Jagjit Yadav

Jagjit S Yadav , BS, MS, PhD

Professor

Kettering Lab Complex

137

COM EH EGMT Yadav Lab - 0056

Professional Summary

Research Interests:  Dr. Yadav’s research program focuses on respiratory/microbial pathogenesis and immunotoxicology research as related to environmental health. His laboratory is involved in the following major areas of research: 1). Etiology, biomarkers, and mechanisms of environmental and occupational lung diseases and infections using mouse models and clinical specimens; 2). Molecular/cellular signaling events and mechanisms underlying pulmonary toxicity due to chemical and nanoparticle exposures using cellular and animal models. A major focus is to understand the role of host microbiome and genetic background in respiratory toxicity/infection/disease susceptibility using in vivo (rodent) models; 3). Cytochrome P450 research for xenobiotic metabolism/detoxification of environmental carcinogens and toxicants in lower (fungal) and higher (human) eukaryotes. Focus is on P450 genomics, functional deorphanization, structure-activity relationship analysis, and role of P450 genetic polymorphisms in xenobiotic/drug toxicity.

Education

BS: Kurukshetra University India, 1976 (Biological Sciences, Chemistry)

MS: Kurukshetra University (NDRI) India, 1978 (Microbiology)

PhD: Kurukshetra University (NDRI) India, 1984 (Microbiology)

Research Support

Grant: #R01 OH007364 Investigators:Yadav, Jagjit 07-01-2005 -06-30-2010 National Institute for Occupational Safety and Health Mycobacteria in Metalworking Fluids Role:PI $781,381.00 Closed Level:Federal

Investigators:Yadav, Jagjit 10-01-2003 -12-31-2005 Other Federal Project Three Role:PI $264,682.00 Closed Level:Federal

Investigators:Yadav, Jagjit 01-01-2005 -12-31-2006 United Auto Works-Delphi Microbial Contaminants in Metalworking Fluids Role:PI $599,948.00 Closed Level:Other

Grant: #5-U56-AI-57164-02-A0-S0-E0 Investigators:Yadav, Jagjit 09-04-2003 -08-31-2006 National Institute of Allergy and Infectious Diseases Genomics for Identification of Biothreat Agents Role:PI $60,000.00 Closed Level:Federal

Grant: #5-R01-ES-10210-03-A0-S0-E0 Investigators:Yadav, Jagjit 02-01-2001 -01-31-2005 National Institute of Environmental Health Sciences Xenobiotic-Oxidizing P450 System in a White Rot Fungus Role:PI $688,500.00 Closed Level:Federal

Grant: #1-R01-OH-07364-03-A1-S0-E0 Investigators:Yadav, Jagjit 09-30-2001 -09-29-2005 National Institute for Occupational Safety and Health Molecular Analysis of Mycobacteria in Cutting Fluids Role:PI $720,920.00 Closed Level:Federal

Grant: #R21 AI070865-01A1 Investigators:Yadav, Jagjit 08-01-2007 -07-31-2011 National Institute of Allergy and Infectious Diseases Genetic Determinants of Host Susceptibility to Pulmonary Anthrax Role:PI $424,554.00

Grant: #R01 ES015543 Investigators:Yadav, Jagjit 08-01-2008 -04-30-2013 National Institute of Environmental Health Sciences Fungal P450 Systems in Biodegradation of Higher PAHS Role:PI $1,064,704.00 Active Level:Federal

Grant: #R01 OH00764 Investigators:Lockey, James; Succop, Paul; Yadav, Jagjit 08-01-2010 -07-31-2015 National Institute for Occupational Safety and Health MWF Mycobacteria Antigens in Occupational Hypersensitivity Pneumonitis Role:PI $1,534,422.00 Active Level:Federal

Grant: #T4-010-ASU Investigators:Yadav, Jagjit 01-01-2011 -12-31-2011 BP Chemicals, Incorporated Marine Environmental Sciences Consortium Role:PI $10,000.00 Closed Level:Industry

