• 55All Colleges/Departments
  • 27Childrens Hospital Medical Center
  • 17College of Medicine
  • 5College of Arts and Sciences
  • 4CEAS - College of Eng & Appl Science
  • 1CECH Educ Criminal Justice & Human Srvcs
  • 1College of Allied Health Sciences
  • Advanced Materials Characterization Center (AMCC)

    Melodie Fickenscher

    The Advanced Materials Characterization Center is a research facility located in the College of Engineering at the University of Cincinnati. The AMCC provides access to electron microscopes, x-ray diffraction, and a variety of other analytical instrumentation. Training and sample evaluation is available to researchers within the UC community, as well as external universities and companies.
  • Animal Behavioral Core (CCHMC)

    Charles V. Vorhees

    Our behavioral and nonbehavioral assays will help you characterize the nervous system function in mice and rats. There is no fee for our services. Our mission is to form collaborative partnerships with researchers that will benefit science. Our measurement protocols include video tracking and photocell technology.
  • Biosafety Level 3 Facility (BSL3)

    Gary Dean, PhD, Director

    Laboratory environment suitable for working with BSL3 agents.

    Please contact the Director for additional details.
  • Biostatistical Consulting Unit

    Matthew Fenchel

  • Cardiovascular Imaging Core

    Thomas Kimball, MD

    Access to the right imaging technology and services can greatly enhance your ability to conduct cardiovascular research. The Cardiovascular Imaging Core Research Laboratory provides a wide range of imaging techniques to investigators at Cincinnati Childrens, and offers consulting services ranging from educational seminars to assistance with grant and industry funding support
  • Cell Manipulations Laboratory (CCHMC)

    Carolyn Lutzko

    We offer a controlled-access clean room facility that was designed and built to perform ex vivo cell manipulations, including gene therapy protocols and pluripotent stem cell protocols, for Phase 1 and 2 clinical trials.
  • Cell Processing Core

    Carolyn Lutzko

    The Cell Processing Core offers a variety of human hematopoietic cells or other products to investigators for their research programs. The Core can provide specific cell populations such as total nucleated cells, low density mononuclear cells or CD34+ cells from bone marrow, umbilical cord blood, peripheral blood or G-CSF mobilized peripheral blood through a Normal Donor Repository. Other enriched cell populations may be available via special request. The Core can also provide unprocessed samples, plasma or serum. 
  • Center for Biological Microscopy (CBM)

    Birgit Ehmer

    To assist the researcher in generating high-resolution, high quality, microscopy-based data for publications and presentation at professional venues. A range of services is available for both experienced and inexperienced users. Experienced users may use the Center's instruments after orientation by a staff member. Inexperienced users may choose to receive training in the use of the instruments, technical support in microscopy and image analysis, consultation in experimental design, or have us perform the microscopy for them as a service.
  • Center for Biostatistical Services (CBS)

    Mario Medvedovic

    The mission of this center is to support research in the College of Medicine (COM) by connecting biomedical scientists with the joint expertise of the faculty, staff and graduate students in the Division of Biostatistics and Bioinformatics. The joint expertise of CBS faculty covers a wide range of biostatistics and bioinformatics topics. CBS provides the venue for obtaining short-term consulting support and for establishing long-term collaborations with CBS faculty. Please see the listing of our faculty and their expertise to select the appropriate contact.

    CBS provides support for manuscript preparation, grant applications and other projects requiring biostatistics and bioinformatics support via several types of consulting:

    1.    Initial planning meeting. Initial one hour meeting to discuss project, objectives and establish the level of support that will be needed is free.

    2.    Short-Term Consultation. Short term consultation support is given for well-defined research projects where funds for fee-for-service charges have been secured. This service may also be used to secure biostatistical support for funded projects (grants, contracts) where the scope of work is small enough not to warrant the commitment of CBS  faculty on a percent time effort basis.

    3.     Funded Projects. Biostatistics and bioinformatics services for funded projects can be provided on fee-for-service basis, or at a fixed support level via FTE support for involved faculty and staff.

