Zhenyu Yuan

Peer Reviewed Publications

Collins, Kelly J; Yuan, Zhenyu; Kovall, Rhett A  (2014). Structure and function of the CSL-KyoT2 corepressor complex: a negative regulator of notch signaling. Structure (London, England : 1993), 22 (1) , 70-81More Information

Yuan, Zhenyu; Friedmann, David R; VanderWielen, Bradley D; Collins, Kelly J; Kovall, Rhett A  (2012). Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2. The Journal of biological chemistry, 287 (42) , 34904-16More Information

Maier, Dieter; Kurth, Patricia; Schulz, Adriana; Russell, Andrew; Yuan, Zhenyu; Gruber, Kim; Kovall, Rhett A; Preiss, Anette  (2011). Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster. Molecular biology of the cell, 22 (17) , 3242-52More Information

VanderWielen, Bradley D; Yuan, Zhenyu; Friedmann, David R; Kovall, Rhett A  (2011). Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes. The Journal of biological chemistry, 286 (17) , 14892-902More Information

Bahassi, El Mustapha; Yin, Moying; Robbins, Susan B; Li, Ya-Qin; Conrady, Deborah G; Yuan, Zhenyu; Kovall, Rhett A; Herr, Andrew B; Stambrook, Peter J  (2011). A human cancer-predisposing polymorphism in Cdc25A is embryonic lethal in the mouse and promotes ASK-1 mediated apoptosis. Cell division, 6 (1) , 4More Information

Chen, Zhuo; Zhang, Kun; Zhang, Xin; Yuan, Xiao H; Yuan, Zhenyu; Jin, Li; Xiong, Momiao  (2003). Comparison of gene expression between metastatic derivatives and their poorly metastatic parental cells implicates crucial tumor-environment interaction in metastasis of head and neck squamous cell carcinoma. Clinical & experimental metastasis, 20 (4) , 335-42

Contreras, Ashley N; Yuan, Zhenyu; Kovall, Rhett A  (2015). Thermodynamic binding analysis of Notch transcription complexes from Drosophila melanogaster. Protein science : a publication of the Protein Society, 24 (5) , 812-22More Information

Tabaja, Nassif; Yuan, Zhenyu; Oswald, Franz; Kovall, Rhett A  (2017). Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes. The Journal of biological chemistry, 292 (25) , 10549-10563More Information

Yuan, Zhenyu; Praxenthaler, Heiko; Tabaja, Nassif; Torella, Rubben; Preiss, Anette; Maier, Dieter; Kovall, Rhett A  (2016). Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster. PLoS biology, 14 (7) , e1002509More Information

Gomez-Lamarca, Maria J; Falo-Sanjuan, Julia; Stojnic, Robert; Abdul Rehman, Sohaib; Muresan, Leila; Jones, Matthew L; Pillidge, Zoe; Cerda-Moya, Gustavo; Yuan, Zhenyu; Baloul, Sarah; Valenti, Phillippe; Bystricky, Kerstin; Payre, Francois; O'Holleran, Kevin; Kovall, Rhett; Bray, Sarah J  (2018). Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics. Developmental cell, 44 (5) , 611-623.e7More Information

Nagel, Anja C; Auer, Jasmin S; Schulz, Adriana; Pfannstiel, Jens; Yuan, Zhenyu; Collins, Courtney E; Kovall, Rhett A; Preiss, Anette  (2017). Phosphorylation of Suppressor of Hairless impedes its DNA-binding activity. Scientific reports, 7 (1) , 11820More Information