Grant: #P30ES006096 Investigators:Caruso, Joseph; Chen, Aimin; Deka, Ranjan; Greis, Kenneth; Haynes, Erin; Ho, Shuk Mei; Lemasters, Grace; Leung, Yuet Kin; Medvedovic, Mario; Meller, Jaroslaw; Meloncon, Lisa; Pinney, Susan; Porollo, Alexey; Puga, Alvaro; Thomas, Michael; Woo, Daniel; Yadav, Jagjit; Yancey, Elissa 04-01-2013 -03-31-2018 National Institute of Environmental Health Sciences Environmental Genetics Role:Collaborator $1,743,768.00 Active Level:Federal

Grant: #R21 AI115358 Investigators:Huang, Shouxiong; Yadav, Jagjit 12-01-2014 -11-30-2016 National Institute of Allergy and Infectious Diseases Antigen metabolomics for mucosal-associated invariant T cells in tuberculosis Role:Collaborator $277,011.00 Awarded Level:Federal

Grant: #1 R21OH011826-01-00 Investigators:Yadav, Jagjit 09-30-2020 -09-29-2022 Centers for Disease Control and Prevention Circulating Cell-free Antigens for Monitoring of Machining Fluids Role:PI $214,998.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Johansson, Elisabet; Boivin, Gregory P; Yadav, Jagjit S (2017. ) Early immunopathological events in acute model of mycobacterial hypersensitivity pneumonitis in mice.Journal of immunotoxicology, , 14 (1 ) ,77-88 More Information

Frank, Evan A; Carreira, Vinicius S; Shanmukhappa, Kumar; Medvedovic, Mario; Prows, Daniel R; Yadav, Jagjit S (2017. ) Genetic susceptibility to toxicologic lung responses among inbred mouse strains following exposure to carbon nanotubes and profiling of underlying gene networks.Toxicology and applied pharmacology, , 327 ,59-70 More Information

Davis, Shannon C; Yadav, Jagjit S; Barrow, Stephanie D; Robertson, Boakai K (2017. ) Gut microbiome diversity influenced more by the Westernized dietary regime than the body mass index as assessed using effect size statistic.MicrobiologyOpen, , More Information

Mgbeahuruike, Anthony C; Kovalchuk, Andriy; Ubhayasekera, Wimal; Nelson, David R; Yadav, Jagjit S (2017. ) CYPome of the conifer pathogen Heterobasidion irregulare: Inventory, phylogeny, and transcriptional analysis of the response to biocontrol.Fungal biology, , 121 (2 ) ,158-171 More Information

Bhattacharya, Sukanta S; Yadav, Jagjit S (2016. ) Microbial P450 enzymes in bioremediation and drug discovery: Emerging potentials and challenges. Current protein & peptide science, ,

Chandra, Harish; Yadav, Jagjit S (2016. ) Human leukocyte antigen (HLA)-binding epitopes dataset for the newly identified T-cell antigens of Mycobacterium immunogenum.Data in brief, , 8 ,1069-71 More Information

Chandra, Harish; Yadav, Jagjit S (2016. ) T-cell antigens of Mycobacterium immunogenum, an etiological agent of occupational hypersensitivity pneumonitis.Molecular immunology, , 75 ,168-77 More Information