    4.     Grant application and Research Protocols. CBS faculty provide biostatistics and bioinformatics services for individual-initiated grant applications or research protocols at all stages of grant preparation and project execution. It is expected that pre-application services will be funded through one of the existing mechanisms, while support during the project-execution period will be provided by including CBS faculty and staff as collaborators with the adequate FTE support.  Pre-application services alone can be provided on fee-for-service bases when no need for the support during the project execution is envisioned.

    5.    Research Unit/Research Group Support. CBS faculty can provide biostatistics and bioinformatics support for whole research groups and academic units.  Such arrangements may cover biostatistical, bioinformatics as well as educational needs of faculty, research staff and students collaborating research unit. Such support can be provided on a percent effort basis.

    6.    Research Central Initiated Projects. We also provide biostatistics and bioinformatics support to investigators who are CCTST members and request assistance through Research Central: the portal for intake of CCTST requests. The CCTST provides vouchers, upon approval of the application. Please contact the visit the CCTST website for more information.
  • Center for Clinical and Translational Science and Training (CCTST)

    James Heubi, MD, Director

    Research across the Academic Health Center (AHC) is supported by the Center for Clinical and Translational Science and Training (CCTST). The CCTST coordinates a wide range of services, including biostatistics, biomedical informatics, data management, training grant application assistance, inpatient and outpatient clinical research services.
    Full details and services for the CCTST are available through their website at https://cctst.uc.edu

    Location and Hours:
    This join institutional core is located at Cincinnati Children's Hospital Medical Center, Location S, Room 10.300.  It is open M-F from 8A-5P or by appointment at 513 803-2612.
  • Center for Health Informatics (CHI)

    Center for Health Informatics

    The Center for Health Informatics is a University of Cincinnati service core focused on providing research data for departments in the UC College of Medicine and UC Health. Dedicated to assisting all research efforts, we provide initial study design and feasibility services at no cost through UC’s Center for Clinical & Translational Science & Training.

    The Center for Health Informatics is the designated honest broker to access UC Health patient data for research. All data requests for research purposes should be routed through our office. We maintain a close relationship with the Institutional Review Board and Office of Research to ensure data are properly accessed, delivered and logged based on university compliance requirements and federal law. We are experts in the process of de-identifying data sets. We will help you gain fast, efficient, compliant access to the data you need.

    Most clinical data requests are completed in less than two business days, while technology and analytics projects tend to be more involved. If your department participates in research, we urge you to consider research data management in your budget and grant planning.

    Biomedical data informatics
    • Query and use of electronic health record data
    • Data acquisition and integration
    • Honest broker service
    • Big/complex data analysis
    • Molecular data analysis
    • Healthcare analytics
    Application and technology development  Custom software development
    • Mobile application development
    • EHR-based tools for research
    • Clinical decision support systems
    • Custom web development
    • Specialty database, datamart, and research registry development
    • Electronic (e-consent) on the iPad for non-FDA studies
    Grant/protocol/manuscript development and review
    Informatics education and training
    • Formal informatics education programs
    • Participatory learning and training programs
    Informatics consulting and collaboration
  • Chemical Sensors & Biosensors

    Necati Kaval

    See the associated equipment listings for information on the specific chemical measurement instruments.
  • Cincinnati Biobank Core Facility (CCHMC)

    Beth Cob

    We aim to promote world-class biomedical research by ensuring availability of the highest quality biospecimens to meet researchers’ needs. We provide access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research. These services are available to researchers at Cincinnati Children’s Hospital Medical Center, surrounding academic centers and beyond. We are also home to the Better Outcomes for Children (BofC) biorepository. BofC is an institution-wide initiative to collect and store leftover clinical samples for research use.
  • Clinical Studies Participant Recruitment Service

    Sara Keegan, Clinical Research Manager

    Mission: 
    The Participant Recruitment and Clinical Research Service Center is a unique resource provided by the University Of Cincinnati Department Of Emergency Medicine to support research conducted across the Academic Health Center. The Center is staffed by a team of clinical research coordinators (CRC). Together, they provide a centralized, coordinated approach to screening and recruiting patients for research participation, collecting and processing specimen samples and data, and entering data into clinical trial databases. 

