segment elevation. JAMA, 293 (4) , 427-35More Information

Yusuf, Salim; Mehta, Shamir R; Díaz, Rafael; Paolasso, Ernesto; Pais, Prem; Xavier, Denis; Xie, Changchun; Ahmed, Rashid J; Khazmi, Khawar; Zhu, Jun; Liu, Lisheng  (2004). Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: the CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction. American heart journal, 148 (6) , 1068-78More Information

Lindsley, Andrew W; Saal, Howard M; Burrow, Thomas A; Hopkin, Robert J; Shchelochkov, Oleg; Khandelwal, Pooja; Xie, Changchun; Bleesing, Jack; Filipovich, Lisa; Risma, Kimberly; Assa'ad, Amal H; Roehrs, Phillip A; Bernstein, Jonathan A  (2016). Defects of B-cell terminal differentiation in patients with type-1 Kabuki syndrome. The Journal of allergy and clinical immunology, 137 (1) , 179-187.e10More Information

Wang, Ke-Sheng; Zuo, Lingjun; Pan, Yue; Xie, Changchun; Luo, Xingguang  (2015). Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations. Journal of psychiatric research, 71, 1-7More Information

Chen, Aimin; Xu, Fan; Xie, Changchun; Wu, Tianying; Vuong, Ann M; Miao, Maohua; Yuan, Wei; DeFranco, Emily A  (2015). Gestational Weight Gain Trend and Population Attributable Risks of Adverse Fetal Growth Outcomes in Ohio. Paediatric and perinatal epidemiology, 29 (4) , 346-50More Information

Li, Yue; Xie, Changchun; Murphy, Susan K; Skaar, David; Nye, Monica; Vidal, Adriana C; Cecil, Kim M; Dietrich, Kim N; Puga, Alvaro; Jirtle, Randy L; Hoyo, Cathrine  (2015). Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environmental health perspectivesMore Information

Kim, Stephani; Xu, Xijin; Zhang, Yuling; Zheng, Xiangbin; Liu, Rongju; Dietrich, Kim; Reponen, Tiina; Ho, Shuk-Mei; Xie, Changchun; Sucharew, Heidi; Huo, Xia; Chen, Aimin  (2018). Metal concentrations in pregnant women and neonates from informal electronic waste recycling. Journal of exposure science & environmental epidemiologyMore Information

Vuong, Ann M; Braun, Joseph M; Yolton, Kimberly; Wang, Zhiyang; Xie, Changchun; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2018). Prenatal and childhood exposure to perfluoroalkyl substances (PFAS) and measures of attention, impulse control, and visual spatial abilities. Environment international, 119, 413-420More Information

Vuong, Ann M; Yolton, Kimberly; Wang, Zhiyang; Xie, Changchun; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2018). Childhood perfluoroalkyl substance exposure and executive function in children at 8?years. Environment international, 119, 212-219More Information

Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Ye, Xiaoyun; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin  (2018). Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8years. Environment international, 111, 224-231More Information

Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M  (2018). Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics, 141 (2) More Information

DeFoor, W Robert; Inge, Thomas H; Jenkins, Todd M; Jackson, Elizabeth; Courcoulas, Anita; Michalsky, Marc; Brandt, Mary; Kollar, Linda; Xie, Changchun  (2018). Prospective evaluation of urinary incontinence in severely obese adolescents presenting for weight loss surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 14 (2) , 214-218More Information

Leung, Yuet-Kin; Ouyang, Bin; Niu, Liang; Xie, Changchun; Ying, Jun; Medvedovic, Mario; Chen, Aimin; Weihe, Pal; Valvi, Damaskini; Grandjean, Philippe; Ho, Shuk-Mei  (2018). Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics, 13 (3) , 290-300More Information

Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2018). Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study. International journal of hygiene and environmental health, 221 (1) , 87-94More Information

Karim, Nagla Abdel; Schuster, James; Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Xie, Changchun; Morris, John C  (2018). Pulmonary sarcomatoid carcinoma: University of Cincinnati experience. Oncotarget, 9 (3) , 4102-4108More Information

Gautam, Yadu; Altaye, Mekibib; Xie, Changchun; Mersha, Tesfaye B  (2017). AdmixPower: Statistical Power and Sample Size Estimation for Mapping Genetic Loci in Admixed Populations. Genetics, 207 (3) , 873-882More Information

Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2017). Prenatal and postnatal polybrominated diphenyl ether (PBDE) exposure and measures of inattention and impulsivity in children. Neurotoxicology and teratology, 64, 20-28More Information

Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Braun, Joseph M; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2017). Childhood polybrominated diphenyl ether (PBDE) exposure and neurobehavior in children at 8 years. Environmental research, 158, 677-684More Information

Wang, Ke-Sheng; Liu, Xuefeng; Ategbole, Muyiwa; Xie, Xin; Liu, Ying; Xu, Chun; Xie, Changchun; Sha, Zhanxin  (2017). Generalized Linear Mixed Model Analysis of Urban-Rural Differences in Social and Behavioral Factors for Colorectal Cancer Screening. Asian Pacific journal of cancer prevention : APJCP, 18 (9) , 2581-2589More Information

Herrick, Robert L; Buckholz, Jeanette; Biro, Frank M; Calafat, Antonia M; Ye, Xiaoyun; Xie, Changchun; Pinney, Susan M  (2017). Polyfluoroalkyl substance exposure in the Mid-Ohio River Valley, 1991-2012. Environmental pollution (Barking, Essex : 1987), 228, 50-60More Information

Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Sjödin, Andreas; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin  (2017). Erratum: "Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children". Environmental health perspectives, 125 (6) , 069001More Information

Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M; Sjödin, Andreas; Calafat, Antonia M; Dietrich, Kim N; Xu, Yingying; Xie, Changchun; Braun, Joseph M; Lanphear, Bruce P; Chen, Aimin  (2017). Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children. Environmental health perspectives, 125 (4) , 746-752More Information

Vuong, Ann M; Braun, Joseph M; Yolton, Kimberly; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Dietrich, Kim N; Lanphear, Bruce P; Chen, Aimin  (2017). Prenatal and postnatal polybrominated diphenyl ether exposure and visual spatial abilities in children. Environmental research, 153, 83-92More Information

Martin, Andrew T; Pinney, Susan M; Xie, Changchun; Herrick, Robert L; Bai, Yun; Buckholz, Jeanette; Martin, Vincent T  (2017). Headache Disorders May Be a Risk Factor for the Development of New Onset Hypothyroidism. Headache, 57 (1) , 21-30More Information

Owusu, Daniel; Pan, Yue; Xie, Changchun; Harirforoosh, Sam; Wang, Ke-Sheng  (2017). Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. Journal of psychiatric research, 84, 27-34More Information

Agarwal, Rishi; Sendilnathan, Arun; Siddiqi, Nabeela Iffat; Gulati, Shuchi; Ghose, Abhimanyu; Xie, Changchun; Olowokure, Olugbenga Olanrele  (2016). Advanced biliary tract cancer: clinical outcomes with ABC-02 regimen and analysis of prognostic factors in a tertiary care center in the United States. Journal of gastrointestinal oncology, 7 (6) , 996-1003More Information

Wang, Ke-Sheng; Liu, Xuefeng; Xie, Changchun; Liu, Ying; Xu, Chun  (2016). Non-parametric Survival Analysis of EPG5 Gene with Age at Onset of Alzheimer's Disease. Journal of molecular neuroscience : MN, 60 (4) , 436-444More Information

Agarwal, Sunil; Mark, Jonathan; Xie, Changchun; Ghulam, Enas; Patil, Yash  (2016). Survival and Prognosis for Malignant Tumors of Odontogenic Origin. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 155 (1) , 113-6More Information

Wang, Ke-Sheng; Owusu, Daniel; Pan, Yue; Xie, Changchun  (2016). Bayesian logistic regression in detection of gene-steroid interaction for cancer at PDLIM5 locus. Journal of genetics, 95 (2) , 331-40

Rebholz, Sandra L; Jones, Thomas; Herrick, Robert L; Xie, Changchun; Calafat, Antonia M; Pinney, Susan M; Woollett, Laura AHypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice. Toxicology reports, 3, 46-54More Information

Xie, Changchun  (2015). Resveratrol does not reduce CVD risk, prolong life - A statistical point of view. Contemporary clinical trials communications, 1, 1More Information

Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin  (2022). Maternal urinary organophosphate ester metabolite concentrations and glucose tolerance during pregnancy: The HOME Study. International journal of hygiene and environmental health, 245, 114026More Information

Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Werner, Erika; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin  (2022). Maternal urinary OPE metabolite concentrations and blood pressure during pregnancy: The HOME study. Environmental research, 207, 112220More Information