Corrochano, Luis M; Kuo, Alan; Marcet-Houben, Marina; Polaino, Silvia; Salamov, Asaf; Villalobos-Escobedo, José M; Grimwood, Jane; Álvarez, M Isabel; Avalos, Javier; Bauer, Diane; Benito, Ernesto P; Benoit, Isabelle; Burger, Gertraud; Camino, Lola P; Cánovas, David; Cerdá-Olmedo, Enrique; Cheng, Jan-Fang; Domínguez, Angel; Eliáš, Marek; Eslava, Arturo P; Glaser, Fabian; Gutiérrez, Gabriel; Heitman, Joseph; Henrissat, Bernard; Iturriaga, Enrique A; Lang, B Franz; Lavín, José L; Lee, Soo Chan; Li, Wenjun; Lindquist, Erika; López-García, Sergio; Luque, Eva M; Marcos, Ana T; Martin, Joel; McCluskey, Kevin; Medina, Humberto R; Miralles-Durán, Alejandro; Miyazaki, Atsushi; Muñoz-Torres, Elisa; Oguiza, José A; Ohm, Robin A; Olmedo, María; Orejas, Margarita; Ortiz-Castellanos, Lucila; Pisabarro, Antonio G; Rodríguez-Romero, Julio; Ruiz-Herrera, José; Ruiz-Vázquez, Rosa; Sanz, Catalina; Schackwitz, Wendy; Shahriari, Mahdi; Shelest, Ekaterina; Silva-Franco, Fátima; Soanes, Darren; Syed, Khajamohiddin; Tagua, Víctor G; Talbot, Nicholas J; Thon, Michael R; Tice, Hope; de Vries, Ronald P; Wiebenga, Ad; Yadav, Jagjit S; Braun, Edward L; Baker, Scott E; Garre, Victoriano; Schmutz, Jeremy; Horwitz, Benjamin A; Torres-Martínez, Santiago; Idnurm, Alexander; Herrera-Estrella, Alfredo; Gabaldón, Toni; Grigoriev, Igor V (2016. ) Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication.Current biology : CB, , 26 (12 ) ,1577-84 More Information

Frank, Evan A; Carreira, Vinicius S; Birch, M Eileen; Yadav, Jagjit S (2016. ) Carbon Nanotube and Asbestos Exposures Induce Overlapping but Distinct Profiles of Lung Pathology in Non-Swiss Albino CF-1 Mice.Toxicologic pathology, , 44 (2 ) ,211-25 More Information

Nagy, László G; Riley, Robert; Tritt, Andrew; Adam, Catherine; Daum, Chris; Floudas, Dimitrios; Sun, Hui; Yadav, Jagjit S; Pangilinan, Jasmyn; Larsson, Karl-Henrik; Matsuura, Kenji; Barry, Kerrie; Labutti, Kurt; Kuo, Rita; Ohm, Robin A; Bhattacharya, Sukanta S; Shirouzu, Takashi; Yoshinaga, Yuko; Martin, Francis M; Grigoriev, Igor V; Hibbett, David S (2015. ) Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides Insights into the Origins of Lignocellulose Decay Capabilities.Molecular biology and evolution, , More Information

Frank, Evan A; Birch, M Eileen; Yadav, Jagjit S (2015. ) MyD88 mediates in vivo effector functions of alveolar macrophages in acute lung inflammatory responses to carbon nanotube exposure.Toxicology and applied pharmacology, , 288 (3 ) ,322-9 More Information

Chandra, Harish; Lockey, James; Yadav, Jagjit S (2015. ) Novel antigens of Mycobacterium immunogenum relevant in serodiagnosis of occupational hypersensitivity pneumonitis in machinists.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, , 114 (6 ) ,525-6 More Information

Varughese, Eunice A; Kasper, Susan; Anneken, Emily M; Yadav, Jagjit S (2015. ) SHP-2 Mediates Cryptosporidium parvum Infectivity in Human Intestinal Epithelial Cells.PloS one, , 10 (11 ) ,e0142219 More Information

Varughese, Eunice A; Bennett-Stamper, Christina L; Wymer, Larry J; Yadav, Jagjit S (2014. ) A new in vitro model using small intestinal epithelial cells to enhance infection of Cryptosporidium parvum.Journal of microbiological methods, , 106 ,47-54 More Information

Kapoor, Renuka; Selvaraju, Suresh B; Yadav, Jagjit S (2014. ) Extended tracking of the microbial community structure and dynamics in an industrial synthetic metalworking fluid system.FEMS microbiology ecology, , 87 (3 ) ,664-77 More Information

Robertson, Boakai K; Harden, Carol; Selvaraju, Suresh B; Pradhan, Suman; Yadav, Jagjit S (2014. ) Molecular Detection, Quantification, and Toxigenicity Profiling of Aeromonas spp. in Source- and Drinking-Water.The open microbiology journal, , 8 ,32-9 More Information

Syed, Khajamohiddin; Nelson, David R; Riley, Robert; Yadav, Jagjit S (2013. ) Genomewide annotation and comparative genomics of cytochrome P450 monooxygenases (P450s) in the polypore species Bjerkandera adusta, Ganoderma sp. and Phlebia brevispora.Mycologia, , 105 (6 ) ,1445-55 More Information