    Location & Hours: 
    CRCs are fully integrated into the Emergency Department at University of Cincinnati Medical Center, West Chester and Jewish hospitals, where they work in tandem with the clinical team. The Center staff is available 24hrs/day, 7 days/week.

    Services: 
    General Screening Services - $625/month (Internal); $995/month (External)
    • CRC availability 24hrs/day for screening and identification of potential study participants and/or healthy controls by monitoring newly-arrived Emergency Department patients through all available means, including patient tracking systems, ED rounds, and electronic health record review.
    Clinical Research Coordinator (CRC) Services - $37.50/hr (Internal); $60/hr (External) 
    • Study-specific screen – detailed screening assessment to determine inclusion/exclusion criteria, may include medical record review, consultation with treatment team, patient interview and/or assessment
    • Enrollment & consenting – move forward with enrollment of patients who agree to participate in an active therapeutic, interventional research study; this may include additional screening activities
    • Study-specific procedures/assessments – protocol specific procedures/assessments
    • Phlebotomy –  single-stick, blood draws for collection, analysis or shipping
    • Follow-Up – assist with telephone and interview follow-up procedures with enrolled subjects
    • Data/chart abstraction – medical record review to glean data for case report form completion
    • Training – each CRC is required to be trained on each new study protocol

     
  • Comprehensive Mouse and Cancer Core (CCHMC)

    Hartmut Geiger, PhD

    The Comprehensive Mouse and Cancer Core within the Division of Experimental Hematology and Cancer Biology at Cincinnati Children’s offers a number of services for researchers exploring cancer systems through animal models. The core is directed by  Hartmut Geiger. We provide animals from specific inbred mouse strains primarily used in cancer and hematopoietic research, offer cell transplant, harvest and irradiation services and can handle animal cancer model systems involving xenotransplant procedures.
  • Confocal Imaging Core (CCHMC)

    Matthew Kofron

    We will train you to use state-of-the-art confocal microscopes for your research. We provide access to confocal microscopes, deconvolution microscopes and computer analysis workstations. Once you’ve been trained by our staff, you may access our facilities 24 hours a day.
  • Critical Care MediaLab

    Ken Tegtmeyer, MD

    The Critical Care MediaLab develops high-quality video and animation to enhance medical education. Our expertise lies in clinical video and video editing as well as 3D animation.
  • Data Management Center

    Rachel Akers

    The Data Management Center (DMC) at Cincinnati Children’s supports researchers, and aims to improve clinical outcomes by leading the development of state-of-the-art data management. The DMC resides within the Division of Biostatistics and Epidemiology.
  • DNA Sequencing and Genotyping Facility

    Xueguang Sun

    We specialize in sequencing with template preparation from bacterial cultures, sequencing without template preparation and electrophoresis.
  • Engineering Research Center (ERC) Cleanroom

    Ian Papautsky

    The Engineering Research Center Clean Room is a central fabrication, processing, and characterization center intended to be used by a diverse campus wide research community. The more than 8000 square foot facility includes areas of class 10, 100, 1000, and 10,000 clean room spaces.  It includes lithography, deposition, etching, oxidation, diffusion, and characterization tools from nanoscale to microscale device fabrication.
  • Environmental Analysis Service Center (EASC)

    Dr. George Sorial

    The Environmental Analysis Service Center (EASC) at University of Cincinnati is located on the 7th floor in Engineering Research Center on the uptown west campus of U. of Cincinnati. The EASC supports the application of mass spectrometry techniques in the field of chemistry, environmental sciences, pharmaceutical sciences, life sciences and medicine. Typically, we provide services of mass spectrometry analysis for non-targeted compound screening, impurity analysis, metabolomics, and molecular formula assignments for ACS publications (Accurate Mass Measurement or High Resolution Mass Spectrometry [HRMS]).  The EASC holds competitive rates with high quality data and fast turn-around time. We offer services to Universities, public agencies, and private corporations.  We look forward to serving your needs for mass spectrometry analysis. 

