Ge Zhang , PhD

My long-term research objective is to understand the genetic, molecular, and evolutionary architecture of human complex traits in a quantitatively rigorous framework. Such research will lead to a deeper understanding of how genetic variations, gene-gene and gene-environment interactions produce complex phenotypes. An exciting and challenging aspect of this research is that it is inherently interdisciplinary, existing at the interface of genetics, biology, and mathematics.

Grant: #1017289 Investigators:Ball, William; Zhang, Ge 06-01-2017 -03-31-2021 Burroughs Wellcome Fund Genomic study of gestational length and preterm birth Role:Collaborator $600,000.00 Active Level:Private Non-Profit

Peer Reviewed Publications

Karns, Rebekah; Zhang, Ge; Jeran, Nina; Havas-Augustin, Dubravka; Missoni, Sasa; Niu, Wen; Indugula, Subba Rao; Sun, Guangyun; Durakovic, Zijad; Narancic, Nina Smolej; Rudan, Pavao; Chakraborty, Ranajit; Deka, Ranjan (2011. ) Replication of genetic variants from genome-wide association studies with metabolic traits in an island population of the Adriatic coast of Croatia.European journal of human genetics : EJHG, , 19 (3 ) ,341-6 More Information

Zhang, Ge; Karns, Rebekah; Narancic, Nina Smolej; Sun, Guangyun; Cheng, Hong; Missoni, Sasa; Durakovic, Zijad; Rudan, Pavao; Chakraborty, Ranajit; Deka, Ranjan (2010. ) Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.PloS one, , 5 (4 ) ,e10375 More Information

Deka, Ranjan; Xu, Ling; Pal, Prodipto; Toelupe, Palanitina T; Laumoli, Tuiasina S; Xi, Huifeng; Zhang, Ge; Weeks, Daniel E; McGarvey, Stephen T (2009. ) A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans.BMC medical genetics, , 10 ,143 More Information

Bernstein, Jonathan A; Zhang, Ge; Jin, Li; Abbott, Carol; Nebert, Daniel W (2008. ) Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis.The Journal of asthma : official journal of the Association for the Care of Asthma, , 45 (4 ) ,287-92 More Information

Nebert, Daniel W; Zhang, Ge; Vesell, Elliot S (2008. ) From human genetics and genomics to pharmacogenetics and pharmacogenomics: past lessons, future directions.Drug metabolism reviews, , 40 (2 ) ,187-224 More Information

Zhang, Ge; Nebert, Daniel W; Chakraborty, Ranajit; Jin, Li (2006. ) Statistical power of association using the extreme discordant phenotype design.Pharmacogenetics and genomics, , 16 (6 ) ,401-13 More Information

Martin, Tammy M; Zhang, Ge; Luo, Jingchun; Jin, Li; Doyle, Trudy M; Rajska, Barbara M; Coffman, Jessica E; Smith, Justine R; Becker, Matthias D; Mackensen, Friederike; Khan, Muhammad A; Levinson, Ralph D; Schumacher, H Ralph; Wade, N Kevin; Rosenbaum, James T; Reveille, John D (2005. ) A locus on chromosome 9p predisposes to a specific disease manifestation, acute anterior uveitis, in ankylosing spondylitis, a genetically complex, multisystem, inflammatory disease.Arthritis and rheumatism, , 52 (1 ) ,269-74 More Information

Jin, Li; Zhang, Ge; Akey, Joshua M; Luo, Jingchun; Lee, Juwon; Weisman, Michael H; Bruckel, Jane; Inman, Robert D; Stone, Millicent A; Khan, Muhammad A; Schumacher, H Ralph; Maksymowych, Walter P; Mahowald, Maren L; Sawitzke, Allen D; Vasey, Frank B; Yu, David T Y; Reveille, John D (2004. ) Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility.Arthritis and rheumatism, , 50 (9 ) ,3047-8 More Information

Zhang, Ge; Luo, Jingchun; Bruckel, Jane; Weisman, Michael A; Schumacher, H Ralph; Khan, Muhammad A; Inman, Robert D; Mahowald, Maren; Maksymowych, Walter P; Martin, Tammy M; Yu, David T Y; Stone, Millicent; Rosenbaum, James T; Newman, Patricia; Lee, Juwon; McClain, Jo A; West, O Clark; Jin, Li; Reveille, John D (2004. ) Genetic studies in familial ankylosing spondylitis susceptibility.Arthritis and rheumatism, , 50 (7 ) ,2246-54 More Information

Akey, Joshua M; Zhang, Ge; Zhang, Kun; Jin, Li; Shriver, Mark D (2002. ) Interrogating a high-density SNP map for signatures of natural selection.Genome research, , 12 (12 ) ,1805-14 More Information

Ma, Yongxin; Zhang, Sizhong; Xia, Qinjie; Zhang, Ge; Huang, Xinli; Huang, Mingkong; Xiao, Cuiying; Pan, Agen; Sun, Yan; Lebo, Roger; Milunsky, Aubrey (2002. ) Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide. Molecular human reproduction, , 8 (1 ) ,24-31

Ding, Lan; Zhang, Sizhong; Qiu, Weimin; Xiao, Cuiying; Wu, Shaoqing; Zhang, Ge; Cheng, Lu; Zhang, Sixiao (2002. ) Novel mutations of PKD1 gene in Chinese patients with autosomal dominant polycystic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , 17 (1 ) ,75-80

Research - Office
333 Burnet Avenue
Cincinnati  Ohio, 45229
ge.zhang@cchmc.org