Bhattacharya, Sukanta S; Syed, Khajamohiddin; Shann, Jodi; Yadav, Jagjit S (2013. ) A novel P450-initiated biphasic process for sustainable biodegradation of benzo[a]pyrene in soil under nutrient-sufficient conditions by the white rot fungus Phanerochaete chrysosporium.Journal of hazardous materials, , 261 ,675-83 More Information

Syed, Khajamohiddin; Porollo, Aleksey; Miller, David; Yadav, Jagjit S (2013. ) Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons.Protein engineering, design & selection : PEDS, , 26 (9 ) ,553-7 More Information

Syed, Khajamohiddin; Porollo, Aleksey; Lam, Ying Wai; Grimmett, Paul E; Yadav, Jagjit S (2013. ) CYP63A2, a catalytically versatile fungal P450 monooxygenase capable of oxidizing higher-molecular-weight polycyclic aromatic hydrocarbons, alkylphenols, and alkanes.Applied and environmental microbiology, , 79 (8 ) ,2692-702 More Information

Chandra, Harish; Yadav, Ekta; Yadav, Jagjit S (2013. ) Alveolar macrophage innate response to Mycobacterium immunogenum, the etiological agent of hypersensitivity pneumonitis: role of JNK and p38 MAPK pathways.PloS one, , 8 (12 ) ,e83172 More Information

Syed, Khajamohiddin; Yadav, Jagjit S (2012. ) P450 monooxygenases (P450ome) of the model white rot fungus Phanerochaete chrysosporium.Critical reviews in microbiology, , 38 (4 ) ,339-63 More Information

Suzuki, Hitoshi; MacDonald, Jacqueline; Syed, Khajamohiddin; Salamov, Asaf; Hori, Chiaki; Aerts, Andrea; Henrissat, Bernard; Wiebenga, Ad; VanKuyk, Patricia A; Barry, Kerrie; Lindquist, Erika; LaButti, Kurt; Lapidus, Alla; Lucas, Susan; Coutinho, Pedro; Gong, Yunchen; Samejima, Masahiro; Mahadevan, Radhakrishnan; Abou-Zaid, Mamdouh; de Vries, Ronald P; Igarashi, Kiyohiko; Yadav, Jagjit S; Grigoriev, Igor V; Master, Emma R (2012. ) Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P. chrysosporium, to elucidate the genetic basis of the distinct wood types they colonize.BMC genomics, , 13 ,444 More Information

Floudas, Dimitrios; Binder, Manfred; Riley, Robert; Barry, Kerrie; Blanchette, Robert A; Henrissat, Bernard; Martínez, Angel T; Otillar, Robert; Spatafora, Joseph W; Yadav, Jagjit S; Aerts, Andrea; Benoit, Isabelle; Boyd, Alex; Carlson, Alexis; Copeland, Alex; Coutinho, Pedro M; de Vries, Ronald P; Ferreira, Patricia; Findley, Keisha; Foster, Brian; Gaskell, Jill; Glotzer, Dylan; Górecki, Pawe?; Heitman, Joseph; Hesse, Cedar; Hori, Chiaki; Igarashi, Kiyohiko; Jurgens, Joel A; Kallen, Nathan; Kersten, Phil; Kohler, Annegret; Kües, Ursula; Kumar, T K Arun; Kuo, Alan; LaButti, Kurt; Larrondo, Luis F; Lindquist, Erika; Ling, Albee; Lombard, Vincent; Lucas, Susan; Lundell, Taina; Martin, Rachael; McLaughlin, David J; Morgenstern, Ingo; Morin, Emanuelle; Murat, Claude; Nagy, Laszlo G; Nolan, Matt; Ohm, Robin A; Patyshakuliyeva, Aleksandrina; Rokas, Antonis; Ruiz-Dueñas, Francisco J; Sabat, Grzegorz; Salamov, Asaf; Samejima, Masahiro; Schmutz, Jeremy; Slot, Jason C; St John, Franz; Stenlid, Jan; Sun, Hui; Sun, Sheng; Syed, Khajamohiddin; Tsang, Adrian; Wiebenga, Ad; Young, Darcy; Pisabarro, Antonio; Eastwood, Daniel C; Martin, Francis; Cullen, Dan; Grigoriev, Igor V; Hibbett, David S (2012. ) The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.Science (New York, N.Y.), , 336 (6089 ) ,1715-9 More Information