    If you need mass spectrometry analysis services, EASC is a choice.  EASC has the expertise to analyze your samples and provide you with solid data. For more information about the center, please visit our website at www.easc-uc.org.

    Photos and descriptions of lab instrumentation are on-line at: http://seebme.ceas.uc.edu/Research_Centers/EASC/Lab_Instrumentation.html
  • FACScalibur/Flow Cytometry Core

    William Miller PhD

    A FACSCalibur four color flow cytometer system is available for use by researchers. The instrument is available seven days a week 24 hours per day in CARE 2876.

    For access to the instrument and the online calendar, please contact Dr. Miller.
  • Fernald Database and Biospecimens Service

    Susan Pinney

    Mission: To provide a mechanism for sharing data and biospecimen from a large longitudinal cohort as a resource to researchers for approved studies.
     
    Description:  The Fernald Community Cohort consists of the 9782 persons who were enrolled in the Fernald Medical Monitoring Program (FMMP)(1990-2008). The comprehensive examinations conducted as part of the Fernald Medical Monitoring Program (FMMP) began in the autumn of 1990. The FMMP provided 9,782 initial examinations and 42,775 re-examinations over 18 years. An extensive computerized database and biospecimen repository was created to provide research resources for future studies. All questionnaire, examination and diagnostic procedure data collected from the FMMP were coded by certified medical record coders, double entered with verification into a SAS database on site of the examinations. Cryo-preserved blood and urine samples were collected at enrollment and at various intervals throughout follow-up.  At the first examination three 1-ml aliquots of whole blood, plasma, serum, urine and urine with buffer were obtained from each participant (15 aliquots per person) for future analyses.  Additional whole blood and serum was obtained in 1996-1997 and 2006-2008. Specimens have been stored in minus 80 degree freezers; over 160,000 biospecimens are in the archive. More information about the cohort and the “Access to Data and Biospecimen Policy” and application form can be found at www.eh.uc.edu/fmmp/research.
  • Gene Expression Core (CCHMC)

    S. Steven Potter, PhD

    If your research involves the study of developmental and disease processes, we can help you perform expression level analysis of thousands of genes in parallel. We use commercial microarrays available from Affymetrix and Illumina. We offer data analysis and guidance on preparing RNA for labeling.
  • Genomics, Epigenomics and Sequencing Core (GESC)

    Xiang Zhang, PhD, Core Manager

    The Genomics, Epigenomics and Sequencing Core (GESC), originally named as Sequencing and Microarray Laboratory, was established in 1999. GESC is a fee-for-service, one-stop facility that provides genomics and epigenomics related service and collaboration to researchers at the University of Cincinnati, Cincinnati Children's Hospital and other institutions.
    In 2012, GESC was transformed into the next generation sequencing-based core facility. Since then, it has been expanding its services and seamlessly integrated with the bioinformatics team for handling massive amounts of data generated by these services. Equipped with Illumina sequencer and automated liquid handling system, GESC provides a wide variety of high-quality NGS services and continuously developing new methodologies to meet researchers’ requirements. In addition, it offers Illumina BeadChip assay and a series of other supportive services. The Core manager Xiang Zhang routinely provides consultation to researchers from sample preparation to experiment design.
    GESC is a small but highly efficient team. Nearly 100% of its expenses is paid from its service revenue. The Core’s financial status is extraordinary healthy and stable.
  • Imaging Research Center

    Charles Dumoulin, PhD

    We make modern imaging technology available to researchers. Services include a whole-body scanner with EEG monitoring, clinical MRI scanners, CT, PET-CT and gamma camera and scanners, fluoroscopy systems and longitudinal imaging for animals. 
  • Inhalation Core Facility

    Jennifer Flury

    The mission of the Inhalation Core Facility is to provide a controlled exposure system to mimic both first hand cigarette smoke exposure and second hand smoke exposure using a whole body exposure system.  In addition, we can provide individual mouse organs, serum, and cigarette smoke extract.

