Xiang Zhu

Bachelor of Clinical Medicine: Nanjing Medical University, Nanjing, China, 2000

Doctor of Philosophy: Nanjing Medical University, Nanjing, China, 2005

American Board of Pathology (Anatomic and Clinical Pathology) (Certification Date: 06-08-2024 )

Pathology

Pathology

Pathology-Anatomic and Clinical

Peer Reviewed Publications

Rubinstein, Jeremy D; Zhu, Xiang; Leemhuis, Thomas; Pham, Giang; Ray, Lorraine; Emberesh, Sana; Jodele, Sonata; Thomas, Shawn; Cancelas, Jose A; Bollard, Catherine M; Hanley, Patrick J; Keller, Michael D; Grimley, Olivia; Clark, Diana; Clark, Teri; Lindestam Arlehamn, Cecilia S; Sette, Alessandro; Davies, Stella M; Nelson, Adam S; Grimley, Michael S; Lutzko, Carolyn  (2021). Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted. Blood advances, 5 (17) , 3309-3321More Information

Laskin, Benjamin L; Denburg, Michelle R; Furth, Susan L; Moatz, Taylor; Altrich, Michelle; Kleiboeker, Steve; Lutzko, Carolyn; Zhu, Xiang; Blackard, Jason T; Jodele, Sonata; Lane, Adam; Wallace, Gregory; Dandoy, Christopher E; Lake, Kelly; Duell, Alexandra; Litts, Bridget; Seif, Alix E; Olson, Timothy; Bunin, Nancy; Davies, Stella M  (2020). The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (12) , 3044-3054More Information

Nelson, Adam S; Heyenbruch, Daria; Rubinstein, Jeremy D; Sabulski, Anthony; Jodele, Sonata; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S  (2020). Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients. Blood advances, 4 (22) , 5745-5754More Information

Rubinstein, Jeremy D; Zhu, Xiang; Lutzko, Carolyn; Leemhuis, Tom; Cancelas, Jose A; Jodele, Sonata; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S; Nelson, Adam S  (2020). Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy. Blood advances, 4 (14) , 3252-3257More Information

Verma, Alok K; Kandikattu, Hemanth Kumar; Manohar, Murli; Shukla, Anshi; Upparahalli Venkateshaiah, Sathisha; Zhu, Xiang; Mishra, Anil  (2019). Intestinal overexpression of IL-18 promotes eosinophils-mediated allergic disorders. Immunology, 157 (2) , 110-121More Information

Legrand, Fanny; Cao, Yun; Wechsler, Joshua B; Zhu, Xiang; Zimmermann, Nives; Rampertaap, Shakuntala; Monsale, Joseph; Romito, Kimberly; Youngblood, Bradford A; Brock, Emily C; Makiya, Michelle A; Tomasevic, Nenad; Bebbington, Christopher; Maric, Irina; Metcalfe, Dean D; Bochner, Bruce S; Klion, Amy D  (2019). Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies. The Journal of allergy and clinical immunology, 143 (6) , 2227-2237.e10More Information

Venkateshaiah, Sathisha Upparahalli; Zhu, Xiang; Rajavelu, Priya; Niranjan, Rituraj; Manohar, Murli; Verma, Alok K; Lasky, Joseph A; Mishra, Anil  (2018). Regulatory effects of IL-15 on allergen-induced airway obstruction. The Journal of allergy and clinical immunology, 141 (3) , 906-917.e6More Information

Zhu, Xiang; Hogan, Simon P; Molkentin, Jeffery D; Zimmermann, Nives  (2016). Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils. American journal of physiology. Gastrointestinal and liver physiology, 310 (8) , G609-17More Information

Zhu, Xiang; Mose, Eucabeth; Hogan, Simon P; Zimmermann, Nives  (2014). Differential eosinophil and mast cell regulation: mast cell viability and accumulation in inflammatory tissue are independent of proton-sensing receptor GPR65. American journal of physiology. Gastrointestinal and liver physiology, 306 (11) , G974-82More Information

Rayapudi, Madhavi; Rajavelu, Priya; Zhu, Xiang; Kaul, Ajay; Niranjan, Rituraj; Dynda, Scott; Mishra, Akanksha; Mattner, Jochen; Zaidi, Asifa; Dutt, Parmesh; Mishra, Anil  (2014). Invariant natural killer T-cell neutralization is a possible novel therapy for human eosinophilic esophagitis. Clinical & translational immunology, 3 (1) , e9More Information

Zhu, Xiang; Mose, Eucabeth; Zimmermann, Nives  (2013). Proton channel HVCN1 is required for effector functions of mouse eosinophils. BMC immunology, 14, 24More Information

Rayapudi, Madhavi; Mavi, Parm; Zhu, Xiang; Pandey, Akhilesh K; Abonia, J Pablo; Rothenberg, Marc E; Mishra, Anil  (2010). Indoor insect allergens are potent inducers of experimental eosinophilic esophagitis in mice. Journal of leukocyte biology, 88 (2) , 337-46More Information

Zhu, Xiang; Wang, Meiqin; Mavi, Parm; Rayapudi, Madhavi; Pandey, Akhilesh K; Kaul, Ajay; Putnam, Philip E; Rothenberg, Marc E; Mishra, Anil  (2010). Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice. Gastroenterology, 139 (1) , 182-93.e7More Information

Zhu, Xiang; Wang, Meiqin; Crump, Caleb H; Mishra, Anil  (2009). An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice. American journal of physiology. Gastrointestinal and liver physiology, 297 (3) , G550-8More Information

Zhu, Xiang; Schweitzer, Brock L; Romer, Eric J; Sulentic, Courtney E W; DeKoter, Rodney P  (2008). Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling. European journal of immunology, 38 (9) , 2587-99More Information

Kamath, M B; Houston, I B; Janovski, A J; Zhu, X; Gowrisankar, S; Jegga, A G; DeKoter, R P  (2008). Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity. Leukemia, 22 (6) , 1214-25More Information

Book Chapter

Zhu X, Zimmermann N. (2013). Eosinophil chemotaxis.. In Eosinophils in Health and Disease . (pp. 121). New York, Elsevier

2006-2006 Postdoctoral Fellow, Medical College of Georgia, , Augusta, GA

2006-2008 Postdoctoral Fellow, University of Cincinnati College of Medicine, , Cincinnati, Ohio

2008-2020 Research Associate, Children’s Hospital Medical Center, , Cincinnati, Ohio

UCMC Pathology
234 Goodman Street
Cincinnati  Ohio, 45219
Phone: 513-584-7284
Fax: 513-584-3892
zhux2@ucmail.uc.edu