Fernandez-Fueyo, Elena; Ruiz-Dueñas, Francisco J; Ferreira, Patricia; Floudas, Dimitrios; Hibbett, David S; Canessa, Paulo; Larrondo, Luis F; James, Tim Y; Seelenfreund, Daniela; Lobos, Sergio; Polanco, Rubén; Tello, Mario; Honda, Yoichi; Watanabe, Takahito; Watanabe, Takashi; Ryu, Jae San; San, Ryu Jae; Kubicek, Christian P; Schmoll, Monika; Gaskell, Jill; Hammel, Kenneth E; St John, Franz J; Vanden Wymelenberg, Amber; Sabat, Grzegorz; Splinter BonDurant, Sandra; Syed, Khajamohiddin; Yadav, Jagjit S; Doddapaneni, Harshavardhan; Subramanian, Venkataramanan; Lavín, José L; Oguiza, José A; Perez, Gumer; Pisabarro, Antonio G; Ramirez, Lucia; Santoyo, Francisco; Master, Emma; Coutinho, Pedro M; Henrissat, Bernard; Lombard, Vincent; Magnuson, Jon Karl; Kües, Ursula; Hori, Chiaki; Igarashi, Kiyohiko; Samejima, Masahiro; Held, Benjamin W; Barry, Kerrie W; LaButti, Kurt M; Lapidus, Alla; Lindquist, Erika A; Lucas, Susan M; Riley, Robert; Salamov, Asaf A; Hoffmeister, Dirk; Schwenk, Daniel; Hadar, Yitzhak; Yarden, Oded; de Vries, Ronald P; Wiebenga, Ad; Stenlid, Jan; Eastwood, Daniel; Grigoriev, Igor V; Berka, Randy M; Blanchette, Robert A; Kersten, Phil; Martinez, Angel T; Vicuna, Rafael; Cullen, Dan (2012. ) Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis.Proceedings of the National Academy of Sciences of the United States of America, , 109 (14 ) ,5458-63 More Information

Kapoor, Renuka; Yadav, Jagjit S (2012. ) Expanding the mycobacterial diversity of metalworking fluids (MWFs): evidence showing MWF colonization by Mycobacterium abscessus.FEMS microbiology ecology, , 79 (2 ) ,392-9 More Information

Yadav, Jagjit S; Pradhan, Suman; Kapoor, Renuka; Bangar, Hansraj; Burzynski, Benjamin B; Prows, Daniel R; Levin, Linda (2011. ) Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice.Infection and immunity, , 79 (8 ) ,3204-15 More Information

Syed, Khajamohiddin; Kattamuri, Chandramohan; Thompson, Thomas B; Yadav, Jagjit S (2011. ) Cytochrome b? reductase-cytochrome b? as an active P450 redox enzyme system in Phanerochaete chrysosporium: atypical properties and in vivo evidence of electron transfer capability to CYP63A2.Archives of biochemistry and biophysics, , 509 (1 ) ,26-32 More Information

Selvaraju, Suresh B; Khan, Izhar U H; Yadav, Jagjit S (2011. ) Susceptibility of Mycobacterium immunogenum and Pseudomonas fluorescens to formaldehyde and non-formaldehyde biocides in semi-synthetic metalworking fluids.International journal of molecular sciences, , 12 (1 ) ,725-41 More Information

Syed, Khajamohiddin; Porollo, Aleksey; Lam, Ying Wai; Yadav, Jagjit S (2011. ) A fungal P450 (CYP5136A3) capable of oxidizing polycyclic aromatic hydrocarbons and endocrine disrupting alkylphenols: role of Trp(129) and Leu(324).PloS one, , 6 (12 ) ,e28286 More Information