    Location & Hours:
    The core is located in the Cardiovascular Research Center (CVC) Room 4947. 
     
  • Investigational Pharmacy

    Denise Lagory, RPh

    The Cincinnati Children's Hospital Investigational Drug Service (IDS) provides services customized to each research protocol conducted at Cincinnati Children's. These services include randomization, inventory maintenance, all aspects of drug accountability, compounding and preparation of blinded dosage forms, developing pre-printed order forms and dispensing investigational drugs according to protocol. The IDS is responsible for both inpatient and outpatient investigational medication dispensing for industry sponsored, grant funded and investigator initiated protocols.
  • Live Microscopy Core

    Chet Closson, Manager

    The Live Microscopy facility is designed to help investigators perform high resolution imaging with either living or fixed specimens. The facility has two advanced Zeiss confocal laser scanning microscopes for use, including one equipped for multiphoton imaging, as well as a Leica DMi8 widefield microscope system, and various stereo and dissection microscopes. Additional equipment available for use are a Laser Capture Microdissection instrument, multimode plate reader, Real-Time-PCR systems, infrared imager, and cryostat.

    Location & Hours:
    The core is located in Medical Sciences Building Room 3155. It is open 24/7 for approved trained users, or from 9 am to 5 pm, Monday through Friday for technical assistance.
  • Mass Spectrometry Facility

    Pat Limbach

    Our facility is dedicated to inorganic, organic and biological mass spectrometry analyses. Our facility is one of the two primary centers for the State of Ohio Mass Spectrometry Consortium. Participating universities in this Consortium are the Ohio State Center, the Cincinnati Center, Akron, Toledo, Ohio University, Miami, Kent, Youngstown, as well as many other Ohio universities, clinics, and industrial laboratories. The University of Cincinnati Facility will not only provide access to the instruments at the Cincinnati Facility, but also all instruments at other participating universities. The Consortium is working to establish network links to allow rapid data transmission between various sites.
    Technical direction for the facility is provided by the Faculty Supervisor, Chemistry Professor Pat Limbach. Our staff, Dr.Stephen Macha and Dr. Larry Sallans maintain day-to-day operations in the facility. New users are invited to contact them to discuss your analysis needs at (513) 556-1575.
  • Mass Spectrometry Facility

    Kenneth Setchell, PhD

    The Mass Spectrometry Facility uses HPLC, FAB-MS, GC-MS and LC-MS/MS applications for screening and quantification of metabolites and drugs. Assays are fully validated to meet FDA/CAP requirements and the core operates under GLP standards and is CAP/CLIA accredited.
    We specialize in research programs focusing on hepatology, gastroenterology and nutrition with an emphasis on steroids, sterols and bile acids.
  • MEG and Neurophysiology Core

    Don Gilbert, MD

    We provide researchers with access to state of the art 275-channel whole head human magnetometry with data acquisition rates up to 12 kHz per channel. The system can also do simultaneous EEG recordings. We provide orientation to data collection with the magnetometer including a stimulus presentation computer for auditory, visual, somatosensory stimuli, and bimanual 5 finger response pads for task-based studies. 
  • Mouse Metabolic Phenotyping Center (MMPC)

    Erin Bartley, Program Coordinator

    The University of Cincinnati Mouse Metabolic Phenotyping Center is a comprehensive resource for the phenotypic characterization of mouse models pertaining to the study of diabetes and its complications. The Center is one of multiple Mouse Metabolic Phenotyping Centers supported by the National Institutes of Health (NIDDK)

    Our mission is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. 

    We specialize in the immunological aspects of Type I diabetes, measurement of various glucose and lipid metabolism parameters relevant to Type II diabetes as well as diabetic complications such as heart disease and obesity.

    UC MMPC Services
  • NMR/MRI Animal Imaging Lab

    Diana Lindquist, PhD

    This mouse imaging system and laboratory is own by the UC College of Medicine but is currently staffed and administered by experienced imaging personnel from Cincinnati Children's Hospital Medical Center.  The laboratory includes a fully equipped chemistry lab complete with fume hood as well as a Bruker 9.4T (400 MHz) vertical wide-bore system. 