Wang, Kesheng; Xu, Chun; Smith, Amanda; Xiao, Danqing; Navia, R Osvaldo; Lu, Yongke; Xie, Changchun; Piamjariyakul, Ubolrat  (2021). Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Progress in neuro-psychopharmacology & biological psychiatry, 111, 110393More Information

Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Dietrich, Kim N; Braun, Joseph M; Webster, Glenys M; Calafat, Antonia M; Lanphear, Bruce P; Chen, Aimin  (2021). Childhood exposure to per- and polyfluoroalkyl substances (PFAS) and neurobehavioral domains in children at age 8 years. Neurotoxicology and teratology, 88, 107022More Information

Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Hoofnagle, Andy; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Yolton, Kimberly; Chen, Aimin  (2021). Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones. American journal of epidemiology, 190 (9) , 1793-1802More Information

Derderian, S Christopher; Dewberry, Lindel C; Patten, Luke; Sitzman, Thomas J; Kaizer, Alexander M; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Mitchell, James E; Inge, Thomas  (2020). Excess skin problems among adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 (8) , 993-998More Information

Yang, Weili; Vuong, Ann M; Xie, Changchun; Dietrich, Kim N; Karagas, Margaret R; Lanphear, Bruce P; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin  (2020). Maternal cadmium exposure and neurobehavior in children: The HOME study. Environmental research, 186, 109583More Information

Ryder, Justin R; Xu, Peixin; Inge, Thomas H; Xie, Changchun; Jenkins, Todd M; Hur, Chin; Lee, Minyi; Choi, Jin; Michalsky, Marc P; Kelly, Aaron S; Urbina, Elaine M  (2020). Thirty-Year Risk of Cardiovascular Disease Events in Adolescents with Severe Obesity. Obesity (Silver Spring, Md.), 28 (3) , 616-623More Information

Abdel Karim, Nagla; Khaddasn, Sinan; Shehata, Mahmoud; Mostafa, Ahmed; Magdy, Mohamed; Eldessouki, Ihab; Xie, Changchun; Benzequene, Sadia  (2020). Stenting in Non-Small Cell Lung Cancer: How Does It Affect the Outcomes?. Asian Pacific journal of cancer prevention : APJCP, 21 (1) , 175-178More Information

Bjornstad, Petter; Hughan, Kara; Kelsey, Megan M; Shah, Amy S; Lynch, Jane; Nehus, Edward; Mitsnefes, Mark; Jenkins, Todd; Xu, Peixin; Xie, Changchun; Inge, Thomas; Nadeau, Kristen  (2020). Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes. Diabetes care, 43 (1) , 187-195More Information

Percy, Zana; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Lanphear, Bruce P; Yolton, Kimberly; Vuong, Ann M; Cecil, Kim M; Braun, Joseph M; Xie, Changchun; Chen, Aimin  (2020). Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out. Chemosphere, 239, 124701More Information

Fassler, Cecily S; Gutmark-Little, Iris; Xie, Changchun; Giannini, Courtney M; Chandler, Donald W; Biro, Frank M; Pinney, Susan M  (2019). Sex Hormone Phenotypes in Young Girls and the Age at Pubertal Milestones. The Journal of clinical endocrinology and metabolism, 104 (12) , 6079-6089More Information

Xie, Changchun; Leung, Yuet-Kin; Chen, Aimin; Long, Ding-Xin; Hoyo, Catherine; Ho, Shuk-Mei  (2019). Differential methylation values in differential methylation analysis. Bioinformatics (Oxford, England), 35 (7) , 1094-1097More Information

An, Yu; Fnu, Gulimirerouzi; Xie, Changchun; Weber, Georg F  (2023). Meta-analysis of Osteopontin splice variants in cancer. BMC cancer, 23 (1) , 373More Information

Lewis, Clayton S; Bari, Khurram; Xie, Changchun; Sherman, Kenneth E; Vasse, Marc; Van Dreden, Patrick; Bogdanov, Vladimir Y  (2023). Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease. BMC gastroenterology, 23 (1) , 65More Information

Connelly, Katherine M; Winslow, Stephanie E; Smith, Justin; Ahmad, Saad S; Xie, Changchun; Hinckley, William R; Gottula, Adam L; Lane, Bennett H  (2023). Management of patients with impella devices or intra-aortic balloon pumps during helicopter air ambulance transport in observational data. Perfusion, 2676591231158273More Information

Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin  (2023). Gestational exposure to organophosphate esters and infant anthropometric measures in the first 4 weeks after birth. The Science of the total environment, 857 (Pt 1) , 159322More Information

Wang, Kesheng; Shafique, Saima; Xiao, Danqing; Walter, Suzy Mascaro; Liu, Ying; Piamjariyakul, Ubolrat; Xie, Changchun  (2023). Repeated measures analysis of opioid use disorder treatment on clinical opiate withdrawal scale in a randomized clinical trial: sex differences. Journal of addictive diseases, 1-12More Information

Yang, Weili; Braun, Joseph M; Vuong, Ann M; Percy, Zana; Xu, Yingying; Xie, Changchun; Deka, Ranjan; Calafat, Antonia M; Ospina, Maria; Burris, Heather H; Yolton, Kimberly; Cecil, Kim M; Lanphear, Bruce P; Chen, Aimin  (2023). Associations of gestational exposure to organophosphate esters with gestational age and neonatal anthropometric measures: The HOME study. Environmental pollution (Barking, Essex : 1987), 316 (Pt 1) , 120516More Information

Wang, Kesheng; Xu, Chun; Theeke, Laurie A; Xiao, Danqing; Luo, Xingguang; Xie, Changchun Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer's Disease. Nursing research, 72 (1) , 66-73More Information

Wang, Kesheng; DiChiacchio, Toni; Fang, Wei; Lander, Laura; Feinberg, Judith; Xie, Changchun; Winstanley, Erin L; Ubolrat Piamjariyakul,  (2022). Longitudinal study of impact of medication for opioid use disorder on Hamilton Depression Rating Scale. Journal of affective disorders, 297, 148-155More Information

Percy, Zana; Vuong, Ann M; Xu, Yingying; Xie, Changchun; Ospina, Maria; Calafat, Antonia M; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Dietrich, Kim N; Chen, Aimin; Yolton, Kimberly  (2021). Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study. Neurotoxicology, 87, 149-155More Information

Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M  (2021). Air pollution and the pandemic: Long-term PM2.5 exposure and disease severity in COVID-19 patients. Respirology (Carlton, Vic.), 26 (12) , 1181-1187More Information

Xu, Zongli; Xie, Changchun; Taylor, Jack A; Niu, Liang  (2021). ipDMR: identification of differentially methylated regions with interval P-values. Bioinformatics (Oxford, England), 37 (5) , 711-713More Information

Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M  (2021). Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients. Respiratory medicine, 178, 106313More Information

Ryder, Justin R; Xu, Peixin; Nadeau, Kristen J; Kelsey, Megan M; Xie, Changchun; Jenkins, Todd; Inge, Thomas H; Bjornstad, Petter  (2021). Effect of surgical versus medical therapy on estimated cardiovascular event risk among adolescents with type 2 diabetes and severe obesity. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 17 (1) , 23-33More Information

Vuong, Ann M; Xie, Changchun; Jandarov, Roman; Dietrich, Kim N; Zhang, Hongmei; Sjödin, Andreas; Calafat, Antonia M; Lanphear, Bruce P; McCandless, Lawrence; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin  (2020). Prenatal exposure to a mixture of persistent organic pollutants (POPs) and child reading skills at school age. International journal of hygiene and environmental health, 228, 113527More Information

Percy, Zana; Vuong, Ann M; Ospina, Maria; Calafat, Antonia M; La Guardia, Mark J; Xu, Yingying; Hale, Robert C; Dietrich, Kim N; Xie, Changchun; Lanphear, Bruce P; Braun, Joseph M; Cecil, Kim M; Yolton, Kimberly; Chen, Aimin  (2020). Organophosphate esters in a cohort of pregnant women: Variability and predictors of exposure. Environmental research, 184, 109255More Information

Kim, Stephani S; Xu, Xijin; Zhang, Yuling; Zheng, Xiangbin; Liu, Rongju; Dietrich, Kim N; Reponen, Tiina; Xie, Changchun; Sucharew, Heidi; Huo, Xia; Chen, Aimin  (2020). Birth outcomes associated with maternal exposure to metals from informal electronic waste recycling in Guiyu, China. Environment international, 137, 105580More Information

Derderian, S Christopher; Patten, Luke; Kaizer, Alexander M; Inge, Thomas H; Jenkins, Todd M; Michalsky, Marc P; Xie, Changchun; Dewberry, Lindel C; Sitzman, Thomas J  (2020). Body contouring in adolescents after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16 (1) , 137-142More Information

Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P  (2019). Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery. Pediatrics, 144 (6) More Information

Abdel Karim, Nagla Fawzy; Hassan, Rammey; Siddiqi, Nabeela Iffat; Eldessouki, Ihab; Gaber, Ola; Rahouma, Mohamed; Kamel, Mohamed; Yellu, Mhender; Gulati, Shuchi; Xie, Changchun; Magdy, Mohamed; Pruemer, Jane  (2019). Impact of tricyclic antidepressants, selective serotonin reuptake inhibitors, and other antidepressants on overall survival of patients with advanced lung cancer from 2004 to 2014: University of Cincinnati experience. The Journal of international medical research, 47 (12) , 6016-6026More Information

Benoit, Justin L; McMullan, Jason T; Wang, Henry E; Xie, Changchun; Xu, Peixin; Hart, Kimberly W; Stolz, Uwe; Lindsell, Christopher J  (2019). Timing of Advanced Airway Placement after Witnessed Out-of-Hospital Cardiac Arrest. Prehospital emergency care, 23 (6) , 838-846More Information

Fassler, Cecily S; Pinney, Sara E; Xie, Changchun; Biro, Frank M; Pinney, Susan M  (2019). Complex relationships between perfluorooctanoate, body mass index, insulin resistance and serum lipids in young girls. Environmental research, 176, 108558More Information

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A  (2019). Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine, 380 (22) , 2136-2145More Information

Vuong, Ann M; Yolton, Kimberly; Xie, Changchun; Dietrich, Kim N; Braun, Joseph M; Webster, Glenys M; Calafat, Antonia M; Lanphear, Bruce P; Chen, Aimin  (2019). Prenatal and childhood exposure to poly- and perfluoroalkyl substances (PFAS) and cognitive development in children at age 8 years. Environmental research, 172, 242-248More Information

Kharofa, Jordan; Mierzwa, Michelle; Olowokure, Olugbenga; Sussman, Jeffrey; Latif, Tahir; Gupta, Anumeha; Xie, Changchun; Patel, Sameer; Esslinger, Hope; Mcgill, Brian; Wolf, Eric; Ahmad, Syed A  (2019). Pattern of Marginal Local Failure in a Phase II Trial of Neoadjuvant Chemotherapy and Stereotactic Body Radiation Therapy for Resectable and Borderline Resectable Pancreas Cancer. American journal of clinical oncology, 42 (3) , 247-252More Information

Greene, Alexis D; Kendziorski, Jessica A; Buckholz, Jeanette M; Niu, Liang; Xie, Changchun; Pinney, Susan M; Burns, Katherine A  (2019). Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. Reproductive toxicology (Elmsford, N.Y.), 84, 26-31More Information

Vuong, Ann M; Braun, Joseph M; Wang, Zhiyang; Yolton, Kimberly; Xie, Changchun; Sjodin, Andreas; Webster, Glenys M; Lanphear, Bruce P; Chen, Aimin  (2019). Exposure to polybrominated diphenyl ethers (PBDEs) during childhood and adiposity measures at age 8 years. Environment international, 123, 148-155More Information

Liang, Hong; Vuong, Ann M; Xie, Changchun; Webster, Glenys M; Sjödin, Andreas; Yuan, Wei; Miao, Maohua; Braun, Joseph M; Dietrich, Kim N; Yolton, Kimberly; Lanphear, Bruce P; Chen, Aimin  (2019). Childhood polybrominated diphenyl ether (PBDE) serum concentration and reading ability at ages 5 and 8 years: The HOME Study. Environment international, 122, 330-339More Information

Chen, Yao-Long; Yao, Liang; Xiao, Xiao-Juan; Wang, Qi; Wang, Ze-Hao; Liang, Fu-Xiang; Liang, Hui; Wang, Xin; Shen, Xi-Ping; Xie, Chang-Chun; Yang, Ke-Hu  (2012). Quality assessment of clinical guidelines in China: 1993 - 2010. Chinese medical journal, 125 (20) , 3660-4

Academic - Division of Biostatistics and Bioinformatics, Department of Environmental Health, University of Cincinnati
104 Kettering Lab, 160 Panzeca Way
Cincinnati  Ohio, 45267
Phone: (513)-558-0229
xiecn@ucmail.uc.edu