Subramanian, Venkataramanan; Doddapaneni, Harshavardhan; Syed, Khajamohiddin; Yadav, Jagjit S (2010. ) P450 redox enzymes in the white rot fungus Phanerochaete chrysosporium: gene transcription, heterologous expression, and activity analysis on the purified proteins.Current microbiology, , 61 (4 ) ,306-14 More Information

Kapoor, Renuka; Yadav, Jagjit S (2010. ) Development of a rapid ATP bioluminescence assay for biocidal susceptibility testing of rapidly growing mycobacteria.Journal of clinical microbiology, , 48 (10 ) ,3725-8 More Information

Syed, Khajamohiddin; Doddapaneni, Harshavardhan; Subramanian, Venkataramanan; Lam, Ying Wai; Yadav, Jagjit S (2010. ) Genome-to-function characterization of novel fungal P450 monooxygenases oxidizing polycyclic aromatic hydrocarbons (PAHs).Biochemical and biophysical research communications, , 399 (4 ) ,492-7 More Information

Subramanian, Venkataramanan; Yadav, Jagjit S (2009. ) Role of P450 monooxygenases in the degradation of the endocrine-disrupting chemical nonylphenol by the white rot fungus Phanerochaete chrysosporium.Applied and environmental microbiology, , 75 (17 ) ,5570-80 More Information

Gupta, Manish K; Subramanian, Venkataraman; Yadav, Jaglit S (2009. ) Immunoproteomic identification of secretory and subcellular protein antigens and functional evaluation of the secretome fraction of Mycobacterium immunogenum, a newly recognized species of the Mycobacterium chelonae-Mycobacterium abscessus group.Journal of proteome research, , 8 (5 ) ,2319-30 More Information

Kapoor, Renuka; Yadav, Jagjit S (2009. ) Development of a species-specific colorimetric-PCR assay for detection and species differentiation of Mycobacterium immunogenum and Mycobacterium chelonae and its comparison with quantitative real-time PCR for field metalworking fluids.Molecular and cellular probes, , 23 (2 ) ,75-82 More Information

Selvaraju, S B; Khan, I U H; Yadav, J S (2008. ) Specific detection and quantification of culturable and non-culturable mycobacteria in metalworking fluids by fluorescence-based methods.Letters in applied microbiology, , 47 (5 ) ,451-6 More Information

Selvaraju, Suresh B; Kapoor, Renuka; Yadav, Jagjit S (2008. ) Peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) assay for specific detection of Mycobacterium immunogenum and DNA-FISH assay for analysis of pseudomonads in metalworking fluids and sputum.Molecular and cellular probes, , 22 (5-6 ) ,273-80 More Information

Subramanian, Venkataramanan; Yadav, Jagjit S (2008. ) REGULATION AND HETEROLOGOUS EXPRESSION OF P450 ENZYME SYSTEM COMPONENTS OF THE WHITE ROT FUNGUS PHANEROCHAETE CHRYSOSPORIUM.Enzyme and microbial technology, , 43 (2 ) ,205-213 More Information

Selvaraju, Suresh B; Khan, Izhar U H; Yadav, Jagjit S (2008. ) Differential biocide susceptibility of the multiple genotypes of Mycobacterium immunogenum.Journal of industrial microbiology & biotechnology, , 35 (3 ) ,197-203 More Information

Wang, Huiyan; Yadav, Jagjit S (2007. ) Global gene expression changes underlying Stachybotrys chartarum toxin-induced apoptosis in murine alveolar macrophages: evidence of multiple signal transduction pathways.Apoptosis : an international journal on programmed cell death, , 12 (3 ) ,535-48 More Information

Yadav, J S; Doddapaneni, H; Subramanian, V (2006. ) P450ome of the white rot fungus Phanerochaete chrysosporium: structure, evolution and regulation of expression of genomic P450 clusters.Biochemical Society transactions, , 34 (Pt 6 ) ,1165-9 More Information

Wang, Huiyan; Yadav, Jagjit S (2006. ) DNA damage, redox changes, and associated stress-inducible signaling events underlying the apoptosis and cytotoxicity in murine alveolar macrophage cell line MH-S by methanol-extracted Stachybotrys chartarum toxins.Toxicology and applied pharmacology, , 214 (3 ) ,297-308 More Information