    This system is capable of conventional high-resolution multinuclear NMR acquisitions, including z-gradient experiments, as well as magic-angle spinning 1H and 13C acquisitions of tissue samples. 

    A gradient insert and special microimaging coils allow for 1H, 23Na, 7Li, 31P, or 13C MR imaging or spectroscopy acquisitions from mice and very small rats.  The system is based on Bruker AVIII HD hardware.

    Types of analyses available include:
    • 400 MHz high-resolution NMR of extracts
    • 400 MHz magic angle spinning
    • Small animal imaging (mice and rats smaller than 150 g)
    • In vivo magnetic resonance spectroscopy of 1H, 31P, and 13C
    Location & Hours:
    The core is located in Medical Sciences Building Room 4106. The Director is available by appointment.
  • NMR-based Metabolomics Core

    Lindsey Romick-Rosendale

    The NMR-based Metabolomics Core will provide technology that will help clinical and basic scientists develop rapid detection methods, as well as elucidate the complex metabolic pathways involved in a number of diseases and infections. A more comprehensive understanding of metabolism can lead to such advances as a more personalized approach to drug therapies. We provide all NMR –related metabolomics services on human and animal cells, biopsies and biological fluids. We strive to foster collaborative efforts that will advance translational research using metabolomics approaches.
  • Nuclear Magnetic Resonance Facility

    Keyang Ding

    A modern Nuclear Magnetic Resonance (NMR) Facility exists in the department of chemistry. It currently houses a Bruker AVANCE NEO-400 with a Z-Grad BBFO (Z-Gradient Broadband and Fluorine Observe) ATM (Automatic Tune and Match) probe; a Bruker AV-400 with a Z-Grad BBFO ATM probe and an automatic sample changer; and a Bruker DMX-500 with Z-Grad triple and double resonance probes. The NMR facility is capable of proton, carbon-13 and other multi-nuclear NMR in one and two dimensions including DEPT (Distortionless Enhancement by Polarization Transfer), COSY (COrrelated SpectroscopY), NOESY (Nuclear Overhauser Enhancement SpectroscopY), HSQC (Heteronuclear Single-Quantum Coherence) and self-diffusion measurements and of triple resonance NMR of proteins in solution.
  • Ohio Center for Microfluidic Innovation (OCMI)

    Ian Papautsky

    The Ohio Center for Microfluidic Innovation (OCMI) at the University of Cincinnati was created by the Ohio 3rd Frontier Wright Projects Program, and provides a complete tool set needed to take microfluidic and point-of-care devices through the entire development process, from concept to pilot fabrication.
     
  • Pathology Research Core

    Our services include tissue trimming, processing and embedding, slide sectioning, H&E staining, special staining, immunohistochemistry, in situ hybridization, antibody or probe workup and electron microscopy. We will help you interpret results and, if desired, will collaborate on publications. 
  • Pediatric Language, Literacy & Speech Outcomes Lab

    Karla Washington

    Dr. Karla Washington is the Director of the Pediatric Language, Literacy & Speech (PedLLS) Outcomes Lab which is housed in the French East Building, University of Cincinnati. We employ the theoretical framework offered by the World Health Organization (WHO), the International Classification of Functioning, Disability and Health – Children and Youth (ICF-CY; WHO, 2007) to promote a broad view of health and well-being to guide our clinical and research practices in national and international settings.

    We are currently seeking PhD students who are interested in child language development and disorders with a focus on applying theory to clinical research practice. Prospective students should contact Dr. Washington at karla.washington@uc.edu.

    PedLLS Students Awards/Achievements
    1. Megan McDonald
      1. 2014-15 Students Preparing for Academic-Research Careers (SPARC) Award, American Speech-Language-Hearing Association: Validity and Reliability of the Intelligibility in Context Scale - Jamaican Creole 2014 SPARC Recipients
      2. 2014-15 Leadership Education in Neurodevelopmental and Related Disabilities (LEND) at CCHMC Trainee: Tuition and Research Stipend
    2. Lauren Mikhail
      1. 2014 Women in Science and Engineering (WISE) Scholar, University of Cincinnati WISE Scholars
    3. Lauren McKinney
      1. 2014-16 Yates Scholarship
    4. Caiti Waldo
      1. 2014-15 LEND at CCHMC Trainee: Tuition and Research Stipend
  • Plasma Spectrochemical Analysis and Metallomics Center

    This core facility specializes in the analysis of complex samples for elemental quantification and chemical
    speciation.
  • Pluripotent Stem Cell Facility

    James Wells, PhD

    We are dedicated to providing high-quality, well-characterized  and reliably archived human embryonic stem cells for distribution to researchers. Additionally, the facility will provide investigators with reagents and expertise for the generation of induced pluripotent stem cells (iPSCs) as well as expert training in the protocols and techniques for proper handling and manipulation of human pluripotent stem cells. Our mission is to facilitate all aspects of pluripotent stem cell experimentation to contribute to advancing stem cell therapies for human disease. 
  • Preclinical Imaging Core (PIC)

    Lisa Lemen, PhD

    The Core was established to provide non-invasive multimodal imaging capabilities optimized for rodent imaging to the UC research community. The facility specializes in micro-CT and micro-PET/SPECT for longitudinal research projects in small animal models, but also provides bioluminescence, fluorescence and planar x-ray imaging capabilites.  The Core actively supports research in cancer and other progressive diseases, and a variety of surgical and bioengineering projects. 


    Location and Hours:
    Vontz Center Rm 0330 (basement- restricted access - call lab 558-7930)
    M-F  8:30am-5pm; or as arranged


    Announcement  Sept 2018
    Bioluminescence and Fluorescence imaging services are now available to PIs within the UC-COM LAMS mouse facilities – mice housed in the LAMS Vontz and MSB facilities remain behind the barrier for their imaging sessions and are returned to their original rooms. Please contact the lab for further information. 
     
     
  • Pyrosequencing Core (CCHMC)

    Hong Ji, PhD

    Our shared facility specializes in measuring locus-specific DNA methylation, genetic variations and mutations in a high throughput fashion.
  • Research Flow Cytometry Core

    Sherry Thornton, PhD

    We will train you to use cytometers for your research. We provide cell sorting, data analysis, and even computer workstations. Once you’ve been trained by our staff, you may access our facilities 24 hours a day. 
  • Richard C. Elder X-Ray Crystallography Facility

    Jeanette Krause

    A Facility for the analysis of single crystal chemical crystallography. In 1986 the Chemistry Department formally established a Single Crystal X-ray Facility open to all researchers. In 2003, as a result of an NSF-MRI grant, the Facility was totally upgraded, housing a Bruker SMART6000 CCD diffractometer system.
    The Facility is intimately involved in graduate and undergraduate research. Also active in research projects with groups engaged in NSF-REU, NSF-URC, REWU-WISE and ACS-Project Seed sponsored programs.
  • Transgenic Animal and Genome Editing Core Facility

    Yueh-Chiang Hu, PhD

    We provide streamlined service from DNA to founder animals. We use the latest genome-editing technologies, such as CRISPR-Cas9 and TALEN, to generate animals carrying multiple knockout or knock-in alleles in a highly efficient and time-saving fashion. We also provide conventional approaches to generate transgenic mice by pronuclear microinjection and chimeric mice using embryonic stem cells. The facility has also undertaken several new initiatives including implementation of a fast CRISPR-Cas9 genetic screen system and generation of genetically modified rats. Other services available in the facility include cell targeting, targeting vector construction, sperm and embryo cryopreservation, BAC transgenics, ICSI, mouse recovery from cryopreserved sperm, and embryo transfer (re-derivation).
  • TRANSLATIONAL CORE LABS