Doddapaneni, H; Yadav, J S (2005. ) Microarray-based global differential expression profiling of P450 monooxygenases and regulatory proteins for signal transduction pathways in the white rot fungus Phanerochaete chrysosporium.Molecular genetics and genomics : MGG, , 274 (5 ) ,454-66 More Information

Khan, Izhar U H; Selvaraju, Suresh B; Yadav, Jagjit S (2005. ) Occurrence and characterization of multiple novel genotypes of Mycobacterium immunogenum and Mycobacterium chelonae in metalworking fluids.FEMS microbiology ecology, , 54 (3 ) ,329-38 More Information

Khan, Izhar U H; Selvaraju, Suresh B; Yadav, Jagjit S (2005. ) Method for rapid identification and differentiation of the species of the Mycobacterium chelonae complex based on 16S-23S rRNA gene internal transcribed spacer PCR-restriction analysis.Journal of clinical microbiology, , 43 (9 ) ,4466-72 More Information

Doddapaneni, Harshavardhan; Chakraborty, Ranajit; Yadav, Jagjit S (2005. ) Genome-wide structural and evolutionary analysis of the P450 monooxygenase genes (P450ome) in the white rot fungus Phanerochaete chrysosporium: evidence for gene duplications and extensive gene clustering.BMC genomics, , 6 ,92 More Information

Doddapaneni, Harshavardhan; Subramanian, Venkataramanan; Yadav, Jagjit S (2005. ) Physiological regulation, xenobiotic induction, and heterologous expression of P450 monooxygenase gene pc-3 (CYP63A3), a new member of the CYP63 gene cluster in the white-rot fungus Phanerochaete chrysosporium.Current microbiology, , 50 (6 ) ,292-8 More Information

Selvaraju, Suresh B; Khan, Izhar U H; Yadav, Jagjit S (2005. ) A new method for species identification and differentiation of Mycobacterium chelonae complex based on amplified hsp65 restriction analysis (AHSPRA).Molecular and cellular probes, , 19 (2 ) ,93-9 More Information

Selvaraju, Suresh B; Khan, Izhar U H; Yadav, Jagjit S (2005. ) Biocidal activity of formaldehyde and nonformaldehyde biocides toward Mycobacterium immunogenum and Pseudomonas fluorescens in pure and mixed suspensions in synthetic metalworking fluid and saline.Applied and environmental microbiology, , 71 (1 ) ,542-6 More Information

Doddapaneni, Harshavardhan; Yadav, Jagjit S (2004. ) Differential regulation and xenobiotic induction of tandem P450 monooxygenase genes pc-1 (CYP63A1) and pc-2 (CYP63A2) in the white-rot fungus Phanerochaete chrysosporium.Applied microbiology and biotechnology, , 65 (5 ) ,559-65 More Information

Khan, Izhar U H; Yadav, Jagjit S (2004. ) Real-time PCR assays for genus-specific detection and quantification of culturable and non-culturable mycobacteria and pseudomonads in metalworking fluids.Molecular and cellular probes, , 18 (1 ) ,67-73 More Information

Khan, Izhar U H; Yadav, Jagjit S (2004. ) Development of a single-tube, cell lysis-based, genus-specific PCR method for rapid identification of mycobacteria: optimization of cell lysis, PCR primers and conditions, and restriction pattern analysis. Journal of clinical microbiology, , 42 (1 ) ,453-7

Yadav, Jagjit S; Khan, Izhar U H; Fakhari, Farnaz; Soellner, Mathew B (2003. ) DNA-based methodologies for rapid detection, quantification, and species- or strain-level identification of respiratory pathogens (Mycobacteria and Pseudomonads) in metalworking fluids.Applied occupational and environmental hygiene, , 18 (11 ) ,966-75 More Information

Yadav, Jagjit S; Soellner, Matthew B; Loper, John C; Mishra, Prashant K (2003. ) Tandem cytochrome P450 monooxygenase genes and splice variants in the white rot fungus Phanerochaete chrysosporium: cloning, sequence analysis, and regulation of differential expression. Fungal genetics and biology : FG & B, , 38 (1 ) ,10-21