    Lilith Reeves

    The Translational Core Labs include the Viral Vector Core, the Vector Production Facility, the Stem Cell Processing Lab, the Cell Manipulations Lab and the Translational Trial Development and Support Lab (TTDSL). We specialize in the translation and scale up of gene therapy and cell therapy including iPSC and HEK in addition to the patient testing associated with these trials.
  • Translational Trials Developmental and Support Laboratory (TTDSL)

    Scott Witting

    We coordinate and perform cellular and molecular testing required to document purity, function, clonal composition and overall safety of research preparations and preclinical and clinical samples. This is a CAP / CLIA-certified laboratory.
  • UC Biorepository (UCB)

    Kelsey Dillehay McKillip, PhD - Director

    The UC Biorepository (UCB) is a fee-for-service biospecimen procurement and storage facility that collects, stores, and dispenses high-quality human biospecimens in support of clinical, translational, and basic research. 

    The UCB provides access to a large and growing collection of biospecimens, including malignant tissues with matched normal tissue, blood, and urine. The UCB also provides fit-for-purpose prospective biospecimen procurement services tailored to study specific requirements. 

    Investigators who are interested in accessing banked biospecimen should complete a Sample Request Form.  For prospective collection services please contact Kelsey Dillehay McKillip.  
  • UC Histopathology Core Laboratory (UCHCL)

    Kelsey Dillehay McKillip, PhD - Technical Director

    The UC Histopathology Core Laboratory (UCHCL) is a CLIA certified, fee-for-service core facility in the Department of Pathology and Laboratory Medicine.  The mission of the UCHCL is to provide expertise and tissue histology services in support of clinical and research initiatives.

    Services:
    • Routine histology services - tissue processing, embedding, and sectioning
    • Histochemical staining
    • Immunohistochemical staining
    • Immunofluorescence
    • In situ hybridization
    • Tissue microarray construction
    • Whole slide digitial imaging
    • Access to archived diagnostic tissue for research purposes
  • UC Proteomics Laboratory (UCPL)

    Ken Greis, PhD., Director

    The UC Proteomics Laboratory (UCPL) is committed to providing collaborative expertise & services in proteomics & biological mass spectrometry both as fee-for-service and as grant supported partnerships.

    Routine Analyses
    • Comparative protein profiling by 2D gel
    • Protein identification by Mass Spectrometry
    • Characterization of Protein Complexes
    • Confirming and Mapping Protein Modification sites

    Advanced Services/Collaborative Projects
    • Comparative protein profiling by MS (SILAC, iTRAQ)
    • Label Free Quantitation using Data Independent Aquisition (DIA)
    • Global Profiling of Protein Modifications (e.g. phospho, ubiquitin)

    Technology development research
    • Additional Global PTM profiling
    • Complex MRM quantitation of targeted proteins
    • Enzyme assays and inhibitor screening

    Location & Hours:
    The UCPL is located in the Vontz Center for Molecular Studies 1208-1216. Staff are typically available M-F, 9A-6P to accept samples, but please call 513 558-4057 to confirm.  First time customers should include a discussion with the director or associate director prior to preparing samples.
  • University of Cincinnati Evaluation Services Center

    Audra Morrison, Assistant Director

    UCESC has functioned as an independent service center at the University of Cincinnati since 1996. UCESC provides research, evaluation, assessment, and consulting services to equip clients and partners to make data-based decisions for accountability, continuous quality improvement, program planning, and program and policy development. UCESC employs a collaborative model, starting with the pre-proposal phase, and has provided comprehensive external evaluation and research services to UC units, schools and school districts, higher education, professional development providers, childcare and early childhood education providers, and health-related and social service organizations. 
     
  • Vector Production Facility

    Bill Swaney

    We provide GMP-grade viral vectors, master cell banks and master viral banks in support of gene therapy trials. 
  • Veterinary Services

    Gary Keller, DVM

    We offer routine and specialized husbandry, surgical support and expert consultation on regulatory issues (IACUC submissions) and animal transfers.
  • Viral Vector Core

    William Swaney

    We provide research-grade retroviral lentiviral and adeno-associated virus vectors.