Yadav, J S; Lawrence, D L; Nuck, B A; Federle, T W; Reddy, C A (2001. ) Biotransformation of linear alkylbenzene sulfonate (LAS) by Phanerochaete chrysosporium: oxidation of alkyl side-chain. Biodegradation, , 12 (6 ) ,443-53

Yadav, J S; Bethea, C; Reddy, C A (2000. ) Mineralization of trichloroethylene (TCE) by the white rot fungus Phanerochaete chrysosporium. Bulletin of environmental contamination and toxicology, , 65 (1 ) ,28-34

Yadav, J S; Loper, J C (2000. ) Cloning and characterization of the cytochrome P450 oxidoreductase gene from the zygomycete fungus Cunninghamella.Biochemical and biophysical research communications, , 268 (2 ) ,345-53 More Information

Yadav, J S; Loper, J C (2000. ) Cytochrome P450 oxidoreductase gene and its differentially terminated cDNAs from the white rot fungus Phanerochaete chrysosporium. Current genetics, , 37 (1 ) ,65-73

Yadav, J S; Loper, J C (1999. ) Multiple p450alk (cytochrome P450 alkane hydroxylase) genes from the halotolerant yeast Debaryomyces hansenii. Gene, , 226 (2 ) ,139-46

Yadav, J S; Quensen, J F; Tiedje, J M; Reddy, C A (1995. ) Degradation of polychlorinated biphenyl mixtures (Aroclors 1242, 1254, and 1260) by the white rot fungus Phanerochaete chrysosporium as evidenced by congener-specific analysis. Applied and environmental microbiology, , 61 (7 ) ,2560-5

Yadav, J S; Wallace, R E; Reddy, C A (1995. ) Mineralization of mono- and dichlorobenzenes and simultaneous degradation of chloro- and methyl-substituted benzenes by the white rot fungus Phanerochaete chrysosporium. Applied and environmental microbiology, , 61 (2 ) ,677-80

Yadav, J S; Reddy, C A (1993. ) Mineralization of 2,4-Dichlorophenoxyacetic Acid (2,4-D) and Mixtures of 2,4-D and 2,4,5-Trichlorophenoxyacetic Acid by Phanerochaete chrysosporium. Applied and environmental microbiology, , 59 (9 ) ,2904-8

Yadav, J S; Reddy, C A (1993. ) Degradation of benzene, toluene, ethylbenzene, and xylenes (BTEX) by the lignin-degrading basidiomycete Phanerochaete chrysosporium. Applied and environmental microbiology, , 59 (3 ) ,756-62

Yadav, J S; Tripathi, J P (1991. ) Optimization of cultivation and nutrition conditions and substrate pretreatment for solid-substrate fermentation of wheat straw by Coriolus versicolor. Folia microbiologica, , 36 (3 ) ,294-301

Yadav, J S (1988. ) SSF of wheat straw with alcaliphilic Coprinus.Biotechnology and bioengineering, , 31 (5 ) ,414-7 More Information

Keywords

Metalworking fluids, mycotoxins, allergenic fungi, toxigenic fungi, P450, bioremediation ,Technology, Industry, and Agriculture(MeSH J01),Bacteria(MeSH B03),Viruses(MeSH B04),Algae and Fungi(MeSH B05),Bacterial Infections and Mycoses(MeSH C01),Respiratory Tract Diseases(MeSH C08),Immunologic Diseases(MeSH C20),Disorders of Environmental Origin(MeSH C21),Polycyclic Hydrocarbons(MeSH D04),Enzymes, Coenzymes, and Enzyme Inhibitors(MeSH D08),Investigative Techniques(MeSH E05),Environment and Public Health(MeSH G03),Biological Phenomena, Cell Phenomena, and Immunity(MeSH G04),Biochemical Phenomena, Metabolism, and Nutrition(MeSH G06)

Contact Information

Research - University of Cincinnati College of Medicine
Department of Environmental Health
Cincinnati  Ohio, 45267-0056
Phone: 513-558-4806
Fax: 513-558-4397
jagjit.yadav@uc.edu